Giulio Rastelli

9.7k total citations · 4 hit papers
142 papers, 7.5k citations indexed

About

Giulio Rastelli is a scholar working on Molecular Biology, Computational Theory and Mathematics and Organic Chemistry. According to data from OpenAlex, Giulio Rastelli has authored 142 papers receiving a total of 7.5k indexed citations (citations by other indexed papers that have themselves been cited), including 89 papers in Molecular Biology, 52 papers in Computational Theory and Mathematics and 33 papers in Organic Chemistry. Recurrent topics in Giulio Rastelli's work include Computational Drug Discovery Methods (52 papers), Aldose Reductase and Taurine (21 papers) and Protein Structure and Dynamics (19 papers). Giulio Rastelli is often cited by papers focused on Computational Drug Discovery Methods (52 papers), Aldose Reductase and Taurine (21 papers) and Protein Structure and Dynamics (19 papers). Giulio Rastelli collaborates with scholars based in Italy, United States and Germany. Giulio Rastelli's co-authors include Luca Pinzi, Andrew Anighoro, Jürgen Bajorath, Miriam Sgobba, Luca Costantino, Gianluca Degliesposti, Alberto Del Río, Daniele Passarella, Michael S. Christodoulou and A Albasini and has published in prestigious journals such as Journal of the American Chemical Society, Nucleic Acids Research and Journal of Biological Chemistry.

In The Last Decade

Giulio Rastelli

140 papers receiving 7.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Molecular Docking: Shifting Paradigms in Drug Discovery

2019 1.4k citations Luca Pinzi, Giulio Rastelli International Journal of Molecular Sciences profile →
Polypharmacology: Challenges and Opportunities in Drug Discovery

2014 821 citations Andrew Anighoro, Jürgen Bajorath et al. profile →
Fast and accurate predictions of binding free energies using MM‐PBSA and MM‐GBSA

2009 651 citations Giulio Rastelli et al. profile →
The 1,2,3-triazole ring as a bioisostere in medicinal chemistry

2017 566 citations Elisa Bonandi, Michael S. Christodoulou et al. Drug Discovery Today profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Giulio Rastelli Italy	36	4.2k	2.1k	2.0k	851	703	142	7.5k
Paul C. Sanschagrin United States	13	4.3k 1.0×	2.0k 0.9×	1.4k 0.7×	728 0.9×	754 1.1×	14	6.9k
Aurélien Grosdidier Switzerland	21	3.6k 0.9×	1.5k 0.7×	1.0k 0.5×	655 0.8×	568 0.8×	23	6.6k
Perry C. Francis United States	8	4.9k 1.2×	2.9k 1.4×	1.7k 0.9×	950 1.1×	810 1.2×	16	7.7k
Gerhard Wolber Germany	42	4.5k 1.1×	2.7k 1.3×	1.8k 0.9×	1.1k 1.3×	744 1.1×	218	8.0k
Stephen R. Johnson United States	24	3.4k 0.8×	2.6k 1.2×	2.8k 1.4×	870 1.0×	798 1.1×	65	7.7k
Jonathan B. Baell Australia	39	5.1k 1.2×	2.2k 1.1×	2.5k 1.3×	929 1.1×	665 0.9×	177	9.2k
Stefano Forli United States	37	6.1k 1.5×	2.6k 1.2×	2.9k 1.5×	963 1.1×	1.1k 1.5×	96	10.7k
Giulio Vistoli Italy	39	4.0k 1.0×	967 0.5×	1.7k 0.9×	626 0.7×	693 1.0×	217	8.2k
Mee Shelley Canada	16	5.5k 1.3×	3.0k 1.4×	2.0k 1.0×	975 1.1×	848 1.2×	37	9.0k
Jasna Klicić United States	6	4.9k 1.2×	3.0k 1.4×	1.9k 1.0×	954 1.1×	825 1.2×	8	7.9k

Countries citing papers authored by Giulio Rastelli

Since Specialization

Citations

This map shows the geographic impact of Giulio Rastelli's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Giulio Rastelli with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Giulio Rastelli more than expected).

Fields of papers citing papers by Giulio Rastelli

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Giulio Rastelli. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Giulio Rastelli. The network helps show where Giulio Rastelli may publish in the future.

Co-authorship network of co-authors of Giulio Rastelli

This figure shows the co-authorship network connecting the top 25 collaborators of Giulio Rastelli. A scholar is included among the top collaborators of Giulio Rastelli based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Giulio Rastelli. Giulio Rastelli is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Facchetti, Giorgio, Valentina Coccè, Luisa Doneda, et al.. (2025). Design, synthesis, and biological evaluation of chalcone derivatives as selective Monoamine Oxidase-B inhibitors with potential neuroprotective effects. European Journal of Medicinal Chemistry. 298. 117990–117990. 2 indexed citations

Pinzi, Luca, et al.. (2024). Early Diagnosis of Neurodegenerative Diseases: What Has Been Undertaken to Promote the Transition from PET to Fluorescence Tracers. Molecules. 29(3). 722–722. 8 indexed citations

Pinzi, Luca, et al.. (2024). Searching for Novel HDAC6/Hsp90 Dual Inhibitors with Anti-Prostate Cancer Activity: In Silico Screening and In Vitro Evaluation. Pharmaceuticals. 17(8). 1072–1072. 2 indexed citations

Moi, Davide, Davide Bonanni, Silvia Belluti, et al.. (2023). Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer. European Journal of Medicinal Chemistry. 260. 115730–115730. 14 indexed citations

Tinivella, Annachiara, Paola Orlandi, Ian R. Baxendale, et al.. (2023). Discovery of a Potent Dual Inhibitor of Aromatase and Aldosterone Synthase. ACS Pharmacology & Translational Science. 6(12). 1870–1883. 3 indexed citations

Pinzi, Luca, et al.. (2023). Identification of Promising Drug Candidates against Prostate Cancer through Computationally-Driven Drug Repurposing. International Journal of Molecular Sciences. 24(4). 3135–3135. 1 indexed citations

Pinzi, Luca, et al.. (2021). LigAdvisor: a versatile and user-friendly web-platform for drug design. Nucleic Acids Research. 49(W1). W326–W335. 13 indexed citations

Iacovino, L.G., Luca Pinzi, Giorgio Facchetti, et al.. (2021). Promising Non-cytotoxic Monosubstituted Chalcones to Target Monoamine Oxidase-B. ACS Medicinal Chemistry Letters. 12(7). 1151–1158. 25 indexed citations

Bonandi, Elisa, Michael S. Christodoulou, Gaia Fumagalli, et al.. (2017). The 1,2,3-triazole ring as a bioisostere in medicinal chemistry. Drug Discovery Today. 22(10). 1572–1581. 566 indexed citations breakdown →

10.

Marabese, Mirko, Elisa Caiola, Marina Chiara Garassino, et al.. (2016). G48A, a New KRAS Mutation Found in Lung Adenocarcinoma. Journal of Thoracic Oncology. 11(7). 1170–1175. 5 indexed citations

11.

Anighoro, Andrew, Dagmar Stumpfe, Kathrin Heikamp, et al.. (2015). Computational Polypharmacology Analysis of the Heat Shock Protein 90 Interactome. Journal of Chemical Information and Modeling. 55(3). 676–686. 17 indexed citations

12.

Rastelli, Giulio & Luca Pinzi. (2015). Computational polypharmacology comes of age. Frontiers in Pharmacology. 6. 157–157. 48 indexed citations

13.

Rastelli, Giulio. (2009). Fragment‐Based Drug Discovery: A Practical Approach. Edited by Edward R. Zartler and Michael J. Shapiro.. ChemMedChem. 4(10). 1756–1757. 36 indexed citations

14.

Rastelli, Giulio, et al.. (2003). Structure of Plasmodium vivax dihydrofolate reductase determined by homology modeling and molecular dynamics refinement. Bioorganic & Medicinal Chemistry Letters. 13(19). 3257–3260. 12 indexed citations

15.

Ghelli, Stefano, Marcella Rinaldi, Daniela Barlocco, et al.. (2003). ortho-Halogen naphthaleins as specific inhibitors of Lactobacillus casei thymidylate synthase. Conformational properties and biological activity. Bioorganic & Medicinal Chemistry. 11(6). 951–963. 8 indexed citations

16.

Pinna, Gérard A., et al.. (2001). Synthesis and cytotoxicity of bis(benzo[g]indole-3-carboxamides) and related compounds. Archiv der Pharmazie. 334(11). 337–337. 6 indexed citations

17.

Costantino, Luca, Giulio Rastelli, Maria Cristina Gamberini, & Daniela Barlocco. (2000). Pharmacological approaches to the treatment of diabetic complications. Expert Opinion on Therapeutic Patents. 10(8). 1245–1262. 73 indexed citations

18.

Costi, Maria Paola, et al.. (1996). Model chemical studies of thymidylate synthase. Nucleophilic addition of hydroxylamine to uracil and 5-fluorouracil. IRIS UNIMORE (University of Modena and Reggio Emilia). 51(3). 209–214. 1 indexed citations

19.

Costantino, Luca, Giulio Rastelli, Teresa Rossi, Michele Corrêa Bertoldi, & A Albasini. (1994). Composition, Superoxide Radicals Scavenging and Antilipoperoxidant Activity of some Edible Fruits. Fitoterapia. 65(1). 44–47. 9 indexed citations

20.

Vampa, G, et al.. (1993). Crystal and Molecular Structures of 5-fluoro-3-methyl-5-chloro-3-methyl- and 5-chloro 1,3-dimethyl-uracil. Hydrogen-bond Patterns through X-Ray and Molecular Orbital Analysis. Journal of Chemical Research Synopses. 6(6). 212–213. 4 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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