Philip Hinchliffe

4.0k total citations · 2 hit papers
43 papers, 2.6k citations indexed

About

Philip Hinchliffe is a scholar working on Molecular Medicine, Epidemiology and Molecular Biology. According to data from OpenAlex, Philip Hinchliffe has authored 43 papers receiving a total of 2.6k indexed citations (citations by other indexed papers that have themselves been cited), including 33 papers in Molecular Medicine, 17 papers in Epidemiology and 16 papers in Molecular Biology. Recurrent topics in Philip Hinchliffe's work include Antibiotic Resistance in Bacteria (33 papers), Pneumocystis jirovecii pneumonia detection and treatment (13 papers) and Antibiotics Pharmacokinetics and Efficacy (13 papers). Philip Hinchliffe is often cited by papers focused on Antibiotic Resistance in Bacteria (33 papers), Pneumocystis jirovecii pneumonia detection and treatment (13 papers) and Antibiotics Pharmacokinetics and Efficacy (13 papers). Philip Hinchliffe collaborates with scholars based in United Kingdom, United States and Argentina. Philip Hinchliffe's co-authors include Leonid A. Sazanov, James Spencer, Catherine L. Tooke, Charlotte K. Colenso, Éilís C. Bragginton, Yuiko Takebayashi, Viivi H. A. Hirvonen, Christopher J. Schofield, Jürgen Brem and Colin Hughes and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Philip Hinchliffe

41 papers receiving 2.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

β-Lactamases and β-Lactamase Inhibitors in the 21st Century

2019 648 citations Catherine L. Tooke, Philip Hinchliffe et al. Journal of Molecular Biology profile →
Structure of the Hydrophilic Domain of Respiratory Complex I from Thermus thermophilus

2006 643 citations Leonid A. Sazanov, Philip Hinchliffe Science profile →

Peers

Countries citing papers authored by Philip Hinchliffe

Since Specialization

Citations

This map shows the geographic impact of Philip Hinchliffe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Philip Hinchliffe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Philip Hinchliffe more than expected).

Fields of papers citing papers by Philip Hinchliffe

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Philip Hinchliffe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Philip Hinchliffe. The network helps show where Philip Hinchliffe may publish in the future.

Co-authorship network of co-authors of Philip Hinchliffe

This figure shows the co-authorship network connecting the top 25 collaborators of Philip Hinchliffe. A scholar is included among the top collaborators of Philip Hinchliffe based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Philip Hinchliffe. Philip Hinchliffe is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Electrostatic interactions influence diazabicyclooctane inhibitor potency against OXA-48-like β-lactamases 2025 ·RSC Medicinal Chemistry ·(unknown), (unknown), Karina Calvopiña, (unknown), Philip Hinchliffe, (unknown), Catherine L. Tooke, Yuiko Takebayashi, (unknown), Nicholas J. Harmer, Adrian J. Mulholland, Christopher J. Schofield, (unknown)	1
2	A global survey of intramolecular isopeptide bonds 2025 ·Protein Science ·(unknown), (unknown), Antonina Andreeva, (unknown), (unknown), Philip Hinchliffe, Fabio Parmeggiani, Paul R. Race, Steven G. Burston, (unknown), (unknown)	1
3	Active site loops of membrane-anchored metallo-β-lactamases from environmental bacteria determine cephalosporinase activity 2025 ·Antimicrobial Agents and Chemotherapy ·(unknown), (unknown), Philip Hinchliffe, (unknown), (unknown), Diego M. Moreno, Robert A. Bonomo, James Spencer, Alejandro J. Vila	0
4	All Roads Lead to Carbinolamine: QM/MM Study of Enzymatic C–N Bond Cleavage in Anaerobic Glycyl Radical Enzyme Choline Trimethylamine-Lyase (CutC) 2025 ·The Journal of Physical Chemistry B ·(unknown), (unknown), Philip Hinchliffe, John M. Shaw, Antonia S. J. S. Mey, Natalie Fey, James Spencer, Adrian J. Mulholland	0
5	Rational Design of Benzobisheterocycle Metallo-β-Lactamase Inhibitors: A Tricyclic Scaffold Enhances Potency against Target Enzymes 2024 ·Journal of Medicinal Chemistry ·(unknown), (unknown), María F. Mojica, Philip Hinchliffe, V. Rodríguez Martínez, (unknown), Cecilia Saiz, Claudia Banchio, Mario A. Macías, James Spencer, Robert A. Bonomo, Alejandro J. Vila, Diego M. Moreno, Graciela Mahler	1
6	Dynamical responses predict a distal site that modulates activity in an antibiotic resistance enzyme 2024 ·Chemical Science ·(unknown), A. Sofia F. Oliveira, Catherine L. Tooke, Philip Hinchliffe, (unknown), (unknown), James Spencer, Adrian J. Mulholland	5
7	Penicillanic Acid Sulfones Inactivate the Extended-Spectrum β-Lactamase CTX-M-15 through Formation of a Serine-Lysine Cross-Link: an Alternative Mechanism of β-Lactamase Inhibition 2022 ·mBio ·Philip Hinchliffe, Catherine L. Tooke, Christopher R. Bethel, Benlian Wang, Christopher J. Arthur, Kate J. Heesom, Stuart Shapiro, Daniela Schlatzer, Krisztina M. Papp‐Wallace, Robert A. Bonomo, James Spencer	9
8	2-Mercaptomethyl Thiazolidines (MMTZs) Inhibit All Metallo-β-Lactamase Classes by Maintaining a Conserved Binding Mode 2021 ·ACS Infectious Diseases ·Philip Hinchliffe, Diego M. Moreno, (unknown), María F. Mojica, V. Rodríguez Martínez, (unknown), Brad Spellberg, George L. Drusano, Claudia Banchio, Graciela Mahler, Robert A. Bonomo, Alejandro J. Vila, James Spencer	15
9	Catalytic mechanism of the colistin resistance protein MCR-1 2021 ·Organic & Biomolecular Chemistry ·Reynier Suardíaz, (unknown), Philip Hinchliffe, Marc W. van der Kamp, James Spencer, Natalie Fey, Adrian J. Mulholland	17
10	Faropenem reacts with serine and metallo-β-lactamases to give multiple products 2021 ·European Journal of Medicinal Chemistry ·(unknown), Philip Hinchliffe, Tika R. Malla, Catherine L. Tooke, Jürgen Brem, Karina Calvopiña, Christopher T. Lohans, Patrick Rabe, M.A. McDonough, (unknown), Allen M. Orville, James Spencer, Christopher J. Schofield	15
11	Resistance to the “last resort” antibiotic colistin: a single-zinc mechanism for phosphointermediate formation in MCR enzymes 2020 ·Chemical Communications ·(unknown), Reynier Suardíaz, Philip Hinchliffe, (unknown), Surawit Visitsatthawong, A. Sofia F. Oliveira, Eric J. M. Lang, Panida Surawatanawong, Vannajan Sanghiran Lee, Thanyada Rungrotmongkol, Natalie Fey, James Spencer, Adrian J. Mulholland	12
12	Natural variants modify Klebsiella pneumoniae carbapenemase (KPC) acyl–enzyme conformational dynamics to extend antibiotic resistance 2020 ·Journal of Biological Chemistry ·Catherine L. Tooke, Philip Hinchliffe, Robert A. Bonomo, Christopher J. Schofield, Adrian J. Mulholland, James Spencer	33
13	β-Lactamases and β-Lactamase Inhibitors in the 21st Century breakdown → 2019 ·Journal of Molecular Biology ·Catherine L. Tooke, Philip Hinchliffe, Éilís C. Bragginton, Charlotte K. Colenso, Viivi H. A. Hirvonen, Yuiko Takebayashi, James Spencer	648
14	Crystal structures of VIM‐1 complexes explain active site heterogeneity in VIM‐class metallo‐β‐lactamases 2018 ·FEBS Journal ·(unknown), Philip Hinchliffe, Magda Kosmopoulou, Jonathan M. Tyrrell, Jürgen Brem, Sander S. van Berkel, Anil Kumar Verma, Raymond J. Owens, M.A. McDonough, Timothy R. Walsh, Christopher J. Schofield, James Spencer	32
15	1.12 Å resolution crystal structure of the catalytic domain of the plasmid-mediated colistin resistance determinant MCR-2 2017 ·Acta Crystallographica Section F Structural Biology Communications ·(unknown), Timothy R. Walsh, James Spencer, Philip Hinchliffe	24
16	Sideromimic Modification of Lactivicin Dramatically Increases Potency against Extensively Drug-Resistant Stenotrophomonas maltophilia Clinical Isolates 2016 ·Antimicrobial Agents and Chemotherapy ·Karina Calvopiña, (unknown), Anna M. Rydzik, Philip Hinchliffe, Jürgen Brem, James Spencer, Christopher J. Schofield, Matthew B. Avison	12
17	Structure of the periplasmic adaptor protein from a major facilitator superfamily (MFS) multidrug efflux pump 2014 ·FEBS Letters ·Philip Hinchliffe, Nicholas P. Greene, Neil G. Paterson, Allister Crow, Colin Hughes, Vassilis Koronakis	36
18	Structure of an atypical periplasmic adaptor from a multidrug efflux pump of the spirochete Borrelia burgdorferi 2013 ·FEBS Letters ·Nicholas P. Greene, Philip Hinchliffe, Allister Crow, Abdessamad Ababou, Colin Hughes, Vassilis Koronakis	15
19	Structure of the Hydrophilic Domain of Respiratory Complex I from Thermus thermophilus breakdown → 2006 ·Science ·Leonid A. Sazanov, Philip Hinchliffe	643
20	Organization of Iron-Sulfur Clusters in Respiratory Complex I 2005 ·Science ·Philip Hinchliffe, Leonid A. Sazanov	155

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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