John C. Schmitz

1.8k citations

59 papers · 1.4k indexed · h-index 20

Impact in

Oncology top 5%
- Colorectal Cancer Treatments and Studies
- Cancer-related Molecular Pathways
Molecular Biology top 10%
- Biochemical and Molecular Research
- RNA modifications and cancer
- Epigenetics and DNA Methylation
- ATP Synthase and ATPases Research

Papers in

Oncology 33
- Cancer-related Molecular Pathways 12
- Colorectal Cancer Treatments and Studies 10
Molecular Biology 42
- Biochemical and Molecular Research 9
- RNA modifications and cancer 8
- DNA Repair Mechanisms 6
- RNA Research and Splicing 6
- RNA Interference and Gene Delivery 5

Co-authors: Edward Chu Michael Farrell David G. Priest Michal G. Rose Peter Wipf Ning Wei Robert K. Stuart Marlene A. Bunni
Journals: Cancer Chemotherapy and Pharmacology (5 papers)Oncotarget (3 papers)Cancer Research (3 papers)Biochemical Pharmacology (3 papers)Clinical Cancer Research (2 papers)
Partner nations: United States China Greece

In The Last Decade

John C. Schmitz

57 papers receiving 1.4k citations

Peers

Countries citing papers authored by John C. Schmitz

Since Specialization

Citations

This map shows the geographic impact of John C. Schmitz's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John C. Schmitz with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John C. Schmitz more than expected).

Fields of papers citing papers by John C. Schmitz

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John C. Schmitz. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John C. Schmitz. The network helps show where John C. Schmitz may publish in the future.

Co-authors

The 25 scholars most cited alongside John C. Schmitz, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John C. Schmitz Line = papers co-authored together John C. Schmitz links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Phase I trial of ATR inhibitor elimusertib with FOLFIRI in advanced or metastatic gastrointestinal malignancies (ETCTN 10406) Cancer Chemotherapy and Pharmacology ·Anuradha Krishnamurthy, Hong Wang, John C. Rhee, Diwakar Davar, Ryan H. Moy, Lee Ratner, Susan M. Christner, Julianne L. Holleran, Tsitsi Zinyengere, 今田良一, John C. Schmitz, Louis Ngai Yuan Wong, Edward Chu, Christopher J. Bakkenist, Jan H. Beumer, Liza C. Villaruz	2025	4
2	Polo-like Kinase 1 Inhibitors Demonstrate In Vitro and In Vivo Efficacy in Preclinical Models of Small Cell Lung Cancer Cancers ·О Б Зайцева, H. Bauer, Andrei A. Ivanov, Jeffrey M. Switchenko, Shi‐Yong Sun, Gabriel Sica, Titis Wening Setyoharsih, Yufei Huang, John C. Schmitz, Taofeek K. Owonikoko	2025	1
3	Structure–Activity Relationship Study of Splicing Modulators on Hsh155/SF3B1 through Chemical Synthesis and Yeast Genetics ACS Medicinal Chemistry Letters ·В. И. ГОЛОБОРОДЬКО, Aaron Judd, John C. Schmitz, Aaron A. Hoskins, Kazunori Koide	2024	0
4	Quassinoid analogs exert potent antitumor activity via reversible protein biosynthesis inhibition in human colorectal cancer Biochemical Pharmacology ·Ning Wei, James C. Burnett, K Konkarikoski, Yixian Huang, Song Li, Peter Wipf, Edward Chu, John C. Schmitz	2023	6
5	Scutellaria baicalensis enhances 5-fluorouracil-based chemotherapy via inhibition of proliferative signaling pathways Cell Communication and Signaling ·Haizhou Liu, Hui Liu, Zhiyi Zhou, Jessica Chung, О Б Зайцева, Howard F. Browning, Robert A. Parise, Edward Chu, John C. Schmitz	2023	8
6	Phase 1 study of safety, pharmacokinetics, and pharmacodynamics of tivantinib in combination with bevacizumab in adult patients with advanced solid tumors Cancer Chemotherapy and Pharmacology ·William F. Maguire, John C. Schmitz, M.D. Pistun, NENONENE Yawo Amen, Mahmoud El‐Gamal, Sun Zhen-don, Shaoyu Wu, Lin Huang, Shannon Puhalla, John C. Rhee, Ronald G. Stoller, Hussein A. Tawbi, James J. Lee, James R. Wright, Jan H. Beumer, Edward Chu, Leonard J. Appleman, (unknown)	2021	4
7	Molecular subtypes of colorectal cancer in pre-clinical models show differential response to targeted therapies: Treatment implications beyond KRAS mutations PLoS ONE ·Rekha Pal, Ning Wei, Nan Song, Shaoyu Wu, Rim S. Kim, Ying Wang, Patrick G. Gavin, Peter C. Lucas, Ashok Srinivasan, Carmen J. Allegra, Samuel A. Jacobs, Soonmyung Paik, John C. Schmitz, Katherine L. Pogue–Geile	2018	8
8	ATM Is Required for the Repair of Oxaliplatin-Induced DNA Damage in Colorectal Cancer Clinical Colorectal Cancer ·Christopher J. Bakkenist, James J. Lee, John C. Schmitz	2018	14
9	Protein Kinase D as a Potential Chemotherapeutic Target for Colorectal Cancer Molecular Cancer Therapeutics ·Ning Wei, Edward Chu, Peter Wipf, John C. Schmitz	2014	54
10	Development of modified siRNA molecules incorporating 5-fluoro-2'-deoxyuridine residues to enhance cytotoxicity Nucleic Acids Research ·Rosemary C. Leone, Ivan Andreev, William H. Gmeiner, Edward Chu, John C. Schmitz	2013	14
11	Intermedin is overexpressed in hepatocellular carcinoma and regulates cell proliferation and survival Cancer Science ·Xiaojia Guo, John C. Schmitz, Barton Kenney, Edward Uchio, Sanjay Kulkarni, Charles Cha	2012	19
12	Effect of small interfering RNA 3'-end overhangs on chemosensitivity to thymidylate synthase inhibitors PubMed ·John C. Schmitz, Edward Chu	2011	18
13	The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer Laboratory Investigation ·Chuhan Chung, Christopher C. Mader, John C. Schmitz, 力图霍, D. K. Johnston, Mona Cornwell, Anthony J. Koleske, Susan E. Crawford, Fred S. Gorelick	2011	88
14	C-Raf Is Associated with Disease Progression and Cell Proliferation in a Subset of Melanomas Clinical Cancer Research ·Lucia B. Jilaveanu, Christopher R. Zito, Saadia A. Aziz, Patricia J. Conrad, John C. Schmitz, Mario Sznol, Robert L. Camp, David L. Rimm, Harriet M. Kluger	2009	34
15	Multi-level gene expression profiles affected by thymidylate synthase and 5-fluorouracil in colon cancer BMC Genomics ·Yaguang Xi, Go Nakajima, John C. Schmitz, Edward Chu, Jingfang Ju	2006	33
16	Thymidylate synthase as a translational regulator of cellular gene expression Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ·Jun Liu, John C. Schmitz, Xiukun Lin, Ningwen Tai, Yan Wu, Michael Farrell, Agisti Amelia, Ivan Andreev, Edward Chu	2002	100
17	Thymidylate Synthase: A Critical Target for Cancer Chemotherapy Clinical Colorectal Cancer ·Michal G. Rose, Michael Farrell, John C. Schmitz	2002	117
18	Impact of schedule on leucovorin potentiation of fluorouracil antitumor activity in dietary folic acid deplete mice Biochemical Pharmacology ·Lei Zhang, John C. Schmitz, David G. Priest	1997	18
19	Impact of dietary folic acid on reduced folates in mouse plasma and tissues Biochemical Pharmacology ·John C. Schmitz, 柳田勝男, Richard M. Schultz, David G. Priest	1994	43
20	Folate Metabolites as Modulators of Antitumor Drug Activity Advances in experimental medicine and biology ·David G. Priest, John C. Schmitz, Marlene A. Bunni	1993	7

About John C. Schmitz

John C. Schmitz is a scholar working on Oncology, Molecular Biology, Cancer Research, Toxicology and Hepatology, having authored 59 papers that have together received 1.4k indexed citations. Recurring topics across this work include Cancer-related Molecular Pathways (12 papers), Colorectal Cancer Treatments and Studies (10 papers), Biochemical and Molecular Research (9 papers), RNA modifications and cancer (8 papers), Folate and B Vitamins Research (7 papers), DNA Repair Mechanisms (6 papers), RNA Research and Splicing (6 papers) and RNA Interference and Gene Delivery (5 papers). The work is most often cited by research in Oncology (475 citations), Molecular Biology (837 citations), Cancer Research (180 citations), Rheumatology (173 citations) and Toxicology (25 citations). John C. Schmitz has collaborated with scholars based in United States, China and Greece. Frequent co-authors include Edward Chu, Michael Farrell, David G. Priest, Michal G. Rose, Peter Wipf, Ning Wei, Robert K. Stuart, Marlene A. Bunni, Xiukun Lin and Ningwen Tai. Their work appears in journals such as Cancer Chemotherapy and Pharmacology, Oncotarget, Cancer Research, Biochemical Pharmacology and Clinical Cancer Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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