Curtis Huttenhower

171.9k citations

255 papers · 57.9k indexed · 33 hit papers · h-index 89

Molecular Biology top 0.01%
Infectious Diseases top 0.05%
Physiology top 0.1%
Ecology top 0.05%
Food Science top 0.02%

Co-authors: Nicola Segata Dirk Gevers Levi Waldron Jacques Izard Wendy S. Garrett Xochitl C. Morgan Rob Knight Eric A. Franzosa
Topics: Gut microbiota and health (135 papers)Genomics and Phylogenetic Studies (43 papers)Bioinformatics and Genomic Networks (33 papers)
Cited by: Biological Psychiatry Molecular Biology Periodontics
Journals: Nature Science Cell
Partner nations: United States United Kingdom Italy

In The Last Decade

Curtis Huttenhower

245 papers receiving 57.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Metagenomic biomarker discovery and explanation

2011 11.7k citations Nicola Segata, Jacques Izard et al. profile →
Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences

2013 7.1k citations Rob Knight, Curtis Huttenhower et al. profile →
Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment

2012 2.0k citations Dirk Gevers, Ramnik J. Xavier et al. profile →
Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis

2013 1.5k citations Nicola Segata, Curtis Huttenhower et al. eLife profile →
Genomic analysis identifies association of Fusobacterium with colorectal carcinoma

2011 1.4k citations Dirk Gevers, Shuji Ogino et al. profile →
Multivariable association discovery in population-scale meta-omics studies

2021 1.3k citations Himel Mallick, Lauren J. McIver et al. profile →
The healthy human microbiome

2016 1.2k citations Jason Lloyd‐Price, Galeb Abu-Ali et al. profile →
Metagenomic microbial community profiling using unique clade-specific marker genes

2012 1.2k citations Nicola Segata, Levi Waldron et al. profile →
Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3

2021 1.2k citations Francesco Beghini, Lauren J. McIver et al. eLife profile →
Microbial Co-occurrence Relationships in the Human Microbiome

2012 1.1k citations Jacques Izard, Nicola Segata et al. profile →
Species-level functional profiling of metagenomes and metatranscriptomes

2018 1.0k citations Eric A. Franzosa, Lauren J. McIver et al. profile →
Extensive Unexplored Human Microbiome Diversity Revealed by Over 150,000 Genomes from Metagenomes Spanning Age, Geography, and Lifestyle

2019 916 citations Edoardo Pasolli, Francesco Asnicar et al. Cell profile →
The Integrative Human Microbiome Project

2019 833 citations Jason Lloyd‐Price, Curtis Huttenhower et al. profile →
Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity

2016 826 citations Hera Vlamakis, Eric A. Franzosa et al. Cell profile →
Composition of the adult digestive tract bacterial microbiome based on seven mouth surfaces, tonsils, throat and stool samples

2012 816 citations Nicola Segata, Katherine P. Lemon et al. profile →
Strains, functions and dynamics in the expanded Human Microbiome Project

2017 804 citations Jason Lloyd‐Price, Eric A. Franzosa et al. profile →
Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis

2016 773 citations Curtis Huttenhower et al. Nature Communications profile →
Metabolic Reconstruction for Metagenomic Data and Its Application to the Human Microbiome \n

2012 723 citations Sahar Abubucker, Nicola Segata et al. Goce Delchev University Repository (Goce Delčev University of Štip) profile →
Natural history of the infant gut microbiome and impact of antibiotic treatment on bacterial strain diversity and stability

2016 714 citations Eric A. Franzosa, Hera Vlamakis et al. profile →
PhyloPhlAn is a new method for improved phylogenetic and taxonomic placement of microbes

2013 617 citations Nicola Segata, Curtis Huttenhower et al. Nature Communications profile →
Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease

2016 576 citations Dirk Gevers, Curtis Huttenhower et al. profile →
Compact graphical representation of phylogenetic data and metadata with GraPhlAn

2015 572 citations Francesco Asnicar, George Weingart et al. profile →
Cervicovaginal Bacteria Are a Major Modulator of Host Inflammatory Responses in the Female Genital Tract

2015 520 citations Curtis Huttenhower et al. profile →
A Metagenomic Approach to Characterization of the Vaginal Microbiome Signature in Pregnancy

2012 500 citations Nicola Segata, Dirk Gevers et al. profile →
Microbial strain-level population structure and genetic diversity from metagenomes

2017 488 citations Edoardo Pasolli, Curtis Huttenhower et al. profile →
Sequencing and beyond: integrating molecular 'omics' for microbial community profiling

2015 483 citations Eric A. Franzosa, Galeb Abu-Ali et al. profile →
Relating the metatranscriptome and metagenome of the human gut

2014 482 citations Eric A. Franzosa, Nicola Segata et al. Proceedings of the National Academy of Sciences profile →
Precise phylogenetic analysis of microbial isolates and genomes from metagenomes using PhyloPhlAn 3.0

2020 472 citations Francesco Asnicar, Andrew Maltez Thomas et al. Nature Communications profile →
Assessment of colorectal cancer molecular features along bowel subsites challenges the conception of distinct dichotomy of proximal versus distal colorectum

2012 427 citations Levi Waldron, Yujin Hoshida et al. profile →
Schrödinger’s microbes: Tools for distinguishing the living from the dead in microbial ecosystems

2017 335 citations Erica M. Hartmann, Curtis Huttenhower et al. profile →
The gut microbiome modulates the protective association between a Mediterranean diet and cardiometabolic disease risk

2021 236 citations Long H. Nguyen, Kerry L. Ivey et al. profile →
A bacterial bile acid metabolite modulates Treg activity through the nuclear hormone receptor NR4A1

2021 183 citations Yancong Zhang, Eric A. Franzosa et al. Cell Host & Microbe profile →
Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease

2023 95 citations Raaj S. Mehta, Jared R. Mayers et al. profile →

Peers

Countries citing papers authored by Curtis Huttenhower

Since Specialization

Citations

This map shows the geographic impact of Curtis Huttenhower's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Curtis Huttenhower with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Curtis Huttenhower more than expected).

Fields of papers citing papers by Curtis Huttenhower

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Curtis Huttenhower. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Curtis Huttenhower. The network helps show where Curtis Huttenhower may publish in the future.

Co-authorship network of co-authors of Curtis Huttenhower

This figure shows the co-authorship network connecting the top 25 collaborators of Curtis Huttenhower. A scholar is included among the top collaborators of Curtis Huttenhower based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Curtis Huttenhower. Curtis Huttenhower is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Capturing sequence ambiguity among taxa in a primer-specific manner to improve taxonomic classification of amplicon sequencing 2025 ·Nucleic Acids Research ·Jacob T. Nearing,Kelsey N. Thompson,Thomas Kuntz,(unknown),Amrisha Bhosle,Tobyn Branck,Dayakar V. Badri,Eric A. Franzosa,(unknown),Curtis Huttenhower,Meghan I. Short	0
2	A metabolomics pipeline highlights microbial metabolism in bloodstream infections 2024 ·Cell ·Jared R. Mayers,Jack Varon,(unknown),Martin Daniel-Ivad,(unknown),(unknown),Nathaniel R. Glasser,(unknown),Julie Ng,(unknown),Curtis Huttenhower,Mark A. Perrella,Clary B. Clish,Sihai Dave Zhao,Rebecca M. Baron,Emily P. Balskus	20
3	1245 INTERPLAY BETWEEN COFFEE INTAKE AND THE GUT MICROBIOME IN RELATION TO HOST METABOLOME 2023 ·Gastroenterology ·Kai Wang,Wenjie Ma,Hang Dong,Kelsey N. Thompson,Eric A. Franzosa,Francesco Asnicar,Eric B. Rimm,Wendy S. Garrett,Nicola Segata,Qi Sun,Andrew T. Chan,Curtis Huttenhower,Mingyang Song	0
4	Pulsed antibiotic treatments of gnotobiotic mice manifest in complex bacterial community dynamics and resistance effects 2023 ·Cell Host & Microbe ·Philipp C. Münch,Claudia Eberl,(unknown),Diana Ring,Adrian Fritz,Simone Herp,(unknown),Robert Geffers,Eric A. Franzosa,Curtis Huttenhower,Alice C. McHardy,Bärbel Stecher	7
5	Challenges and opportunities in sharing microbiome data and analyses 2023 ·Nature Microbiology ·Curtis Huttenhower,ROBERT FINN,Alice C. McHardy	30
6	Integrated molecular approaches for fermented food microbiome research 2023 ·FEMS Microbiology Reviews ·Aaron M. Walsh,John Leech,Curtis Huttenhower,(unknown),Fiona Crispie,Christian Chervaux,Paul D. Cotter	26
7	Human threat learning is associated with gut microbiota composition 2022 ·PNAS Nexus ·(unknown),Thomas Kuntz,(unknown),(unknown),(unknown),Bridget Callaghan,Curtis Huttenhower,Joseph E. LeDoux,Elizabeth A. Phelps	3
8	Density-based binning of gene clusters to infer function or evolutionary history using GeneGrouper 2021 ·Bioinformatics ·Alexander McFarland,Nolan W. Kennedy,Carolyn E. Mills,Danielle Tullman‐Ercek,Curtis Huttenhower,Erica M. Hartmann	3
9	Microbiome Analysis of More Than 2,000 NHS Bowel Cancer Screening Programme Samples Shows the Potential to Improve Screening Accuracy 2021 ·Clinical Cancer Research ·Caroline Young,Henry M. Wood,(unknown),(unknown),(unknown),(unknown),Sally C. Benton,(unknown),(unknown),(unknown),Kelsey N. Thompson,Yan Yan,Jennifer H. Barrett,Eva Morris,Curtis Huttenhower,Philip Quirke	21
10	Statistical approaches for differential expression analysis in metatranscriptomics 2021 ·Bioinformatics ·Yancong Zhang,Kelsey N. Thompson,Curtis Huttenhower,Eric A. Franzosa	32
11	Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3breakdown → 2021 ·eLife ·Francesco Beghini,Lauren J. McIver,Aitor Blanco‐Míguez,Léonard Dubois,Francesco Asnicar,Sagun Maharjan,(unknown),Paolo Manghi,Matthias Scholz,Andrew Maltez Thomas,Mireia Valles‐Colomer,George Weingart,Yancong Zhang,Moreno Zolfo,Curtis Huttenhower,Eric A. Franzosa,Nicola Segata	1173
12	The oral microbiome in relation to pancreatic cancer risk in African Americans 2021 ·British Journal of Cancer ·Jessica L. Petrick,Jeremy E. Wilkinson,Dominique S. Michaud,Qiuyin Cai,Hanna Gerlovin,Lisa B. Signorello,Brian M. Wolpin,Edward Ruiz-Narváez,Jirong Long,Yaohua Yang,W. Evan Johnson,Xiao‐Ou Shu,Curtis Huttenhower,Julie R. Palmer	21
13	Precise phylogenetic analysis of microbial isolates and genomes from metagenomes using PhyloPhlAn 3.0breakdown → 2020 ·Nature Communications ·Francesco Asnicar,Andrew Maltez Thomas,Francesco Beghini,Claudia Mengoni,Serena Manara,Paolo Manghi,Qiyun Zhu,Mattia Bolzan,Fabio Cumbo,(unknown),Jon G. Sanders,Moreno Zolfo,Evguenia Kopylova,Edoardo Pasolli,Rob Knight,Siavash Mirarab,Curtis Huttenhower,Nicola Segata	472
14	Growth effects of N-acylethanolamines on gut bacteria reflect altered bacterial abundances in inflammatory bowel disease 2020 ·Nature Microbiology ·Nadine Fornelos,Eric A. Franzosa,Jason Bishai,John W. Annand,Akihiko Oka,Jason Lloyd‐Price,Timothy D. Arthur,Ashley Garner,Julián Ávila-Pacheco,Henry J. Haiser,Andrew C. Tolonen,Jeffrey A. Porter,Clary B. Clish,R. Balfour Sartor,Curtis Huttenhower,Hera Vlamakis,Ramnik J. Xavier	74
15	Stability of the human faecal microbiome in a cohort of adult men 2018 ·Nature Microbiology ·Raaj S. Mehta,Galeb Abu-Ali,David A. Drew,Jason Lloyd‐Price,Ayshwarya Subramanian,Paul Lochhead,Amit D. Joshi,Kerry L. Ivey,Hamed Khalili,Gordon Brown,Casey DuLong,Mingyang Song,Long H. Nguyen,Himel Mallick,Eric B. Rimm,Jacques Izard,Curtis Huttenhower,Andrew T. Chan	193
16	Identifying personal microbiomes using metagenomic codes 2015 ·Proceedings of the National Academy of Sciences ·Eric A. Franzosa,Katherine Huang,James Meadow,Dirk Gevers,Katherine P. Lemon,Brendan J. M. Bohannan,Curtis Huttenhower	320
17	Reprograming of gut microbiome energy metabolism by the FUT2 Crohn’s disease risk polymorphism 2014 ·The ISME Journal ·Maomeng Tong,Ian McHardy,Paul Ruegger,Maryam Goudarzi,Purna Kashyap,Talin Haritunians,Xiaoxiao Li,Thomas G. Graeber,Emma Schwager,Curtis Huttenhower,Albert J. Fornace,Justin L. Sonnenburg,Dermot McGovern,James Borneman,Jonathan Braun	159
18	Expression Profiling of Archival Tumors for Long-term Health Studies 2012 ·Clinical Cancer Research ·Levi Waldron,Shuji Ogino,Yujin Hoshida,Kaori Shima,Amy E. McCart Reed,Peter T. Simpson,Yoshifumi Baba,Katsuhiko Nosho,Nicola Segata,Ana Cristina Vargas,Margaret C. Cummings,Sunil R. Lakhani,Gregory J. Kirkner,Edward L. Giovannucci,John Quackenbush,Todd R. Golub,Charles S. Fuchs,Giovanni Parmigiani,Curtis Huttenhower	25
19	Metabolic Reconstruction for Metagenomic Data and Its Application to the Human Microbiome \nbreakdown → 2012 ·Goce Delchev University Repository (Goce Delčev University of Štip) ·Sahar Abubucker,Nicola Segata,Johannes B. Goll,Alyxandria M. Schubert,Jacques Izard,Brandi L. Cantarel,Beltran Rodriguez-Mueller,Jeremy Zucker,Mathangi Thiagarajan,Bernard Henrissat,Owen White,Scott T. Kelley,Barbara A. Methé,Patrick D. Schloss,Dirk Gevers,Makedonka Mitreva,Curtis Huttenhower	723
20	Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry 2007 ·Proceedings of the National Academy of Sciences ·An Chi,Curtis Huttenhower,Lewis Y. Geer,Joshua J. Coon,John E. P. Syka,Dina L. Bai,Jeffrey Shabanowitz,Daniel J. Burke,Olga G. Troyanskaya,Donald F. Hunt	460

About Curtis Huttenhower

Curtis Huttenhower is a scholar working on Molecular Biology, Periodontics and Food Science, having authored 255 papers that have together received 57.9k indexed citations. Recurring topics across this work include Gut microbiota and health (135 papers), Genomics and Phylogenetic Studies (43 papers) and Bioinformatics and Genomic Networks (33 papers). The work is most often cited by research in Biological Psychiatry (1.8k citations), Molecular Biology (38.0k citations) and Periodontics (2.4k citations). Curtis Huttenhower has collaborated with scholars based in United States, United Kingdom and Italy. Frequent co-authors include Nicola Segata, Dirk Gevers, Levi Waldron, Jacques Izard, Wendy S. Garrett, Xochitl C. Morgan, Rob Knight, Eric A. Franzosa, J. Gregory Caporaso and Dan Knights. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact