Canio J. Refino

3.5k citations

36 papers · 2.7k indexed · 1 hit paper · h-index 23

Immunology top 2%
Hematology top 2%
- Blood Coagulation and Thrombosis Mechanisms 12
- Iron Metabolism and Disorders 6
- Platelet Disorders and Treatments 4
- Hemophilia Treatment and Research 4
Internal Medicine top 5%
Oncology top 5%
Cancer Research top 5%
- Protease and Inhibitor Mechanisms 8
Pulmonary and Respiratory Medicine
- Blood properties and coagulation 6
Genetics
- Coagulation, Bradykinin, Polyphosphates, and Angioedema 4
Radiology, Nuclear Medicine and Imaging
- Monoclonal and Polyclonal Antibodies Research 4

Co-authors: Jane L. Grogan Sinisa Ivelja Michelle Francesco Eugene Y. Chiang Dan Eaton Irene Tom Hilary Clark Lino C. Gonzalez
Cited by: Immunology Hematology Internal Medicine
Partner nations: United States Switzerland Belgium

In The Last Decade

Canio J. Refino

35 papers receiving 2.5k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2008 The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells

Peers

Countries citing papers authored by Canio J. Refino

Since Specialization

Citations

This map shows the geographic impact of Canio J. Refino's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Canio J. Refino with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Canio J. Refino more than expected).

Fields of papers citing papers by Canio J. Refino

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Canio J. Refino. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Canio J. Refino. The network helps show where Canio J. Refino may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Canio J. Refino, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Canio J. Refino Line = papers co-authored together Canio J. Refino links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	IL-17RC Is Required for IL-17A– and IL-17F–Dependent Signaling and the Pathogenesis of Experimental Autoimmune Encephalomyelitis Yan Hu,Naruhisa Ota,Ivan Peng,Canio J. Refino,Dimitry M. Danilenko,Patrick Caplazi,Wenjun Ouyang	2010	115
2	Targeted depletion of lymphotoxin-α–expressing TH1 and TH17 cells inhibits autoimmune disease Eugene Y. Chiang,Ganesh Kolumam,Xin Yu,Michelle Francesco,Sinisa Ivelja,Ivan Peng,Peter Gribling,Jean Shu,Wyne P. Lee,Canio J. Refino,Mercedesz Balázs,Andrés Paler-Martı́nez,Allen Nguyen,Judy Young,Kai Barck,Richard A.D. Carano,R Ferrando,Lauri Diehl,Devavani Chatterjea,Jane L. Grogan	2009	142
3	The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cellsbreakdown → Xin Yu,Kristin Harden,Lino C. Gonzalez,Michelle Francesco,Eugene Y. Chiang,Bryan Irving,Irene Tom,Sinisa Ivelja,Canio J. Refino,Hilary Clark,Dan Eaton,Jane L. Grogan	2008	1118
4	A Selective, Slow Binding Inhibitor of Factor VIIa Binds to a Nonstandard Active Site Conformation and Attenuates Thrombus Formation in Vivo Alan G. Olivero,Charles Eigenbrot,Richard Goldsmith,Kirk Robarge,Dean R. Artis,John A. Flygare,Thomas E. Rawson,Daniel P. Sutherlin,Saloumeh Kadkhodayan,Maureen H. Beresini,Linda O. Elliott,Geralyn G. DeGuzman,David W. Banner,Mark Ultsch,Ulla M. Marzec,Stephen R. Hanson,Canio J. Refino,Stuart Bunting,Daniel Kirchhofer	2005	36
5	A Human Antibody that Binds to the γ-carboxyglutamic Acid Domain of Factor IX Is a Potent Antithrombotic In Vivo Jacques Himber,Louis Burcklen,Paul Moran,Mark Peek,Shelley Suggett,Brigitte Devaux,Daniel Kirchhofer,Canio J. Refino	1999	20
6	Pharmacokinetics, Pharmacodynamics and Tolerability of a Potent, Non-peptidic, GP IIb/IIIa Receptor Antagonist following Multiple Oral Administrations of a Prodrug Form Nishit B. Modi,Sherron Bullens,Cheryl Pater,Michael T. Lipari,Kirk Robarge,Brent Blackburn,Maureen H. Beresini,Thomas Weller,Beat Steiner,Stuart Bunting,Canio J. Refino	1998	22
7	An Experimental Model of Intracranial Hemorrhage during Thrombolytic Therapy with t-PA Nicholas F. Paoni,Hope Steinmetz,Nancy A. Gillett,Canio J. Refino,Julie M Badillo,Stuart Bunting	1996	5
8	New Variant of Human Tissue Plasminogen Activator (TPA) With Enhanced Efficacy and Lower Incidence of Bleeding Compared With Recombinant Human TPA Claude R. Benedict,Canio J. Refino,Bruce A. Keyt,Rajbabu Pakala,Nicholas F. Paoni,George Thomas,William F. Bennett	1995	131
9	Increasing the fibrin specificity of t-PA enhances its activity towards platelet rich clots Canio J. Refino,Julie M Badillo,Nicholas F. Paoni,Bruce A. Ket,Hung Van Nguyen,William F. Bennett	1994	1
10	Comparative Thrombolytic Properties of Tissue-Type Plasminogen Activator and of a Plasminogen Activator Inhibitor-1 -Resistant Glycosylation Variant, in a Combined Arterial and Venous Thrombosis Model in the Dog Désiré Collen,Jean–Marie Stassen,Tsunehiro Yasuda,Canio J. Refino,Nicholas F. Paoni,Bruce A. Keyt,Tania Roskams,J. Luis Guerrero,Henri R Lijnen,Herman K. Gold,William F. Bennett	1994	63
11	A Variant of t-PA (T103N, KHRR 296-299 AAAA) that, by Bolus, Has Increased Potency and Decreased Systemic Activation of Plasminogen Canio J. Refino,Nicholas F. Paoni,Bruce A. Keyt,Cheryl Pater,Julie M Badillo,Florian Wurm,John R. Ogez,William F. Bennett	1993	46
12	Involvement of residues 296–299 in the enzymatic activity of tissue-type plasminogen activator Nicholas F. Paoni,Canio J. Refino,Kevin Brady,Luis C. Peña,Hung Van Nguyen,Elizabeth M. Kerr,Adriana C. Johnson,Florian Μ. Wurm,Robert van Reis,David Botstein,William F. Bennett	1992	11
13	The Influence of Carbohydrate Structure on the Clearance of Recombinant Tissue-Type Plasminogen Activator Arland T. Hotchkiss,Canio J. Refino,C K Leonard,John O’Connor,Claire Crowley,Jacob W. McCabe,K. Tate,Gerald Nakamura,David B. Powers,Arthur D. Levinson,M Möhler,Michael W. Spellman	1988	88
14	62 Modification of rt-PA oligosaccharide structures to increase or decrease biological clearance Arland T. Hotchkiss,Canio J. Refino,José‐Enrique O’Connor,K. Tate,Jun Nakamura,C K Leonard,David Powers,M Möhler,James McCabe,SHANE ANDERSON,Michael Spellman	1988	2
15	D-Phe-Pro-Arg-Chloromethylketone: Its Potential Use in Inhibiting the Formation of In Vitro Artifacts in Blood Collected During Tissue-Type Plasminogen Activator Thrombolytic Therapy M Möhler,Canio J. Refino,S A Chen,A B Chen,Adair J. Hotchkiss	1986	59
16	Rate of repair of iron deficiency anemia and blood loss anemia in young and mature rats Canio J. Refino,P. R. Dallman	1983	4
17	Sequence of development of iron deficiency in the rat P. R. Dallman,Canio J. Refino,MJ Yland	1982	26
18	Physiological anemia of early development in the rat: characterization of the iron-responsive component Martti A. Siimes,Canio J. Refino,P. R. Dallman	1980	17
19	Manifestation of iron deficiency at various levels of dietary iron intake Martti A. Siimes,Canio J. Refino,P. R. Dallman	1980	90
20	Transfer of Carbon and Hydrogen Across the Mitochondrial Membrane in the Control of Gluconeogenesis Julius H. Anderson,William J. Nicklas,Β. Blank,Canio J. Refino,John Williamson	1971	18

About Canio J. Refino

Canio J. Refino is a scholar working on Hematology, Genetics and Cancer Research, having authored 36 papers that have together received 2.7k indexed citations. Recurring topics across this work include Blood Coagulation and Thrombosis Mechanisms (12 papers), Protease and Inhibitor Mechanisms (8 papers), Blood properties and coagulation (6 papers), Iron Metabolism and Disorders (6 papers), Platelet Disorders and Treatments (4 papers), Coagulation, Bradykinin, Polyphosphates, and Angioedema (4 papers), Hemophilia Treatment and Research (4 papers) and Monoclonal and Polyclonal Antibodies Research (4 papers). The work is most often cited by research in Immunology (1.1k citations), Hematology (584 citations) and Internal Medicine (133 citations). Canio J. Refino has collaborated with scholars based in United States, Switzerland and Belgium. Frequent co-authors include Jane L. Grogan, Sinisa Ivelja, Michelle Francesco, Eugene Y. Chiang, Dan Eaton, Irene Tom, Hilary Clark, Lino C. Gonzalez, Bryan Irving and Xin Yu.

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