Stephan Ruetz

4.7k total citations · 2 hit papers
36 papers, 3.5k citations indexed

About

Stephan Ruetz is a scholar working on Molecular Biology, Oncology and Cell Biology. According to data from OpenAlex, Stephan Ruetz has authored 36 papers receiving a total of 3.5k indexed citations (citations by other indexed papers that have themselves been cited), including 25 papers in Molecular Biology, 23 papers in Oncology and 9 papers in Cell Biology. Recurrent topics in Stephan Ruetz's work include Drug Transport and Resistance Mechanisms (12 papers), Cancer-related Molecular Pathways (9 papers) and Lipid Membrane Structure and Behavior (6 papers). Stephan Ruetz is often cited by papers focused on Drug Transport and Resistance Mechanisms (12 papers), Cancer-related Molecular Pathways (9 papers) and Lipid Membrane Structure and Behavior (6 papers). Stephan Ruetz collaborates with scholars based in Switzerland, Canada and United States. Stephan Ruetz's co-authors include Piet Gros, Jeanette M. Wood, Jonathan R. Green, Jean Michel Foidart, Laetitia Devy, Vincent Castronovo, Karine Bonjean, Akeila Bellahcène, Philippe Gros and Pascal Furet and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Stephan Ruetz

36 papers receiving 3.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Novel Antiangiogenic Effects of the Bisphosphonate Compound Zoledronic Acid

2002 656 citations Stephan Ruetz et al. profile →
Phosphatidylcholine translocase: A physiological role for the mdr2 gene

1994 509 citations Stephan Ruetz Cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Stephan Ruetz Switzerland	23	2.0k	1.7k	416	368	340	36	3.5k
Kenjiro Sawada Japan	40	1.3k 0.7×	2.7k 1.6×	310 0.7×	52 0.1×	409 1.2×	137	5.0k
Gert Rijksen Netherlands	32	1.2k 0.6×	2.7k 1.6×	312 0.8×	24 0.1×	226 0.7×	151	4.2k
Seiji Mabuchi Japan	42	1.6k 0.8×	2.4k 1.4×	732 1.8×	25 0.1×	509 1.5×	192	5.7k
Gerrit Jan Schuurhuis Netherlands	38	1.4k 0.7×	2.0k 1.2×	209 0.5×	36 0.1×	207 0.6×	114	4.7k
Hitoshi Kiyoi Japan	46	2.1k 1.0×	4.4k 2.5×	88 0.2×	55 0.1×	252 0.7×	277	9.0k
Jacques Jolivet Canada	29	1.0k 0.5×	1.7k 1.0×	127 0.3×	30 0.1×	411 1.2×	91	3.9k
Raymond Taetle United States	38	1.2k 0.6×	2.2k 1.3×	183 0.4×	22 0.1×	267 0.8×	129	4.4k
Bruno Quesnel France	47	2.6k 1.3×	3.5k 2.0×	148 0.4×	59 0.2×	504 1.5×	202	8.1k
Soheil Meshinchi United States	49	1.4k 0.7×	4.2k 2.5×	55 0.1×	53 0.1×	369 1.1×	328	8.9k
Markus Y. Mapara United States	35	1.8k 0.9×	2.5k 1.5×	164 0.4×	25 0.1×	163 0.5×	174	5.0k

Countries citing papers authored by Stephan Ruetz

Since Specialization

Citations

This map shows the geographic impact of Stephan Ruetz's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Stephan Ruetz with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Stephan Ruetz more than expected).

Fields of papers citing papers by Stephan Ruetz

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Stephan Ruetz. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Stephan Ruetz. The network helps show where Stephan Ruetz may publish in the future.

Co-authorship network of co-authors of Stephan Ruetz

This figure shows the co-authorship network connecting the top 25 collaborators of Stephan Ruetz. A scholar is included among the top collaborators of Stephan Ruetz based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Stephan Ruetz. Stephan Ruetz is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Vaupel, Andrea, Philipp Holzer, Stéphane Ferretti, et al.. (2018). In vitro and in vivo characterization of a novel, highly potent p53-MDM2 inhibitor. Bioorganic & Medicinal Chemistry Letters. 28(20). 3404–3408. 16 indexed citations

Gessier, F., Joerg Kallen, Edgar Jacoby, et al.. (2015). Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53–MDM2 interaction with a distinct binding mode. Bioorganic & Medicinal Chemistry Letters. 25(17). 3621–3625. 47 indexed citations

Holzer, Philipp, Keiichi Masuya, Pascal Furet, et al.. (2015). Discovery of a Dihydroisoquinolinone Derivative (NVP-CGM097): A Highly Potent and Selective MDM2 Inhibitor Undergoing Phase 1 Clinical Trials in p53wt Tumors. Journal of Medicinal Chemistry. 58(16). 6348–6358. 152 indexed citations

Massey, Andrew J., Joseph Schoepfer, Paul A. Brough, et al.. (2010). Preclinical Antitumor Activity of the Orally Available Heat Shock Protein 90 Inhibitor NVP-BEP800. Molecular Cancer Therapeutics. 9(4). 906–919. 50 indexed citations

McSheehy, Paul M.J., Claudia Weidensteiner, Catherine Cannet, et al.. (2009). Quantified Tumor T1 Is a Generic Early-Response Imaging Biomarker for Chemotherapy Reflecting Cell Viability. Clinical Cancer Research. 16(1). 212–225. 47 indexed citations

Ruetz, Stephan, et al.. (2007). Cis‐Stilbene Derived Furopyranones Show Potent Antiproliferative Activity by Inducing G2/M Arrest. ChemMedChem. 2(4). 441–444. 5 indexed citations

Beuvink, Iwan, Anne Boulay, Stefano Fumagalli, et al.. (2005). The mTOR Inhibitor RAD001 Sensitizes Tumor Cells to DNA-Damaged Induced Apoptosis through Inhibition of p21 Translation. Cell. 120(6). 747–759. 426 indexed citations

Garcı́a-Echeverrı́a, Carlos, Mark Pearson, Andreas Marti, et al.. (2004). In vivo antitumor activity of NVP-AEW541—A novel, potent, and selective inhibitor of the IGF-IR kinase. Cancer Cell. 5(3). 231–239. 447 indexed citations

Ruetz, Stephan, François Natt, Jonathan Hall, et al.. (2004). The human ubiquitin-conjugating enzyme Cdc34 controls cellular proliferation through regulation of p27Kip1 protein levels. Experimental Cell Research. 303(2). 482–493. 22 indexed citations

10.

Beuvink, Iwan, Anne Boulay, Stefano Fumagalli, et al.. (2004). 40 RAD001 sensitizes tumor cells to cisplatin-induced apoptosis in an mTOR dependent manner by inhibition of p53-induced p21 protein expression. European Journal of Cancer Supplements. 2(8). 16–16. 1 indexed citations

11.

Ruetz, Stephan, Doriano Fabbro, Juerg Zimmermann, Thomas Meyer, & Nathanael S. Gray. (2003). Chemical and Biological Profile of Dual Cdk1 and Cdk2 Inhibitors. PubMed. 3(1). 1–14. 32 indexed citations

12.

Garcı́a-Echeverrı́a, Carlos & Stephan Ruetz. (2003). β-Homolysine Oligomers: A New Class of Trojan Carriers. Bioorganic & Medicinal Chemistry Letters. 13(2). 247–251. 19 indexed citations

13.

Ruetz, Stephan. (1998). [28] Yeast secretory vesicle system for expression and functional characterization of P-glycoproteins. Methods in enzymology on CD-ROM/Methods in enzymology. 292. 382–396. 5 indexed citations

14.

Sardini, Alessandro, Stephan Ruetz, Richard Callaghan, et al.. (1996). Protein Kinase C-mediated Phosphorylation Does Not Regulate Drug Transport by the Human Multidrug Resistance P-glycoprotein. Journal of Biological Chemistry. 271(23). 13668–13674. 110 indexed citations

15.

Ruetz, Stephan & Philippe Gros. (1995). Enhancement of Mdr2-mediated Phosphatidylcholine Translocation by the Bile Salt Taurocholate. Journal of Biological Chemistry. 270(43). 25388–25395. 75 indexed citations

16.

Raymond, Martine, Stephan Ruetz, David Y. Thomas, & Piet Gros. (1994). Functional expression of P-glycoprotein in Saccharomyces cerevisiae confers cellular resistance to the immunosuppressive and antifungal agent FK520. Molecular and Cellular Biology. 14(1). 277–286. 10 indexed citations

17.

Ruetz, Stephan. (1994). Phosphatidylcholine translocase: A physiological role for the mdr2 gene. Cell. 77(7). 1071–1081. 509 indexed citations breakdown →

18.

Ruetz, Stephan & Philippe Gros. (1994). A mechanism for P-glycoprotein action in multidrug resistance: are we there yet?. Trends in Pharmacological Sciences. 15(7). 260–263. 44 indexed citations

19.

Ruetz, Stephan, M Raymond, & Philippe Gros. (1993). Functional expression of P-glycoprotein encoded by the mouse mdr3 gene in yeast cells.. Proceedings of the National Academy of Sciences. 90(24). 11588–11592. 41 indexed citations

20.

Ruetz, Stephan, Gert Fricker, G. Hugentobler, et al.. (1987). Isolation and characterization of the putative canalicular bile salt transport system of rat liver.. Journal of Biological Chemistry. 262(23). 11324–11330. 80 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact