Christopher W. Carreras

2.0k total citations · 1 hit paper
35 papers, 1.5k citations indexed

About

Christopher W. Carreras is a scholar working on Molecular Biology, Oncology and Pharmacology. According to data from OpenAlex, Christopher W. Carreras has authored 35 papers receiving a total of 1.5k indexed citations (citations by other indexed papers that have themselves been cited), including 29 papers in Molecular Biology, 9 papers in Oncology and 8 papers in Pharmacology. Recurrent topics in Christopher W. Carreras's work include Microbial Natural Products and Biosynthesis (8 papers), Biochemical and Molecular Research (8 papers) and Enzyme Structure and Function (5 papers). Christopher W. Carreras is often cited by papers focused on Microbial Natural Products and Biosynthesis (8 papers), Biochemical and Molecular Research (8 papers) and Enzyme Structure and Function (5 papers). Christopher W. Carreras collaborates with scholars based in United States, South Korea and Italy. Christopher W. Carreras's co-authors include Daniel V. Santi, Daniel V. Santi, Chaitan Khosla, Noah Bell, Jeffrey Jacobs, Andrew Spencer, Yaoquan Liu, Marc Navre, David C. Myles and Samantha Koo-McCoy and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Journal of Biological Chemistry.

In The Last Decade

Christopher W. Carreras

34 papers receiving 1.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

THE CATALYTIC MECHANISM AND STRUCTURE OF THYMIDYLATE SYNTHASE

1995 631 citations Christopher W. Carreras, Daniel V. Santi profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Christopher W. Carreras United States	17	1.1k	309	263	243	142	35	1.5k
E. Marinello Italy	19	1.1k 1.0×	395 1.3×	67 0.3×	60 0.2×	45 0.3×	149	2.0k
Jan W. Vrijbloed Switzerland	25	1.1k 1.0×	141 0.5×	104 0.4×	225 0.9×	185 1.3×	41	1.6k
Xuben Hou China	24	1.3k 1.1×	325 1.1×	92 0.3×	112 0.5×	431 3.0×	86	1.9k
N.O. Concha United States	17	1.2k 1.1×	182 0.6×	135 0.5×	207 0.9×	164 1.2×	23	2.0k
Mamoun M. Alhamadsheh United States	16	684 0.6×	164 0.5×	70 0.3×	397 1.6×	234 1.6×	28	1.1k
Dirksen E. Bussiere United States	20	1.4k 1.2×	273 0.9×	100 0.4×	75 0.3×	242 1.7×	37	1.7k
Richard L. Cysyk United States	22	977 0.9×	334 1.1×	85 0.3×	56 0.2×	201 1.4×	72	1.5k
John C. Schmitz United States	20	837 0.7×	475 1.5×	52 0.2×	47 0.2×	112 0.8×	59	1.4k
Martin J. Griffin United States	24	889 0.8×	239 0.8×	47 0.2×	38 0.2×	83 0.6×	58	1.6k
Clark A. Sehon United States	14	1.3k 1.2×	213 0.7×	97 0.4×	52 0.2×	626 4.4×	18	2.3k

Countries citing papers authored by Christopher W. Carreras

Since Specialization

Citations

This map shows the geographic impact of Christopher W. Carreras's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher W. Carreras with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher W. Carreras more than expected).

Fields of papers citing papers by Christopher W. Carreras

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher W. Carreras. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher W. Carreras. The network helps show where Christopher W. Carreras may publish in the future.

Co-authorship network of co-authors of Christopher W. Carreras

This figure shows the co-authorship network connecting the top 25 collaborators of Christopher W. Carreras. A scholar is included among the top collaborators of Christopher W. Carreras based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christopher W. Carreras. Christopher W. Carreras is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Henise, Jeff, John A. Hangasky, Deborah H. Charych, et al.. (2024). A platform technology for ultra-long acting intratumoral therapy. Scientific Reports. 14(1). 14000–14000. 4 indexed citations

Fontaine, Shaun D., Christopher W. Carreras, Ralph R. Reid, Gary W. Ashley, & Daniel V. Santi. (2023). A Very Long-acting Exatecan and Its Synergism with DNA Damage Response Inhibitors. Cancer Research Communications. 3(5). 908–916. 2 indexed citations

Jacobs, Jeffrey, Michael R. Leadbetter, Noah Bell, et al.. (2022). Discovery of Tenapanor: A First-in-Class Minimally Systemic Inhibitor of Intestinal Na⁺/H⁺ Exchanger Isoform 3. ACS Medicinal Chemistry Letters. 13(7). 1043–1051. 14 indexed citations

Chen, Tao, Noah Bell, Patricia D. Finn, et al.. (2018). Design of Gut-Restricted Thiazolidine Agonists of G Protein-Coupled Bile Acid Receptor 1 (GPBAR1, TGR5). Journal of Medicinal Chemistry. 61(17). 7589–7613. 28 indexed citations

Labonté, Eric D., Christopher W. Carreras, Michael R. Leadbetter, et al.. (2014). Gastrointestinal Inhibition of Sodium-Hydrogen Exchanger 3 Reduces Phosphorus Absorption and Protects against Vascular Calcification in CKD. Journal of the American Society of Nephrology. 26(5). 1138–1149. 86 indexed citations

Spencer, Andrew, Eric D. Labonté, David P. Rosenbaum, et al.. (2014). Intestinal Inhibition of the Na ⁺ /H ⁺ Exchanger 3 Prevents Cardiorenal Damage in Rats and Inhibits Na ⁺ Uptake in Humans. Science Translational Medicine. 6(227). 227ra36–227ra36. 126 indexed citations

Liu, Yaoquan, et al.. (2011). The role of the 4′′-hydroxyl on motilin agonist potency in the 9-dihydroerythromycin series. Bioorganic & Medicinal Chemistry Letters. 21(12). 3712–3714. 3 indexed citations

Liu, Yaoquan, Yong Li, Yue Chen, et al.. (2010). 9-Dihydroerythromycins as non-antibiotic motilin receptor agonists. Bioorganic & Medicinal Chemistry Letters. 20(19). 5658–5661. 3 indexed citations

Liu, Yaoquan, et al.. (2010). 9-Dihydroerythromycin ethers as motilin agonists—Developing structure–activity relationships for potency and safety. Bioorganic & Medicinal Chemistry. 18(21). 7651–7658. 4 indexed citations

10.

Tian, Zong‐Qiang, Yaoquan Liu, Dan Zhang, et al.. (2004). Synthesis and biological activities of novel 17-aminogeldanamycin derivatives. Bioorganic & Medicinal Chemistry. 12(20). 5317–5329. 128 indexed citations

11.

Carreras, Christopher W., Andreas Schirmer, Ziyang Zhong, & Daniel V. Santi. (2003). Filter binding assay for the geldanamycin–heat shock protein 90 interaction. Analytical Biochemistry. 317(1). 40–46. 26 indexed citations

12.

Revill, W. Peter, Jan Voda, Loleta Chung, et al.. (2002). Genetically Engineered Analogs of Ascomycin for Nerve Regeneration. Journal of Pharmacology and Experimental Therapeutics. 302(3). 1278–1285. 41 indexed citations

13.

Carreras, Christopher W., Michael A. Siani, Daniel V. Santi, & Susan B. Dillon. (2002). Stable Expression of a Synthetic Gene for the Human Motilin Receptor: Use in an Aequorin-Based Receptor Activation Assay. Analytical Biochemistry. 300(2). 146–151. 8 indexed citations

14.

Carreras, Christopher W., et al.. (2001). An FKBP12 Binding Assay Based upon Biotinylated FKBP12. Analytical Biochemistry. 298(1). 57–61. 5 indexed citations

15.

Carreras, Christopher W. & Gary W. Ashley. (2000). Manipulation of polyketide biosynthesis for new drug discovery. Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions. 89. 89–108. 2 indexed citations

16.

Siani, Michael A., A. Geoffrey Skillman, Christopher W. Carreras, et al.. (2000). Development and screening of a polyketide virtual library for drug leads against a motilide pharmacophore. Journal of Molecular Graphics and Modelling. 18(4-5). 497–511. 7 indexed citations

17.

Perry, Kathy M., Christopher W. Carreras, Louise Chang, Daniel V. Santi, & Robert M. Stroud. (1993). Structures of thymidylate synthase with a C-terminal deletion: Role of the C-terminus in alignment of 2'-deoxyuridine 5'-monophosphate and 5,10-methylenetetrahydrofolate. Biochemistry. 32(28). 7116–7125. 47 indexed citations

18.

Santi, Daniel V., et al.. (1993). Interaction of thymidylate synthase with pyridoxal 5'-phosphate as studied by UV/visible difference spectroscopy and molecular modeling. Biochemistry. 32(44). 11819–11824. 13 indexed citations

19.

Climie, Shane, Christopher W. Carreras, & Daniel V. Santi. (1992). Complete replacement set of amino acids at the C-terminus of thymidylate synthase: quantitative structure-activity relationship of mutants of an enzyme. Biochemistry. 31(26). 6032–6038. 27 indexed citations

20.

Carreras, Christopher W., Shane Climie, & Daniel V. Santi. (1992). Thymidylate synthase with a C-terminal deletion catalyzes partial reactions but is unable to catalyze thymidylate formation. Biochemistry. 31(26). 6038–6044. 20 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact