Charles A. Thornton

18.4k citations

157 papers · 13.7k indexed · 3 hit papers · h-index 66

Molecular Biology top 0.2%
Cellular and Molecular Neuroscience top 0.05%
Neurology top 0.5%
Cardiology and Cardiovascular Medicine top 1%
Physiology top 2%

Co-authors: Stephen Welle Richard T. Moxley Maurice S. Swanson Ami Mankodi Thurman M. Wheeler Krzysztof Sobczak Masayuki Nakamori Robert J. Osborne
Topics: Genetic Neurodegenerative Diseases (106 papers)Muscle Physiology and Disorders (55 papers)Mitochondrial Function and Pathology (45 papers)
Cited by: Cellular and Molecular Neuroscience Molecular Biology Neurology
Journals: Nature Science New England Journal of Medicine
Partner nations: United States Canada Poland

In The Last Decade

Charles A. Thornton

154 papers receiving 13.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A Muscleblind Knockout Model for Myotonic Dystrophy

2003 576 citations Rahul Kanadia, Karen A. Johnstone et al. Science profile →
Myotonic Dystrophy in Transgenic Mice Expressing an Expanded CUG Repeat

2000 554 citations Ami Mankodi, Carolyn McClain et al. Science profile →
Expanded CUG Repeats Trigger Aberrant Splicing of ClC-1 Chloride Channel Pre-mRNA and Hyperexcitability of Skeletal Muscle in Myotonic Dystrophy

2002 513 citations Ami Mankodi, Richard T. Moxley et al. profile →

Peers

Countries citing papers authored by Charles A. Thornton

Since Specialization

Citations

This map shows the geographic impact of Charles A. Thornton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Charles A. Thornton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Charles A. Thornton more than expected).

Fields of papers citing papers by Charles A. Thornton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Charles A. Thornton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Charles A. Thornton. The network helps show where Charles A. Thornton may publish in the future.

Co-authorship network of co-authors of Charles A. Thornton

This figure shows the co-authorship network connecting the top 25 collaborators of Charles A. Thornton. A scholar is included among the top collaborators of Charles A. Thornton based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Charles A. Thornton. Charles A. Thornton is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Towards development of a statistical framework to evaluate myotonic dystrophy type 1 mRNA biomarkers in the context of a clinical trial 2020 ·PLoS ONE ·(unknown),Anneli Cooper,(unknown),Sarah A. Cumming,Berit Adam,Ralf Krahe,Jack Puymirat,Benedikt Schoser,Lubov Timchenko,Tetsuo Ashizawa,Charles A. Thornton,Simon Rogers,John McClure,Darren G. Monckton	12
2	Intron retention induced by microsatellite expansions as a disease biomarker 2018 ·Proceedings of the National Academy of Sciences ·Łukasz J. Sznajder,James D. Thomas,Ellie M. Carrell,Tammy Reid,Karen N. McFarland,John D. Cleary,Ruan Oliveira,Curtis A. Nutter,Kirti Bhatt,Krzysztof Sobczak,Tetsuo Ashizawa,Charles A. Thornton,Laura P.W. Ranum,Maurice S. Swanson	83
3	High frequency of gastrointestinal manifestations in myotonic dystrophy type 1 and type 2 2017 ·Neurology ·James E. Hilbert,Richard J. Barohn,Paula R. Clemens,Elizabeth Luebbe,William B. Martens,Michael McDermott,Amy L. Parkhill,Rabi Tawil,Charles A. Thornton,Richard T. Moxley,Tetsuo Ashizawa,P. Michael Conneally,John Day,Denise A. Figlewicz,(unknown),John T. Kissel,(unknown),Katherine D. Mathews,Donald B. Sanders,Stephen J. Tapscott	37
4	Dose-Dependent Regulation of Alternative Splicing by MBNL Proteins Reveals Biomarkers for Myotonic Dystrophy 2016 ·PLoS Genetics ·Stacey D. Wagner,Adam J. Struck,(unknown),Dylan R. Farnsworth,(unknown),Katy Eichinger,Charles A. Thornton,Eric T. Wang,J. Andrew Berglund	73
5	Dmpkgene deletion or antisense knockdown does not compromise cardiac or skeletal muscle function in mice 2016 ·Human Molecular Genetics ·(unknown),Ellie M. Carrell,David S. Auerbach,Sanjay K. Pandey,C. Frank Bennett,Robert T. Dirksen,Charles A. Thornton	41
6	Detection of Slipped-DNAs at the Trinucleotide Repeats of the Myotonic Dystrophy Type I Disease Locus in Patient Tissues 2013 ·PLoS Genetics ·Michelle M. Axford,Yuh‐Hwa Wang,Masayuki Nakamori,Maria Zannis‐Hadjopoulos,Charles A. Thornton,Christopher E. Pearson	48
7	Diagnostic odyssey of patients with myotonic dystrophy 2013 ·Journal of Neurology ·James E. Hilbert,Tetsuo Ashizawa,John Day,Elizabeth Luebbe,William B. Martens,Michael McDermott,Rabi Tawil,Charles A. Thornton,Richard T. Moxley	72
8	Progressive myopathy in an inducible mouse model of oculopharyngeal muscular dystrophy 2011 ·Neurobiology of Disease ·Ami Mankodi,Thurman M. Wheeler,(unknown),(unknown),Mark W. Bêcher,Charles A. Thornton	17
9	Reversal of RNA Dominance by Displacement of Protein Sequestered on Triplet Repeat RNA 2009 ·Science ·Thurman M. Wheeler,Krzysztof Sobczak,John D. Lueck,Robert J. Osborne,Xiaoyan Lin,Robert T. Dirksen,Charles A. Thornton	303
10	Triplet-repeat oligonucleotide-mediated reversal of RNA toxicity in myotonic dystrophy 2009 ·Proceedings of the National Academy of Sciences ·Susan Mulders,Walther J. A. A. van den Broek,Thurman M. Wheeler,Huib J. E. Croes,Petra van Kuik‐Romeijn,Sjef J. de Kimpe,Denis Furling,Gerard Platenburg,Geneviève Gourdon,Charles A. Thornton,Bé Wieringa,Derick G. Wansink	204
11	Ribonuclear foci at the neuromuscular junction in myotonic dystrophy type 1 2007 ·Neuromuscular Disorders ·Thurman M. Wheeler,(unknown),Charles A. Thornton	44
12	Expression profile of FSHD supports a link between retinal vasculopathy and muscular dystrophy 2006 ·Neurology ·Robert J. Osborne,Stephen Welle,Shannon L. Venance,Charles A. Thornton,Rabi Tawil	112
13	Reversal of RNA missplicing and myotonia after muscleblind overexpression in a mouse poly(CUG) model for myotonic dystrophy 2006 ·Proceedings of the National Academy of Sciences ·Rahul Kanadia,Jihae Shin,Yuan Yuan,Stuart G. Beattie,Thurman M. Wheeler,Charles A. Thornton,Maurice S. Swanson	274
14	Muscle growth after postdevelopmental myostatin gene knockout 2006 ·American Journal of Physiology-Endocrinology and Metabolism ·Stephen Welle,Kirti Bhatt,Carl A. Pinkert,Rabi Tawil,Charles A. Thornton	87
15	A Muscleblind Knockout Model for Myotonic Dystrophybreakdown → 2003 ·Science ·Rahul Kanadia,Karen A. Johnstone,Ami Mankodi,Codrin Lungu,Charles A. Thornton,Douglas W Esson,Adrian M. Timmers,William W. Hauswirth,Maurice S. Swanson	576
16	Inventory of High-Abundance mRNAs in Skeletal Muscle of Normal Men 1999 ·Genome Research ·Stephen Welle,Kirti Bhatt,Charles A. Thornton	98
17	Expansion of the myotonic dystrophy CTG repeat reduces expression of the flanking DMAHP gene 1997 ·Nature Genetics ·Charles A. Thornton,James Wymer,Zachary Simmons,Carolyn McClain,Richard T. Moxley	174
18	Effect of age on muscle hypertrophy induced by resistance training 1996 ·The Journals of Gerontology Series A ·Stephen Welle,Saara Tötterman,Charles A. Thornton	147
19	Myotonic dystrophy with no trinucleotide repeat expansion 1994 ·Annals of Neurology ·Charles A. Thornton,Robert C. Griggs,Richard T. Moxley	138
20	Myotonic dystrophy patients have larger CTG expansions in skeletal muscle than in leukocytes 1994 ·Annals of Neurology ·Charles A. Thornton,Keith Johnson,Richard T. Moxley	219

About Charles A. Thornton

Charles A. Thornton is a scholar working on Cellular and Molecular Neuroscience, Neurology and Molecular Biology, having authored 157 papers that have together received 13.7k indexed citations. Recurring topics across this work include Genetic Neurodegenerative Diseases (106 papers), Muscle Physiology and Disorders (55 papers) and Mitochondrial Function and Pathology (45 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (7.6k citations), Molecular Biology (11.1k citations) and Neurology (2.2k citations). Charles A. Thornton has collaborated with scholars based in United States, Canada and Poland. Frequent co-authors include Stephen Welle, Richard T. Moxley, Maurice S. Swanson, Ami Mankodi, Thurman M. Wheeler, Krzysztof Sobczak, Masayuki Nakamori, Robert J. Osborne, Kirti Bhatt and Rahul Kanadia. Their work appears in journals such as Nature, Science and New England Journal of Medicine.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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