Théo Klein

2.9k total citations · 1 hit paper
48 papers, 2.2k citations indexed

About

Théo Klein is a scholar working on Cancer Research, Molecular Biology and Oncology. According to data from OpenAlex, Théo Klein has authored 48 papers receiving a total of 2.2k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Cancer Research, 16 papers in Molecular Biology and 14 papers in Oncology. Recurrent topics in Théo Klein's work include Peptidase Inhibition and Analysis (12 papers), Protease and Inhibitor Mechanisms (10 papers) and Chemical Synthesis and Analysis (4 papers). Théo Klein is often cited by papers focused on Peptidase Inhibition and Analysis (12 papers), Protease and Inhibitor Mechanisms (10 papers) and Chemical Synthesis and Analysis (4 papers). Théo Klein collaborates with scholars based in Netherlands, Canada and United States. Théo Klein's co-authors include Rainer Bischoff, Christopher M. Overall, Antoine Dufour, Nestor Solis, Ulrich Eckhard, Peter A. G. Cormack, Kees Ensing, Carlo Crescenzi, Sami Bayoudh and Gunnar Flik and has published in prestigious journals such as Chemical Reviews, Nature Communications and Analytical Chemistry.

In The Last Decade

Théo Klein

45 papers receiving 2.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Physiology and pathophysiology of matrix metalloproteases

2010 668 citations Théo Klein, Rainer Bischoff Amino Acids profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Théo Klein Netherlands	21	886	632	515	310	201	48	2.2k
Carlos Fernández-Patrón Canada	30	966 1.1×	672 1.1×	394 0.8×	236 0.8×	174 0.9×	63	2.5k
Fang Peng China	34	2.0k 2.3×	688 1.1×	556 1.1×	281 0.9×	203 1.0×	183	3.6k
Paula Meleady Ireland	37	2.8k 3.2×	634 1.0×	457 0.9×	283 0.9×	382 1.9×	166	3.9k
Ge Zhou United States	27	1.1k 1.3×	322 0.5×	640 1.2×	179 0.6×	66 0.3×	51	2.7k
Dominique de Seny Belgium	25	938 1.1×	300 0.5×	207 0.4×	208 0.7×	187 0.9×	56	2.2k
Onn Haji Hashim Malaysia	26	933 1.1×	230 0.4×	220 0.4×	254 0.8×	235 1.2×	114	2.0k
Michael Zhuo Wang United States	20	2.4k 2.7×	1.1k 1.7×	235 0.5×	302 1.0×	65 0.3×	49	3.5k
Jae Wha Kim South Korea	30	1.8k 2.1×	415 0.7×	664 1.3×	548 1.8×	32 0.2×	114	2.9k
H Baumann United States	16	696 0.8×	226 0.4×	751 1.5×	933 3.0×	45 0.2×	27	2.6k
Liwei Dong China	35	1.6k 1.8×	686 1.1×	440 0.9×	546 1.8×	71 0.4×	102	3.2k

Countries citing papers authored by Théo Klein

Since Specialization

Citations

This map shows the geographic impact of Théo Klein's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Théo Klein with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Théo Klein more than expected).

Fields of papers citing papers by Théo Klein

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Théo Klein. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Théo Klein. The network helps show where Théo Klein may publish in the future.

Co-authorship network of co-authors of Théo Klein

This figure shows the co-authorship network connecting the top 25 collaborators of Théo Klein. A scholar is included among the top collaborators of Théo Klein based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Théo Klein. Théo Klein is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Klein, Théo, Ly Tu, Laurie W. Geenen, et al.. (2022). Kynurenine metabolites predict survival in pulmonary arterial hypertension: A role for IL-6/IL-6Rα. Scientific Reports. 12(1). 12326–12326. 10 indexed citations

Velsen, Evert F S van, Marcel E. Meima, Théo Klein, et al.. (2021). Change in Thyroid Hormone Metabolite Concentrations Across Different Thyroid States. Thyroid. 32(2). 119–127. 9 indexed citations

Fung, Shan‐Yu, Henry Y. Lu, Mehul Sharma, et al.. (2021). MALT1-Dependent Cleavage of HOIL1 Modulates Canonical NF-κB Signaling and Inflammatory Responsiveness. Frontiers in Immunology. 12. 749794–749794. 7 indexed citations

Broekhuizen, Michelle, Théo Klein, Yolanda B. de Rijke, et al.. (2020). l -Tryptophan–Induced Vasodilation Is Enhanced in Preeclampsia. Hypertension. 76(1). 184–194. 36 indexed citations

Heijs, Bram, Théo Klein, Peter C. Burgers, et al.. (2020). Lipid signature of advanced human carotid atherosclerosis assessed by mass spectrometry imaging. Journal of Lipid Research. 62. 100020–100020. 38 indexed citations

Klein, Théo, Laurie W. Geenen, Ly Tu, et al.. (2020). Lower Plasma Melatonin Levels Predict Worse Long-Term Survival in Pulmonary Arterial Hypertension. Journal of Clinical Medicine. 9(5). 1248–1248. 9 indexed citations

Tam, Vivian, Peikai Chen, Anita Yee, et al.. (2020). DIPPER, a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics. eLife. 9. 49 indexed citations

Klein, Théo, Ly Tu, Laurie W. Geenen, et al.. (2020). Different tryptophan-kynurenine metabolism profiles in human pulmonary arterial hypertension and animal models of pulmonary hypertension. European Heart Journal. 41(Supplement_2). 2 indexed citations

Quancard, Jean, Théo Klein, Shan‐Yu Fung, et al.. (2019). An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient. Nature Chemical Biology. 15(3). 304–313. 41 indexed citations

10.

Dufour, Antoine, Caroline L. Bellac, Ulrich Eckhard, et al.. (2018). C-terminal truncation of IFN-γ inhibits proinflammatory macrophage responses and is deficient in autoimmune disease. Nature Communications. 9(1). 2416–2416. 68 indexed citations

11.

Eckhard, Ulrich, Pitter F. Huesgen, Oliver Schilling, et al.. (2016). Active site specificity profiling datasets of matrix metalloproteinases (MMPs) 1, 2, 3, 7, 8, 9, 12, 13 and 14. Data in Brief. 7. 299–310. 24 indexed citations

12.

Eckhard, Ulrich, Pitter F. Huesgen, Oliver Schilling, et al.. (2015). Active site specificity profiling of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic peptide cleavage analyses. Matrix Biology. 49. 37–60. 160 indexed citations

13.

Klein, Théo, Shan‐Yu Fung, Florian Renner, et al.. (2015). The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling. Nature Communications. 6(1). 8777–8777. 122 indexed citations

14.

Pera, Tonio, Annet B. Zuidhof, Marieke Smit, et al.. (2014). Arginase Inhibition Prevents Inflammation and Remodeling in a Guinea Pig Model of Chronic Obstructive Pulmonary Disease. Journal of Pharmacology and Experimental Therapeutics. 349(2). 229–238. 58 indexed citations

15.

Klein, Théo & Rainer Bischoff. (2010). Physiology and pathophysiology of matrix metalloproteases. Amino Acids. 41(2). 271–290. 668 indexed citations breakdown →

16.

Klein, Théo & Rainer Bischoff. (2010). Active Metalloproteases of the A Disintegrin And Metalloprotease (ADAM) Family: Biological Function and Structure. Journal of Proteome Research. 10(1). 17–33. 138 indexed citations

17.

Geurink, Paul P., Théo Klein, Michiel A. Leeuwenburgh, et al.. (2008). A peptide hydroxamate library for enrichment of metalloproteinases: towards an affinity-based metalloproteinase profiling protocol. Organic & Biomolecular Chemistry. 6(7). 1244–1244. 13 indexed citations

18.

Klein, Théo. (1994). Une manière d'être juif. Le Débat. n° 82(5). 117–128. 1 indexed citations

19.

Klein, Théo, Gerhard Jung, P. Dufour, et al.. (1993). Cancer du sein après maladie de Hodgkin. Analyse de 6 observations.. La Presse Médicale. 22(38). 1928–1929.

20.

Chauvergne, J, et al.. (1978). [Chemotherapy of malignant melanoma. Results of a controlled clinical trial comparing vincristine + dacarbazin (DTIC) with and without duborimycin (author's transl)].. PubMed. 65(2). 107–9. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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