Christopher W. Carreras

2.0k citations

35 papers · 1.5k indexed · 1 hit paper · h-index 17

Co-authors: Daniel V. Santi Chaitan Khosla Marc Navre Dominique Charmot Yaoquan Liu David C. Myles Samantha Koo-McCoy Jeffrey Jacobs
Topics: Microbial Natural Products and Biosynthesis (8 papers)Biochemical and Molecular Research (8 papers)Enzyme Structure and Function (5 papers)
Cited by: Molecular Biology Pharmacology Nephrology
Journals: Proceedings of the National Academy of Sciences Journal of the American Chemical Society Journal of Biological Chemistry
Partner nations: United States South Korea Italy

In The Last Decade

Christopher W. Carreras

34 papers receiving 1.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

THE CATALYTIC MECHANISM AND STRUCTURE OF THYMIDYLATE SYNTHASE

1995 631 citations Christopher W. Carreras, Daniel V. Santi profile →

Peers

Countries citing papers authored by Christopher W. Carreras

Since Specialization

Citations

This map shows the geographic impact of Christopher W. Carreras's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher W. Carreras with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher W. Carreras more than expected).

Fields of papers citing papers by Christopher W. Carreras

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher W. Carreras. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher W. Carreras. The network helps show where Christopher W. Carreras may publish in the future.

Co-authorship network of co-authors of Christopher W. Carreras

This figure shows the co-authorship network connecting the top 25 collaborators of Christopher W. Carreras. A scholar is included among the top collaborators of Christopher W. Carreras based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christopher W. Carreras. Christopher W. Carreras is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	A platform technology for ultra-long acting intratumoral therapy 2024 ·Scientific Reports ·Jeff Henise,John A. Hangasky,Deborah H. Charych,Christopher W. Carreras,Gary W. Ashley,Daniel V. Santi	4
2	A Very Long-acting Exatecan and Its Synergism with DNA Damage Response Inhibitors 2023 ·Cancer Research Communications ·Shaun D. Fontaine,Christopher W. Carreras,Ralph R. Reid,Gary W. Ashley,Daniel V. Santi	2
3	Design of Gut-Restricted Thiazolidine Agonists of G Protein-Coupled Bile Acid Receptor 1 (GPBAR1, TGR5) 2018 ·Journal of Medicinal Chemistry ·Tao Chen,(unknown),Noah Bell,Patricia D. Finn,David Rodríguez,Jill Kohler,Kenji Kozuka,Limin He,Andrew Spencer,Dominique Charmot,Marc Navre,Christopher W. Carreras,Samantha Koo-McCoy,(unknown),Jeremy S. Caldwell,Jeffrey Jacobs,Jason G. Lewis	28
4	Intestinal Inhibition of the Na ⁺ /H ⁺ Exchanger 3 Prevents Cardiorenal Damage in Rats and Inhibits Na ⁺ Uptake in Humans 2014 ·Science Translational Medicine ·Andrew Spencer,Eric D. Labonté,David P. Rosenbaum,Craig F. Plato,Christopher W. Carreras,Michael R. Leadbetter,Kenji Kozuka,Jill Kohler,Samantha Koo-McCoy,Limin He,Noah Bell,(unknown),(unknown),Marc Navre,Jeffrey Jacobs,Dominique Charmot	126
5	Gastrointestinal Inhibition of Sodium-Hydrogen Exchanger 3 Reduces Phosphorus Absorption and Protects against Vascular Calcification in CKD 2014 ·Journal of the American Society of Nephrology ·Eric D. Labonté,Christopher W. Carreras,Michael R. Leadbetter,Kenji Kozuka,Jill Kohler,Samantha Koo-McCoy,Limin He,Edward E. Dy,(unknown),Ziyang Zhong,Ingrid Langsetmo,Andrew Spencer,Noah Bell,(unknown),Marc Navre,Jason G. Lewis,Jeffrey Jacobs,Dominique Charmot	86
6	The role of the 4′′-hydroxyl on motilin agonist potency in the 9-dihydroerythromycin series 2011 ·Bioorganic & Medicinal Chemistry Letters ·Yaoquan Liu,Christopher W. Carreras,(unknown),David C. Myles,Simon J. Shaw	3
7	9-Dihydroerythromycins as non-antibiotic motilin receptor agonists 2010 ·Bioorganic & Medicinal Chemistry Letters ·Yaoquan Liu,Yong Li,Yue Chen,Hao Zheng,(unknown),David C. Myles,Christopher W. Carreras	3
8	9-Dihydroerythromycin ethers as motilin agonists—Developing structure–activity relationships for potency and safety 2010 ·Bioorganic & Medicinal Chemistry ·Yaoquan Liu,Yong Li,David C. Myles,(unknown),Christopher W. Carreras,Simon J. Shaw	4
9	Synthesis and biological activities of novel 17-aminogeldanamycin derivatives 2004 ·Bioorganic & Medicinal Chemistry ·Zong‐Qiang Tian,Yaoquan Liu,Dan Zhang,Zhan Wang,Steven D. Dong,Christopher W. Carreras,Yiqing Zhou,Giulio Rastelli,Daniel V. Santi,David C. Myles	128
10	Filter binding assay for the geldanamycin–heat shock protein 90 interaction 2003 ·Analytical Biochemistry ·Christopher W. Carreras,Andreas Schirmer,Ziyang Zhong,Daniel V. Santi	26
11	Genetically Engineered Analogs of Ascomycin for Nerve Regeneration 2002 ·Journal of Pharmacology and Experimental Therapeutics ·W. Peter Revill,Jan Voda,(unknown),Loleta Chung,Andreas Schirmer,Gary W. Ashley,John R. Carney,Maria Fardis,Christopher W. Carreras,Ye Zhou,Feng Lin,Elizabeth M. Tucker,Daniel P. Robinson,Bruce G. Gold	41
12	Stable Expression of a Synthetic Gene for the Human Motilin Receptor: Use in an Aequorin-Based Receptor Activation Assay 2002 ·Analytical Biochemistry ·Christopher W. Carreras,Michael A. Siani,Daniel V. Santi,Susan B. Dillon	8
13	An FKBP12 Binding Assay Based upon Biotinylated FKBP12 2001 ·Analytical Biochemistry ·Christopher W. Carreras,(unknown),Daniel V. Santi	5
14	Manipulation of polyketide biosynthesis for new drug discovery 2000 ·Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions ·Christopher W. Carreras,Gary W. Ashley	2
15	Development and screening of a polyketide virtual library for drug leads against a motilide pharmacophore 2000 ·Journal of Molecular Graphics and Modelling ·Michael A. Siani,A. Geoffrey Skillman,Christopher W. Carreras,Gary W. Ashley,Irwin D. Kuntz,Daniel V. Santi	7
16	Precursor‐Directed Biosynthesis of 6‐Deoxyerythronolide B Analogs in Streptomycescoelicolor: Understanding Precursor Effects 2000 ·Biotechnology Progress ·Timothy Leaf,(unknown),Christopher W. Carreras,Rika Regentin,(unknown),(unknown),Gary W. Ashley,Peter Licari	22
17	Structures of thymidylate synthase with a C-terminal deletion: Role of the C-terminus in alignment of 2'-deoxyuridine 5'-monophosphate and 5,10-methylenetetrahydrofolate 1993 ·Biochemistry ·Kathy M. Perry,Christopher W. Carreras,Louise Chang,Daniel V. Santi,Robert M. Stroud	47
18	Interaction of thymidylate synthase with pyridoxal 5'-phosphate as studied by UV/visible difference spectroscopy and molecular modeling 1993 ·Biochemistry ·Daniel V. Santi,(unknown),Anthony K. Tan,(unknown),Thomas S. Scanlan,Christopher W. Carreras	13
19	Thymidylate synthase with a C-terminal deletion catalyzes partial reactions but is unable to catalyze thymidylate formation 1992 ·Biochemistry ·Christopher W. Carreras,Shane Climie,Daniel V. Santi	20
20	Complete replacement set of amino acids at the C-terminus of thymidylate synthase: quantitative structure-activity relationship of mutants of an enzyme 1992 ·Biochemistry ·Shane Climie,Christopher W. Carreras,Daniel V. Santi	27

About Christopher W. Carreras

Christopher W. Carreras is a scholar working on Gastroenterology, Pharmacology and Molecular Biology, having authored 35 papers that have together received 1.5k indexed citations. Recurring topics across this work include Microbial Natural Products and Biosynthesis (8 papers), Biochemical and Molecular Research (8 papers) and Enzyme Structure and Function (5 papers). The work is most often cited by research in Molecular Biology (1.1k citations), Pharmacology (243 citations) and Nephrology (99 citations). Christopher W. Carreras has collaborated with scholars based in United States, South Korea and Italy. Frequent co-authors include Daniel V. Santi, Daniel V. Santi, Chaitan Khosla, Marc Navre, Dominique Charmot, Yaoquan Liu, David C. Myles, Samantha Koo-McCoy, Jeffrey Jacobs and Jill Kohler. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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