Che‐Kun James Shen

1.8k total citations · 1 hit paper
16 papers, 1.5k citations indexed

About

Che‐Kun James Shen is a scholar working on Molecular Biology, Genetics and Neurology. According to data from OpenAlex, Che‐Kun James Shen has authored 16 papers receiving a total of 1.5k indexed citations (citations by other indexed papers that have themselves been cited), including 11 papers in Molecular Biology, 5 papers in Genetics and 3 papers in Neurology. Recurrent topics in Che‐Kun James Shen's work include Hemoglobinopathies and Related Disorders (4 papers), Epigenetics and DNA Methylation (3 papers) and Amyotrophic Lateral Sclerosis Research (3 papers). Che‐Kun James Shen is often cited by papers focused on Hemoglobinopathies and Related Disorders (4 papers), Epigenetics and DNA Methylation (3 papers) and Amyotrophic Lateral Sclerosis Research (3 papers). Che‐Kun James Shen collaborates with scholars based in Taiwan, United States and India. Che‐Kun James Shen's co-authors include Tom Maniatis, John E. Hearst, Kuen‐Jer Tsai, I‐Fang Wang, Stephen T. Isaacs, Henry Rapoport, Carl V. Hanson, Cheng‐Chun Wu, Yu‐Chih Liu and Chun‐Hung Yang and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Che‐Kun James Shen

16 papers receiving 1.3k citations

Hit Papers

The chromosomal arrangement of human α-like globin genes:... 1980 2026 1995 2010 1980 100 200 300 400
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. The chromosomal arrangement of human α-like globin genes: Sequence homology and α-globin gene deletions
    1980 470 citations Che‐Kun James Shen, Tom Maniatis et al. Cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Che‐Kun James Shen Taiwan 11 829 380 264 160 152 16 1.5k
Anthony A. High United States 23 1.2k 1.5× 205 0.5× 328 1.2× 35 0.2× 106 0.7× 44 1.8k
Hong‐Yu Hu China 26 1.3k 1.6× 105 0.3× 470 1.8× 62 0.4× 73 0.5× 83 1.9k
Youhna M. Ayala United States 17 1.7k 2.0× 1.1k 3.0× 1.7k 6.3× 514 3.2× 209 1.4× 22 3.0k
Jamie Longgood United States 10 2.0k 2.5× 140 0.4× 239 0.9× 15 0.1× 107 0.7× 10 2.5k
Lucy Ghoda United States 19 967 1.2× 81 0.2× 42 0.2× 75 0.5× 80 0.5× 43 1.4k
Aldo Pagano Italy 28 1.8k 2.2× 81 0.2× 172 0.7× 15 0.1× 146 1.0× 61 2.4k
Lea Guo United States 16 1.1k 1.3× 74 0.2× 44 0.2× 36 0.2× 41 0.3× 21 1.4k
Don Benjamin Switzerland 12 1.2k 1.5× 76 0.2× 33 0.1× 36 0.2× 90 0.6× 14 1.7k
Débora Bonenfant Switzerland 15 2.1k 2.5× 99 0.3× 28 0.1× 36 0.2× 151 1.0× 19 2.6k
Wilfried Kugler Germany 24 842 1.0× 172 0.5× 30 0.1× 76 0.5× 114 0.8× 40 1.5k

Countries citing papers authored by Che‐Kun James Shen

Since Specialization
Citations

This map shows the geographic impact of Che‐Kun James Shen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Che‐Kun James Shen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Che‐Kun James Shen more than expected).

Fields of papers citing papers by Che‐Kun James Shen

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Che‐Kun James Shen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Che‐Kun James Shen. The network helps show where Che‐Kun James Shen may publish in the future.

Co-authorship network of co-authors of Che‐Kun James Shen

This figure shows the co-authorship network connecting the top 25 collaborators of Che‐Kun James Shen. A scholar is included among the top collaborators of Che‐Kun James Shen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Che‐Kun James Shen. Che‐Kun James Shen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

16 of 16 papers shown
1.
Majumder, Pritha, Sean Chun-Chang Chen, Po‐Hsuan Su, et al.. (2025). Hypoxia-induced genome-wide DNA demethylation by DNMT3A and EMT of cancer cells. Cellular & Molecular Biology Letters. 30(1). 95–95. 1 indexed citations
2.
Rodríguez‐Cueto, Carmen, Fabiana Piscitelli, Anna Lauritano, et al.. (2023). Preclinical investigation in FAAH inhibition as a neuroprotective therapy for frontotemporal dementia using TDP-43 transgenic male mice. Journal of Neuroinflammation. 20(1). 108–108. 7 indexed citations
3.
Wang, I‐Fang, Yihan Wang, Yihua Yang, et al.. (2021). Activation of a hippocampal CREB-pCREB-miRNA-MEF2 axis modulates individual variation of spatial learning and memory capability. Cell Reports. 36(5). 109477–109477. 14 indexed citations
4.
Lee, Tung‐Liang, Kang‐Chung Yang, Yu‐Chiau Shyu, et al.. (2021). A Positive Regulatory Feedback Loop between EKLF/KLF1 and TAL1/SCL Sustaining the Erythropoiesis. International Journal of Molecular Sciences. 22(15). 8024–8024. 4 indexed citations
5.
Shen, Che‐Kun James, et al.. (2021). RNA Modifications and RNA Metabolism in Neurological Disease Pathogenesis. International Journal of Molecular Sciences. 22(21). 11870–11870. 43 indexed citations
6.
Yeh, Teng‐Kuang, Yu‐Chi Chou, Tsu Hsu, et al.. (2020). Potent and orally active purine-based fetal hemoglobin inducers for treating β-thalassemia and sickle cell disease. European Journal of Medicinal Chemistry. 209. 112938–112938. 5 indexed citations
7.
Wu, Cheng‐Chun, et al.. (2016). G-CSF-mobilized Bone Marrow Mesenchymal Stem Cells Replenish Neural Lineages in Alzheimer’s Disease Mice via CXCR4/SDF-1 Chemotaxis. Molecular Neurobiology. 54(8). 6198–6212. 43 indexed citations
8.
Wang, I‐Fang, Kuen‐Jer Tsai, & Che‐Kun James Shen. (2015). Autophagy Activators Rescue and Alleviate the Pathogenesis of a FTLD-TDP model with TDP-43 Proteinopathies (S8.005). Neurology. 84(14_supplement). 1 indexed citations
9.
Wang, I‐Fang, Yu‐Chih Liu, Cheng‐Chun Wu, et al.. (2012). Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43. Proceedings of the National Academy of Sciences. 109(37). 15024–15029. 314 indexed citations
10.
Wang, I‐Fang, Kuen‐Jer Tsai, & Che‐Kun James Shen. (2012). Autophagy activation ameliorates neuronal pathogenesis of FTLD-U mice. Autophagy. 9(2). 239–240. 51 indexed citations
11.
Hsu, Shih‐Lan, et al.. (1988). Structure and expression of the human θl globin gene. Nature. 331(6151). 94–96. 47 indexed citations
12.
Perez‐Stable, Carlos & Che‐Kun James Shen. (1986). Competitive and Cooperative Functioning of the Anterior and Posterior Promoter Elements of an Alu Family Repeat. Molecular and Cellular Biology. 6(6). 2041–2052. 18 indexed citations
13.
Shen, Che‐Kun James, et al.. (1980). The chromosomal arrangement of human α-like globin genes: Sequence homology and α-globin gene deletions. Cell. 20(1). 119–130. 470 indexed citations breakdown →
14.
Isaacs, Stephen T., Che‐Kun James Shen, John E. Hearst, & Henry Rapoport. (1977). Synthesis and characterization of new psoralen derivatives with superior photoreactivity with DNA and RNA. Biochemistry. 16(6). 1058–1064. 281 indexed citations
15.
Shen, Che‐Kun James, Tao‐shih Hsieh, James C. Wang, & John E. Hearst. (1977). Photochemical cross-linking of DNA-RNA helices by psoralen derivatives. Journal of Molecular Biology. 116(4). 661–679. 19 indexed citations
16.
Hanson, Carl V., Che‐Kun James Shen, & John E. Hearst. (1976). Cross-Linking of DNA in Situ as a Probe for Chromatin Structure. Science. 193(4247). 62–64. 157 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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