Ian E. Alexander

14.0k total citations · 2 hit papers
178 papers, 7.6k citations indexed

About

Ian E. Alexander is a scholar working on Genetics, Molecular Biology and Immunology. According to data from OpenAlex, Ian E. Alexander has authored 178 papers receiving a total of 7.6k indexed citations (citations by other indexed papers that have themselves been cited), including 111 papers in Genetics, 107 papers in Molecular Biology and 23 papers in Immunology. Recurrent topics in Ian E. Alexander's work include Virus-based gene therapy research (97 papers), CRISPR and Genetic Engineering (50 papers) and RNA Interference and Gene Delivery (39 papers). Ian E. Alexander is often cited by papers focused on Virus-based gene therapy research (97 papers), CRISPR and Genetic Engineering (50 papers) and RNA Interference and Gene Delivery (39 papers). Ian E. Alexander collaborates with scholars based in Australia, United Kingdom and United States. Ian E. Alexander's co-authors include Samantha L. Ginn, A. Dusty Miller, David W. Russell, Michael Edelstein, Sharon C. Cunningham, Mohammad Abedi, Jo Wixon, Allison Dane, Anais K. Amaya and Leszek Lisowski and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

In The Last Decade

Ian E. Alexander

171 papers receiving 7.4k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Gene therapy clinical trials worldwide to 2012 – an update

2013 916 citations Samantha L. Ginn, Ian E. Alexander et al. profile →
Gene therapy clinical trials worldwide to 2017: An update

2018 586 citations Samantha L. Ginn, Anais K. Amaya et al. profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author						Papers	Cites
Ian E. Alexander	5.0k	4.2k	1.0k	813	784	178	7.6k
Stefan Kochanek	5.7k 1.1×	5.1k 1.2×	1.5k 1.5×	612 0.8×	987 1.3×	150	7.9k
Richard J. Gregory	4.9k 1.0×	2.2k 0.5×	1.1k 1.1×	640 0.8×	386 0.5×	70	10.3k
Lawrence W. Stanton	6.9k 1.4×	1.1k 0.3×	680 0.7×	604 0.7×	638 0.8×	124	10.4k
Mamoru Hasegawa	5.6k 1.1×	1.8k 0.4×	765 0.8×	691 0.8×	611 0.8×	197	8.5k
Andréa Pavirani	4.1k 0.8×	3.6k 0.9×	1.1k 1.1×	633 0.8×	796 1.0×	115	7.6k
Antonia Follenzi	4.6k 0.9×	2.0k 0.5×	1.0k 1.0×	1.6k 1.9×	346 0.4×	156	8.9k
Arun Srivastava	6.6k 1.3×	6.9k 1.7×	1.4k 1.4×	1.1k 1.3×	1.8k 2.3×	219	9.6k
Imre Kovesdi	6.6k 1.3×	5.8k 1.4×	3.0k 2.9×	840 1.0×	1.2k 1.5×	141	10.4k
Chengwen Li	3.7k 0.7×	3.4k 0.8×	886 0.9×	511 0.6×	399 0.5×	111	5.2k
Tal Kafri	5.6k 1.1×	3.5k 0.8×	1.0k 1.0×	539 0.7×	444 0.6×	76	7.8k

Countries citing papers authored by Ian E. Alexander

Since Specialization

Citations

This map shows the geographic impact of Ian E. Alexander's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ian E. Alexander with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ian E. Alexander more than expected).

Fields of papers citing papers by Ian E. Alexander

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ian E. Alexander. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ian E. Alexander. The network helps show where Ian E. Alexander may publish in the future.

Co-authorship network of co-authors of Ian E. Alexander

This figure shows the co-authorship network connecting the top 25 collaborators of Ian E. Alexander. A scholar is included among the top collaborators of Ian E. Alexander based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ian E. Alexander. Ian E. Alexander is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Alikhan, Maliha A., Lu Lu, Kate E. Lawlor, et al.. (2025). Gene therapy enhances deoxyribonuclease I treatment in antimyeloperoxidase glomerulonephritis. JCI Insight. 10(15).

Mietzsch, Mario, Ang Huang, Nicholas Smith, et al.. (2025). Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts. Nature Communications. 16(1). 3731–3731. 5 indexed citations

Zhu, Erhua, et al.. (2025). Targeted editing of the 21-hydroxylase locus confers durable therapeutic effect in a murine model of congenital adrenal hyperplasia. Molecular Therapy. 34(2). 1138–1151.

Ng, Roy Chun-Laam, Min Jian, Jason Shing-Cheong Kwan, et al.. (2024). Liver-specific adiponectin gene therapy suppresses microglial NLRP3-inflammasome activation for treating Alzheimer’s disease. Journal of Neuroinflammation. 21(1). 77–77. 16 indexed citations

Ginn, Samantha L., et al.. (2024). Genome editing in the adrenal gland: a novel strategy for treating congenital adrenal hyperplasia. SHILAP Revista de lepidopterología. 1(3). 1 indexed citations

Zhu, Erhua, et al.. (2024). AAV-delivered hepato-adrenal cooperativity in steroidogenesis: Implications for gene therapy for congenital adrenal hyperplasia. Molecular Therapy — Methods & Clinical Development. 32(2). 101232–101232. 5 indexed citations

Torpy, David J., et al.. (2023). Future Directions for Adrenal Insufficiency: Cellular Transplantation and Genetic Therapies. The Journal of Clinical Endocrinology & Metabolism. 108(6). 1273–1289. 11 indexed citations

Alexander, Ian E., et al.. (2023). Gene therapy for urea cycle defects: An update from historical perspectives to future prospects. Journal of Inherited Metabolic Disease. 47(1). 50–62. 13 indexed citations

Logan, Grant J., Mario Mietzsch, Arlene D’Silva, et al.. (2023). Structural and functional characterization of capsid binding by anti-AAV9 monoclonal antibodies from infants after SMA gene therapy. Molecular Therapy. 31(7). 1979–1993. 19 indexed citations

10.

Rao, Renuka, Grant J. Logan, Cindy Kok, et al.. (2022). Performance of Cardiotropic rAAV Vectors Is Dependent on Production Method. Viruses. 14(8). 1623–1623. 2 indexed citations

11.

Malik, Talat H., Daniel P. Gitterman, Deborah Lavin, et al.. (2021). Gain-of-function factor H–related 5 protein impairs glomerular complement regulation resulting in kidney damage. Proceedings of the National Academy of Sciences. 118(13). 17 indexed citations

12.

Cabanes‐Creus, Marti, Erhua Zhu, Sophia H.Y. Liao, et al.. (2021). Novel human liver-tropic AAV variants define transferable domains that markedly enhance the human tropism of AAV7 and AAV8. Molecular Therapy — Methods & Clinical Development. 24. 88–101. 24 indexed citations

13.

Smyth, Christine M., Helen Doyle, Talat H. Malik, et al.. (2021). Adeno-Associated Virus Vector Gene Delivery Elevates Factor I Levels and Downregulates the Complement Alternative Pathway In Vivo. Human Gene Therapy. 32(21-22). 1370–1381. 7 indexed citations

14.

Baruteau, Julien, Sharon C. Cunningham, Berna Şeker Yılmaz, et al.. (2021). Safety and efficacy of an engineered hepatotropic AAV gene therapy for ornithine transcarbamylase deficiency in cynomolgus monkeys. Molecular Therapy — Methods & Clinical Development. 23. 135–146. 23 indexed citations

15.

Logan, Grant J., Sharon C. Cunningham, Najah T. Nassif, et al.. (2020). Use of a Hybrid Adeno-Associated Viral Vector Transposon System to Deliver the Insulin Gene to Diabetic NOD Mice. Cells. 9(10). 2227–2227. 9 indexed citations

16.

Riley, Lisa G., Mark J. Cowley, Velimir Gayevskiy, et al.. (2020). The diagnostic utility of genome sequencing in a pediatric cohort with suspected mitochondrial disease. Genetics in Medicine. 22(7). 1254–1261. 45 indexed citations

17.

Cabanes‐Creus, Marti, Claus V. Hallwirth, Adrian Westhaus, et al.. (2020). Restoring the natural tropism of AAV2 vectors for human liver. Science Translational Medicine. 12(560). 33 indexed citations

18.

Chen, Xiaochen, Jin Ma, Tony Kwan, et al.. (2018). Blockade of HMGB1 Attenuates Diabetic Nephropathy in Mice. Scientific Reports. 8(1). 8319–8319. 52 indexed citations

19.

Wang, Jiang-Hui, Veluchamy A. Barathi, Zheng He, et al.. (2018). AAV-mediated gene delivery of the calreticulin anti-angiogenic domain inhibits ocular neovascularization. Angiogenesis. 21(1). 95–109. 21 indexed citations

20.

Baruteau, Julien, Simon N. Waddington, Ian E. Alexander, & Paul Gissen. (2017). Gene therapy for monogenic liver diseases: clinical successes, current challenges and future prospects. Journal of Inherited Metabolic Disease. 40(4). 497–517. 77 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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