Wyne P. Lee

23.9k total citations · 5 hit papers
63 papers, 12.8k citations indexed

About

Wyne P. Lee is a scholar working on Immunology, Molecular Biology and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, Wyne P. Lee has authored 63 papers receiving a total of 12.8k indexed citations (citations by other indexed papers that have themselves been cited), including 37 papers in Immunology, 20 papers in Molecular Biology and 15 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in Wyne P. Lee's work include T-cell and B-cell Immunology (22 papers), Immune Cell Function and Interaction (15 papers) and Monoclonal and Polyclonal Antibodies Research (14 papers). Wyne P. Lee is often cited by papers focused on T-cell and B-cell Immunology (22 papers), Immune Cell Function and Interaction (15 papers) and Monoclonal and Polyclonal Antibodies Research (14 papers). Wyne P. Lee collaborates with scholars based in United States, France and Russia. Wyne P. Lee's co-authors include Vishva M. Dixit, Kim Newton, Meron Roose-Girma, Denise M. Monack, Sanjeev Mariathasan, Jacqueline McBride, Nobuhiko Kayagaki, David S. Weiss, Karen O’Rourke and Yvette Weinrauch and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Wyne P. Lee

63 papers receiving 12.6k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Cryopyrin activates the inflammasome in response to toxins and ATP

2006 2.5k citations Sanjeev Mariathasan, Kim Newton et al. Nature profile →
Non-canonical inflammasome activation targets caspase-11

2011 2.0k citations Nobuhiko Kayagaki, Søren Warming et al. Nature profile →
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

2004 1.5k citations Sanjeev Mariathasan, Kim Newton et al. Nature profile →
Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4

2013 1.2k citations Nobuhiko Kayagaki, Michael T. Wong et al. Science profile →
Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

2009 680 citations Shahram Misaghi, Wyne P. Lee et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Wyne P. Lee United States	43	8.0k	6.2k	1.4k	1.4k	843	63	12.8k
Liliana Schaefer Germany	64	6.5k 0.8×	2.8k 0.5×	1.3k 0.9×	1.2k 0.9×	1.0k 1.2×	193	14.0k
Sanjeev Mariathasan United States	38	6.2k 0.8×	5.9k 1.0×	885 0.6×	1.1k 0.8×	387 0.5×	92	11.0k
Christian Kurts Germany	66	3.4k 0.4×	9.7k 1.6×	1.7k 1.2×	1.0k 0.7×	1.4k 1.7×	196	14.9k
Jörg Köhl Germany	59	2.4k 0.3×	6.4k 1.0×	1.2k 0.9×	652 0.5×	650 0.8×	197	10.8k
Sergei A. Nedospasov Russia	60	4.1k 0.5×	6.4k 1.0×	1.1k 0.8×	1.0k 0.8×	219 0.3×	239	12.2k
Cord Sunderkötter Germany	54	3.7k 0.5×	4.2k 0.7×	1.6k 1.1×	801 0.6×	204 0.2×	239	11.4k
Kelly M. McNagny Canada	50	5.1k 0.6×	4.3k 0.7×	596 0.4×	1.7k 1.3×	498 0.6×	163	11.5k
Marina Botto United Kingdom	67	2.9k 0.4×	10.0k 1.6×	1.8k 1.3×	674 0.5×	1.7k 2.0×	193	14.8k
David J. Rawlings United States	67	5.2k 0.6×	9.5k 1.5×	1.1k 0.8×	824 0.6×	180 0.2×	260	16.3k
Jonathan S. Bromberg United States	65	3.5k 0.4×	8.7k 1.4×	1.5k 1.1×	3.9k 2.9×	810 1.0×	348	17.1k

Countries citing papers authored by Wyne P. Lee

Since Specialization

Citations

This map shows the geographic impact of Wyne P. Lee's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Wyne P. Lee with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Wyne P. Lee more than expected).

Fields of papers citing papers by Wyne P. Lee

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Wyne P. Lee. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Wyne P. Lee. The network helps show where Wyne P. Lee may publish in the future.

Co-authorship network of co-authors of Wyne P. Lee

This figure shows the co-authorship network connecting the top 25 collaborators of Wyne P. Lee. A scholar is included among the top collaborators of Wyne P. Lee based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Wyne P. Lee. Wyne P. Lee is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Bao, Katherine, Juan Zhang, Alexis Scherl, et al.. (2022). Activation-Induced Cytidine Deaminase Impacts the Primary Antibody Repertoire in Naive Mice. The Journal of Immunology. 208(12). 2632–2642. 2 indexed citations

Katewa, Arna, Eric Suto, Jessica Hui, et al.. (2021). The peptide symporter SLC15a4 is essential for the development of systemic lupus erythematosus in murine models. PLoS ONE. 16(1). e0244439–e0244439. 19 indexed citations

Katschke, Kenneth J., Hongkang Xi, Christian L. Cox, et al.. (2018). Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy. Scientific Reports. 8(1). 7348–7348. 52 indexed citations

Chang, Michael, Karpagam Srinivasan, Brad A. Friedman, et al.. (2017). Progranulin deficiency causes impairment of autophagy and TDP-43 accumulation. The Journal of Experimental Medicine. 214(9). 2611–2628. 96 indexed citations

Kolumam, Ganesh, Xiumin Wu, Wyne P. Lee, et al.. (2017). IL-22R Ligands IL-20, IL-22, and IL-24 Promote Wound Healing in Diabetic db/db Mice. PLoS ONE. 12(1). e0170639–e0170639. 68 indexed citations

Xi, Hongkang, Kenneth J. Katschke, Yun Li, et al.. (2016). IL-33 amplifies an innate immune response in the degenerating retina. The Journal of Experimental Medicine. 213(2). 189–207. 75 indexed citations

Holmes, Derek A, Eric Suto, Wyne P. Lee, et al.. (2015). Autoimmunity-associated protein tyrosine phosphatase PEP negatively regulates IFN-α receptor signaling. The Journal of Experimental Medicine. 212(7). 1081–1093. 22 indexed citations

Lin, Zhonghua, Nancy Chiang, Ning Chai, et al.. (2014). In vivo antigen-driven plasmablast enrichment in combination with antigen-specific cell sorting to facilitate the isolation of rare monoclonal antibodies from human B cells. Nature Protocols. 9(7). 1563–1577. 19 indexed citations

Kayagaki, Nobuhiko, Michael T. Wong, Irma B. Stowe, et al.. (2013). Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4. Science. 341(6151). 1246–1249. 1214 indexed citations breakdown →

10.

Nakamura, Gerald, Ning Chai, Summer Park, et al.. (2013). An In Vivo Human-Plasmablast Enrichment Technique Allows Rapid Identification of Therapeutic Influenza A Antibodies. Cell Host & Microbe. 14(1). 93–103. 135 indexed citations

11.

Lugt, Bryan Vander, Aly A. Khan, Jason A. Hackney, et al.. (2013). Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation. Nature Immunology. 15(2). 161–167. 204 indexed citations

12.

Jackman, Janet, Yongmei Chen, Arthur Huang, et al.. (2010). Development of a Two-part Strategy to Identify a Therapeutic Human Bispecific Antibody That Inhibits IgE Receptor Signaling. Journal of Biological Chemistry. 285(27). 20850–20859. 68 indexed citations

13.

Misaghi, Shahram, Christopher Garris, Yonglian Sun, et al.. (2010). Increased Targeting of Donor Switch Region and IgE in Sγ1-Deficient B Cells. The Journal of Immunology. 185(1). 166–173. 14 indexed citations

14.

Campa, Claudio, Ian Kasman, Weilan Ye, et al.. (2008). Effects of an Anti–VEGF-A Monoclonal Antibody on Laser-Induced Choroidal Neovascularization in Mice: Optimizing Methods to Quantify Vascular Changes. Investigative Ophthalmology & Visual Science. 49(3). 1178–1178. 60 indexed citations

15.

McBride, Jacqueline, Henry Chiu, Linda Rangell, et al.. (2008). Genetic deletion of JAM-C reveals a role in myeloid progenitor generation. Blood. 113(9). 1919–1928. 38 indexed citations

16.

Gong, Qian, Qinglin Ou, Shiming Ye, et al.. (2005). Importance of Cellular Microenvironment and Circulatory Dynamics in B Cell Immunotherapy. The Journal of Immunology. 174(2). 817–826. 423 indexed citations

17.

Mariathasan, Sanjeev, Kim Newton, Denise M. Monack, et al.. (2004). Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature. 430(6996). 213–218. 1475 indexed citations breakdown →

18.

Ruefli-Brasse, Astrid, Wyne P. Lee, Stephen Hurst, & Vishva M. Dixit. (2004). Rip2 Participates in Bcl10 Signaling and T-cell Receptor-mediated NF-κB Activation. Journal of Biological Chemistry. 279(2). 1570–1574. 77 indexed citations

19.

Lee, Wyne P., et al.. (1994). Regulation of Experimental Autoimmune Neuritis by Transforming Growth Factor-β1. Cellular Immunology. 156(1). 102–112. 21 indexed citations

20.

Beck, Laurent, Theresa L. Chen, Sue E. Hirabayashi, et al.. (1990). Accelerated Healing of Ulcer Wounds in the Rabbit Ear by Recombinant Human Transforming Growth Factor-β1. Growth Factors. 2(4). 273–282. 44 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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