Lauri A. Aaltonen

70.9k citations

284 papers · 22.9k indexed · 8 hit papers · h-index 75

Pathology and Forensic Medicine top 0.01%
Oncology top 0.05%
Molecular Biology top 0.5%
Cancer Research top 0.05%
Surgery top 0.5%

Co-authors: Jukka‐Pekka Mecklin Heikki Järvinen Albert de la Chapelle Reijo Salovaara Païvi Peltomäki Markku Aarnio Minna Nyström Eero Pukkala
Topics: Genetic factors in colorectal cancer (148 papers)Cancer Genomics and Diagnostics (56 papers)Colorectal Cancer Treatments and Studies (52 papers)
Cited by: Pathology and Forensic Medicine Cancer Research Oncology
Journals: Science New England Journal of Medicine Proceedings of the National Academy of Sciences
Partner nations: Finland United States United Kingdom

In The Last Decade

Lauri A. Aaltonen

278 papers receiving 22.4k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer

2000 926 citations Heikki Järvinen, Markku Aarnio et al. profile →
Cancer risk in mutation carriers of DNA-mismatch-repair genes

1999 889 citations Markku Aarnio, Risto Sankila et al. International Journal of Cancer profile →
Incidence of Hereditary Nonpolyposis Colorectal Cancer and the Feasibility of Molecular Screening for the Disease

1998 856 citations Lauri A. Aaltonen, Reijo Salovaara et al. profile →
Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history.

1993 673 citations Païvi Peltomäki, Lauri A. Aaltonen et al. PubMed profile →
Mutations in the SMAD4/DPC4 Gene in Juvenile Polyposis

1998 668 citations Heikki Järvinen, Pertti Sistonen et al. Science profile →
Multiple Colorectal Adenomas, Classic Adenomatous Polyposis, and Germ-Line Mutations inMYH

2003 596 citations Oliver M. Sieber, Lara Lipton et al. profile →
Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients.

1994 510 citations Lauri A. Aaltonen, Païvi Peltomäki et al. PubMed profile →
MED12 , the Mediator Complex Subunit 12 Gene, Is Mutated at High Frequency in Uterine Leiomyomas

2011 470 citations Netta Mäkinen, Miika Mehine et al. Science profile →

Peers

Countries citing papers authored by Lauri A. Aaltonen

Since Specialization

Citations

This map shows the geographic impact of Lauri A. Aaltonen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lauri A. Aaltonen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lauri A. Aaltonen more than expected).

Fields of papers citing papers by Lauri A. Aaltonen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lauri A. Aaltonen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lauri A. Aaltonen. The network helps show where Lauri A. Aaltonen may publish in the future.

Co-authorship network of co-authors of Lauri A. Aaltonen

This figure shows the co-authorship network connecting the top 25 collaborators of Lauri A. Aaltonen. A scholar is included among the top collaborators of Lauri A. Aaltonen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lauri A. Aaltonen. Lauri A. Aaltonen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Non-stem cell lineages as an alternative origin of intestinal tumorigenesis in the context of inflammation 2024 ·Nature Genetics ·(unknown),Rosalie Joosten,Mark R. Schmitt,Niko Välimäki,Andrea Sacchetti,Kristiina Rajamäki,Jiahn Choi,(unknown),(unknown),(unknown),Thierry van den Bosch,Daniëlle Seinstra,Annemarie C. de Vries,Michail Doukas,Leonard H. Augenlicht,Lauri A. Aaltonen,Riccardo Fodde	17
2	Vitamin C boosts DNA demethylation in TET2 germline mutation carriers 2023 ·Clinical Epigenetics ·Aurora Taira,Kimmo Palin,Anna Kuosmanen,Niko Välimäki,Outi Kuittinen,Outi Kuismin,Eevi Kaasinen,Kristiina Rajamäki,Lauri A. Aaltonen	16
3	Genetic and Epigenetic Characterization of Growth Hormone–Secreting Pituitary Tumors 2019 ·Molecular Cancer Research ·Niko Välimäki,Camilla Schalin‐Jäntti,Atte Karppinen,Anders Paetau,Leena Kivipelto,Lauri A. Aaltonen,Auli Karhu	18
4	Comprehensive Evaluation of Protein Coding Mononucleotide Microsatellites in Microsatellite-Unstable Colorectal Cancer 2017 ·Cancer Research ·Johanna Kondelin,Alexandra E. Gylfe,(unknown),Tomas Tanskanen,(unknown),Mervi Aavikko,Kimmo Palin,Heikki Ristolainen,Riku Katainen,Eevi Kaasinen,Minna Taipale,Jussi Taipale,Laura Renkonen‐Sinisalo,Heikki Järvinen,Jan Böhm,Jukka‐Pekka Mecklin,Pia Vahteristo,Sari Tuupanen,Lauri A. Aaltonen,Esa Pitkänen	14
5	Integrated data analysis reveals uterine leiomyoma subtypes with distinct driver pathways and biomarkers 2016 ·Proceedings of the National Academy of Sciences ·Miika Mehine,Eevi Kaasinen,Hanna-Riikka Heinonen,Netta Mäkinen,Kati Kämpjärvi,Nanna Sarvilinna,Mervi Aavikko,Anna Vähärautio,Annukka Pasanen,Ralf Bützow,Oskari Heikinheimo,Jari Sjöberg,Esa Pitkänen,Pia Vahteristo,Lauri A. Aaltonen	157
6	HOXB13 G84E Mutation in Finland: Population-Based Analysis of Prostate, Breast, and Colorectal Cancer Risk 2013 ·Cancer Epidemiology Biomarkers & Prevention ·Virpi H. Laitinen,Tiina Wahlfors,(unknown),Tommi Rantapero,Liisa M. Pelttari,Outi Kilpivaara,(unknown),Anne Kallioniemi,Heli Nevanlinna,Lauri A. Aaltonen,Robert L. Vessella,Anssi Auvinen,Tapio Visakorpi,Teuvo L.J. Tammela,Johanna Schleutker	65
7	Mice Lacking a Myc Enhancer That Includes Human SNP rs6983267 Are Resistant to Intestinal Tumors 2012 ·Science ·Inderpreet Sur,Outi Hallikas,Anna Vähärautio,Jian Yan,Mikko Turunen,Martin Enge,Minna Taipale,Auli Karhu,Lauri A. Aaltonen,Jussi Taipale	149
8	MED12 , the Mediator Complex Subunit 12 Gene, Is Mutated at High Frequency in Uterine Leiomyomasbreakdown → 2011 ·Science ·Netta Mäkinen,Miika Mehine,Jaana Tolvanen,Eevi Kaasinen,Yilong Li,Heli Lehtonen,Massimiliano Gentile,Jian Yan,Martin Enge,Minna Taipale,Mervi Aavikko,Riku Katainen,Elina Virolainen,Tom Böhling,(unknown),Virpi Launonen,Jari Sjöberg,Jussi Taipale,Pia Vahteristo,Lauri A. Aaltonen	470
9	An A13 Repeat within the 3′-Untranslated Region of Epidermal Growth Factor Receptor (EGFR) Is Frequently Mutated in Microsatellite Instability Colon Cancers and Is Associated with Increased EGFR Expression 2009 ·Cancer Research ·Ziqiang Yuan,Joongho Shin,Andrew J. Wilson,Sanjay Goel,Yi‐He Ling,Naseem Ahmed,Higinio Dopeso,Minaxi Jhawer,Shannon Nasser,Cristina Montagna,Kenneth Fordyce,Leonard H. Augenlicht,Lauri A. Aaltonen,Diego Arango,Thomas K. Weber,John M. Mariadason	32
10	Metastasis-Associated Gene Expression Changes Predict Poor Outcomes in Patients with Dukes Stage B and C Colorectal Cancer 2009 ·Clinical Cancer Research ·Robert N. Jorissen,Peter Gibbs,Michael Christie,Saurabh Prakash,Lara Lipton,Jayesh Desai,Rachel Kerr,Lauri A. Aaltonen,Diego Arango,Mogens Kruhøffer,Torben F. Ørntoft,Claus L. Andersen,Mike Gruidl,Vidya Kamath,Steven A. Eschrich,Timothy J. Yeatman,Oliver M. Sieber	343
11	DNA Copy-Number Alterations Underlie Gene Expression Differences between Microsatellite Stable and Unstable Colorectal Cancers 2008 ·Clinical Cancer Research ·Robert N. Jorissen,Lara Lipton,Peter Gibbs,Matthew Chapman,Jayesh Desai,Ian T. Jones,Timothy J. Yeatman,Philip East,Ian Tomlinson,Hein W. Verspaget,Lauri A. Aaltonen,Mogens Kruhøffer,Torben F. Ørntoft,Claus L. Andersen,Oliver M. Sieber	75
12	Functional Diversity of Human Protection of Telomeres 1 Isoforms in Telomere Protection and Cellular Senescence 2007 ·Cancer Research ·Qin Yang,Ran Zhang,Izumi Horikawa,Kaori Fujita,Yalda Afshar,Antti Kokko,Päivi Laiho,Lauri A. Aaltonen,Curtis C. Harris	28
13	EPHB4 and Survival of Colorectal Cancer Patients 2006 ·Cancer Research ·Verónica Dávalos,Higinio Dopeso,Julio Castaño,Andrew J. Wilson,F Vilardell,Jordi Romero‐Giménez,Eloy Espín,Manel Armengol,Gabriel Capellá,John M. Mariadason,Lauri A. Aaltonen,Simó Schwartz,Diego Arango	66
14	Pituitary Adenoma Predisposition Caused by Germline Mutations in the AIP Gene 2006 ·Science ·Outi Vierimaa,Marianthi Georgitsi,Rainer Lehtonen,Pia Vahteristo,Antti Kokko,Anniina Raitila,Karoliina Tuppurainen,Tapani Ebeling,Pasi Salmela,Ralf Paschke,Sadi Gündoğdu,Ernesto De Menis,Markus J. Mäkinen,Virpi Launonen,Auli Karhu,Lauri A. Aaltonen	408
15	Mechanisms of Inactivation of the Receptor Tyrosine Kinase EPHB2 in Colorectal Tumors 2005 ·Cancer Research ·Hafid Alazzouzi,Verónica Dávalos,Antti Kokko,Enric Domingo,Stefan M. Woerner,Andrew J. Wilson,(unknown),Päivi Laiho,Eloy Espín,Manel Armengol,Kohzoh Imai,Hiroyuki Yamamoto,John M. Mariadason,Johannes Gebert,Lauri A. Aaltonen,Simó Schwartz,Diego Arango	75
16	SMAD4 Levels and Response to 5-Fluorouracil in Colorectal Cancer 2005 ·Clinical Cancer Research ·Pia Alhopuro,Hafid Alazzouzi,Heli Sammalkorpi,Verónica Dávalos,Reijo Salovaara,Akseli Hemminki,Heikki Järvinen,Jukka‐Pekka Mecklin,Simó Schwartz,Lauri A. Aaltonen,Diego Arango	74
17	Little evidence for involvement of MLH3 in colorectal cancer predisposition 2003 ·International Journal of Cancer ·(unknown),Päivi Laiho,Reijo Salovaara,Jukka‐Pekka Mecklin,Heikki Järvinen,Pertti Sistonen,Païvi Peltomäki,Rainer Lehtonen,Nina N. Nupponen,Virpi Launonen,Auli Karhu,Lauri A. Aaltonen	39
18	Cancer risk in mutation carriers of DNA‐mismatch‐repair genes 1999 ·International Journal of Cancer ·Markku Aarnio,Risto Sankila,Eero Pukkala,Reijo Salovaara,Lauri A. Aaltonen,Albert de la Chapelle,Païvi Peltomäki,Jukka‐Pekka Mecklin,Heikki Järvinen	74
19	Cancer risk in mutation carriers of DNA-mismatch-repair genesbreakdown → 1999 ·International Journal of Cancer ·Markku Aarnio,Risto Sankila,Eero Pukkala,Reijo Salovaara,Lauri A. Aaltonen,Albert de la Chapelle,(unknown),Jukka‐Pekka Mecklin,(unknown)	889
20	Epidural morphine as postoperative analgesic following cesarean section under epidural analgesia. 1985 ·PubMed ·J Kanto,R Erkkola,Lauri A. Aaltonen,(unknown)	1

About Lauri A. Aaltonen

Lauri A. Aaltonen is a scholar working on Pathology and Forensic Medicine, Cancer Research and Oncology, having authored 284 papers that have together received 22.9k indexed citations. Recurring topics across this work include Genetic factors in colorectal cancer (148 papers), Cancer Genomics and Diagnostics (56 papers) and Colorectal Cancer Treatments and Studies (52 papers). The work is most often cited by research in Pathology and Forensic Medicine (12.3k citations), Cancer Research (6.5k citations) and Oncology (10.0k citations). Lauri A. Aaltonen has collaborated with scholars based in Finland, United States and United Kingdom. Frequent co-authors include Jukka‐Pekka Mecklin, Heikki Järvinen, Albert de la Chapelle, Reijo Salovaara, Païvi Peltomäki, Markku Aarnio, Minna Nyström, Eero Pukkala, Akseli Hemminki and Virpi Launonen. Their work appears in journals such as Science, New England Journal of Medicine and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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