Wyne P. Lee

23.9k citations

63 papers · 12.8k indexed · 5 hit papers · h-index 43

Molecular Biology top 0.5%
Immunology top 0.2%
Epidemiology top 2%
Surgery top 2%
Nephrology top 0.5%

Co-authors: Vishva M. Dixit Kim Newton Meron Roose-Girma Sanjeev Mariathasan Denise M. Monack Jacqueline McBride Nobuhiko Kayagaki David S. Weiss
Topics: T-cell and B-cell Immunology (22 papers)Immune Cell Function and Interaction (15 papers)Monoclonal and Polyclonal Antibodies Research (14 papers)
Cited by: Immunology Nephrology Molecular Biology
Journals: Nature Science Cell
Partner nations: United States France Russia

In The Last Decade

Wyne P. Lee

63 papers receiving 12.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Cryopyrin activates the inflammasome in response to toxins and ATP

2006 2.5k citations Sanjeev Mariathasan, Kim Newton et al. Nature profile →
Non-canonical inflammasome activation targets caspase-11

2011 2.0k citations Nobuhiko Kayagaki, Søren Warming et al. Nature profile →
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

2004 1.5k citations Sanjeev Mariathasan, Kim Newton et al. Nature profile →
Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4

2013 1.2k citations Nobuhiko Kayagaki, Michael T. Wong et al. Science profile →
Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

2009 680 citations Mohamed Lamkanfi, Wyne P. Lee et al. profile →

Peers

Countries citing papers authored by Wyne P. Lee

Since Specialization

Citations

This map shows the geographic impact of Wyne P. Lee's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Wyne P. Lee with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Wyne P. Lee more than expected).

Fields of papers citing papers by Wyne P. Lee

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Wyne P. Lee. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Wyne P. Lee. The network helps show where Wyne P. Lee may publish in the future.

Co-authorship network of co-authors of Wyne P. Lee

This figure shows the co-authorship network connecting the top 25 collaborators of Wyne P. Lee. A scholar is included among the top collaborators of Wyne P. Lee based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Wyne P. Lee. Wyne P. Lee is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Activation-Induced Cytidine Deaminase Impacts the Primary Antibody Repertoire in Naive Mice 2022 ·The Journal of Immunology ·Katherine Bao,Juan Zhang,Alexis Scherl,James Ziai,(unknown),Daqi Xu,(unknown),(unknown),Yuxin Liang,Lucinda Tam,(unknown),Merone Roose‐Girma,Søren Warming,Zora Modrušan,Wyne P. Lee,Kam Hon Hoi,Ali A. Zarrin	2
2	The peptide symporter SLC15a4 is essential for the development of systemic lupus erythematosus in murine models 2021 ·PLoS ONE ·Arna Katewa,Eric Suto,Jessica Hui,(unknown),Jie Liang,Jason A. Hackney,Keith R. Anderson,(unknown),(unknown),Debra Dunlap,Jeffrey Eastham,Andrés Paler-Martı́nez,(unknown),Zora Modrušan,Wyne P. Lee,Cary D. Austin,Daniel Lafkas,Nico Ghilardi	19
3	Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy 2018 ·Scientific Reports ·Kenneth J. Katschke,Hongkang Xi,Christian L. Cox,Tom Truong,Yann Malato,Wyne P. Lee,Brent S. McKenzie,Rommel Arceo,Jianhua Tao,Linda Rangell,Mike Reichelt,Lauri Diehl,Justin Elstrott,Robby M. Weimer,Menno van Lookeren Campagne	52
4	Progranulin deficiency causes impairment of autophagy and TDP-43 accumulation 2017 ·The Journal of Experimental Medicine ·Michael Chang,Karpagam Srinivasan,Brad A. Friedman,Eric Suto,Zora Modrušan,Wyne P. Lee,Joshua S. Kaminker,Matthew H. Bailey,Morgan Sheng	96
5	IL-22R Ligands IL-20, IL-22, and IL-24 Promote Wound Healing in Diabetic db/db Mice 2017 ·PLoS ONE ·Ganesh Kolumam,Xiumin Wu,Wyne P. Lee,Jason A. Hackney,Jose Zavala‐Solorio,Vineela Gandham,Dimitry M. Danilenko,Puneet Arora,Xiaoting Wang,Wenjun Ouyang	68
6	Potassium channels Kv1.3 and KCa3.1 cooperatively and compensatorily regulate antigen-specific memory T cell functions 2017 ·Nature Communications ·Eugene Y. Chiang,Tianbo Li,Surinder Jeet,Ivan Peng,Juan Zhang,Wyne P. Lee,Jason DeVoss,Patrick Caplazi,Jun Chen,Søren Warming,David H. Hackos,Susmith Mukund,Christopher M. Koth,Jane L. Grogan	83
7	IL-33 amplifies an innate immune response in the degenerating retina 2016 ·The Journal of Experimental Medicine ·Hongkang Xi,Kenneth J. Katschke,Yun Li,Tom Truong,Wyne P. Lee,Lauri Diehl,Linda Rangell,Jianhua Tao,Rommel Arceo,Jeffrey Eastham‐Anderson,Jason A. Hackney,Antonio Iglesias,Javier Cote-Sierra,Justin Elstrott,Robby M. Weimer,Menno van Lookeren Campagne	75
8	Coordinated ubiquitination and phosphorylation of RIP1 regulates necroptotic cell death 2016 ·Cell Death and Differentiation ·M. Cristina de Almagro,Tatiana Goncharov,Anita Izrael-Tomasevic,(unknown),Matthias Kist,Eugene Varfolomeev,Xiumin Wu,Wyne P. Lee,Jeremy Murray,Joshua D. Webster,Kebing Yu,Donald S. Kirkpatrick,Kim Newton,Domagoj Vucic	95
9	Autoimmunity-associated protein tyrosine phosphatase PEP negatively regulates IFN-α receptor signaling 2015 ·The Journal of Experimental Medicine ·Derek A Holmes,Eric Suto,Wyne P. Lee,Qinglin Ou,Qian Gong,Hamish R.C. Smith,Patrick Caplazi,Andrew C. Chan	22
10	In vivo antigen-driven plasmablast enrichment in combination with antigen-specific cell sorting to facilitate the isolation of rare monoclonal antibodies from human B cells 2014 ·Nature Protocols ·Zhonghua Lin,Nancy Chiang,Ning Chai,Dhaya Seshasayee,Wyne P. Lee,Mercedesz Balázs,Gerald Nakamura,Lee R. Swem	19
11	Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4breakdown → 2013 ·Science ·Nobuhiko Kayagaki,Michael T. Wong,Irma B. Stowe,Sree R. Ramani,Lino C. Gonzalez,Sachiko Akashi‐Takamura,Kensuke Miyake,Juan Zhang,Wyne P. Lee,Artur Muszyński,Lennart S. Forsberg,Russell W. Carlson,Vishva M. Dixit	1214
12	Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation 2013 ·Nature Immunology ·Bryan Vander Lugt,Aly A. Khan,Jason A. Hackney,Smita Agrawal,Justin Lesch,Meijuan Zhou,Wyne P. Lee,Summer Park,Min Xu,Jason DeVoss,Chauncey J. Spooner,Cécile Chalouni,Lélia Delamarre,Ira Mellman,Harinder Singh	204
13	Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1 2013 ·Nature Immunology ·Chauncey J. Spooner,Justin Lesch,Donghong Yan,Aly A. Khan,(unknown),Vladimir Ramirez-Carrozzi,Meijuan Zhou,Robert Soriano,Jeffrey Eastham‐Anderson,Lauri Diehl,Wyne P. Lee,Zora Modrušan,Rajita Pappu,Min Xu,Jason DeVoss,Harinder Singh	140
14	Non-canonical inflammasome activation targets caspase-11breakdown → 2011 ·Nature ·Nobuhiko Kayagaki,Søren Warming,Mohamed Lamkanfi,Lieselotte Vande Walle,Salina Louie,Jennifer J. Dong,Kim Newton,Yan Qu,Jinfeng Liu,Sherry Heldens,Juan Zhang,Wyne P. Lee,Merone Roose‐Girma,Vishva M. Dixit	2015
15	Development of a Two-part Strategy to Identify a Therapeutic Human Bispecific Antibody That Inhibits IgE Receptor Signaling 2010 ·Journal of Biological Chemistry ·Janet Jackman,Yongmei Chen,Arthur Huang,Barbara Moffat,Justin M. Scheer,Steven R. Leong,Wyne P. Lee,Juan Zhang,Navneet Sharma,Yanmei Lu,Suhasini Iyer,Robert L. Shields,Nan Chiang,Michele Bauer,(unknown),Merone Roose‐Girma,Richard Vandlen,Daniel G. Yansura,Yan Wu,Lawren C. Wu	68
16	Effects of an Anti–VEGF-A Monoclonal Antibody on Laser-Induced Choroidal Neovascularization in Mice: Optimizing Methods to Quantify Vascular Changes 2008 ·Investigative Ophthalmology & Visual Science ·Claudio Campa,Ian Kasman,Weilan Ye,Wyne P. Lee,Germaine Fuh,Napoleone Ferrara	60
17	Importance of Cellular Microenvironment and Circulatory Dynamics in B Cell Immunotherapy 2005 ·The Journal of Immunology ·Qian Gong,Qinglin Ou,Shiming Ye,Wyne P. Lee,Jennine Cornelius,Lauri Diehl,Wei Lin,Zhilan Hu,Yanmei Lu,Yongmei Chen,Yan Wu,Y. Gloria Meng,Peter Gribling,Zhonghua Lin,Kathy Nguyen,Thanhvien Tran,Yifan Zhang,Hugh Rosen,Flavius Martin,Andrew C. Chan	423
18	Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipafbreakdown → 2004 ·Nature ·Sanjeev Mariathasan,Kim Newton,Denise M. Monack,Domagoj Vucic,Dorothy French,Wyne P. Lee,Meron Roose-Girma,Sharon Erickson,Vishva M. Dixit	1475
19	NTB-A, a New Activating Receptor in T Cells That Regulates Autoimmune Disease 2004 ·Journal of Biological Chemistry ·Patricia Valdez,Hua Wang,Dhaya Seshasayee,Menno van Lookeren Campagne,Austin Gurney,Wyne P. Lee,Iqbal S. Grewal	59
20	A Novel in Vivo Role for Osteoprotegerin Ligand in Activation of Monocyte Effector Function and Inflammatory Response 2004 ·Journal of Biological Chemistry ·Dhaya Seshasayee,Hua Wang,Wyne P. Lee,Peter Gribling,Jed Ross,Nicholas van Bruggen,Richard A.D. Carano,Iqbal S. Grewal	56

About Wyne P. Lee

Wyne P. Lee is a scholar working on Immunology, Rehabilitation and Immunology and Allergy, having authored 63 papers that have together received 12.8k indexed citations. Recurring topics across this work include T-cell and B-cell Immunology (22 papers), Immune Cell Function and Interaction (15 papers) and Monoclonal and Polyclonal Antibodies Research (14 papers). The work is most often cited by research in Immunology (6.2k citations), Nephrology (843 citations) and Molecular Biology (8.0k citations). Wyne P. Lee has collaborated with scholars based in United States, France and Russia. Frequent co-authors include Vishva M. Dixit, Kim Newton, Meron Roose-Girma, Sanjeev Mariathasan, Denise M. Monack, Jacqueline McBride, Nobuhiko Kayagaki, David S. Weiss, Yvette Weinrauch and Karen O’Rourke. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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