James Spencer

16.8k total citations · 2 hit papers
222 papers, 11.7k citations indexed

About

James Spencer is a scholar working on Molecular Medicine, Dermatology and Epidemiology. According to data from OpenAlex, James Spencer has authored 222 papers receiving a total of 11.7k indexed citations (citations by other indexed papers that have themselves been cited), including 86 papers in Molecular Medicine, 64 papers in Dermatology and 64 papers in Epidemiology. Recurrent topics in James Spencer's work include Antibiotic Resistance in Bacteria (86 papers), Pneumocystis jirovecii pneumonia detection and treatment (32 papers) and Antibiotics Pharmacokinetics and Efficacy (30 papers). James Spencer is often cited by papers focused on Antibiotic Resistance in Bacteria (86 papers), Pneumocystis jirovecii pneumonia detection and treatment (32 papers) and Antibiotics Pharmacokinetics and Efficacy (30 papers). James Spencer collaborates with scholars based in United Kingdom, United States and Thailand. James Spencer's co-authors include Timothy R. Walsh, Danxia Gu, Hongwei Ren, Xi Huang, Lingxian Yi, Yohei Doi, Jianzhong Shen, Luchao Lv, Yang Wang and Xiaojie Chen and has published in prestigious journals such as Proceedings of the National Academy of Sciences, The Lancet and Journal of the American Chemical Society.

In The Last Decade

James Spencer

218 papers receiving 11.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study

2015 3.9k citations James Spencer et al. profile →
β-Lactamases and β-Lactamase Inhibitors in the 21st Century

2019 648 citations Catherine L. Tooke, Philip Hinchliffe et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
James Spencer United Kingdom	50	6.5k	2.9k	2.3k	2.1k	2.1k	222	11.7k
Xi Huang China	44	4.4k 0.7×	2.9k 1.0×	2.2k 0.9×	995 0.5×	1.1k 0.5×	194	10.8k
Moreno Galleni Belgium	46	5.0k 0.8×	2.9k 1.0×	906 0.4×	1.8k 0.8×	1.3k 0.6×	200	7.5k
Hongwei Ren China	32	3.6k 0.5×	1.9k 0.7×	1.8k 0.8×	813 0.4×	1.0k 0.5×	72	7.3k
Ian Chopra United Kingdom	37	2.2k 0.3×	3.2k 1.1×	1.6k 0.7×	960 0.5×	628 0.3×	89	8.2k
Karl Drlica United States	60	5.2k 0.8×	8.2k 2.8×	705 0.3×	3.7k 1.7×	2.2k 1.0×	170	14.6k
Martti Vaara Finland	48	3.2k 0.5×	4.8k 1.6×	539 0.2×	1.3k 0.6×	1.4k 0.7×	168	11.9k
Peter A. Lambert United Kingdom	44	1.1k 0.2×	2.1k 0.7×	280 0.1×	507 0.2×	919 0.4×	199	7.1k
Andreas Peschel Germany	75	1.6k 0.2×	11.4k 3.9×	173 0.1×	983 0.5×	1.5k 0.7×	211	20.2k
Helle Krogh Johansen Denmark	61	3.1k 0.5×	5.8k 2.0×	233 0.1×	554 0.3×	2.4k 1.1×	229	12.8k
Hui Wang China	54	3.5k 0.5×	2.7k 0.9×	823 0.4×	1.0k 0.5×	2.7k 1.3×	334	10.2k

Countries citing papers authored by James Spencer

Since Specialization

Citations

This map shows the geographic impact of James Spencer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James Spencer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James Spencer more than expected).

Fields of papers citing papers by James Spencer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James Spencer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James Spencer. The network helps show where James Spencer may publish in the future.

Co-authorship network of co-authors of James Spencer

This figure shows the co-authorship network connecting the top 25 collaborators of James Spencer. A scholar is included among the top collaborators of James Spencer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James Spencer. James Spencer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Spencer, James, Bogdan I. Iorga, Jean‐Denis Docquier, et al.. (2025). SAND: a comprehensive annotation of class D β-lactamases using structural alignment-based numbering. Antimicrobial Agents and Chemotherapy. 69(7). e0015025–e0015025. 2 indexed citations

Hinchliffe, Philip, John M. Shaw, Antonia S. J. S. Mey, et al.. (2025). All Roads Lead to Carbinolamine: QM/MM Study of Enzymatic C–N Bond Cleavage in Anaerobic Glycyl Radical Enzyme Choline Trimethylamine-Lyase (CutC). The Journal of Physical Chemistry B. 129(37). 9322–9332.

Hinchliffe, Philip, et al.. (2025). Active site loops of membrane-anchored metallo-β-lactamases from environmental bacteria determine cephalosporinase activity. Antimicrobial Agents and Chemotherapy. 69(8). e0191824–e0191824.

Spencer, James, et al.. (2024). Dynamical nonequilibrium molecular dynamics simulations reveal allosteric networks, signal transduction mechanisms, and sites associated with drug resistance in biomolecular systems. Molecular Physics. 123(7-8). 4 indexed citations

Oliveira, A. Sofia F., et al.. (2024). Dynamical responses predict a distal site that modulates activity in an antibiotic resistance enzyme. Chemical Science. 15(41). 17232–17244. 5 indexed citations

Mojica, María F., Philip Hinchliffe, V. Rodríguez Martínez, et al.. (2024). Rational Design of Benzobisheterocycle Metallo-β-Lactamase Inhibitors: A Tricyclic Scaffold Enhances Potency against Target Enzymes. Journal of Medicinal Chemistry. 67(5). 3795–3812. 1 indexed citations

Spencer, James, et al.. (2024). Electric Fields Are a Key Determinant of Carbapenemase Activity in Class A β-Lactamases. ACS Catalysis. 14(9). 7166–7172. 15 indexed citations

Ounjai, Puey, Sirilata Yotphan, Adrian J. Mulholland, et al.. (2023). Enhancement by pyrazolones of colistin efficacy against mcr-1-expressing E. coli: an in silico and in vitro investigation. Journal of Computer-Aided Molecular Design. 37(10). 479–489.

Ngamwongsatit, Natharin, Puey Ounjai, Sirilata Yotphan, et al.. (2023). Pyrazolones Potentiate Colistin Activity against MCR-1-Producing Resistant Bacteria: Computational and Microbiological Study. ACS Omega. 8(9). 8366–8376. 9 indexed citations

10.

Hinchliffe, Philip, Catherine L. Tooke, Christopher R. Bethel, et al.. (2022). Penicillanic Acid Sulfones Inactivate the Extended-Spectrum β-Lactamase CTX-M-15 through Formation of a Serine-Lysine Cross-Link: an Alternative Mechanism of β-Lactamase Inhibition. mBio. 13(3). e0179321–e0179321. 9 indexed citations

11.

Suardíaz, Reynier, Philip Hinchliffe, Marc W. van der Kamp, et al.. (2021). Catalytic mechanism of the colistin resistance protein MCR-1. Organic & Biomolecular Chemistry. 19(17). 3813–3819. 17 indexed citations

12.

Gervasoni, Silvia, Reynier Suardíaz, Charlotte K. Colenso, et al.. (2021). Multiscale Workflow for Modeling Ligand Complexes of Zinc Metalloproteins. Journal of Chemical Information and Modeling. 61(11). 5658–5672. 11 indexed citations

13.

Hinchliffe, Philip, Diego M. Moreno, María F. Mojica, et al.. (2021). 2-Mercaptomethyl Thiazolidines (MMTZs) Inhibit All Metallo-β-Lactamase Classes by Maintaining a Conserved Binding Mode. ACS Infectious Diseases. 7(9). 2697–2706. 15 indexed citations

14.

Suardíaz, Reynier, Philip Hinchliffe, Surawit Visitsatthawong, et al.. (2020). Resistance to the “last resort” antibiotic colistin: a single-zinc mechanism for phosphointermediate formation in MCR enzymes. Chemical Communications. 56(50). 6874–6877. 12 indexed citations

15.

Tooke, Catherine L., Philip Hinchliffe, Robert A. Bonomo, et al.. (2020). Natural variants modify Klebsiella pneumoniae carbapenemase (KPC) acyl–enzyme conformational dynamics to extend antibiotic resistance. Journal of Biological Chemistry. 296. 100126–100126. 33 indexed citations

16.

Williams, Sam E., Catherine R. Back, Kavita Tiwari, et al.. (2020). The Bristol Sponge Microbiome Collection: A Unique Repository of Deep-Sea Microorganisms and Associated Natural Products. Antibiotics. 9(8). 509–509. 7 indexed citations

17.

Tompa, Emile, James Spencer, Cheryl Peters, et al.. (2018). The economic burden of occupational non-melanoma skin cancer due to solar radiation. Journal of Occupational and Environmental Hygiene. 15(6). 481–491. 43 indexed citations

18.

Hadi, Suhail, et al.. (2006). Treatment of Vitiligo Using the 308-nm Excimer Laser. Photomedicine and Laser Surgery. 24(3). 354–357. 29 indexed citations

19.

Spencer, James. (2002). Immune response modifiers and cutaneous neoplasia.. PubMed. 112(6 Suppl Using). 17–21. 1 indexed citations

20.

Nouri, Keyvan, et al.. (1999). Does Wound Healing Contribute to the Eradication of Basal Cell Carcinoma Following Curettage and Electrodessication?. Dermatologic Surgery. 25(3). 183–188. 23 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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