Catherine L. Tooke

1.9k total citations · 1 hit paper
19 papers, 1.2k citations indexed

About

Catherine L. Tooke is a scholar working on Molecular Medicine, Pharmacology and Epidemiology. According to data from OpenAlex, Catherine L. Tooke has authored 19 papers receiving a total of 1.2k indexed citations (citations by other indexed papers that have themselves been cited), including 17 papers in Molecular Medicine, 10 papers in Pharmacology and 7 papers in Epidemiology. Recurrent topics in Catherine L. Tooke's work include Antibiotic Resistance in Bacteria (17 papers), Antibiotics Pharmacokinetics and Efficacy (9 papers) and Pneumocystis jirovecii pneumonia detection and treatment (6 papers). Catherine L. Tooke is often cited by papers focused on Antibiotic Resistance in Bacteria (17 papers), Antibiotics Pharmacokinetics and Efficacy (9 papers) and Pneumocystis jirovecii pneumonia detection and treatment (6 papers). Catherine L. Tooke collaborates with scholars based in United Kingdom, United States and Canada. Catherine L. Tooke's co-authors include James Spencer, Philip Hinchliffe, Charlotte K. Colenso, Éilís C. Bragginton, Viivi H. A. Hirvonen, Yuiko Takebayashi, Christopher J. Schofield, Jürgen Brem, Adrian J. Mulholland and Robert A. Bonomo and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Journal of Biological Chemistry.

In The Last Decade

Catherine L. Tooke

19 papers receiving 1.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

β-Lactamases and β-Lactamase Inhibitors in the 21st Century

2019 648 citations Catherine L. Tooke, Philip Hinchliffe et al. Journal of Molecular Biology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Catherine L. Tooke United Kingdom	13	822	371	371	246	168	19	1.2k
R.A. Powers United States	19	854 1.0×	395 1.1×	461 1.2×	229 0.9×	119 0.7×	33	1.1k
Thomas F. Durand-Réville United States	16	795 1.0×	252 0.7×	445 1.2×	236 1.0×	120 0.7×	20	1.1k
Kirk Nelson United States	16	905 1.1×	320 0.9×	555 1.5×	266 1.1×	141 0.8×	23	1.2k
Paola Sandra Mercuri Belgium	15	879 1.1×	386 1.0×	274 0.7×	212 0.9×	183 1.1×	42	1.2k
Ronald Domalaon Canada	18	706 0.9×	489 1.3×	329 0.9×	157 0.6×	116 0.7×	23	1.1k
Corey Fyfe United States	12	510 0.6×	235 0.6×	304 0.8×	162 0.7×	142 0.8×	16	840
Ronald E. Painter United States	14	566 0.7×	275 0.7×	347 0.9×	101 0.4×	96 0.6×	14	970
Yuiko Takebayashi United Kingdom	8	539 0.7×	235 0.6×	202 0.5×	110 0.4×	130 0.8×	14	761
Éilís C. Bragginton United Kingdom	4	475 0.6×	293 0.8×	179 0.5×	100 0.4×	119 0.7×	6	781
Nichole K. Stewart United States	14	584 0.7×	326 0.9×	259 0.7×	94 0.4×	95 0.6×	29	822

Countries citing papers authored by Catherine L. Tooke

Since Specialization

Citations

This map shows the geographic impact of Catherine L. Tooke's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Catherine L. Tooke with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Catherine L. Tooke more than expected).

Fields of papers citing papers by Catherine L. Tooke

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Catherine L. Tooke. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Catherine L. Tooke. The network helps show where Catherine L. Tooke may publish in the future.

Co-authorship network of co-authors of Catherine L. Tooke

This figure shows the co-authorship network connecting the top 25 collaborators of Catherine L. Tooke. A scholar is included among the top collaborators of Catherine L. Tooke based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Catherine L. Tooke. Catherine L. Tooke is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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19 of 19 papers shown

1.

Calvopiña, Karina, Philip Hinchliffe, Catherine L. Tooke, et al.. (2025). Electrostatic interactions influence diazabicyclooctane inhibitor potency against OXA-48-like β-lactamases. RSC Medicinal Chemistry. 16(11). 5441–5455. 1 indexed citations

2.

Oliveira, A. Sofia F., et al.. (2024). Dynamical responses predict a distal site that modulates activity in an antibiotic resistance enzyme. Chemical Science. 15(41). 17232–17244. 5 indexed citations

3.

Edwards, Frances L., Fergus Hamilton, Ian M. Head, et al.. (2024). Harvesting and amplifying gene cassettes confers cross-resistance to critically important antibiotics. PLoS Pathogens. 20(6). e1012235–e1012235. 1 indexed citations

4.

Tooke, Catherine L., Philip Hinchliffe, Kirill Zinovjev, et al.. (2023). Tautomer-Specific Deacylation and Ω-Loop Flexibility Explain the Carbapenem-Hydrolyzing Broad-Spectrum Activity of the KPC-2 β-Lactamase. Journal of the American Chemical Society. 145(13). 7166–7180. 16 indexed citations

5.

Hinchliffe, Philip, Catherine L. Tooke, Christopher R. Bethel, et al.. (2022). Penicillanic Acid Sulfones Inactivate the Extended-Spectrum β-Lactamase CTX-M-15 through Formation of a Serine-Lysine Cross-Link: an Alternative Mechanism of β-Lactamase Inhibition. mBio. 13(3). e0179321–e0179321. 9 indexed citations

6.

Malla, Tika R., Karina Calvopiña, Catherine L. Tooke, et al.. (2022). Studies on the Reactions of Biapenem with VIM Metallo β-Lactamases and the Serine β-Lactamase KPC-2. Antibiotics. 11(3). 396–396. 7 indexed citations

7.

Hinchliffe, Philip, Tika R. Malla, Catherine L. Tooke, et al.. (2021). Faropenem reacts with serine and metallo-β-lactamases to give multiple products. European Journal of Medicinal Chemistry. 215. 113257–113257. 15 indexed citations

8.

Galdadas, Ioannis, Shen Qu, A. Sofia F. Oliveira, et al.. (2021). Allosteric communication in class A β-lactamases occurs via cooperative coupling of loop dynamics. eLife. 10. 52 indexed citations

9.

Tooke, Catherine L., Philip Hinchliffe, Robert A. Bonomo, et al.. (2020). Natural variants modify Klebsiella pneumoniae carbapenemase (KPC) acyl–enzyme conformational dynamics to extend antibiotic resistance. Journal of Biological Chemistry. 296. 100126–100126. 33 indexed citations

10.

Tooke, Catherine L., Philip Hinchliffe, Alen Krajnc, et al.. (2020). Cyclic boronates as versatile scaffolds for KPC-2 β-lactamase inhibition. RSC Medicinal Chemistry. 11(4). 491–496. 29 indexed citations

11.

Lohans, Christopher T., Catherine L. Tooke, Philip Hinchliffe, et al.. (2019). Mechanistic Insights into β-Lactamase-Catalysed Carbapenem Degradation Through Product Characterisation. Scientific Reports. 9(1). 13608–13608. 30 indexed citations

12.

Tooke, Catherine L., Philip Hinchliffe, Éilís C. Bragginton, et al.. (2019). β-Lactamases and β-Lactamase Inhibitors in the 21st Century. Journal of Molecular Biology. 431(18). 3472–3500. 648 indexed citations breakdown →

13.

Cain, Ricky, Jonathan M. Tyrrell, Philip Hinchliffe, et al.. (2019). Profiling interactions of vaborbactam with metallo-β-lactamases. Bioorganic & Medicinal Chemistry Letters. 29(15). 1981–1984. 31 indexed citations

14.

Evans, Lindsay E., Thomas E. Webb, Dominic C. Marshall, et al.. (2019). Exploitation of Antibiotic Resistance as a Novel Drug Target: Development of a β-Lactamase-Activated Antibacterial Prodrug. Journal of Medicinal Chemistry. 62(9). 4411–4425. 53 indexed citations

15.

Tooke, Catherine L., Philip Hinchliffe, Pauline A. Lang, et al.. (2019). Molecular Basis of Class A β-Lactamase Inhibition by Relebactam. Antimicrobial Agents and Chemotherapy. 63(10). 60 indexed citations

16.

Lohans, Christopher T., Tika R. Malla, Kiran Kumar, et al.. (2018). Non‐Hydrolytic β‐Lactam Antibiotic Fragmentation by l,d‐Transpeptidases and Serine β‐Lactamase Cysteine Variants. Angewandte Chemie International Edition. 58(7). 1990–1994. 24 indexed citations

17.

Lohans, Christopher T., Tika R. Malla, Kiran Kumar, et al.. (2018). Non‐Hydrolytic β‐Lactam Antibiotic Fragmentation by l,d‐Transpeptidases and Serine β‐Lactamase Cysteine Variants. Angewandte Chemie. 131(7). 2012–2016. 4 indexed citations

18.

Lohans, Christopher T., Kiran Kumar, Catherine L. Tooke, et al.. (2017). A New Mechanism for β‐Lactamases: Class D Enzymes Degrade 1β‐Methyl Carbapenems through Lactone Formation. Angewandte Chemie International Edition. 57(5). 1282–1285. 26 indexed citations

19.

Hinchliffe, Philip, Mariano M. González, María F. Mojica, et al.. (2016). Cross-class metallo-β-lactamase inhibition by bisthiazolidines reveals multiple binding modes. Proceedings of the National Academy of Sciences. 113(26). E3745–54. 111 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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