Helmut Grubmüller

34.2k total citations · 9 hit papers
259 papers, 22.9k citations indexed

About

Helmut Grubmüller is a scholar working on Molecular Biology, Atomic and Molecular Physics, and Optics and Materials Chemistry. According to data from OpenAlex, Helmut Grubmüller has authored 259 papers receiving a total of 22.9k indexed citations (citations by other indexed papers that have themselves been cited), including 184 papers in Molecular Biology, 82 papers in Atomic and Molecular Physics, and Optics and 44 papers in Materials Chemistry. Recurrent topics in Helmut Grubmüller's work include Protein Structure and Dynamics (85 papers), Spectroscopy and Quantum Chemical Studies (47 papers) and RNA and protein synthesis mechanisms (38 papers). Helmut Grubmüller is often cited by papers focused on Protein Structure and Dynamics (85 papers), Spectroscopy and Quantum Chemical Studies (47 papers) and RNA and protein synthesis mechanisms (38 papers). Helmut Grubmüller collaborates with scholars based in Germany, United States and United Kingdom. Helmut Grubmüller's co-authors include Bert L. de Groot, Sarah Rauscher, Ting Ran, Michael Feig, Jing Huang, Grzegorz Nawrocki, Oliver F. Lange, Berthold Heymann, Gerrit Groenhof and Martin C. Stumpe and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Helmut Grubmüller

252 papers receiving 22.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

CHARMM36m: an improved force field for folded and intrinsically disordered proteins

2016 4.5k citations Jing Huang, Sarah Rauscher et al. Nature Methods profile →
Recognition Dynamics Up to Microseconds Revealed from an RDC-Derived Ubiquitin Ensemble in Solution

2008 839 citations Stefan Becker, Helmut Grubmüller et al. profile →
Ligand Binding: Molecular Mechanics Calculation of the Streptavidin-Biotin Rupture Force

1996 738 citations Helmut Grubmüller et al. profile →
Water Permeation Across Biological Membranes: Mechanism and Dynamics of Aquaporin-1 and GlpF

2001 709 citations Bert L. de Groot, Helmut Grubmüller profile →
Predicting slow structural transitions in macromolecular systems: Conformational flooding

1995 502 citations Helmut Grubmüller profile →
Membrane protein sequestering by ionic protein–lipid interactions

2011 477 citations Helmut Grubmüller et al. profile →
Anatomy and Dynamics of a Supramolecular Membrane Protein Cluster

2007 345 citations Carsten Kutzner, Helmut Grubmüller et al. profile →
More bang for your buck: Improved use of GPU nodes for GROMACS 2018

2019 297 citations Carsten Kutzner, Bert L. de Groot et al. Journal of Computational Chemistry profile →
Phosphatidylinositol 4,5-bisphosphate clusters act as molecular beacons for vesicle recruitment

2013 216 citations Helmut Grubmüller et al. Nature Structural & Molecular Biology profile →

Peers

Countries citing papers authored by Helmut Grubmüller

Since Specialization

Citations

This map shows the geographic impact of Helmut Grubmüller's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Helmut Grubmüller with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Helmut Grubmüller more than expected).

Fields of papers citing papers by Helmut Grubmüller

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Helmut Grubmüller. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Helmut Grubmüller. The network helps show where Helmut Grubmüller may publish in the future.

Co-authorship network of co-authors of Helmut Grubmüller

This figure shows the co-authorship network connecting the top 25 collaborators of Helmut Grubmüller. A scholar is included among the top collaborators of Helmut Grubmüller based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Helmut Grubmüller. Helmut Grubmüller is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Scaling of the GROMACS Molecular Dynamics Code to 65k CPU Cores on an HPC Cluster 2025 ·Journal of Computational Chemistry ·Carsten Kutzner, (unknown), (unknown), Markus Rampp, Gerhard Hummer, Bert L. de Groot, Helmut Grubmüller	3
2	Structure and function of otoferlin, a synaptic protein of sensory hair cells essential for hearing 2025 ·Science Advances ·Han Chen, Constantin Cretu, (unknown), (unknown), Norbert Babai, Lisa Feldmann, Florian Leidner, Fritz Benseler, (unknown), (unknown), (unknown), Vladimir Peña, Constantin Pape, Helmut Grubmüller, Nicola Strenzke, Nils Brose, Carolin Wichmann, Julia Preobraschenski, Tobias Moser	1
3	Interfacial water confers transcription factors with dinucleotide specificity 2025 ·Nature Structural & Molecular Biology ·Ekaterina Morgunova, Gábor Nagy, Yimeng Yin, Fangjie Zhu, Sonali Nayak, (unknown), (unknown), А. Н. Попов, Charles A. Laughton, Helmut Grubmüller, Jussi Taipale	6
4	Is a Malleable Active Site Loop the Key to High Substrate Promiscuity? Hybrid, Biocatalytic Route to Structurally Diverse Taxoid Side Chains with Remarkable Dual Stereocontrol 2025 ·Angewandte Chemie International Edition ·(unknown), Florian Leidner, N. N. Bhuvan Kumar, (unknown), Peter Madzelan, Douglas R. Powell, Victor W. Day, Pierre Le Maguerès, Joseph D. Ferrara, (unknown), Akihito Yamano, Shô Itô, Wei Niu, Helmut Grubmüller, Mark A. Wilson, David B. Berkowitz	0
5	BPS2025 - A minimal chemo-mechanical Markov model for rotary catalysis of F1-ATPase 2025 ·Biophysical Journal ·Yixin Chen, Helmut Grubmüller	0
6	Constant pH Simulation with FMM Electrostatics in GROMACS. (A) Design and Applications 2025 ·Journal of Chemical Theory and Computation ·(unknown), (unknown), Carsten Kutzner, Helmut Grubmüller	3
7	Reference Data Set for Circular Dichroism Spectroscopy Comprised of Validated Intrinsically Disordered Protein Models 2024 ·Applied Spectroscopy ·Gábor Nagy, Søren Vrønning Hoffmann, Nykola C. Jones, Helmut Grubmüller	5
8	Infrared spectroscopy reveals metal-independent carbonic anhydrase activity in crotonyl-CoA carboxylase/reductase 2024 ·Chemical Science ·(unknown), Matthias Tinzl, (unknown), (unknown), Helmut Grubmüller, Tobias J. Erb, Esteban Vöhringer‐Martinez, Sven T. Stripp	3
9	Determinants of chemoselectivity in ubiquitination by the J2 family of ubiquitin-conjugating enzymes 2024 ·The EMBO Journal ·(unknown), Florian Leidner, Ashok K. Rout, (unknown), Claudia Schmidt, Stefan Becker, Henning Urlaub, Christian Griesinger, Helmut Grubmüller, Alexander Stein	3
10	Conformational Dynamics of the Most Efficient Carboxylase Contributes to Efficient CO ₂ Fixation 2023 ·Journal of Chemical Information and Modeling ·(unknown), Tobias J. Erb, Helmut Grubmüller, Esteban Vöhringer‐Martinez	1
11	Discrimination between cyclic nucleotides in a cyclic nucleotide-gated ion channel 2023 ·Nature Structural & Molecular Biology ·Yangang Pan, (unknown), Philipp A. M. Schmidpeter, Andrea C. Vaiana, Crina M. Nimigean, Helmut Grubmüller, Simon Scheuring	6
12	Molecular mechanism and energetics of coupling between substrate binding and product release in the F ₁ -ATPase catalytic cycle 2023 ·Proceedings of the National Academy of Sciences ·(unknown), Miłosz Wieczór, (unknown), (unknown), Helmut Grubmüller, Jacek Czub	3
13	Folding of VemP into translation-arresting secondary structure is driven by the ribosome exit tunnel 2022 ·Nucleic Acids Research ·Michal H. Kolář, Gábor Nagy, (unknown), Sara M. Vaiana, Lars V. Bock, Helmut Grubmüller	8
14	Choice of fluorophore affects dynamic DNA nanostructures 2021 ·Nucleic Acids Research ·Kevin Jahnke, Helmut Grubmüller, Maxim Igaev, Kerstin Göpfrich	26
15	Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics 2021 ·Nature Communications ·Bertrand Beckert, (unknown), Shanmugapriya Sothiselvam, Lars V. Bock, Maxim S. Svetlov, Michael Graf, Stefan Arenz, (unknown), (unknown), Helmut Grubmüller, Alexander S. Mankin, C.A. Innis, Nora Vázquez‐Laslop, Daniel N. Wilson	58
16	Heterogeneous and rate-dependent streptavidin–biotin unbinding revealed by high-speed force spectroscopy and atomistic simulations 2019 ·Proceedings of the National Academy of Sciences ·Félix Rico, (unknown), Laura López González, Helmut Grubmüller, Simon Scheuring	94
17	Heterogeneous and rate-dependent streptavidin-biotin unbinding revealed by high-speed force spectroscopy and molecular dynamics simulations 2018 ·MPG.PuRe (Max Planck Society) ·Félix Rico, (unknown), Laura López González, Helmut Grubmüller, Simon Scheuring	1
18	CHARMM36m: an improved force field for folded and intrinsically disordered proteins breakdown → 2016 ·Nature Methods ·Jing Huang, Sarah Rauscher, Grzegorz Nawrocki, Ting Ran, Michael Feig, Bert L. de Groot, Helmut Grubmüller, (unknown)	4491
19	Structural Determinants and Mechanism of Mammalian CRM1 Allostery 2013 ·Structure ·Nicole Dölker, Clément Blanchet, (unknown), David Haselbach, Christian Kappel, Thomas Monecke, Dmitri I. Svergun, Holger Stark, Ralf Ficner, Ulrich Zachariae, Helmut Grubmüller, Achim Dickmanns	17
20	Computational Electrophysiology: The Molecular Dynamics of Ion Channel Permeation and Selectivity in Atomistic Detail 2011 ·Biophysical Journal ·Carsten Kutzner, Helmut Grubmüller, Bert L. de Groot, Ulrich Zachariae	173

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact