Clark A. Sehon

4.1k total citations · 2 hit papers
18 papers, 2.3k citations indexed

About

Clark A. Sehon is a scholar working on Molecular Biology, Immunology and Organic Chemistry. According to data from OpenAlex, Clark A. Sehon has authored 18 papers receiving a total of 2.3k indexed citations (citations by other indexed papers that have themselves been cited), including 10 papers in Molecular Biology, 6 papers in Immunology and 5 papers in Organic Chemistry. Recurrent topics in Clark A. Sehon's work include Immune Response and Inflammation (5 papers), Chemical Synthesis and Analysis (3 papers) and Protease and Inhibitor Mechanisms (3 papers). Clark A. Sehon is often cited by papers focused on Immune Response and Inflammation (5 papers), Chemical Synthesis and Analysis (3 papers) and Protease and Inhibitor Mechanisms (3 papers). Clark A. Sehon collaborates with scholars based in United States, United Kingdom and Belgium. Clark A. Sehon's co-authors include Peter J. Gough, John Bertin, Robert W. Marquis, James A. Marshall, Edward S. Mocarski, Jason W. Upton, William J. Kaiser, Haripriya Sridharan, Chunzi Huang and Pratyusha Mandal and has published in prestigious journals such as Journal of the American Chemical Society, Journal of Biological Chemistry and PLoS ONE.

In The Last Decade

Clark A. Sehon

18 papers receiving 2.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL

2013 747 citations William J. Kaiser, Haripriya Sridharan et al. Journal of Biological Chemistry profile →
MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates

2014 663 citations Yves Dondelinger, Wim Declercq et al. Cell Reports profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Clark A. Sehon United States	14	1.3k	739	626	250	213	18	2.3k
Chengye Yuan China	19	1.6k 1.2×	635 0.9×	701 1.1×	350 1.4×	265 1.2×	76	2.5k
Sara J. Buhrlage United States	26	1.9k 1.4×	429 0.6×	440 0.7×	265 1.1×	717 3.4×	66	2.9k
Wagner B. Dias Brazil	26	1.7k 1.3×	809 1.1×	678 1.1×	298 1.2×	166 0.8×	51	2.3k
Thomas A. Rano United States	12	1.8k 1.4×	419 0.6×	375 0.6×	234 0.9×	365 1.7×	15	2.4k
Jinliang Yang China	29	1.3k 1.0×	276 0.4×	745 1.2×	169 0.7×	566 2.7×	109	2.7k
René Hennig Germany	23	951 0.7×	241 0.3×	237 0.4×	143 0.6×	254 1.2×	60	1.7k
Peter D. Hobbs United States	26	1.8k 1.3×	503 0.7×	382 0.6×	61 0.2×	224 1.1×	61	2.5k
Jason D. Katz United States	12	946 0.7×	994 1.3×	335 0.5×	131 0.5×	213 1.0×	23	1.9k
Santanu Mondal India	24	748 0.6×	947 1.3×	175 0.3×	123 0.5×	205 1.0×	44	2.0k
Martin K. Bijsterbosch Netherlands	25	1.0k 0.8×	452 0.6×	139 0.2×	153 0.6×	225 1.1×	46	1.9k

Countries citing papers authored by Clark A. Sehon

Since Specialization

Citations

This map shows the geographic impact of Clark A. Sehon's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Clark A. Sehon with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Clark A. Sehon more than expected).

Fields of papers citing papers by Clark A. Sehon

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Clark A. Sehon. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Clark A. Sehon. The network helps show where Clark A. Sehon may publish in the future.

Co-authorship network of co-authors of Clark A. Sehon

This figure shows the co-authorship network connecting the top 25 collaborators of Clark A. Sehon. A scholar is included among the top collaborators of Clark A. Sehon based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Clark A. Sehon. Clark A. Sehon is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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18 of 18 papers shown

Rickard, David J., Clark A. Sehon, Viera Kasparcova, et al.. (2014). Identification of Selective Small Molecule Inhibitors of the Nucleotide-Binding Oligomerization Domain 1 (NOD1) Signaling Pathway. PLoS ONE. 9(5). e96737–e96737. 17 indexed citations

Dondelinger, Yves, Wim Declercq, Sylvie Montessuit, et al.. (2014). MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates. Cell Reports. 7(4). 971–981. 663 indexed citations breakdown →

Rickard, David J., Clark A. Sehon, Viera Kasparcova, et al.. (2013). Identification of Benzimidazole Diamides as Selective Inhibitors of the Nucleotide-Binding Oligomerization Domain 2 (NOD2) Signaling Pathway. PLoS ONE. 8(8). e69619–e69619. 44 indexed citations

Kaiser, William J., Haripriya Sridharan, Chunzi Huang, et al.. (2013). Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL. Journal of Biological Chemistry. 288(43). 31268–31279. 747 indexed citations breakdown →

Gatheral, Timothy, Daniel M. Reed, Laura Moreno, et al.. (2012). A Key Role for the Endothelium in NOD1 Mediated Vascular Inflammation: Comparison to TLR4 Responses. PLoS ONE. 7(8). e42386–e42386. 37 indexed citations

Mani, Neelakandha S., Xiaohu Deng, Chennagiri R. Pandit, et al.. (2010). Practical and Scalable Synthesis of a Selective CCK₁ Receptor Antagonist. The Journal of Organic Chemistry. 75(22). 7950–7953. 2 indexed citations

Olzinski, Alan R., Gregory Turner, Roberta E. Bernard, et al.. (2009). Pharmacological Inhibition of C-C Chemokine Receptor 2 Decreases Macrophage Infiltration in the Aortic Root of the Human C-C Chemokine Receptor 2/Apolipoprotein E ^−/− Mouse: Magnetic Resonance Imaging Assessment. Arteriosclerosis Thrombosis and Vascular Biology. 30(2). 253–259. 36 indexed citations

Hilfiker, Mark A., Daohua Zhang, Sarah E. Dowdell, et al.. (2008). Aminomethylpiperazines as selective urotensin antagonists. Bioorganic & Medicinal Chemistry Letters. 18(16). 4470–4473. 13 indexed citations

Sehon, Clark A., Andrew Q. Viet, Krista Goodman, et al.. (2008). Potent, Selective and Orally Bioavailable Dihydropyrimidine Inhibitors of Rho Kinase (ROCK1) as Potential Therapeutic Agents for Cardiovascular Diseases. Journal of Medicinal Chemistry. 51(21). 6631–6634. 63 indexed citations

10.

Gomez, Laurent, Michael D. Hack, Kelly J. McClure, et al.. (2007). SAR studies of 1,5-diarylpyrazole-based CCK1 receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 17(23). 6493–6498. 13 indexed citations

11.

Grice, Cheryl A., Haripada Khatuya, Darin J. Gustin, et al.. (2006). The SAR of 4-substituted (6,6-bicyclic) piperidine cathepsin S inhibitors. Bioorganic & Medicinal Chemistry Letters. 16(8). 2209–2212. 10 indexed citations

12.

Sehon, Clark A., Kelly J. McClure, Michael D. Hack, et al.. (2005). Pyrazole CCK1 receptor antagonists. Part 2: SAR studies by solid-phase library synthesis and determination of Free–Wilson additivity. Bioorganic & Medicinal Chemistry Letters. 16(1). 77–80. 19 indexed citations

13.

McClure, Kelly J., Michael D. Hack, Clark A. Sehon, et al.. (2005). Pyrazole CCK1 receptor antagonists. Part 1: Solution-phase library synthesis and determination of Free–Wilson additivity. Bioorganic & Medicinal Chemistry Letters. 16(1). 72–76. 20 indexed citations

14.

Gustin, Darin J., Clark A. Sehon, Jianmei Wei, et al.. (2005). Discovery and SAR studies of a novel series of noncovalent cathepsin S inhibitors. Bioorganic & Medicinal Chemistry Letters. 15(6). 1687–1691. 32 indexed citations

15.

Thurmond, Robin L., Siquan Sun, Clark A. Sehon, et al.. (2004). Identification of a Potent and Selective Noncovalent Cathepsin S Inhibitor. Journal of Pharmacology and Experimental Therapeutics. 308(1). 268–276. 44 indexed citations

16.

Boger, Dale L., Christopher W. Boyce, Marc Labroli, Clark A. Sehon, & Qing Jin. (1998). Total Syntheses of Ningalin A, Lamellarin O, Lukianol A, and Permethyl Storniamide A Utilizing Heterocyclic Azadiene Diels−Alder Reactions. Journal of the American Chemical Society. 121(1). 54–62. 350 indexed citations

17.

Marshall, James A. & Clark A. Sehon. (1997). Total Synthesis of the Enantiomer of the Furanocembrane Rubifolide. The Journal of Organic Chemistry. 62(13). 4313–4320. 51 indexed citations

18.

Marshall, James A. & Clark A. Sehon. (1995). Synthesis of Furans and 2,5-Dihydrofurans by Ag(I)-Catalyzed Isomerization of Allenones, Alkynyl Allylic Alcohols, and Allenylcarbinols. The Journal of Organic Chemistry. 60(18). 5966–5968. 151 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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