Sean B. Joseph

13.2k total citations · 7 hit papers
46 papers, 9.5k citations indexed

About

Sean B. Joseph is a scholar working on Molecular Biology, Surgery and Immunology. According to data from OpenAlex, Sean B. Joseph has authored 46 papers receiving a total of 9.5k indexed citations (citations by other indexed papers that have themselves been cited), including 26 papers in Molecular Biology, 19 papers in Surgery and 12 papers in Immunology. Recurrent topics in Sean B. Joseph's work include Cholesterol and Lipid Metabolism (17 papers), Peroxisome Proliferator-Activated Receptors (14 papers) and Monoclonal and Polyclonal Antibodies Research (7 papers). Sean B. Joseph is often cited by papers focused on Cholesterol and Lipid Metabolism (17 papers), Peroxisome Proliferator-Activated Receptors (14 papers) and Monoclonal and Polyclonal Antibodies Research (7 papers). Sean B. Joseph collaborates with scholars based in United States, United Kingdom and France. Sean B. Joseph's co-authors include Peter Tontonoz, Bryan Laffitte, David J. Mangelsdorf, Antonio Castrillo, Peter A. Edwards, Damien C. Wilpitz, Jon L. Collins, Puiying A. Mak, Robert Walczak and Liming Pei and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Sean B. Joseph

45 papers receiving 9.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A PPARγ-LXR-ABCA1 Pathway in Macrophages Is Involved in Cholesterol Efflux and Atherogenesis

2001 1.2k citations Bryan Laffitte, Sean B. Joseph et al. Molecular Cell profile →
Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

2003 981 citations Sean B. Joseph, Antonio Castrillo et al. profile →
Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXRα

2000 836 citations Bryan Laffitte, Sean B. Joseph et al. Proceedings of the National Academy of Sciences profile →
Synthetic LXR ligand inhibits the development of atherosclerosis in mice

2002 778 citations Sean B. Joseph, Liming Pei et al. Proceedings of the National Academy of Sciences profile →
Direct and Indirect Mechanisms for Regulation of Fatty Acid Synthase Gene Expression by Liver X Receptors

2002 631 citations Sean B. Joseph, Bryan Laffitte et al. Journal of Biological Chemistry profile →
LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

2001 560 citations Bryan Laffitte, Sean B. Joseph et al. Proceedings of the National Academy of Sciences profile →
LXR Signaling Couples Sterol Metabolism to Proliferation in the Acquired Immune Response

2008 555 citations Steven J. Bensinger, Michelle N. Bradley et al. Cell profile →

Peers

Countries citing papers authored by Sean B. Joseph

Since Specialization

Citations

This map shows the geographic impact of Sean B. Joseph's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sean B. Joseph with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sean B. Joseph more than expected).

Fields of papers citing papers by Sean B. Joseph

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sean B. Joseph. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sean B. Joseph. The network helps show where Sean B. Joseph may publish in the future.

Co-authorship network of co-authors of Sean B. Joseph

This figure shows the co-authorship network connecting the top 25 collaborators of Sean B. Joseph. A scholar is included among the top collaborators of Sean B. Joseph based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sean B. Joseph. Sean B. Joseph is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Pharmacological expansion of type 2 alveolar epithelial cells promotes regenerative lower airway repair 2024 ·Proceedings of the National Academy of Sciences ·Sida Shao, Nan Zhang, (unknown), (unknown), (unknown), Qiangwei Fu, David Huang, (unknown), Jian Shu, Alain Domissy, Shuangwei Li, Vân Nguyên-Trân, Sean B. Joseph, Arnab K. Chatterjee, (unknown), Peter G. Schultz, Michael J. Bollong	10
2	A small molecule UPR modulator for diabetes identified by high throughput screening 2021 ·Acta Pharmaceutica Sinica B ·(unknown), Tuan Anh Tran, Siying Zhu, Seung‐Hyuk Choi, Ana M. Gamo, Sijia Li, Qiangwei Fu, (unknown), Jason Roland, Mitchell Hull, Vân Nguyên-Trân, Sean B. Joseph, Arnab K. Chatterjee, Nikki Lynn Rogers, Matthew S. Tremblay, Weijun Shen	11
3	Engineering of a Potent, Long-Acting NPY2R Agonist for Combination with a GLP-1R Agonist as a Multi-Hormonal Treatment for Obesity 2020 ·Journal of Medicinal Chemistry ·(unknown), (unknown), (unknown), David Huang, (unknown), Vân Nguyên-Trân, Sean B. Joseph, Shane Roller, Scott Peterson, (unknown), Matthew S. Tremblay, Peter G. Schultz, Weijun Shen	19
4	Design of a Long-Acting and Selective MEG-Fatty Acid Stapled Prolactin-Releasing Peptide Analog 2019 ·ACS Medicinal Chemistry Letters ·(unknown), (unknown), (unknown), Shan Yu, Huafei Zou, (unknown), Sean B. Joseph, Vân Nguyên-Trân, Matthew S. Tremblay, Weijun Shen	12
5	Engineering a Potent, Long-Acting, and Periphery-Restricted Oxytocin Receptor Agonist with Anorexigenic and Body Weight Reducing Effects 2019 ·Journal of Medicinal Chemistry ·(unknown), (unknown), (unknown), Qiangwei Fu, (unknown), (unknown), Sean B. Joseph, Vân Nguyên-Trân, Weijun Shen	7
6	The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis 2018 ·Proceedings of the National Academy of Sciences ·Jeff Janes, (unknown), Emily Chen, Nicole H. Rogers, Sebastian Burgstaller-Muehlbacher, Laura D. Hughes, Melissa S. Love, Mitchell Hull, Kelli Kuhen, Ashley K. Woods, Sean B. Joseph, H. Michael Petrassi, Case W. McNamara, Matthew S. Tremblay, Andrew I. Su, Peter G. Schultz, Arnab K. Chatterjee	125
7	Relative Target Affinities of T-Cell–Dependent Bispecific Antibodies Determine Biodistribution in a Solid Tumor Mouse Model 2018 ·Molecular Cancer Therapeutics ·Danielle Mandikian, (unknown), (unknown), Ji Li, Jeffrey Eastham‐Anderson, Dionysos Slaga, Jason Ho, Maria Hristopoulos, Robyn Clark, Klára Tótpál, Kedan Lin, Sean B. Joseph, Mark S. Dennis, Saileta Prabhu, Teemu T. Junttila, C. Andrew Boswell	112
8	Mathematical PKPD and safety model of bispecific TfR/BACE1 antibodies for the optimization of antibody uptake in brain 2016 ·European Journal of Pharmaceutics and Biopharmaceutics ·Kapil Gadkar, Daniela Bumbaca Yadav, (unknown), Jessica A. Couch, Jitendra Kanodia, Margaret Kenrick, Jasvinder K. Atwal, Mark S. Dennis, Saileta Prabhu, Ryan J. Watts, Sean B. Joseph, Saroja Ramanujan	40
9	Evaluating the Use of Antibody Variable Region (Fv) Charge as a Risk Assessment Tool for Predicting Typical Cynomolgus Monkey Pharmacokinetics 2015 ·Journal of Biological Chemistry ·Daniela Bumbaca Yadav, Vikas Sharma, C. Andrew Boswell, Isidro Hötzel, Devin B. Tesar, Yonglei Shang, Yong Ying, Saloumeh K Fischer, Jane L. Grogan, Eugene Y. Chiang, (unknown), Sheila Ulufatu, Leslie A. Khawli, Saileta Prabhu, Sean B. Joseph, Robert F. Kelley	63
10	Discovery of structurally novel, potent and orally efficacious GPR119 agonists 2014 ·Bioorganic & Medicinal Chemistry Letters ·Phil B. Alper, Mihai Azimioara, (unknown), Daniel Mutnick, V. I. Nikulin, Pierre‐Yves Michellys, Zhiliang Wang, (unknown), (unknown), Jing Li, Dingjiu Bao, Jocelyn Zoll, Young Kim, Matthew C. Zimmerman, (unknown), Tove Tuntland, Sean B. Joseph, Peter McNamara, H. Martin Seidel, Robert Epple	9
11	LXR Signaling Couples Sterol Metabolism to Proliferation in the Acquired Immune Response breakdown → 2008 ·Cell ·Steven J. Bensinger, Michelle N. Bradley, Sean B. Joseph, Noam Zelcer, Edith M. Janssen, Mary Ann Hausner, Roger Shih, John S. Parks, Peter A. Edwards, Beth D. Jamieson, Peter Tontonoz	555
12	Comparative bioavailability of a novel timed release and powder-filled glucosamine sulfate formulation a multi-dose, randomized, crossover study 2004 ·International Journal of Clinical Pharmacology and Therapeutics ·(unknown), Sean B. Joseph, (unknown), Sharada Sawant	4
13	LXR-Dependent Gene Expression Is Important for Macrophage Survival and the Innate Immune Response 2004 ·Cell ·Sean B. Joseph, Michelle N. Bradley, Antonio Castrillo, Kevin W. Bruhn, Puiying A. Mak, Liming Pei, John B. Hogenesch, Ryan M. O’Connell, Genhong Cheng, Enrique Sáez, Jeffery F. Miller, Peter Tontonoz	473
14	Liver X Receptor-dependent Repression of Matrix Metalloproteinase-9 Expression in Macrophages 2003 ·Journal of Biological Chemistry ·Antonio Castrillo, Sean B. Joseph, Chaitra Marathe, David J. Mangelsdorf, Peter Tontonoz	277
15	Crosstalk between LXR and Toll-like Receptor Signaling Mediates Bacterial and Viral Antagonism of Cholesterol Metabolism 2003 ·Molecular Cell ·Antonio Castrillo, Sean B. Joseph, Sagar A. Vaidya, M E Haberland, Alan M. Fogelman, Genhong Cheng, Peter Tontonoz	396
16	LXRs: new therapeutic targets in atherosclerosis? 2003 ·Current Opinion in Pharmacology ·Sean B. Joseph	84
17	Regulated Expression of the Apolipoprotein E/C-I/C-IV/C-II Gene Cluster in Murine and Human Macrophages 2002 ·Journal of Biological Chemistry ·Puiying A. Mak, Bryan Laffitte, Catherine Desrumaux, Sean B. Joseph, Linda K. Curtiss, David J. Mangelsdorf, Peter Tontonoz, Peter A. Edwards	196
18	Peroxisome Proliferator-activated Receptor α (PPARα) Influences Substrate Utilization for Hepatic Glucose Production 2002 ·Journal of Biological Chemistry ·Jun Xu, Gary Guishan Xiao, (unknown), Vicky C. Chang, (unknown), Sean B. Joseph, Sara Bassilian, Mohammed Saad, Peter Tontonoz, (unknown), Irwin J. Kurland	138
19	Direct and Indirect Mechanisms for Regulation of Fatty Acid Synthase Gene Expression by Liver X Receptors breakdown → 2002 ·Journal of Biological Chemistry ·Sean B. Joseph, Bryan Laffitte, Parthive H. Patel, Michael A. Watson, Karen Matsukuma, Robert Walczak, Jon L. Collins, Timothy F. Osborne, Peter Tontonoz	631
20	Surface Expression of HLA-C Antigen by Human Extravillous Trophoblast 2000 ·Placenta ·Ashley King, Tanya D. Burrows, S.E. Hiby, Joanne M. Bowen, Sean B. Joseph, Sanjay Verma, (unknown), Lucy Gardner, Philippe Le Bouteiller, Andreas Ziegler, (unknown), Y.W. Loke	215

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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