Adrian J. Thrasher

44.2k total citations · 3 hit papers
401 papers, 21.8k citations indexed

About

Adrian J. Thrasher is a scholar working on Molecular Biology, Genetics and Oncology. According to data from OpenAlex, Adrian J. Thrasher has authored 401 papers receiving a total of 21.8k indexed citations (citations by other indexed papers that have themselves been cited), including 216 papers in Molecular Biology, 201 papers in Genetics and 111 papers in Oncology. Recurrent topics in Adrian J. Thrasher's work include Virus-based gene therapy research (172 papers), CAR-T cell therapy research (101 papers) and CRISPR and Genetic Engineering (82 papers). Adrian J. Thrasher is often cited by papers focused on Virus-based gene therapy research (172 papers), CAR-T cell therapy research (101 papers) and CRISPR and Genetic Engineering (82 papers). Adrian J. Thrasher collaborates with scholars based in United Kingdom, United States and Germany. Adrian J. Thrasher's co-authors include Christine Kinnon, Siobhan O. Burns, Michael P. Blundell, Robin R. Ali, Gareth E. Jones, H. Bobby Gaspar, James Bainbridge, Steven J. Howe, David Goldblatt and Alexander J. Smith and has published in prestigious journals such as Nature, New England Journal of Medicine and Proceedings of the National Academy of Sciences.

In The Last Decade

Adrian J. Thrasher

393 papers receiving 21.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis

2008 1.5k citations Adrian J. Thrasher et al. profile →
Sustained Correction of X-Linked Severe Combined Immunodeficiency by ex Vivo Gene Therapy

2002 731 citations Adrian J. Thrasher, Marina Cavazzana et al. profile →
The cytoplasm of living cells behaves as a poroelastic material

2013 493 citations Dale Moulding, Adrian J. Thrasher et al. profile →

Peers

Countries citing papers authored by Adrian J. Thrasher

Since Specialization

Citations

This map shows the geographic impact of Adrian J. Thrasher's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Adrian J. Thrasher with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Adrian J. Thrasher more than expected).

Fields of papers citing papers by Adrian J. Thrasher

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Adrian J. Thrasher. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Adrian J. Thrasher. The network helps show where Adrian J. Thrasher may publish in the future.

Co-authorship network of co-authors of Adrian J. Thrasher

This figure shows the co-authorship network connecting the top 25 collaborators of Adrian J. Thrasher. A scholar is included among the top collaborators of Adrian J. Thrasher based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Adrian J. Thrasher. Adrian J. Thrasher is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Betibeglogene Autotemcel (Beti-cel) Gene Addition Therapy Results in Durable Hemoglobin A (HbA) Production with up to 10 Years of Follow-up in Participants with Transfusion-Dependent β-Thalassemia 2025 ·Transplantation and Cellular Therapy ·Timothy S. Olson, Alexis A. Thompson, Janet L. Kwiatkowski, Jennifer Schneiderman, Isabelle Thuret, Andreas E. Kulozik, Evangelia Yannaki, Marina Cavazzana, Suradej Hongeng, Martin G. Sauer, Adrian J. Thrasher, Ashutosh Lal, John E.J. Rasko, (unknown), Tao Ge, (unknown), (unknown), Mark C. Walters, Franco Locatelli	0
2	Potent and Effective Targeting of AML with ‘Off-the-Shelf’ Engineered CD45-Targeting CAR T-Cells 2024 ·Blood ·(unknown), Aiyin Liao, Naeem Khan, Sylvie Freeman, Thomas E. Whittaker, Adrian J. Thrasher, Martin Pulé, Kerry Chester, Jenny Yeung, (unknown)	2
3	Evaluation of Mobilization, Apheresis, and Conditioning Regimen and Engraftment in Patients Receiving One-Time Gene Therapy with Elivaldogene Autotemcel (Eli-cel) for Cerebral Adrenoleukodystrophy (CALD) 2024 ·Transplantation and Cellular Therapy ·Christine Duncan, Paul J. Orchard, Florian Eichler, Jörn‐Sven Kühl, Satiro De Oliveira, Adrian J. Thrasher, Robert Chiesa, Jean‐Hugues Dalle, Ami J. Shah, Franco Locatelli, Nicholas Smith, Juliana Folloni Fernandes, Hernán Amartino, Caroline A. Lindemans, Jack Zhao, Ajay Singh, (unknown), Vinod K. Prasad, Andrew C. Dietz, David A. Williams	1
4	Critical role of WASp in germinal center tolerance through regulation of B cell apoptosis and diversification 2022 ·Cell Reports ·Marc Descatoire, Rémi Fritzen, Samuel Rotman, (unknown), (unknown), (unknown), Adrian J. Thrasher, Elisabetta Traggiai, Fabio Candotti	6
5	Elivaldogene Autotemcel (eli-cel, Lenti-D) Gene Therapy for the Treatment of Cerebral Adrenoleukodystrophy: Updated Results from the Phase 2/3 ALD-102 Study and First Report on Safety Outcomes from the Phase 3 ALD-104 Study 2021 ·Transplantation and Cellular Therapy ·Paul J. Orchard, Christine Duncan, Florian Eichler, Satiro De Oliveira, Adrian J. Thrasher, Caroline Sevin, Hernán Amartino, Nicholas Smith, Jörn‐Sven Kühl, Daniel Kenney‐Jung, Robert Chiesa, Jean‐Hugues Dalle, Jing Xu, Andrew C. Dietz, Elizabeth McNeil, Patrick Aubourg, David A. Williams	2
6	Safety and Efficacy Outcomes in Pediatric Patients with Transfusion-Dependent β-Thalassemia (TDT) Receiving Betibeglogene Autotemcel (beti-cel; LentiGlobin for β-thalassemia) Gene Therapy in the Phase 3 Hgb-207 (Northstar-2) and Hgb-212 (Northstar-3) Studies 2021 ·Transplantation and Cellular Therapy ·Mark C. Walters, Janet L. Kwiatkowski, John B. Porter, Suradej Hongeng, Evangelia Yannaki, Andreas E. Kulozik, Martin G. Sauer, Adrian J. Thrasher, Isabelle Thuret, Ashutosh Lal, Ruiting Guo, Weijian Liu, Richard A. Colvin, Franco Locatelli, Alexis A. Thompson	1
7	Efficacy and Safety of Betibeglogene Autotemcel (beti-cel; LentiGlobin for β-thalassemia) Gene Therapy in 60 Patients with Transfusion-Dependent β-Thalassemia (TDT) Followed for up to 6 Years Post-Infusion 2021 ·Transplantation and Cellular Therapy ·Suradej Hongeng, Alexis A. Thompson, Janet L. Kwiatkowski, Franco Locatelli, John B. Porter, John E.J. Rasko, Marina Cavazzana, Martin G. Sauer, Adrian J. Thrasher, Isabelle Thuret, Ashutosh Lal, Andreas E. Kulozik, Evangelia Yannaki, Manfred Schmidt, (unknown), Ruiting Guo, Weijian Liu, Richard A. Colvin, Mark C. Walters	1
8	Novel human liver-tropic AAV variants define transferable domains that markedly enhance the human tropism of AAV7 and AAV8 2021 ·Molecular Therapy — Methods & Clinical Development ·Marti Cabanes‐Creus, (unknown), Erhua Zhu, (unknown), Sophia H.Y. Liao, Matthieu Drouyer, Anais K. Amaya, Suzanne Scott, (unknown), Adrian Westhaus, Matthias Hebben, Natalie A. Twine, Adrian J. Thrasher, Ian E. Alexander, Leszek Lisowski	24
9	Restoring the natural tropism of AAV2 vectors for human liver 2020 ·Science Translational Medicine ·Marti Cabanes‐Creus, Claus V. Hallwirth, Adrian Westhaus, Boaz H. Ng, Sophia H.Y. Liao, Erhua Zhu, (unknown), (unknown), Matthieu Drouyer, Suzanne Scott, Grant J. Logan, Giorgia Santilli, Antonette Bennett, Samantha L. Ginn, Geoffrey W. McCaughan, Adrian J. Thrasher, Mavis Agbandje‐McKenna, Ian E. Alexander, Leszek Lisowski	33
10	Correction of both immunodeficiency and hypoparathyroidism by thymus transplantation in complete DiGeorge syndrome 2019 ·American Journal of Transplantation ·Alexandra Y. Kreins, (unknown), William Mifsud, (unknown), Neil J. Sebire, Dyanne Rampling, Austen Worth, (unknown), Catharina Schuetz, Ansgar Schulz, Manfred Hoenig, Adrian J. Thrasher, E. Graham Davies	9
11	Autoinflammatory periodic fever, immunodeficiency, and thrombocytopenia (PFIT) caused by mutation in actin-regulatory gene WDR1 2016 ·The Journal of Experimental Medicine ·Ariane Standing, Dessislava Malinova, Ying Hong, Julien Record, Dale Moulding, Michael P. Blundell, Karolin Nowak, Hannah E. Jones, Ebun Omoyinmi, Kimberly Gilmour, Alan Medlar, Horia Stanescu, Robert Kleta, Glenn Anderson, Sira Nanthapisal, Sónia Gomes, Nigel Klein, Despina Eleftheriou, Adrian J. Thrasher, Paul Brogan	105
12	Deletion of Wiskott–Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells 2016 ·Nature Communications ·Marisa A. P. Baptista, Márton Keszei, Mariana M.S. Oliveira, Karen K. S. Sunahara, John Andersson, Carin Dahlberg, Austen Worth, Agne Liedén, I-Chun Kuo, Robert P. A. Wallin, Scott B. Snapper, Liv Eidsmo, Annika Scheynius, Mikael C. I. Karlsson, Gerben Bouma, Siobhan O. Burns, Mattias N.E. Forsell, Adrian J. Thrasher, Susanne Nylén, Lisa S. Westerberg	27
13	FOXP3+ Tregs require WASP to restrain Th2-mediated food allergy 2016 ·Journal of Clinical Investigation ·Willem S. Lexmond, Jeremy A. Goettel, Jonathan J. Lyons, Justin Jacobse, Marion M. Deken, Monica G. Lawrence, Thomas DiMaggio, Daniel Kotlarz, Elizabeth Garabedian, Paul Sackstein, (unknown), Nina Jones, Kelly D. Stone, Fabio Candotti, Edmond H.H.M. Rings, Adrian J. Thrasher, Joshua D. Milner, Scott B. Snapper, Edda Fiebiger	46
14	N-WASP is required for B-cell–mediated autoimmunity in Wiskott-Aldrich syndrome 2015 ·Blood ·Stefano Volpi, (unknown), (unknown), Masayuki Mizui, Carin Dahlberg, Mike Recher, Kelly Capuder, Eva Csizmadia, (unknown), Divij Mathew, George C. Tsokos, Scott B. Snapper, Lisa S. Westerberg, Adrian J. Thrasher, Fabio Candotti, Luigi D. Notarangelo	21
15	Trisomy 21 Mid-Trimester Amniotic Fluid Induced Pluripotent Stem Cells Maintain Genetic Signatures During Reprogramming: Implications for Disease Modeling and Cryobanking 2014 ·Cellular Reprogramming ·Caterina Pipino, Sayandip Mukherjee, Anna L. David, Michael P. Blundell, Steven W. Shaw, (unknown), Panicos Shangaris, Jonathan J. Waters, (unknown), Marina Cavazzana, Gustavo Mostoslavsky, Assunta Pandolfi, Agostino Pierro, Pascale V. Guillot, Adrian J. Thrasher, Paolo De Coppi	10
16	Phase I Study Protocol for Ex Vivo Lentiviral Gene Therapy for the Inherited Skin Disease, Netherton Syndrome 2013 ·PubMed ·Wei‐Li Di, Jemima E. Mellerio, (unknown), John Harper, Alya Abdul‐Wahab, (unknown), Lucas Chan, Magdalena Martinez-Queipo, Havinder Hara, Anne‐Marie McNicol, Farzin Farzaneh, John A. McGrath, Adrian J. Thrasher, Waseem Qasim	27
17	Phosphorylation of WASp is a key regulator of activity and stability in vivo 2009 ·Proceedings of the National Academy of Sciences ·Michael P. Blundell, Gerben Bouma, (unknown), Austen Worth, Yolanda Calle, (unknown), Lisa S. Westerberg, Dale Moulding, (unknown), Christine Kinnon, Giles O. Cory, Gareth E. Jones, Scott B. Snapper, Siobhan O. Burns, Adrian J. Thrasher	48
18	Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice (vol 12, pg 763, 2005) 2006 ·UCL Discovery (University College London) ·Michael Themis, Simon N. Waddington, Manfred Schmidt, Christof von Kalle, (unknown), Faisal A. Al-Allaf, (unknown), Megha Nivsarkar, (unknown), (unknown), Suzanne M. K. Buckley, Niraja Dighe, (unknown), Ajay Mistry, Brian Bigger, Ahad A. Rahim, (unknown), Didier Trono, Adrian J. Thrasher, Charles Coutelle	0
19	Update on treatment of human SCID-X1 by somatic gene therapy using a pseudotyped gammaretroviral vector 2004 ·UCL Discovery (University College London) ·(unknown), (unknown), (unknown), Kimberly Gilmour, Joanna Sinclair, (unknown), (unknown), Gareth E. Davies, Christine Kinnon, Adrian J. Thrasher	6
20	Engraftment in NOD/SCID mice of placental/umbilical cord blood stem cells expanded in a stroma- and serum-free medium: A system suitable for clinical application. 1999 ·UCL Discovery (University College London) ·Lorenza Lazzari, Adrian J. Thrasher, Simona Lucchi, (unknown), Laura Porretti, Lucilla Lecchi, (unknown), (unknown)	1

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