Ryuichi Mashima

3.1k total citations · 2 hit papers
51 papers, 2.4k citations indexed

About

Ryuichi Mashima is a scholar working on Physiology, Molecular Biology and Immunology. According to data from OpenAlex, Ryuichi Mashima has authored 51 papers receiving a total of 2.4k indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Physiology, 18 papers in Molecular Biology and 11 papers in Immunology. Recurrent topics in Ryuichi Mashima's work include Lysosomal Storage Disorders Research (17 papers), Trypanosoma species research and implications (8 papers) and Antioxidant Activity and Oxidative Stress (8 papers). Ryuichi Mashima is often cited by papers focused on Lysosomal Storage Disorders Research (17 papers), Trypanosoma species research and implications (8 papers) and Antioxidant Activity and Oxidative Stress (8 papers). Ryuichi Mashima collaborates with scholars based in Japan, Australia and United States. Ryuichi Mashima's co-authors include Torayuki Okuyama, Roland Stocker, Daisuke Aki, Hiroyuki Mori, Akihiko Yoshimura, Hideo Yasukawa, Hitomi Nishinakamura, Toshikatsu Hanada, Reiko Hanada and Takehiro Torisu and has published in prestigious journals such as Journal of Biological Chemistry, Circulation and Nature Medicine.

In The Last Decade

Ryuichi Mashima

49 papers receiving 2.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity

2004 517 citations Hiroyuki Mori, Toshikatsu Hanada et al. profile →
The role of lipoxygenases in pathophysiology; new insights and future perspectives

2015 315 citations Ryuichi Mashima, Torayuki Okuyama profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Ryuichi Mashima Japan	23	788	563	459	364	348	51	2.4k
Consuelo Amantini Italy	35	1.4k 1.8×	436 0.8×	352 0.8×	490 1.3×	100 0.3×	118	3.7k
Matthias Engel Germany	36	1.8k 2.3×	487 0.9×	355 0.8×	364 1.0×	139 0.4×	134	3.7k
Jeong Woo Park South Korea	28	1.6k 2.1×	527 0.9×	306 0.7×	372 1.0×	128 0.4×	121	3.2k
Huy Ong Canada	37	2.0k 2.5×	398 0.7×	580 1.3×	401 1.1×	402 1.2×	140	4.4k
Shinji Goto Japan	31	1.4k 1.8×	263 0.5×	265 0.6×	334 0.9×	218 0.6×	97	3.0k
Anna‐Mart Engelbrecht South Africa	28	1.2k 1.5×	193 0.3×	361 0.8×	358 1.0×	81 0.2×	102	2.6k
Eiji Warabi Japan	31	1.5k 1.9×	323 0.6×	438 1.0×	171 0.5×	85 0.2×	81	2.8k
Vasileia Ismini Alexaki Germany	35	1.6k 2.0×	806 1.4×	512 1.1×	504 1.4×	70 0.2×	70	3.8k
Keiichi Tasaka Japan	40	2.0k 2.5×	407 0.7×	519 1.1×	582 1.6×	177 0.5×	128	4.4k

Countries citing papers authored by Ryuichi Mashima

Since Specialization

Citations

This map shows the geographic impact of Ryuichi Mashima's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ryuichi Mashima with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ryuichi Mashima more than expected).

Fields of papers citing papers by Ryuichi Mashima

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ryuichi Mashima. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ryuichi Mashima. The network helps show where Ryuichi Mashima may publish in the future.

Co-authorship network of co-authors of Ryuichi Mashima

This figure shows the co-authorship network connecting the top 25 collaborators of Ryuichi Mashima. A scholar is included among the top collaborators of Ryuichi Mashima based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ryuichi Mashima. Ryuichi Mashima is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Mashima, Ryuichi. (2025). Per- and Polyfluoroalkyl Substances (PFAS): History, Current Concerns, and Future Outlook. Molecules. 30(22). 4415–4415.

Okuyama, Torayuki, et al.. (2022). LC-MS/MS-based enzyme assay for lysosomal acid lipase using dried blood spots. Molecular Genetics and Metabolism Reports. 33. 100913–100913. 1 indexed citations

Mashima, Ryuichi, Masamitsu Maekawa, Aya Narita, Torayuki Okuyama, & Nariyasu Mano. (2018). Elevation of plasma lysosphingomyelin-509 and urinary bile acid metabolite in Niemann-Pick disease type C-affected individuals. Molecular Genetics and Metabolism Reports. 15. 90–95. 11 indexed citations

Fukuhara, Yasuyuki, Naoko Fuji, Asami Hirakiyama, et al.. (2017). A molecular analysis of the GAA gene and clinical spectrum in 38 patients with Pompe disease in Japan. Molecular Genetics and Metabolism Reports. 14. 3–9. 34 indexed citations

Mashima, Ryuichi, et al.. (2017). Quantification of the enzyme activities of iduronate-2-sulfatase, N-acetylgalactosamine-6-sulfatase and N-acetylgalactosamine-4-sulfatase using liquid chromatography-tandem mass spectrometry. Molecular Genetics and Metabolism Reports. 14. 36–40. 7 indexed citations

Yamamoto, Toshiyuki, et al.. (2017). Aspartylglucosaminuria caused by a novel homozygous mutation in the AGA gene was identified by an exome-first approach in a patient from Japan. Brain and Development. 39(5). 422–425. 4 indexed citations

Mashima, Ryuichi & Torayuki Okuyama. (2017). Enzyme activities of α-glucosidase in Japanese neonates with pseudodeficiency alleles. Molecular Genetics and Metabolism Reports. 12. 110–114. 7 indexed citations

Kosuga, Motomichi, Ryuichi Mashima, Asami Hirakiyama, et al.. (2016). Molecular diagnosis of 65 families with mucopolysaccharidosis type II (Hunter syndrome) characterized by 16 novel mutations in the IDS gene: Genetic, pathological, and structural studies on iduronate-2-sulfatase. Molecular Genetics and Metabolism. 118(3). 190–197. 47 indexed citations

Mashima, Ryuichi, et al.. (2016). A selective detection of lysophosphatidylcholine in dried blood spots for diagnosis of adrenoleukodystrophy by LC-MS/MS. Molecular Genetics and Metabolism Reports. 7. 16–19. 9 indexed citations

10.

Kawamata, Aya, Akane Inoue, Hiroaki Hemmi, et al.. (2011). Dok-1 and Dok-2 deficiency induces osteopenia via activation of osteoclasts. Journal of Cellular Physiology. 226(12). 3087–3093. 8 indexed citations

11.

Mashima, Ryuichi, Kazuho Honda, Yi Yang, et al.. (2010). Mice lacking Dok-1, Dok-2, and Dok-3 succumb to aggressive histiocytic sarcoma. Laboratory Investigation. 90(9). 1357–1364. 44 indexed citations

12.

Sanada, Takahito, Giichi Takaesu, Ryuichi Mashima, et al.. (2008). FLN29 Deficiency Reveals Its Negative Regulatory Role in the Toll-like Receptor (TLR) and Retinoic Acid-inducible Gene I (RIG-I)-like Helicase Signaling Pathway. Journal of Biological Chemistry. 283(49). 33858–33864. 47 indexed citations

13.

Ohishi, Masanobu, Yumiko Matsumura, Daisuke Aki, et al.. (2005). Suppressors of Cytokine Signaling-1 and -3 Regulate Osteoclastogenesis in the Presence of Inflammatory Cytokines. The Journal of Immunology. 174(5). 3024–3031. 36 indexed citations

14.

Hanada, Toshikatsu, Kentaro Tanaka, Yumiko Matsumura, et al.. (2005). Induction of Hyper Th1 Cell-Type Immune Responses by Dendritic Cells Lacking the Suppressor of Cytokine Signaling-1 Gene. The Journal of Immunology. 174(7). 4325–4332. 87 indexed citations

15.

Mashima, Ryuichi, Kazuko Saeki, Daisuke Aki, et al.. (2005). FLN29, a Novel Interferon- and LPS-inducible Gene Acting as a Negative Regulator of Toll-like Receptor Signaling. Journal of Biological Chemistry. 280(50). 41289–41297. 53 indexed citations

16.

Kimura, Akiko, Ichiko Kinjyo, Yumiko Matsumura, et al.. (2004). SOCS3 Is a Physiological Negative Regulator for Granulopoiesis and Granulocyte Colony-stimulating Factor Receptor Signaling. Journal of Biological Chemistry. 279(8). 6905–6910. 98 indexed citations

17.

Mashima, Ryuichi, et al.. (2002). Plasmodium falciparum Histidine-rich Protein-2 (PfHRP2) Modulates the Redox Activity of Ferri-protoporphyrin IX (FePPIX). Journal of Biological Chemistry. 277(17). 14514–14520. 16 indexed citations

18.

Thomas, Shane R., et al.. (2001). Antioxidants Inhibit Indoleamine 2,3-Dioxygenase in IFN-γ-Activated Human Macrophages: Posttranslational Regulation by Pyrrolidine Dithiocarbamate. The Journal of Immunology. 166(10). 6332–6340. 94 indexed citations

19.

Mashima, Ryuichi, Paul K. Witting, & Roland Stocker. (2001). Oxidants and antioxidants in atherosclerosis. Current Opinion in Lipidology. 12(4). 411–418. 87 indexed citations

20.

Yamamoto, Yorihiro, N. Imai, Ryuichi Mashima, et al.. (2000). [3] Singlet oxygen from irradiated titanium dioxide and zinc oxide. Methods in enzymology on CD-ROM/Methods in enzymology. 319. 29–37. 45 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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