Curtis Huttenhower

171.9k total citations · 33 hit papers
255 papers, 57.9k citations indexed

About

Curtis Huttenhower is a scholar working on Molecular Biology, Physiology and Ecology. According to data from OpenAlex, Curtis Huttenhower has authored 255 papers receiving a total of 57.9k indexed citations (citations by other indexed papers that have themselves been cited), including 196 papers in Molecular Biology, 37 papers in Physiology and 32 papers in Ecology. Recurrent topics in Curtis Huttenhower's work include Gut microbiota and health (135 papers), Genomics and Phylogenetic Studies (43 papers) and Bioinformatics and Genomic Networks (33 papers). Curtis Huttenhower is often cited by papers focused on Gut microbiota and health (135 papers), Genomics and Phylogenetic Studies (43 papers) and Bioinformatics and Genomic Networks (33 papers). Curtis Huttenhower collaborates with scholars based in United States, United Kingdom and Italy. Curtis Huttenhower's co-authors include Nicola Segata, Dirk Gevers, Levi Waldron, Jacques Izard, Wendy S. Garrett, Xochitl C. Morgan, Rob Knight, Eric A. Franzosa, J. Gregory Caporaso and Dan Knights and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Curtis Huttenhower

245 papers receiving 57.3k citations

Hit Papers

Metagenomic biomarker dis... 2011 2026 2016 2021 2011 2013 2012 2013 2011 2.5k 5.0k 7.5k 10.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Metagenomic biomarker discovery and explanation
    2011 11.7k citations Nicola Segata, Jacques Izard et al. profile →
  2. Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences
    2013 7.1k citations Morgan G. I. Langille, Rob Knight et al. profile →
  3. Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment
    2012 2.0k citations Xochitl C. Morgan, Dirk Gevers et al. profile →
  4. Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis
    2013 1.5k citations Nicola Segata, Curtis Huttenhower et al. profile →
  5. Genomic analysis identifies association of Fusobacterium with colorectal carcinoma
    2011 1.4k citations Dirk Gevers, Monia Michaud et al. profile →
  6. Multivariable association discovery in population-scale meta-omics studies
    2021 1.3k citations Himel Mallick, Yancong Zhang et al. profile →
  7. The healthy human microbiome
    2016 1.2k citations Jason Lloyd‐Price, Galeb Abu-Ali et al. profile →
  8. Metagenomic microbial community profiling using unique clade-specific marker genes
    2012 1.2k citations Nicola Segata, Levi Waldron et al. profile →
  9. Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3
    2021 1.2k citations Yancong Zhang, Curtis Huttenhower et al. profile →
  10. Microbial Co-occurrence Relationships in the Human Microbiome
    2012 1.1k citations Karoline Faust, J. Fah Sathirapongsasuti et al. profile →
  11. Species-level functional profiling of metagenomes and metatranscriptomes
    2018 1.0k citations Eric A. Franzosa, Rob Knight et al. profile →
  12. Extensive Unexplored Human Microbiome Diversity Revealed by Over 150,000 Genomes from Metagenomes Spanning Age, Geography, and Lifestyle
    2019 916 citations Casey DuLong, Xochitl C. Morgan et al. profile →
  13. The Integrative Human Microbiome Project
    2019 833 citations Jason Lloyd‐Price, Curtis Huttenhower et al. profile →
  14. Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity
    2016 826 citations Eric A. Franzosa, Curtis Huttenhower et al. profile →
  15. Composition of the adult digestive tract bacterial microbiome based on seven mouth surfaces, tonsils, throat and stool samples
    2012 816 citations Nicola Segata, Katherine P. Lemon et al. profile →
  16. Strains, functions and dynamics in the expanded Human Microbiome Project
    2017 804 citations Jason Lloyd‐Price, Eric A. Franzosa et al. profile →
  17. Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis
    2016 773 citations Curtis Huttenhower et al. profile →
  18. Metabolic Reconstruction for Metagenomic Data and Its Application to the Human Microbiome \n
    2012 723 citations Sahar Abubucker, Nicola Segata et al. Goce Delchev University Repository (Goce Delčev University of Štip) profile →
  19. Natural history of the infant gut microbiome and impact of antibiotic treatment on bacterial strain diversity and stability
    2016 714 citations Eric A. Franzosa, Curtis Huttenhower et al. profile →
  20. PhyloPhlAn is a new method for improved phylogenetic and taxonomic placement of microbes
    2013 617 citations Nicola Segata, Xochitl C. Morgan et al. profile →
  21. Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease
    2016 576 citations Dirk Gevers, Curtis Huttenhower et al. profile →
  22. Compact graphical representation of phylogenetic data and metadata with GraPhlAn
    2015 572 citations Curtis Huttenhower, Nicola Segata et al. profile →
  23. Cervicovaginal Bacteria Are a Major Modulator of Host Inflammatory Responses in the Female Genital Tract
    2015 520 citations Curtis Huttenhower et al. profile →
  24. A Metagenomic Approach to Characterization of the Vaginal Microbiome Signature in Pregnancy
    2012 500 citations Nicola Segata, Dirk Gevers et al. profile →
  25. Microbial strain-level population structure and genetic diversity from metagenomes
    2017 488 citations Curtis Huttenhower, Nicola Segata et al. profile →
  26. Sequencing and beyond: integrating molecular 'omics' for microbial community profiling
    2015 483 citations Eric A. Franzosa, Tiffany Hsu et al. profile →
  27. Relating the metatranscriptome and metagenome of the human gut
    2014 482 citations Eric A. Franzosa, Xochitl C. Morgan et al. Proceedings of the National Academy of Sciences profile →
  28. Precise phylogenetic analysis of microbial isolates and genomes from metagenomes using PhyloPhlAn 3.0
    2020 472 citations Rob Knight, Curtis Huttenhower et al. profile →
  29. Assessment of colorectal cancer molecular features along bowel subsites challenges the conception of distinct dichotomy of proximal versus distal colorectum
    2012 427 citations Levi Waldron, Yujin Hoshida et al. profile →
  30. Schrödinger’s microbes: Tools for distinguishing the living from the dead in microbial ecosystems
    2017 335 citations Erica M. Hartmann, Tiffany Hsu et al. Microbiome profile →
  31. The gut microbiome modulates the protective association between a Mediterranean diet and cardiometabolic disease risk
    2021 236 citations Dong D. Wang, Long H. Nguyen et al. profile →
  32. A bacterial bile acid metabolite modulates Treg activity through the nuclear hormone receptor NR4A1
    2021 183 citations Yancong Zhang, Eric A. Franzosa et al. profile →
  33. Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease
    2023 95 citations Raaj S. Mehta, Yancong Zhang et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Curtis Huttenhower United States 89 38.0k 8.0k 7.6k 7.4k 5.8k 255 57.9k
Dirk Gevers United States 68 26.2k 0.7× 6.4k 0.8× 4.6k 0.6× 7.4k 1.0× 5.6k 1.0× 94 42.6k
Frederic D. Bushman United States 107 30.5k 0.8× 12.7k 1.6× 5.0k 0.7× 4.7k 0.6× 2.5k 0.4× 370 48.6k
Peter J. Turnbaugh United States 61 50.6k 1.3× 10.2k 1.3× 22.1k 2.9× 6.4k 0.9× 8.5k 1.5× 129 72.2k
David A. Relman United States 83 24.9k 0.7× 8.6k 1.1× 4.7k 0.6× 5.3k 0.7× 5.1k 0.9× 249 43.8k
Ruth E. Ley United States 71 51.4k 1.4× 11.3k 1.4× 19.9k 2.6× 6.0k 0.8× 9.1k 1.6× 150 74.2k
Wendy S. Garrett United States 57 24.3k 0.6× 5.5k 0.7× 5.9k 0.8× 2.6k 0.3× 3.6k 0.6× 112 39.2k
Catherine Lozupone United States 56 28.3k 0.7× 5.7k 0.7× 6.4k 0.8× 12.4k 1.7× 4.8k 0.8× 104 48.8k
Nicola Segata Italy 62 22.3k 0.6× 5.1k 0.6× 4.5k 0.6× 5.2k 0.7× 4.2k 0.7× 199 34.4k
Susan Holmes United States 60 23.9k 0.6× 4.5k 0.6× 3.8k 0.5× 13.8k 1.9× 3.7k 0.6× 189 52.9k
José C. Clemente United States 54 21.9k 0.6× 4.9k 0.6× 4.7k 0.6× 8.0k 1.1× 3.6k 0.6× 135 38.2k

Countries citing papers authored by Curtis Huttenhower

Since Specialization
Citations

This map shows the geographic impact of Curtis Huttenhower's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Curtis Huttenhower with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Curtis Huttenhower more than expected).

Fields of papers citing papers by Curtis Huttenhower

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Curtis Huttenhower. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Curtis Huttenhower. The network helps show where Curtis Huttenhower may publish in the future.

Co-authorship network of co-authors of Curtis Huttenhower

This figure shows the co-authorship network connecting the top 25 collaborators of Curtis Huttenhower. A scholar is included among the top collaborators of Curtis Huttenhower based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Curtis Huttenhower. Curtis Huttenhower is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Nakatsu, Geicho, Monia Michaud, Eric A. Franzosa, et al.. (2025). Virulence factor discovery identifies associations between the Fic gene family and Fap2 + fusobacteria in colorectal cancer microbiomes. mBio. 16(2). e0373224–e0373224. 7 indexed citations
2.
Hsu, Tiffany, Chengwei Luo, Robert G. Beiko, et al.. (2025). Profiling lateral gene transfer events in the human microbiome using WAAFLE. Nature Microbiology. 10(1). 94–111. 6 indexed citations
3.
Ma, Wenjie, Fenglei Wang, Long Hoang Nguyen, et al.. (2024). F. prausnitzii potentially modulates the association between citrus intake and depression. Microbiome. 12(1). 237–237. 7 indexed citations
4.
Hughes, Riley, Cara L. Frankenfeld, Daryl M. Gohl, et al.. (2023). Methods in Nutrition & Gut Microbiome Research: An American Society for Nutrition Satellite Session [13 October 2022]. Nutrients. 15(11). 2451–2451. 3 indexed citations
5.
Walsh, Aaron M., John Leech, Curtis Huttenhower, et al.. (2023). Integrated molecular approaches for fermented food microbiome research. FEMS Microbiology Reviews. 47(2). 26 indexed citations
6.
Zhang, Yancong, Kelsey N. Thompson, Curtis Huttenhower, & Eric A. Franzosa. (2021). Statistical approaches for differential expression analysis in metatranscriptomics. Bioinformatics. 37(Supplement_1). i34–i41. 32 indexed citations
7.
McFarland, Alexander, Nolan W. Kennedy, Carolyn E. Mills, et al.. (2021). Density-based binning of gene clusters to infer function or evolutionary history using GeneGrouper. Bioinformatics. 38(3). 612–620. 3 indexed citations
8.
Young, Caroline, Henry M. Wood, Sally C. Benton, et al.. (2021). Microbiome Analysis of More Than 2,000 NHS Bowel Cancer Screening Programme Samples Shows the Potential to Improve Screening Accuracy. Clinical Cancer Research. 27(8). 2246–2254. 21 indexed citations
9.
McGee, Jean S. & Curtis Huttenhower. (2021). Of mice and men and women: Sexual dimorphism of the gut microbiome. International Journal of Women’s Dermatology. 7(5). 533–538. 19 indexed citations
10.
McBurney, Michael I., Cindy D. Davis, Claire M. Fraser, et al.. (2019). Establishing What Constitutes a Healthy Human Gut Microbiome: State of the Science, Regulatory Considerations, and Future Directions. Journal of Nutrition. 149(11). 1882–1895. 186 indexed citations
11.
Abu-Ali, Galeb, Raaj S. Mehta, Jason Lloyd‐Price, et al.. (2018). Metatranscriptome of human faecal microbial communities in a cohort of adult men. Nature Microbiology. 3(3). 356–366. 156 indexed citations
12.
Faust, Karoline, Gipsi Lima‐Mendez, J. Fah Sathirapongsasuti, et al.. (2015). Cross-biome comparison of microbial association networks. Frontiers in Microbiology. 6. 1200–1200. 139 indexed citations
13.
Franzosa, Eric A., Katherine Huang, James Meadow, et al.. (2015). Identifying personal microbiomes using metagenomic codes. Proceedings of the National Academy of Sciences. 112(22). E2930–8. 320 indexed citations
14.
Tong, Maomeng, Ian McHardy, Paul Ruegger, et al.. (2014). Reprograming of gut microbiome energy metabolism by the FUT2 Crohn’s disease risk polymorphism. The ISME Journal. 8(11). 2193–2206. 159 indexed citations
15.
Waldron, Levi, Benjamin Haibe‐Kains, Aedín C. Culhane, et al.. (2014). Comparative Meta-analysis of Prognostic Gene Signatures for Late-Stage Ovarian Cancer. JNCI Journal of the National Cancer Institute. 106(5). 87 indexed citations
16.
Cordy, Regina Joice, Koji Yasuda, Afrah Shafquat, Xochitl C. Morgan, & Curtis Huttenhower. (2014). Determining Microbial Products and Identifying Molecular Targets in the Human Microbiome. Cell Metabolism. 20(5). 731–741. 76 indexed citations
17.
Waldron, Levi, Shuji Ogino, Yujin Hoshida, et al.. (2012). Expression Profiling of Archival Tumors for Long-term Health Studies. Clinical Cancer Research. 18(22). 6136–6146. 25 indexed citations
18.
Abubucker, Sahar, Nicola Segata, Johannes B. Goll, et al.. (2012). Metabolic Reconstruction for Metagenomic Data and Its Application to the Human Microbiome \n. Goce Delchev University Repository (Goce Delčev University of Štip). 723 indexed citations breakdown →
19.
Pop, Ana-Roxana, Curtis Huttenhower, Anjali S. Iyer‐Pascuzzi, Philip N. Benfey, & Olga G. Troyanskaya. (2010). Integrated functional networks of process, tissue, and developmental stage specific interactions in Arabidopsis thaliana. BMC Systems Biology. 4(1). 180–180. 19 indexed citations
20.
Chi, An, Curtis Huttenhower, Lewis Y. Geer, et al.. (2007). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry. Proceedings of the National Academy of Sciences. 104(7). 2193–2198. 460 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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