Kristian Birchall

1.2k citations

30 papers · 733 indexed · h-index 17

Computational Theory and Mathematics top 2%
- Computational Drug Discovery Methods 14
Organic Chemistry top 10%
Molecular Biology
- Bioinformatics and Genomic Networks 3
- Protein Structure and Dynamics 2
Infectious Diseases
Public Health, Environmental and Occupational Health
- Malaria Research and Control 6
Materials Chemistry
- Machine Learning in Materials Science 4
Pharmacology
- Microbial Natural Products and Biosynthesis 3
- Pharmacogenetics and Drug Metabolism 2
Epidemiology
- Trypanosoma species research and implications 3

Co-authors: Valerie J. Gillet Andy Merritt Gavin Harper Stephen D. Pickett Debra L. Taylor Nathalie Bouloc Timothy M. Chapman Simon A. Osborne
Cited by: Computational Theory and Mathematics Organic Chemistry Molecular Biology
Journals: Journal of Biological Chemistry (1 paper)Bioinformatics (1 paper)Scientific Reports (2 papers)
Partner nations: United Kingdom Tanzania Czechia

In The Last Decade

Kristian Birchall

29 papers receiving 716 citations

Peers

Countries citing papers authored by Kristian Birchall

Since Specialization

Citations

This map shows the geographic impact of Kristian Birchall's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kristian Birchall with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kristian Birchall more than expected).

Fields of papers citing papers by Kristian Birchall

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kristian Birchall. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kristian Birchall. The network helps show where Kristian Birchall may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Kristian Birchall, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Kristian Birchall Line = papers co-authored together Kristian Birchall links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Design and Synthesis of Pyrazoline Inhibitors of SARS-CoV-2 NSP14 ACS Medicinal Chemistry Letters ·Elizabeth Smyth,João Pedro Pisco,Kristian Birchall,Nicole Upfold,Arvind H. Patel,Richard Foster,Jonathan M. Large	2025	0
2	Robustly interrogating machine learning-based scoring functions: what are they learning? Bioinformatics ·G. J. DURANT,Fergus Boyles,Kristian Birchall,Brian D. Marsden,Charlotte M. Deane	2025	8
3	The future of machine learning for small-molecule drug discovery will be driven by data Nature Computational Science ·G. J. DURANT,Fergus Boyles,Kristian Birchall,Charlotte M. Deane	2024	12
4	Targeted protein degradation in CNS disorders: a promising route to novel therapeutics? Frontiers in Molecular Neuroscience ·Sandra Kuemper,Andrew G. Cairns,Kristian Birchall,Zhi Yao,Jonathan M. Large	2024	7
5	Natural mutations of human XDH promote the nitrite (NO2−)-reductase capacity of xanthine oxidoreductase: A novel mechanism to promote redox health? Redox Biology ·Gianmichele Massimo,Rayomand S. Khambata,Tara Chapman,Kristian Birchall,Claudio Raimondi,Aqsa Shabbir,Nicki Dyson,Krishnaraj S. Rathod,Claudio Borghi,Amrita Ahluwalia	2023	3
6	Identification of novel p-cresol inhibitors that reduce Clostridioides difficile’s ability to compete with species of the gut microbiome Scientific Reports ·Mark A. Harrison,Rebecca J. Farthing,Nyasha Allen,Lucy M. Ahern,Kristian Birchall,Michael J. Bond,Harparkash Kaur,Brendan W. Wren,Julien R. C. Bergeron,Lisa F. Dawson	2023	2
7	Fragment-based target screening as an empirical approach to prioritising targets: a case study on antibacterials Drug Discovery Today ·Peter Canning,Kristian Birchall,Catherine Kettleborough,Andy Merritt,P.J. Coombs	2020	7
8	Characterizing the binding and function of TARP γ8-selective AMPA receptor modulators Journal of Biological Chemistry ·Jan-Niklas Dohrke,Jake F. Watson,Kristian Birchall,Ingo H. Greger	2020	19
9	Potent bicyclic inhibitors of malarial cGMP-dependent protein kinase: approaches to combining improvements in cell potency, selectivity and structural novelty Bioorganic & Medicinal Chemistry Letters ·Jonathan M. Large,Kristian Birchall,Nathalie Bouloc,Andy Merritt,Ela Smiljanic-Hurley,Denise J. Tsagris,Mary C. Wheldon,Keith H. Ansell,P.J. Coombs,Catherine Kettleborough,David Whalley,Lindsay B. Stewart,Paul W. Bowyer,David A. Baker,Simon A. Osborne	2019	11
10	Trisubstituted thiazoles as potent and selective inhibitors of Plasmodium falciparum protein kinase G (PfPKG) Bioorganic & Medicinal Chemistry Letters ·Denise J. Tsagris,Kristian Birchall,Nathalie Bouloc,Jonathan M. Large,Andy Merritt,Ela Smiljanic-Hurley,Mary C. Wheldon,Keith H. Ansell,Catherine Kettleborough,David Whalley,Lindsay B. Stewart,Paul W. Bowyer,David A. Baker,Simon A. Osborne	2018	20
11	Discovery of potent and selective 5-azaindazole inhibitors of leucine-rich repeat kinase 2 (LRRK2) – Part 1 Bioorganic & Medicinal Chemistry Letters ·Joanne Osborne,Kristian Birchall,Denise J. Tsagris,Stephen J. Lewis,Ela Smiljanic-Hurley,Debra L. Taylor,Alison Levy,Dario R. Alessi,Edward G. McIver	2018	15
12	Design of the LifeArc Index Set and Retrospective Review of Its Performance: A Collection for Sharing SLAS DISCOVERY ·Kristian Birchall,Andy Merritt,Afrah Sattikar,Catherine Kettleborough,Barbara Saxty	2018	5
13	Design, Synthesis, and Testing of Potent, Selective Hepsin Inhibitors via Application of an Automated Closed-Loop Optimization Platform Journal of Medicinal Chemistry ·Shishir M. Pant,Amanda Mukonoweshuro,Bimbisar Desai,Manoj K. Ramjee,Christopher N. Selway,Gary J. Tarver,Adrian G. Wright,Kristian Birchall,Timothy M. Chapman,Topi A. Tervonen,Juha Klefström	2018	29
14	Potent inhibitors of malarial P. Falciparum protein kinase G: Improving the cell activity of a series of imidazopyridines Bioorganic & Medicinal Chemistry Letters ·Jonathan M. Large,Kristian Birchall,Nathalie Bouloc,Andy Merritt,Ela Smiljanic-Hurley,Denise J. Tsagris,Mary C. Wheldon,Keith H. Ansell,P.J. Coombs,Catherine Kettleborough,David Whalley,Lindsay B. Stewart,Paul W. Bowyer,David A. Baker,Simon A. Osborne	2018	14
15	Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay BMJ Open ·Juan Guzman,Dimitrios Evangelopoulos,Antima Gupta,Kristian Birchall,Solomon Mwaigwisya,Barbara Saxty,Timothy D. McHugh,Simon Gibbons,John P. Malkinson,Sanjib Bhakta	2013	68
16	Fragment-based hit identification: thinking in 3D Drug Discovery Today ·Andrew Morley,Angelo Pugliese,Kristian Birchall,Justin Bower,Paul E. Brennan,Nathan Brown,Tim Chapman,Martin J. Drysdale,Ian H. Gilbert,Swen Hoelder,Allan M. Jordan,Steven V. Ley,Andy Merritt,David S. Miller,Martin E. Swarbrick,Paul G. Wyatt	2013	129
17	Substituted imidazopyridazines are potent and selective inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) Bioorganic & Medicinal Chemistry Letters ·Timothy M. Chapman,Simon A. Osborne,Nathalie Bouloc,Jonathan M. Large,Claire Wallace,Kristian Birchall,Keith H. Ansell,Hayley M. Jones,Debra L. Taylor,Barbara Clough,Judith L. Green,Anthony A. Holder	2013	43
18	Synthesis and structure–activity relationships of a novel series of pyrimidines as potent inhibitors of TBK1/IKKε kinases Bioorganic & Medicinal Chemistry Letters ·Edward G. McIver,Justin S. Bryans,Kristian Birchall,Jasveen Chugh,T. F. Drake,Stephen J. Lewis,Joanne Osborne,Ela Smiljanic-Hurley,William Tsang,Ahmad M. Kamal,Alison Levy,Michelle Newman,Debra L. Taylor,J. Simon C. Arthur,Kristopher Clark,Philip Cohen	2012	36
19	Development of a differential scanning fluorimetry based high throughput screening assay for the discovery of affinity binders against an anthrax protein Journal of Pharmaceutical and Biomedical Analysis ·F.J. Sorrell,Gemma K. Greenwood,Kristian Birchall,Beining Chen	2010	24
20	Reduced Graphs and Their Applications in Chemoinformatics Methods in molecular biology ·Kristian Birchall,Valerie J. Gillet	2010	9

About Kristian Birchall

Kristian Birchall is a scholar working on Computational Theory and Mathematics, Pharmacology and Pharmacology, having authored 30 papers that have together received 733 indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (14 papers), Malaria Research and Control (6 papers), Machine Learning in Materials Science (4 papers), Microbial Natural Products and Biosynthesis (3 papers), Trypanosoma species research and implications (3 papers), Bioinformatics and Genomic Networks (3 papers), Protein Structure and Dynamics (2 papers) and Pharmacogenetics and Drug Metabolism (2 papers). The work is most often cited by research in Computational Theory and Mathematics (237 citations), Organic Chemistry (187 citations) and Molecular Biology (403 citations). Kristian Birchall has collaborated with scholars based in United Kingdom, Tanzania and Czechia. Frequent co-authors include Valerie J. Gillet, Andy Merritt, Gavin Harper, Stephen D. Pickett, Debra L. Taylor, Nathalie Bouloc, Timothy M. Chapman, Simon A. Osborne, Keith H. Ansell and Jonathan M. Large. Their work appears in journals such as Journal of Biological Chemistry, Bioinformatics and Scientific Reports.

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