Alain Israël

23.7k citations

126 papers · 17.4k indexed · 7 hit papers · h-index 63

Molecular Biology top 0.5%
Immunology top 0.1%
Cancer Research top 0.05%
Oncology top 0.5%
Genetics top 1%

Co-authors: Philippe Kourilsky Christel Brou Frédérique Logeat Gilles Courtois O. Le Bail Robert Weil Volker Blank Sophie Jarriault
Topics: NF-κB Signaling Pathways (63 papers)Immune Response and Inflammation (34 papers)interferon and immune responses (23 papers)
Cited by: Cancer Research Immunology Molecular Biology
Journals: Nature Cell Proceedings of the National Academy of Sciences
Partner nations: France United States Japan

In The Last Decade

Alain Israël

126 papers receiving 17.1k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Signalling downstream of activated mammalian Notch

1995 1.2k citations Sophie Jarriault, Christel Brou et al. Nature profile →
Complementation Cloning of NEMO, a Component of the IκB Kinase Complex Essential for NF-κB Activation

1998 931 citations Gilles Courtois, Christine Bessia et al. profile →
A Novel Proteolytic Cleavage Involved in Notch Signaling

2000 869 citations Christel Brou, Frédérique Logeat et al. Molecular Cell profile →
The tumour suppressor CYLD negatively regulates NF-κB signalling by deubiquitination

2003 830 citations Andrew Kovalenko, Christine Chable-Bessia et al. Nature profile →
The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product

1990 829 citations Mark W. Kieran, Frédérique Logeat et al. profile →
The IKK Complex, a Central Regulator of NF- B Activation

2009 669 citations Alain Israël profile →
The Notch1 receptor is cleaved constitutively by a furin-like convertase

1998 569 citations Frédérique Logeat, Christine Bessia et al. profile →

Peers

Countries citing papers authored by Alain Israël

Since Specialization

Citations

This map shows the geographic impact of Alain Israël's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alain Israël with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alain Israël more than expected).

Fields of papers citing papers by Alain Israël

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alain Israël. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alain Israël. The network helps show where Alain Israël may publish in the future.

Co-authorship network of co-authors of Alain Israël

This figure shows the co-authorship network connecting the top 25 collaborators of Alain Israël. A scholar is included among the top collaborators of Alain Israël based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alain Israël. Alain Israël is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Two NEMO-like Ubiquitin-Binding Domains in CEP55 Differently Regulate Cytokinesis 2019 ·iScience ·(unknown),(unknown),(unknown),(unknown),Marine Charpentier,(unknown),Robert Weil,Alain Israël,Emmanuel Laplantine,Fabrice Agou	9
2	Regrowing the Adult Brain: NF-κB Controls Functional Circuit Formation and Tissue Homeostasis in the Dentate Gyrus 2012 ·PLoS ONE ·(unknown),Jens C. Schwamborn,Patrick Lüningschrör,Peter Heimann,(unknown),Hendrikje Werner,(unknown),Andreas W. Püschel,Sylvie Mémet,Rolf Heumann,Alain Israël,Christian Kaltschmidt,Barbara Kaltschmidt	58
3	DARPin-Assisted Crystallography of the CC2-LZ Domain of NEMO Reveals a Coupling between Dimerization and Ubiquitin Binding 2009 ·Journal of Molecular Biology ·Olivera Grubisha,M. Kamińska,S. Duquerroy,(unknown),Florence Cordier,Ahmed Haouz,Bertrand Raynal,Jeanne Chiaravalli,Muriel Delepierre,Alain Israël,Michel Véron,Fabrice Agou	34
4	Inhibition of NEMO, the regulatory subunit of the IKK complex, induces apoptosis in high-risk myelodysplastic syndrome and acute myeloid leukemia 2006 ·Oncogene ·(unknown),Claire Fabre,Thomas Braun,J. Grosjean,Lionel Adès,Fabrice Agou,Ezgi Tasdemir,Simone Boehrer,Alain Israël,M. Véron,Pierre Fenaux,Guido Kroemer	40
5	Activation of NF-κB in the mouse spinal cord following sciatic nerve transection 2005 ·Experimental Brain Research ·Glen Pollock,Keith R. Pennypacker,Sylvie Mémet,Alain Israël,Samuel Saporta	36
6	Inhibition of NF-κB Activation by Peptides Targeting NF-κB Essential Modulator (NEMO) Oligomerization 2004 ·Journal of Biological Chemistry ·Fabrice Agou,Gilles Courtois,Jeanne Chiaravalli,Françoise Baleux,Yves‐Marie Coïc,François Traincard,Alain Israël,Michel Véron	52
7	The tumour suppressor CYLD negatively regulates NF-κB signalling by deubiquitinationbreakdown → 2003 ·Nature ·Andrew Kovalenko,Christine Chable-Bessia,Giuseppina Cantarella,Alain Israël,David Wallach,Gilles Courtois	830
8	From Calcium to NF-κB Signaling Pathways in Neurons 2003 ·Molecular and Cellular Biology ·Alain Lilienbaum,Alain Israël	197
9	Mature T Cells Depend on Signaling through the IKK Complex 2003 ·Immunity ·Marc Schmidt‐Supprian,Gilles Courtois,Jane Tian,Anthony J. Coyle,Alain Israël,Klaus Rajewsky,Manolis Pasparakis	185
10	TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2 2002 ·Nature ·Manolis Pasparakis,Gilles Courtois,Martin Hafner,Marc Schmidt‐Supprian,Arianna Nenci,Atiye Toksoy,Monika Krampert,Matthias Goebeler,R. Gillitzer,Alain Israël,Thomas Krieg,Klaus Rajewsky,Ingo Haase	399
11	NEMO/IKKγ-Deficient Mice Model Incontinentia Pigmenti 2000 ·Molecular Cell ·Marc Schmidt‐Supprian,Wilhelm Bloch,Gilles Courtois,Klaus Addicks,Alain Israël,Klaus Rajewsky,Manolis Pasparakis	365
12	A Novel Proteolytic Cleavage Involved in Notch Signalingbreakdown → 2000 ·Molecular Cell ·Christel Brou,Frédérique Logeat,Neetu Gupta,Christine Bessia,(unknown),John R. Doedens,Ana Cumano,Pascal Roux,Roy A. Black,Alain Israël	869
13	Delta-1 Activation of Notch-1 Signaling Results in HES-1 Transactivation 1998 ·Molecular and Cellular Biology ·Sophie Jarriault,O. Le Bail,Estelle Hirsinger,Olivier Pourquié,Frédérique Logeat,(unknown),Christel Brou,Nabil G. Seidah,Alain Israël	284
14	N- and C-Terminal Sequences Control Degradation of MAD3/IκBα in Response to Inducers of NF-κB Activity 1995 ·Molecular and Cellular Biology ·Simon T. Whiteside,Mary K. Ernst,(unknown),Christine Laurent‐Winter,Nancy R. Rice,Alain Israël	214
15	Signalling downstream of activated mammalian Notchbreakdown → 1995 ·Nature ·Sophie Jarriault,Christel Brou,Frédérique Logeat,Eric H. Schroeter,Raphael Kopan,Alain Israël	1190
16	Genomic structure and chromosomal localization of processed pseudogenes for human RBP-Jk 1994 ·The Japanese Journal of Human Genetics ·Mingdi Zhang,Xiaoou Tang,(unknown),Frédérique Logeat,Alain Israël,Shinichi Kondo,Kailai Sun,Kazushige Yokoyama	3
17	Promoter analysis of the gene encoding the I kappa B-alpha/MAD3 inhibitor of NF-kappa B: positive regulation by members of the rel/NF-kappa B family. 1993 ·The EMBO Journal ·O. Le Bail,Ruth Schmidt‐Ullrich,Alain Israël	295
18	Comparison of the promoter regions of H-2K^band H-2K^bm1class I MHC genes 1990 ·Nucleic Acids Research ·Kazuo Ozawa,(unknown),Issay Kitabayashi,(unknown),Eiichi Soeda,Alain Israël,Gabriel Gachelin,Kazushige Yokoyama	5
19	Two purified factors bind to the same sequence in the enhancer of mouse MHC class I genes: one of them is a positive regulator induced upon differentiation of teratocarcinoma cells 1989 ·Nucleic Acids Research ·Alain Israël,Osamu Yano,(unknown),Mark W. Kieran,Philippe Kourilsky	58
20	Hormonally Mediated Negative Regulation of Human Pro-Opiomelanocortin Gene Expression after Transfection into Mouse L Cells 1985 ·Molecular and Cellular Biology ·Alain Israël,Stanley N. Cohen	8

About Alain Israël

Alain Israël is a scholar working on Cancer Research, Immunology and Molecular Biology, having authored 126 papers that have together received 17.4k indexed citations. Recurring topics across this work include NF-κB Signaling Pathways (63 papers), Immune Response and Inflammation (34 papers) and interferon and immune responses (23 papers). The work is most often cited by research in Cancer Research (6.4k citations), Immunology (7.2k citations) and Molecular Biology (9.7k citations). Alain Israël has collaborated with scholars based in France, United States and Japan. Frequent co-authors include Philippe Kourilsky, Christel Brou, Frédérique Logeat, Gilles Courtois, O. Le Bail, Robert Weil, Volker Blank, Sophie Jarriault, Christine Bessia and Simon T. Whiteside. Their work appears in journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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