Chih‐Hao Lee

7.9k citations

44 papers · 4.8k indexed · 3 hit papers · h-index 28

Impact in

Biochemistry top 0.5%
Endocrine and Autonomic Systems top 2%
- Circadian rhythm and melatonin

Papers in

Physiology 17
- Adipose Tissue and Metabolism 9
- Diet and metabolism studies 4
Neurology 5
- Neuroinflammation and Neurodegeneration Mechanisms 5

Co-authors: Sihao Liu Ronald M. Evans Ajay Chawla Linda K. Curtiss Sean B. Joseph Bryan Laffitte Yaacov Barak Peter Tontonoz
Journals: Journal of Biological Chemistry (3 papers)The FASEB Journal (3 papers)Cell Metabolism (2 papers)Proceedings of the National Academy of Sciences (2 papers)Nature Medicine (1 paper)
Partner nations: United States China Taiwan

In The Last Decade

Chih‐Hao Lee

43 papers receiving 4.8k citations

Hit Papers

align trajectories log scale

Akt Stimulates Hepatic SREBP1c and Lipogenesis through Parallel mTORC1-Dependent and Independent Pathways 2011 · 514 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2011 Cell Metabolism
2010 Proceedings of the National Academy of Sciences
2001 Molecular Cell

Peers

Countries citing papers authored by Chih‐Hao Lee

Since Specialization

Citations

This map shows the geographic impact of Chih‐Hao Lee's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Chih‐Hao Lee with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Chih‐Hao Lee more than expected).

Fields of papers citing papers by Chih‐Hao Lee

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Chih‐Hao Lee. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Chih‐Hao Lee. The network helps show where Chih‐Hao Lee may publish in the future.

Co-authors

The 25 scholars most cited alongside Chih‐Hao Lee, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Chih‐Hao Lee Line = papers co-authored together Chih‐Hao Lee links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Fructose induces inflammatory activation in macrophages and microglia through the nutrient‐sensing ghrelin receptor The FASEB Journal ·Zheng Shen, Zeyu Liu, Hongying Wang, Danilo Landrock, Ji Yeon Noh, Qun S. Zang, Chih‐Hao Lee, Yuhua Z. Farnell, Zheng Chen, Yuxiang Sun	2025	2
2	Discovery and validation of plasma, saliva and multi-fluid plasma–saliva metabolomic scores predicting insulin resistance and diabetes progression or regression among Puerto Rican adults Diabetologia ·Danielle E. Haslam, Liming Liang, Kai Guo, Marijulie Martínez-Lozano, Cynthia M. Pérez, Chih‐Hao Lee, Evangelia Morou-Bermúdez, Clary B. Clish, David T. Wong, JoAnn E. Manson, Frank B. Hu, Meir J. Stampfer, Kaumudi Joshipura, Shilpa N Bhupathiraju	2024	3
3	Hepatic Fis1 regulates mitochondrial integrated stress response and improves metabolic homeostasis JCI Insight ·Yae-Huei Liou, Jean Personnaz, David Jacobi, Nelson H. Knudsen, Mayer M. Chalom, Kyle A. Starost, Israel C. Nnah, Chih‐Hao Lee	2022	17
4	Associations of network-derived metabolite clusters with prevalent type 2 diabetes among adults of Puerto Rican descent BMJ Open Diabetes Research & Care ·Danielle E. Haslam, Liming Liang, Dong D. Wang, Rachel S. Kelly, Clemens Wittenbecher, Cynthia M. Pérez, M Olmo Martinez, Chih‐Hao Lee, Clary B. Clish, David T. Wong, Laurence D. Parnell, Chao‐Qiang Lai, José M. Ordovás, JoAnn E. Manson, Frank B. Hu, Meir J. Stampfer, Katherine L. Tucker, Kaumudi Joshipura, Shilpa N Bhupathiraju	2021	6
5	Changes in metabolomics profiles over ten years and subsequent risk of developing type 2 diabetes: Results from the Nurses' Health Study EBioMedicine ·Clemens Wittenbecher, Marta Guasch‐Ferré, Danielle E. Haslam, Courtney Dennis, Jun Li, Shilpa N Bhupathiraju, Chih‐Hao Lee, Qibin Qi, Liming Liang, A. Heather Eliassen, Clary B. Clish, Qi Sun, Frank B. Hu	2021	25
6	Lipid Profiles and Heart Failure Risk Circulation Research ·Clemens Wittenbecher, Fabian Eichelmann, Estefanía Toledo, Marta Guasch‐Ferré, Miguel Ruiz‐Canela, Jun Li, Fernando Arós, Chih‐Hao Lee, Liming Liang, Jordi Salas‐Salvadó, Clary B. Clish, Matthias B. Schulze, Miguel Ángel Martínez‐González, Frank B. Hu	2020	66
7	FAM13A Represses AMPK Activity and Regulates Hepatic Glucose and Lipid Metabolism iScience ·Xin Lin, Yae-Huei Liou, Yujun Li, Lu Gong, Yan Li, Yuan Hao, Betty Pham, Shuang Xu, Zhiqiang Jiang, Lijia Li, Yifan Peng, Dandi Qiao, Honghuang Lin, Pengda Liu, Wenyi Wei, Guo Zhang, Chih‐Hao Lee, Xiaobo Zhou	2020	15
8	Inflammation-induced iron transport and metabolism by brain microglia Journal of Biological Chemistry ·Ryan C. McCarthy, Jose Carlo Sosa, Andrew M. Gardeck, Andrew Baez, Chih‐Hao Lee, Marianne Wessling‐Resnick	2018	137
9	Macrophage alternative activation confers protection against lipotoxicity-induced cell death Molecular Metabolism ·Lingling Dai, Prerna Bhargava, Kristopher J. Stanya, Ryan Alexander, Yae-Huei Liou, David Jacobi, Nelson H. Knudsen, Alexander L. Hyde, Matthew R. Gangl, Sihao Liu, Chih‐Hao Lee	2017	25
10	Genetic Control of Fatty Acid β-Oxidation in Chronic Obstructive Pulmonary Disease American Journal of Respiratory Cell and Molecular Biology ·Zhiqiang Jiang, Nelson H. Knudsen, Gang Wang, Weiliang Qiu, Zun Zar Chi Naing, Yan Bai, Xingbin Ai, Chih‐Hao Lee, Xiaobo Zhou	2017	59
11	Protective Effects of the Mediterranean Diet on Type 2 Diabetes and Metabolic Syndrome Journal of Nutrition ·Jordi Salas‐Salvadó, Marta Guasch‐Ferré, Chih‐Hao Lee, Ramón Estruch, Clary B. Clish, Emilio Ros	2016	163
12	Characterization of a novel adult murine immortalized microglial cell line and its activation by amyloid-beta Journal of Neuroinflammation ·Ryan C. McCarthy, Dah‐Yuu Lu, Ahmed Alkhateeb, Andrew M. Gardeck, Chih‐Hao Lee, Marianne Wessling‐Resnick	2016	55
13	Antineuroinflammatory effects of lycopene via activation of adenosine monophosphate-activated protein kinase-α1/heme oxygenase-1 pathways Neurobiology of Aging ·Hsiao-Yun Lin, Bor-Ren Huang, Wei-Lan Yeh, Chih‐Hao Lee, Shiang-Suo Huang, Chih‐Ho Lai, Ho Lin, Dah-Yuu Lu	2013	92
14	Host Metabolism Regulates Intracellular Growth of Trypanosoma cruzi Cell Host & Microbe ·Kacey L. Caradonna, Juan C. Engel, David Jacobi, Chih‐Hao Lee, Barbara A. Burleigh	2013	101
15	Adipose tissue signaling by nuclear receptors in metabolic complications of obesity Adipocyte ·David Jacobi, Kristopher J. Stanya, Chih‐Hao Lee	2012	37
16	Immunomodulatory glycan LNFPIII alleviates hepatosteatosis and insulin resistance through direct and indirect control of metabolic pathways Nature Medicine ·Prerna Bhargava, Changlin Li, Kristopher J. Stanya, David Jacobi, Lingling Dai, Sihao Liu, Matthew R. Gangl, Donald A. Harn, Chih‐Hao Lee	2012	109
17	Activation of Natural Killer T Cells Promotes M2 Macrophage Polarization in Adipose Tissue and Improves Systemic Glucose Tolerance via Interleukin-4 (IL-4)/STAT6 Protein Signaling Axis in Obesity Journal of Biological Chemistry ·Yewei Ji, Shengyi Sun, Aimin Xu, Prerna Bhargava, Liu Yang, Karen S.L. Lam, Bin Gao, Chih‐Hao Lee, Sander Kersten, Ling Qi	2012	172
18	Resolvin D1 binds human phagocytes with evidence for proresolving receptors Proceedings of the National Academy of Sciences ·Sriram Krishnamoorthy, Antonio Recchiuti, Nan Chiang, Stephanie Yacoubian, Chih‐Hao Lee, Rong Yang, Nicos A. Petasis, Charles N. Serhan Hit paper breakdown →	2010	589
19	Mechanisms of the Mouse Orphan Nuclear Receptor TR2-11-mediated Gene Suppression Journal of Biological Chemistry ·Chatchai Chinpaisal, Chih‐Hao Lee, Li‐Na Wei	1998	23
20	Pharmacological characterization of RS 25259‐197, a novel and selective 5‐HT₃ receptor antagonist, in vivo British Journal of Pharmacology ·Richard M. Eglen, Chih‐Hao Lee, William L. Smith, L.G. Johnson, Robin D. Clark, R.L. Whiting, Satisha Hegde	1995	51

About Chih‐Hao Lee

Chih‐Hao Lee is a scholar working on Physiology, Neurology, Aging, Endocrine and Autonomic Systems and Biological Psychiatry, having authored 44 papers that have together received 4.8k indexed citations. Recurring topics across this work include Adipose Tissue and Metabolism (9 papers), Peroxisome Proliferator-Activated Receptors (7 papers), Adipokines, Inflammation, and Metabolic Diseases (6 papers), Neuroinflammation and Neurodegeneration Mechanisms (5 papers), Immune Cell Function and Interaction (4 papers), Diet and metabolism studies (4 papers), Diet, Metabolism, and Disease (4 papers) and Metabolomics and Mass Spectrometry Studies (4 papers). The work is most often cited by research in Biochemistry (477 citations), Endocrine and Autonomic Systems (393 citations), Aging (101 citations), Physiology (1.1k citations) and Immunology (866 citations). Chih‐Hao Lee has collaborated with scholars based in United States, China and Taiwan. Frequent co-authors include Sihao Liu, Ronald M. Evans, Ajay Chawla, Linda K. Curtiss, Sean B. Joseph, Bryan Laffitte, Yaacov Barak, Peter Tontonoz, Peter A. Edwards and László Nagy. Their work appears in journals such as Journal of Biological Chemistry, The FASEB Journal, Cell Metabolism, Proceedings of the National Academy of Sciences and Nature Medicine.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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