Andrew G. Hughson

6.9k citations

64 papers · 4.4k indexed · 2 hit papers · h-index 33

Neurology top 0.2%
- Neurological diseases and metabolism 18
- Parkinson's Disease Mechanisms and Treatments 9
- Neurological disorders and treatments 8
- Alcoholism and Thiamine Deficiency 3
Neurology top 1%
- Neurological diseases and metabolism 18
- Parkinson's Disease Mechanisms and Treatments 9
- Neurological disorders and treatments 8
- Alcoholism and Thiamine Deficiency 3
Nutrition and Dietetics top 1%
- Trace Elements in Health 18
Molecular Biology top 2%
- Prion Diseases and Protein Misfolding 52
Physiology top 2%
- Alzheimer's disease research and treatments 8
Infectious Diseases
- Infectious Encephalopathies and Encephalitis 6

Co-authors: Byron Caughey Christina D. Orrú Bradley R. Groveman Gregory J. Raymond Valerie L. Sim Richard Race Jay R. Silveira Gianluigi Zanusso
Cited by: Neurology Nutrition and Dietetics
Journals: Nature (1 paper)New England Journal of Medicine (1 paper)Proceedings of the National Academy of Sciences (2 papers)
Partner nations: United States Italy Japan

In The Last Decade

Andrew G. Hughson

62 papers receiving 4.3k citations

Hit Papers

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Peers

Countries citing papers authored by Andrew G. Hughson

Since Specialization

Citations

This map shows the geographic impact of Andrew G. Hughson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Andrew G. Hughson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Andrew G. Hughson more than expected).

Fields of papers citing papers by Andrew G. Hughson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Andrew G. Hughson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Andrew G. Hughson. The network helps show where Andrew G. Hughson may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Andrew G. Hughson, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Andrew G. Hughson Line = papers co-authored together Andrew G. Hughson links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	A same day α-synuclein RT-QuIC seed amplification assay for synucleinopathy biospecimens PubMed ·Sabiha Parveen,Parvez Alam,Christina D. Orrú,Sarah Vascellari,Andrew G. Hughson,Wen‐Quan Zou,Thomas G. Beach,Geidy E. Serrano,David S. Goldstein,Bernardino Ghetti,Giovanni Cossu,Giada Pisano,Beatrice Pinna,Byron Caughey	2025	4
2	Prions and protein aggregates as pathogens, self-propagating structures, biomarkers, and therapeutic targets Microbiology and Molecular Biology Reviews ·Byron Caughey,Efrosini Artikis,Daniel Shoup,Christina D. Orrú,Parvez Alam,Sabiha Parveen,Samantha J. King,Jakub Soukup,Andrew G. Hughson,Suzette A. Priola	2025	0
3	Cryo-EM structure of a natural prion: chronic wasting disease fibrils from deer Acta Neuropathologica ·Parvez Alam,Forrest Hoyt,Efrosini Artikis,Jakub Soukup,Andrew G. Hughson,Cindi L. Schwartz,Kent Barbian,Michael W. Miller,Brent Race,Byron Caughey	2024	11
4	α-Synuclein seeding activity in duodenum biopsies from Parkinson’s disease patients PLoS Pathogens ·Sarah Vascellari,Christina D. Orrú,Bradley R. Groveman,Sabiha Parveen,Giuseppe Fenu,Giada Pisano,Giuseppe Piga,Giulia Serra,Valentina Oppo,Daniela Murgia,Andrea Perra,Fabrizio Angius,Andrew G. Hughson,Cathryn L. Haigh,Aldo Manzin,Giovanni Cossu,Byron Caughey	2023	15
5	Sporadic Creutzfeldt–Jakob disease infected human cerebral organoids retain the original human brain subtype features following transmission to humanized transgenic mice Acta Neuropathologica Communications ·Bradley R. Groveman,Brent Race,Simote T. Foliaki,Katie Williams,Andrew G. Hughson,Chase Baune,Gianluigi Zanusso,Cathryn L. Haigh	2023	10
6	Tau seeds occur before earliest Alzheimer’s changes and are prevalent across neurodegenerative diseases Acta Neuropathologica ·Matteo Manca,Heidi G. Standke,Danielle F. Browne,Mikayla L. Huntley,Olivia R. Thomas,Christina D. Orrú,Andrew G. Hughson,Yongya Kim,Jing Zhang,Curtis Tatsuoka,Xiongwei Zhu,Annie Hiniker,David G. Coughlin,Douglas Galasko,Allison Kraus	2023	14
7	Efficacy of Wex-cide 128 disinfectant against multiple prion strains PLoS ONE ·Chase Baune,Bradley R. Groveman,Andrew G. Hughson,T. TURNER THOMAS,Barry Twardoski,Suzette A. Priola,Bruce Chesebro,Brent Race	2023	5
8	Performance of αSynuclein RT-QuIC in relation to neuropathological staging of Lewy body disease Acta Neuropathologica Communications ·Sara Hall,Christina D. Orrú,Geidy E. Serrano,Douglas Galasko,Andrew G. Hughson,Bradley R. Groveman,Charles H. Adler,Thomas G. Beach,Byron Caughey,Oskar Hansson	2022	78
9	Cryo-EM structure of anchorless RML prion reveals variations in shared motifs between distinct strains Nature Communications ·Forrest Hoyt,Heidi G. Standke,Efrosini Artikis,Cindi L. Schwartz,Bryan Hansen,Kunpeng Li,Andrew G. Hughson,Matteo Manca,Olivia R. Thomas,Gregory J. Raymond,Brent Race,Gerald S. Baron,Byron Caughey,Allison Kraus	2022	61
10	Second passage experiments of chronic wasting disease in transgenic mice overexpressing human prion protein Veterinary Research ·Brent Race,Chase Baune,Katie Williams,James F. Striebel,Andrew G. Hughson,Bruce Chesebro	2022	7
11	High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson’s disease Acta Neuropathologica Communications ·Marco J. Russo,Christina D. Orrú,Luis Concha‐Marambio,Simone Giaisi,Bradley R. Groveman,Carly M. Farris,Bret Holguin,Andrew G. Hughson,David-Erick Lafontant,Chelsea Caspell‐Garcia,Christopher S. Coffey,J Mollon,Samantha J. Hutten,Kalpana Merchant,Roland G. Heym,Claudio Soto,Byron Caughey,Un Jung Kang	2021	137
12	Familial human prion diseases associated with prion protein mutations Y226X and G131V are transmissible to transgenic mice expressing human prion protein Acta Neuropathologica Communications ·Brent Race,Katie Williams,Andrew G. Hughson,Casper Jansen,Piero Parchi,Annemieke J.M. Rozemüller,Bruce Chesebro	2018	16
13	Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuICbreakdown → Acta Neuropathologica Communications ·Bradley R. Groveman,Christina D. Orrú,Andrew G. Hughson,Lynne D. Raymond,Gianluigi Zanusso,Bernardino Ghetti,Katrina J. Campbell,Jiri Safar,Douglas Galasko,Byron Caughey	2018	285
14	Ultrasensitive RT-QuIC Seed Amplification Assays for Disease-Associated Tau, α-Synuclein, and Prion Aggregates Methods in molecular biology ·Eri Saijo,Bradley R. Groveman,Allison Kraus,Michael A. Metrick,Christina D. Orrú,Andrew G. Hughson,Byron Caughey	2018	54
15	A Promising Antiprion Trimethoxychalcone Binds to the Globular Domain of the Cellular Prion Protein and Changes Its Cellular Location Antimicrobial Agents and Chemotherapy ·Natalia Ferreira,Lucas M. Ascari,Andrew G. Hughson,Gabriel R. Cavalheiro,Carolina F. Goes,Paula Fernandes,Jason R. Hollister,Raissa Alves da Conceição,Daiana Silveira da Silva,Alessandra Mendonça Teles de Souza,Maria Letícia de Castro Barbosa,Flávio Alves Lara,Rodrigo A. P. Martins,Byron Caughey,Yraima Cordeiro	2017	14
16	Amplified Detection of Prions and Other Amyloids by RT-QuIC in Diagnostics and the Evaluation of Therapeutics and Disinfectants Progress in molecular biology and translational science ·Byron Caughey,Christina D. Orrú,Bradley R. Groveman,Andrew G. Hughson,Matteo Manca,Lynne D. Raymond,Gregory J. Raymond,Brent Race,Eri Saijo,Allison Kraus	2017	16
17	Bank Vole Prion Protein As an Apparently Universal Substrate for RT-QuIC-Based Detection and Discrimination of Prion Strains PMC ·Christina D. Orrú,Bradley R. Groveman,Lynne D. Raymond,Andrew G. Hughson,Romolo Nonno,Wen‐Quan Zou,Bernardino Ghetti,Pierluigi Gambetti,Byron Caughey	2015	1
18	Prion Seeding Activities of Mouse Scrapie Strains with Divergent PrPSc Protease Sensitivities and Amyloid Plaque Content Using RT-QuIC and eQuIC PLoS ONE ·Sarah Vascellari,Christina D. Orrú,Andrew G. Hughson,Declan King,Rona Barron,Jason M. Wilham,Gerald S. Baron,Brent Race,Alessandra Pani,Byron Caughey	2012	52
19	New generation QuIC assays for prion seeding activity Prion ·Christina D. Orrú,Jason M. Wilham,Sarah Vascellari,Andrew G. Hughson,Byron Caughey	2012	79
20	The most infectious prion protein particlesbreakdown → Nature ·Jay R. Silveira,Gregory J. Raymond,Andrew G. Hughson,Richard Race,Valerie L. Sim,Stanley F. Hayes,Byron Caughey	2005	717

About Andrew G. Hughson

Andrew G. Hughson is a scholar working on Neurology, Nutrition and Dietetics and Neurology, having authored 64 papers that have together received 4.4k indexed citations. Recurring topics across this work include Prion Diseases and Protein Misfolding (52 papers), Neurological diseases and metabolism (18 papers), Trace Elements in Health (18 papers), Parkinson's Disease Mechanisms and Treatments (9 papers), Alzheimer's disease research and treatments (8 papers), Neurological disorders and treatments (8 papers), Infectious Encephalopathies and Encephalitis (6 papers) and Alcoholism and Thiamine Deficiency (3 papers). The work is most often cited by research in Neurology (1.6k citations), Neurology (1.1k citations) and Nutrition and Dietetics (903 citations). Andrew G. Hughson has collaborated with scholars based in United States, Italy and Japan. Frequent co-authors include Byron Caughey, Christina D. Orrú, Bradley R. Groveman, Gregory J. Raymond, Valerie L. Sim, Richard Race, Jay R. Silveira, Gianluigi Zanusso, Stanley F. Hayes and Lynne D. Raymond. Their work appears in journals such as Nature, New England Journal of Medicine and Proceedings of the National Academy of Sciences.

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