Annette M.G. Dirac

5.3k citations

18 papers · 4.3k indexed · 2 hit papers · h-index 17

Co-authors: René Bernards Thijn R. Brummelkamp Sebastian Nijman Titia K. Sixma Mark P.A. Luna‐Vargas Arno Velds Alan D. D’Andrea Ron Kerkhoven
Topics: Ubiquitin and proteasome pathways (10 papers)HIV Research and Treatment (5 papers)RNA and protein synthesis mechanisms (4 papers)
Cited by: Molecular Biology Cancer Research Oncology
Journals: Nature Cell Nucleic Acids Research
Partner nations: Netherlands Denmark United States

In The Last Decade

Annette M.G. Dirac

18 papers receiving 4.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A Genomic and Functional Inventory of Deubiquitinating Enzymes

2005 1.5k citations Sebastian Nijman, Mark P.A. Luna‐Vargas et al. Cell profile →
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB

2003 778 citations Thijn R. Brummelkamp, Sebastian Nijman et al. Nature profile →

Peers

Countries citing papers authored by Annette M.G. Dirac

Since Specialization

Citations

This map shows the geographic impact of Annette M.G. Dirac's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Annette M.G. Dirac with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Annette M.G. Dirac more than expected).

Fields of papers citing papers by Annette M.G. Dirac

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Annette M.G. Dirac. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Annette M.G. Dirac. The network helps show where Annette M.G. Dirac may publish in the future.

Co-authorship network of co-authors of Annette M.G. Dirac

This figure shows the co-authorship network connecting the top 25 collaborators of Annette M.G. Dirac. A scholar is included among the top collaborators of Annette M.G. Dirac based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Annette M.G. Dirac. Annette M.G. Dirac is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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18 of 18 papers shown

#	Work	Indexed citations
1	A Functional Genomic Screen Identifies the Deubiquitinase USP11 as a Novel Transcriptional Regulator of ERα in Breast Cancer 2020 ·Cancer Research ·Lisa Dwane,Aisling O’Connor,Sudipto Das,Bruce Moran,Laoighse Mulrane,Adán Pinto-Fernández,(unknown),(unknown),Brenton Cavanagh,(unknown),Annette M.G. Dirac,Karin Jirström,Benedikt M. Kessler,Tríona Ní Chonghaile,René Bernards,William M. Gallagher,Darran P. O’Connor	25
2	Identification of F‐box only protein 7 as a negative regulator of NF‐kappaB signalling 2012 ·Journal of Cellular and Molecular Medicine ·Hendrik J. Kuiken,David A. Egan,Heike Laman,René Bernards,Roderick L. Beijersbergen,Annette M.G. Dirac	33
3	USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma 2012 ·Nature Medicine ·Pieter J.A. Eichhorn,Laura Rodón,Alba Gonzàlez-Juncà,Annette M.G. Dirac,Magüi Gili,Elena Martínez‐Sáez,Claudia Aura,Ignasi Barba,Vicente Peg,Aleix Prat,Isabel Cuartas,José Jiménez,David García‐Dorado,Juan Sahuquillo,René Bernards,José Baselga,Joan Seoane	332
4	Mechanism of USP7/HAUSP Activation by Its C-Terminal Ubiquitin-like Domain and Allosteric Regulation by GMP-Synthetase 2011 ·Molecular Cell ·Alex C. Faesen,Annette M.G. Dirac,Anitha Shanmugham,Huib Ovaa,Anastassis Perrakis,Titia K. Sixma	216
5	The Deubiquitinating Enzyme USP26 Is a Regulator of Androgen Receptor Signaling 2010 ·Molecular Cancer Research ·Annette M.G. Dirac,René Bernards	69
6	The Translation Initiation Factor 3f (eIF3f) Exhibits a Deubiquitinase Activity Regulating Notch Activation 2010 ·PLoS Biology ·Julien Moretti,Patricia Chastagner,Stefano Gastaldello,(unknown),Annette M.G. Dirac,René Bernards,Maria G. Masucci,Alain Israël,Christel Brou	72
7	An evaluation of the efficacy of topical application of salicylic acid for the treatment of familial cylindromatosis 2006 ·British Journal of Dermatology ·Hendrika M. Oosterkamp,H. Neering,Sebastian Nijman,Annette M.G. Dirac,W. J. Mooi,René Bernards,Thijn R. Brummelkamp	35
8	Bile Salt-Stimulated Lipase from Human Milk Binds DC-SIGN and Inhibits Human Immunodeficiency Virus Type 1 Transfer to CD4 ⁺ T Cells 2006 ·Antimicrobial Agents and Chemotherapy ·Marloes A. Naarding,Annette M.G. Dirac,Irene S. Ludwig,Dave Speijer,Susanne Lindquist,(unknown),(unknown),Teunis B. H. Geijtenbeek,Georgios Pollakis,Olle Hernell,William A. Paxton	62
9	The Deubiquitinating Enzyme USP1 Regulates the Fanconi Anemia Pathway 2005 ·Molecular Cell ·Sebastian Nijman,Tony T. Huang,Annette M.G. Dirac,Thijn R. Brummelkamp,Ron Kerkhoven,Alan D. D’Andrea,René Bernards	458
10	A Genomic and Functional Inventory of Deubiquitinating Enzymesbreakdown → 2005 ·Cell ·Sebastian Nijman,Mark P.A. Luna‐Vargas,Arno Velds,Thijn R. Brummelkamp,Annette M.G. Dirac,Titia K. Sixma,René Bernards	1514
11	Functional Annotation of Deubiquitinating Enzymes Using RNA Interference 2005 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Annette M.G. Dirac,Sebastian Nijman,Thijn R. Brummelkamp,René Bernards	7
12	Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κBbreakdown → 2003 ·Nature ·Thijn R. Brummelkamp,Sebastian Nijman,Annette M.G. Dirac,René Bernards	778
13	Reversal of Senescence in Mouse Fibroblasts through Lentiviral Suppression of p53 2003 ·Journal of Biological Chemistry ·Annette M.G. Dirac,René Bernards	201
14	Regulated HIV-2 RNA dimerization by means of alternative RNA conformations 2002 ·Nucleic Acids Research ·Annette M.G. Dirac	44
15	Requirements for RNA heterodimerization of the human immunodeficiency virus type 1 (HIV-1) and HIV-2 genomes 2002 ·Journal of General Virology ·Annette M.G. Dirac,Hendrik Huthoff,Jørgen Kjems,Ben Berkhout	22
16	Mapping DNA‐binding sites of HIV‐1 integrase by protein footprinting 2001 ·European Journal of Biochemistry ·Annette M.G. Dirac,Jørgen Kjems	29
17	The Dimer Initiation Site Hairpin Mediates Dimerization of the Human Immunodeficiency Virus, Type 2 RNA Genome 2001 ·Journal of Biological Chemistry ·Annette M.G. Dirac,Hendrik Huthoff,Jørgen Kjems,Ben Berkhout	40
18	Elongator, a Multisubunit Component of a Novel RNA Polymerase II Holoenzyme for Transcriptional Elongation 1999 ·Molecular Cell ·Gabriel Otero,Jane Fellows,Yang Li,Thérèse de Bizemont,Annette M.G. Dirac,Claes M. Gustafsson,Hediye Erdjument‐Bromage,Paul Tempst,Jesper Q. Svejstrup	411

About Annette M.G. Dirac

Annette M.G. Dirac is a scholar working on Virology, Cancer Research and Molecular Biology, having authored 18 papers that have together received 4.3k indexed citations. Recurring topics across this work include Ubiquitin and proteasome pathways (10 papers), HIV Research and Treatment (5 papers) and RNA and protein synthesis mechanisms (4 papers). The work is most often cited by research in Molecular Biology (3.7k citations), Cancer Research (811 citations) and Oncology (1.2k citations). Annette M.G. Dirac has collaborated with scholars based in Netherlands, Denmark and United States. Frequent co-authors include René Bernards, Thijn R. Brummelkamp, Sebastian Nijman, Titia K. Sixma, Mark P.A. Luna‐Vargas, Arno Velds, Alan D. D’Andrea, Ron Kerkhoven, Tony T. Huang and Hediye Erdjument‐Bromage. Their work appears in journals such as Nature, Cell and Nucleic Acids Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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