Andrew G. Hughson

6.9k citations

64 papers · 4.4k indexed · 2 hit papers · h-index 33

Co-authors: Byron Caughey Christina D. Orrú Bradley R. Groveman Gregory J. Raymond Valerie L. Sim Richard Race Jay R. Silveira Gianluigi Zanusso
Topics: Prion Diseases and Protein Misfolding (52 papers)Neurological diseases and metabolism (18 papers)Trace Elements in Health (18 papers)
Cited by: Neurology Nutrition and Dietetics
Journals: Nature New England Journal of Medicine Proceedings of the National Academy of Sciences
Partner nations: United States Italy Japan

In The Last Decade

Andrew G. Hughson

62 papers receiving 4.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The most infectious prion protein particles

2005 717 citations Jay R. Silveira, Gregory J. Raymond et al. Nature profile →
Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC

2018 285 citations Bradley R. Groveman, Christina D. Orrú et al. Acta Neuropathologica Communications profile →

Peers

Countries citing papers authored by Andrew G. Hughson

Since Specialization

Citations

This map shows the geographic impact of Andrew G. Hughson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Andrew G. Hughson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Andrew G. Hughson more than expected).

Fields of papers citing papers by Andrew G. Hughson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Andrew G. Hughson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Andrew G. Hughson. The network helps show where Andrew G. Hughson may publish in the future.

Co-authorship network of co-authors of Andrew G. Hughson

This figure shows the co-authorship network connecting the top 25 collaborators of Andrew G. Hughson. A scholar is included among the top collaborators of Andrew G. Hughson based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Andrew G. Hughson. Andrew G. Hughson is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	A same day α-synuclein RT-QuIC seed amplification assay for synucleinopathy biospecimens 2025 ·PubMed ·Sabiha Parveen,Parvez Alam,Christina D. Orrú,Sarah Vascellari,Andrew G. Hughson,Wen‐Quan Zou,Thomas G. Beach,Geidy E. Serrano,David S. Goldstein,Bernardino Ghetti,Giovanni Cossu,(unknown),(unknown),Byron Caughey	4
2	Prions and protein aggregates as pathogens, self-propagating structures, biomarkers, and therapeutic targets 2025 ·Microbiology and Molecular Biology Reviews ·Byron Caughey,Efrosini Artikis,(unknown),Christina D. Orrú,Parvez Alam,Sabiha Parveen,Samantha J. King,(unknown),Andrew G. Hughson,Suzette A. Priola	0
3	Cryo-EM structure of a natural prion: chronic wasting disease fibrils from deer 2024 ·Acta Neuropathologica ·Parvez Alam,Forrest Hoyt,Efrosini Artikis,(unknown),Andrew G. Hughson,Cindi L. Schwartz,Kent Barbian,Michael W. Miller,Brent Race,Byron Caughey	11
4	α-Synuclein seeding activity in duodenum biopsies from Parkinson’s disease patients 2023 ·PLoS Pathogens ·Sarah Vascellari,Christina D. Orrú,Bradley R. Groveman,Sabiha Parveen,Giuseppe Fenu,(unknown),(unknown),Giulia Serra,Valentina Oppo,Daniela Murgia,Andrea Perra,Fabrizio Angius,Andrew G. Hughson,Cathryn L. Haigh,Aldo Manzin,Giovanni Cossu,Byron Caughey	15
5	Sporadic Creutzfeldt–Jakob disease infected human cerebral organoids retain the original human brain subtype features following transmission to humanized transgenic mice 2023 ·Acta Neuropathologica Communications ·Bradley R. Groveman,Brent Race,Simote T. Foliaki,Katie Williams,Andrew G. Hughson,(unknown),Gianluigi Zanusso,Cathryn L. Haigh	10
6	Tau seeds occur before earliest Alzheimer’s changes and are prevalent across neurodegenerative diseases 2023 ·Acta Neuropathologica ·Matteo Manca,(unknown),(unknown),Mikayla L. Huntley,(unknown),Christina D. Orrú,Andrew G. Hughson,(unknown),Jing Zhang,Curtis Tatsuoka,Xiongwei Zhu,Annie Hiniker,David G. Coughlin,Douglas Galasko,Allison Kraus	14
7	Efficacy of Wex-cide 128 disinfectant against multiple prion strains 2023 ·PLoS ONE ·(unknown),Bradley R. Groveman,Andrew G. Hughson,T. TURNER THOMAS,(unknown),Suzette A. Priola,Bruce Chesebro,Brent Race	5
8	Performance of αSynuclein RT-QuIC in relation to neuropathological staging of Lewy body disease 2022 ·Acta Neuropathologica Communications ·Sara Hall,Christina D. Orrú,Geidy E. Serrano,Douglas Galasko,Andrew G. Hughson,Bradley R. Groveman,Charles H. Adler,Thomas G. Beach,Byron Caughey,Oskar Hansson	78
9	Cryo-EM structure of anchorless RML prion reveals variations in shared motifs between distinct strains 2022 ·Nature Communications ·Forrest Hoyt,(unknown),Efrosini Artikis,Cindi L. Schwartz,Bryan Hansen,Kunpeng Li,Andrew G. Hughson,Matteo Manca,(unknown),Gregory J. Raymond,Brent Race,Gerald S. Baron,Byron Caughey,Allison Kraus	61
10	Second passage experiments of chronic wasting disease in transgenic mice overexpressing human prion protein 2022 ·Veterinary Research ·Brent Race,(unknown),Katie Williams,James F. Striebel,Andrew G. Hughson,Bruce Chesebro	7
11	High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson’s disease 2021 ·Acta Neuropathologica Communications ·Marco J. Russo,Christina D. Orrú,Luis Concha‐Marambio,(unknown),Bradley R. Groveman,Carly M. Farris,(unknown),Andrew G. Hughson,(unknown),Chelsea Caspell‐Garcia,Christopher S. Coffey,J Mollon,Samantha J. Hutten,Kalpana Merchant,Roland G. Heym,Claudio Soto,Byron Caughey,Un Jung Kang	137
12	Familial human prion diseases associated with prion protein mutations Y226X and G131V are transmissible to transgenic mice expressing human prion protein 2018 ·Acta Neuropathologica Communications ·Brent Race,Katie Williams,Andrew G. Hughson,Casper Jansen,Piero Parchi,Annemieke J.M. Rozemüller,Bruce Chesebro	16
13	Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuICbreakdown → 2018 ·Acta Neuropathologica Communications ·Bradley R. Groveman,Christina D. Orrú,Andrew G. Hughson,Lynne D. Raymond,Gianluigi Zanusso,Bernardino Ghetti,Katrina J. Campbell,Jiri Safar,Douglas Galasko,Byron Caughey	285
14	Ultrasensitive RT-QuIC Seed Amplification Assays for Disease-Associated Tau, α-Synuclein, and Prion Aggregates 2018 ·Methods in molecular biology ·Eri Saijo,Bradley R. Groveman,Allison Kraus,Michael A. Metrick,Christina D. Orrú,Andrew G. Hughson,Byron Caughey	54
15	A Promising Antiprion Trimethoxychalcone Binds to the Globular Domain of the Cellular Prion Protein and Changes Its Cellular Location 2017 ·Antimicrobial Agents and Chemotherapy ·Natalia Ferreira,(unknown),Andrew G. Hughson,(unknown),(unknown),(unknown),Jason R. Hollister,(unknown),(unknown),Alessandra Mendonça Teles de Souza,Maria Letícia de Castro Barbosa,Flávio Alves Lara,Rodrigo A. P. Martins,Byron Caughey,Yraima Cordeiro	14
16	Amplified Detection of Prions and Other Amyloids by RT-QuIC in Diagnostics and the Evaluation of Therapeutics and Disinfectants 2017 ·Progress in molecular biology and translational science ·Byron Caughey,Christina D. Orrú,Bradley R. Groveman,Andrew G. Hughson,Matteo Manca,Lynne D. Raymond,Gregory J. Raymond,Brent Race,Eri Saijo,Allison Kraus	16
17	Bank Vole Prion Protein As an Apparently Universal Substrate for RT-QuIC-Based Detection and Discrimination of Prion Strains 2015 ·PMC ·Christina D. Orrú,Bradley R. Groveman,Lynne D. Raymond,Andrew G. Hughson,Romolo Nonno,Wen‐Quan Zou,Bernardino Ghetti,Pierluigi Gambetti,Byron Caughey	1
18	Prion Seeding Activities of Mouse Scrapie Strains with Divergent PrPSc Protease Sensitivities and Amyloid Plaque Content Using RT-QuIC and eQuIC 2012 ·PLoS ONE ·Sarah Vascellari,Christina D. Orrú,Andrew G. Hughson,Declan King,Rona Barron,Jason M. Wilham,Gerald S. Baron,Brent Race,Alessandra Pani,Byron Caughey	52
19	New generation QuIC assays for prion seeding activity 2012 ·Prion ·Christina D. Orrú,Jason M. Wilham,Sarah Vascellari,Andrew G. Hughson,Byron Caughey	79
20	The most infectious prion protein particlesbreakdown → 2005 ·Nature ·Jay R. Silveira,Gregory J. Raymond,Andrew G. Hughson,Richard Race,Valerie L. Sim,Stanley F. Hayes,Byron Caughey	717

About Andrew G. Hughson

Andrew G. Hughson is a scholar working on Neurology, Nutrition and Dietetics and Neurology, having authored 64 papers that have together received 4.4k indexed citations. Recurring topics across this work include Prion Diseases and Protein Misfolding (52 papers), Neurological diseases and metabolism (18 papers) and Trace Elements in Health (18 papers). The work is most often cited by research in Neurology (1.6k citations), Neurology (1.1k citations) and Nutrition and Dietetics (903 citations). Andrew G. Hughson has collaborated with scholars based in United States, Italy and Japan. Frequent co-authors include Byron Caughey, Christina D. Orrú, Bradley R. Groveman, Gregory J. Raymond, Valerie L. Sim, Richard Race, Jay R. Silveira, Gianluigi Zanusso, Stanley F. Hayes and Lynne D. Raymond. Their work appears in journals such as Nature, New England Journal of Medicine and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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