Achim Schlapbach

1.6k citations

29 papers · 1.1k indexed · h-index 20

Impact in

Organic Chemistry top 5%
- Sulfur-Based Synthesis Techniques
- Asymmetric Synthesis and Catalysis
- Synthetic Organic Chemistry Methods
- Chemical Synthesis and Reactions
- Catalytic C–H Functionalization Methods
- Synthesis and biological activity
Cancer Research
- NF-κB Signaling Pathways

Papers in

Organic Chemistry 14
- Synthesis and biological activity 5
- Organoboron and organosilicon chemistry 4
- Asymmetric Synthesis and Catalysis 4
- Chemical Synthesis and Reactions 4
Cancer Research 6
- Beetle Biology and Toxicology Studies 3

Co-authors: Ulrich Schopfer Reinhard W. Hoffmann Láśzló Révész Roland Feifel Ian Paterson Christine Huppertz G Niel Richard Heng
Journals: Bioorganic & Medicinal Chemistry Letters (10 papers)Tetrahedron (3 papers)ACS Medicinal Chemistry Letters (1 paper)Tetrahedron Letters (1 paper)Future Medicinal Chemistry (1 paper)
Partner nations: Switzerland Germany United States

In The Last Decade

Achim Schlapbach

29 papers receiving 1.1k citations

Peers

Countries citing papers authored by Achim Schlapbach

Since Specialization

Citations

This map shows the geographic impact of Achim Schlapbach's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Achim Schlapbach with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Achim Schlapbach more than expected).

Fields of papers citing papers by Achim Schlapbach

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Achim Schlapbach. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Achim Schlapbach. The network helps show where Achim Schlapbach may publish in the future.

Co-authors

The 25 scholars most cited alongside Achim Schlapbach, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Achim Schlapbach Line = papers co-authored together Achim Schlapbach links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Pharmacological inhibition of IKKβ dampens NLRP3 inflammasome activation after priming in the human myeloid cell line THP-1 Biochemical and Biophysical Research Communications ·喜平中山, Ma Angeles Barrio Guirad, Kristopher E. Van Zandt, 吴维伟, Diane Heiser, P. Erbel, Achim Schlapbach, Jörg Eder, Ursula Bodendorf, Andreas Boettcher, Christopher J. Farady, Frédéric Bornancin	2021	12
2	An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient Nature Chemical Biology ·Jean Quancard, Théo Klein, Shan‐Yu Fung, Martin Renatus, Nicola Hughes, Laura Israël, John J. Priatel, Sohyeong Kang, Michael A. Blank, Rosa Viner, Jutta Blank, Achim Schlapbach, P. Erbel, Jayachandran N. Kizhakkedathu, Frédéric Villard, René Hersperger, Stuart E. Turvey, M.L. Jansen, Frédéric Bornancin, Christopher M. Overall	2019	41
3	N-aryl-piperidine-4-carboxamides as a novel class of potent inhibitors of MALT1 proteolytic activity Bioorganic & Medicinal Chemistry Letters ·Achim Schlapbach, Láśzló Révész, Carole Pissot‐Soldermann, Thomas Zöller, Catherine H. Régnier, Frédéric Bornancin, Thomas Radimerski, Jutta Blank, Ansgar Schuffenhauer, Martin Renatus, P. Erbel, Samu Melkko, Richard Heng, Oliver Simić, Carol Moor, Markus Wartmann, Jean Quancard	2018	18
4	In vitro and in vivo characterization of a novel, highly potent p53-MDM2 inhibitor Bioorganic & Medicinal Chemistry Letters ·Andrea Vaupel, Philipp Holzer, Stéphane Ferretti, Vito Guagnano, Joerg Kallen, Robert Mah, Keiichi Masuya, Stephan Ruetz, Caroline Rynn, Achim Schlapbach, Therese‐Marie Stachyra, Stefan Stutz, Milen Todorov, Sébastien Jeay, Pascal Furet	2018	16
5	Discovery of a novel class of highly potent inhibitors of the p53–MDM2 interaction by structure-based design starting from a conformational argument Bioorganic & Medicinal Chemistry Letters ·Pascal Furet, Keiichi Masuya, Joerg Kallen, Therese‐Marie Stachyra, Stephan Ruetz, Vito Guagnano, Philipp Holzer, Robert Mah, Stefan Stutz, Andrea Vaupel, Patrick Chêne, Sébastien Jeay, Achim Schlapbach	2016	60
6	In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inhibitors. Part I Bioorganic & Medicinal Chemistry Letters ·Láśzló Révész, Achim Schlapbach, Reiner Aichholz, Roland Feifel, Stuart Hawtin, Richard Heng, Peter Hiestand, Wolfgang Jahnke, Guido Koch, M. Kroemer, Henrik Möbitz, Clemens Scheufler, Juraj Velcicky, Christine Huppertz	2010	23
7	In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inhibitors. Part II Bioorganic & Medicinal Chemistry Letters ·Láśzló Révész, Achim Schlapbach, Reiner Aichholz, Janet Dawson, Roland Feifel, Stuart Hawtin, Amanda Littlewood‐Evans, Guido Koch, M. Kroemer, Henrik Möbitz, Clemens Scheufler, Juraj Velcicky, Christine Huppertz	2010	27
8	Novel 3-aminopyrazole inhibitors of MK-2 discovered by scaffold hopping strategy Bioorganic & Medicinal Chemistry Letters ·Juraj Velcicky, Roland Feifel, Stuart Hawtin, Richard Heng, Christine Huppertz, Guido Koch, M. Kroemer, Henrik Moebitz, Láśzló Révész, Clemens Scheufler, Achim Schlapbach	2009	35
9	Pyrrolo-pyrimidones: A novel class of MK2 inhibitors with potent cellular activity Bioorganic & Medicinal Chemistry Letters ·Achim Schlapbach, Roland Feifel, Stuart Hawtin, Richard Heng, Guido Koch, Henrik Moebitz, Láśzló Révész, Clemens Scheufler, Juraj Velcicky, Rudolf Waelchli, Christine Huppertz	2008	35
10	The Role of Interstitial Macrophages in Nephropathy of Type 2 Diabetic db/db Mice American Journal Of Pathology ·Volha Ninichuk, Alexander G. Khandoga, Stephan Segerer, Pius Loetscher, Achim Schlapbach, Láśzló Révész, Roland Feifel, Andrej Khandoga, Fritz Krombach, Peter J. Nelson, Detlef Schlöndorff, Hans‐Joachim Anders	2007	81
11	Identification of Human Kinases Involved in Hepatitis C Virus Replication by Small Interference RNA Library Screening Journal of Biological Chemistry ·Ľubica Supeková, František Supek, Jong‐Kook Lee, Shawn Chen, Nathanael S. Gray, John Paul Pezacki, Achim Schlapbach, Peter G. Schultz	2007	84
12	Bridged Piperazines and Piperidines as CCR1 Antagonists with Oral Activity in Models of Arthritis and Multiple Sclerosis Letters in Drug Design & Discovery ·Láśzló Révész, Birgit Bollbuck, Thomas Buhl, Janet Dawson, Roland Feifel, Richard Heng, Peter Hiestand, Helmut Sparrer, Achim Schlapbach, Rudolf Waelchli, Pius Loetscher	2006	7
13	Design and preparation of 2-benzamido-pyrimidines as inhibitors of IKK Bioorganic & Medicinal Chemistry Letters ·Rudolf Waelchli, Birgit Bollbuck, Christian Bruns, Thomas Buhl, Jörg Eder, Roland Feifel, René Hersperger, Philipp Janser, Láśzló Révész, Hans‐Günter Zerwes, Achim Schlapbach	2005	121
14	Novel CCR1 antagonists with oral activity in the mouse collagen induced arthritis Bioorganic & Medicinal Chemistry Letters ·Láśzló Révész, Birgit Bollbuck, Thomas Buhl, M.L. Jansen, Ronald E. Esser, Roland Feifel, Richard Heng, Peter Hiestand, Le Fang, Pius Loetscher, Helmut Sparrer, Achim Schlapbach, Rudolf Waelchli	2005	24
15	A novel Pd-catalyzed cyclization reaction of ureas for the synthesis of dihydroquinazolinone p38 kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·Achim Schlapbach, Richard Heng, Franco Di Padova	2003	15
16	A general palladium-catalysed synthesis of aromatic and heteroaromatic thioethers Tetrahedron ·Ulrich Schopfer, Achim Schlapbach	2001	171
17	Synthesis of the trioxadecalin-part of mycalamide B Tetrahedron Letters ·Reinhard W. Hoffmann, Achim Schlapbach	1993	28
18	Stereoselective synthesis of alcohols, XLI. Chirality transfer to generate quaternary stereogenic centers by an allylboration reaction Liebigs Annalen der Chemie ·Reinhard W. Hoffmann, Achim Schlapbach	1991	19
19	Stereoselective synthesis of alcohols, XXXVI. Stereoselective generation of homoallyl alcohols having quaternary stereogenic centers Liebigs Annalen der Chemie ·Reinhard W. Hoffmann, Achim Schlapbach	1990	17
20	Stereocontrol in allylboration reactions Pure and Applied Chemistry ·Reinhard W. Hoffmann, G Niel, Achim Schlapbach	1990	62

About Achim Schlapbach

Achim Schlapbach is a scholar working on Organic Chemistry, Cancer Research, Oncology, Molecular Biology and Immunology, having authored 29 papers that have together received 1.1k indexed citations. Recurring topics across this work include Melanoma and MAPK Pathways (7 papers), Synthesis and biological activity (5 papers), Organoboron and organosilicon chemistry (4 papers), Asymmetric Synthesis and Catalysis (4 papers), Chemical Synthesis and Reactions (4 papers), Beetle Biology and Toxicology Studies (3 papers), Chemical Synthesis and Analysis (3 papers) and Protein Kinase Regulation and GTPase Signaling (3 papers). The work is most often cited by research in Organic Chemistry (523 citations), Cancer Research (148 citations), Toxicology (33 citations), Oncology (206 citations) and Molecular Biology (467 citations). Achim Schlapbach has collaborated with scholars based in Switzerland, Germany and United States. Frequent co-authors include Ulrich Schopfer, Reinhard W. Hoffmann, Láśzló Révész, Roland Feifel, Ian Paterson, Christine Huppertz, G Niel, Richard Heng, Rudolf Waelchli and René Hersperger. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Tetrahedron, ACS Medicinal Chemistry Letters, Tetrahedron Letters and Future Medicinal Chemistry.

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