Henrik Möbitz

1.6k total citations
26 papers, 833 citations indexed

About

Henrik Möbitz is a scholar working on Molecular Biology, Computational Theory and Mathematics and Oncology. According to data from OpenAlex, Henrik Möbitz has authored 26 papers receiving a total of 833 indexed citations (citations by other indexed papers that have themselves been cited), including 22 papers in Molecular Biology, 6 papers in Computational Theory and Mathematics and 5 papers in Oncology. Recurrent topics in Henrik Möbitz's work include Computational Drug Discovery Methods (6 papers), Melanoma and MAPK Pathways (5 papers) and Cancer-related gene regulation (5 papers). Henrik Möbitz is often cited by papers focused on Computational Drug Discovery Methods (6 papers), Melanoma and MAPK Pathways (5 papers) and Cancer-related gene regulation (5 papers). Henrik Möbitz collaborates with scholars based in Switzerland, Germany and United States. Henrik Möbitz's co-authors include Sandra W. Cowan‐Jacob, Doriano Fabbro, Matthias Boll, Georg Martiny‐Baron, Clemens Scheufler, Rainer Machauer, Heinrich Rueeger, Sandrine Desrayaud, Ulf Neumann and Jean‐Michel Rondeau and has published in prestigious journals such as Journal of Biological Chemistry, Biochemistry and Cancer Research.

In The Last Decade

Henrik Möbitz

25 papers receiving 808 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Henrik Möbitz Switzerland 17 551 167 162 134 79 26 833
Mark R. Witmer United States 16 378 0.7× 116 0.7× 108 0.7× 104 0.8× 57 0.7× 29 893
Manuela Gridling Austria 13 672 1.2× 126 0.8× 74 0.5× 269 2.0× 43 0.5× 17 1.0k
Y. Amano Japan 18 474 0.9× 195 1.2× 114 0.7× 70 0.5× 108 1.4× 35 814
Nicole Caspers United States 15 490 0.9× 231 1.4× 116 0.7× 113 0.8× 87 1.1× 19 809
Nathaniel J. Henning United States 8 647 1.2× 272 1.6× 104 0.6× 211 1.6× 39 0.5× 10 861
M.A. Argiriadi United States 13 357 0.6× 161 1.0× 53 0.3× 178 1.3× 35 0.4× 22 971
Wen‐Hsing Lin Taiwan 19 569 1.0× 212 1.3× 104 0.6× 260 1.9× 37 0.5× 45 987
Chad N. Hancock United States 12 1.0k 1.9× 77 0.5× 60 0.4× 252 1.9× 35 0.4× 16 1.4k
Norbert Furtmann Germany 16 337 0.6× 325 1.9× 142 0.9× 111 0.8× 97 1.2× 31 701
Ribo Guo United States 14 904 1.6× 193 1.2× 78 0.5× 261 1.9× 68 0.9× 18 1.2k

Countries citing papers authored by Henrik Möbitz

Since Specialization
Citations

This map shows the geographic impact of Henrik Möbitz's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Henrik Möbitz with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Henrik Möbitz more than expected).

Fields of papers citing papers by Henrik Möbitz

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Henrik Möbitz. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Henrik Möbitz. The network helps show where Henrik Möbitz may publish in the future.

Co-authorship network of co-authors of Henrik Möbitz

This figure shows the co-authorship network connecting the top 25 collaborators of Henrik Möbitz. A scholar is included among the top collaborators of Henrik Möbitz based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Henrik Möbitz. Henrik Möbitz is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Möbitz, Henrik, et al.. (2024). Nonclassical Zwitterions as a Design Principle to Reduce Lipophilicity without Impacting Permeability. Journal of Medicinal Chemistry. 67(11). 9485–9494. 2 indexed citations
2.
Blank, Jutta, Dirk Erdmann, Patrizia Fontana, et al.. (2024). Challenges for the Discovery of Non‐Covalent WRN Helicase Inhibitors. ChemMedChem. 19(8). e202300613–e202300613. 13 indexed citations
3.
4.
Möbitz, Henrik. (2023). Design Principles for Balancing Lipophilicity and Permeability in beyond Rule of 5 Space. ChemMedChem. 19(5). e202300395–e202300395. 8 indexed citations
5.
Argikar, Upendra A., Markus Blatter, Dallas Bednarczyk, et al.. (2022). Paradoxical Increase of Permeability and Lipophilicity with the Increasing Topological Polar Surface Area within a Series of PRMT5 Inhibitors. Journal of Medicinal Chemistry. 65(18). 12386–12402. 9 indexed citations
6.
Weiss, Andreas, Frédéric Stauffer, Henrik Möbitz, et al.. (2020). Abstract 1770: A new DOT1L inhibitor with in vivo activity in mouse models of MLL-translocated leukemia. Cancer Research. 80(16_Supplement). 1770–1770.
7.
Stauffer, Frédéric, Andreas Weiss, Clemens Scheufler, et al.. (2019). New Potent DOT1L Inhibitors for in Vivo Evaluation in Mouse. ACS Medicinal Chemistry Letters. 10(12). 1655–1660. 27 indexed citations
8.
Möbitz, Henrik, Rainer Machauer, Philipp Holzer, et al.. (2017). Discovery of Potent, Selective, and Structurally Novel Dot1L Inhibitors by a Fragment Linking Approach. ACS Medicinal Chemistry Letters. 8(3). 338–343. 42 indexed citations
9.
Chen, Chao, Hugh Zhu, Frédéric Stauffer, et al.. (2016). Discovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation Approach. ACS Medicinal Chemistry Letters. 7(8). 735–740. 51 indexed citations
10.
Möbitz, Henrik, Wolfgang Jahnke, & Sandra W. Cowan‐Jacob. (2016). Expanding the Opportunities for Modulating Kinase Targets with Allosteric Approaches. Current Topics in Medicinal Chemistry. 17(1). 59–70. 13 indexed citations
11.
Möbitz, Henrik. (2015). The ABC of protein kinase conformations. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1854(10). 1555–1566. 68 indexed citations
12.
Gutmann, Sascha, Alexandra Hinniger, Gabriele Fendrich, et al.. (2015). The Crystal Structure of Cancer Osaka Thyroid Kinase Reveals an Unexpected Kinase Domain Fold. Journal of Biological Chemistry. 290(24). 15210–15218. 14 indexed citations
13.
Rueeger, Heinrich, Rainer Machauer, Laura H. Jacobson, et al.. (2013). Discovery of cyclic sulfoxide hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors: Structure based design and in vivo reduction of amyloid β-peptides. Bioorganic & Medicinal Chemistry Letters. 23(19). 5300–5306. 22 indexed citations
14.
Rueeger, Heinrich, Jean‐Michel Rondeau, Clive McCarthy, et al.. (2011). Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors. Bioorganic & Medicinal Chemistry Letters. 21(7). 1942–1947. 32 indexed citations
15.
Fabbro, Doriano, Sandra W. Cowan‐Jacob, Henrik Möbitz, & Georg Martiny‐Baron. (2011). Targeting Cancer with Small-Molecular-Weight Kinase Inhibitors. Methods in molecular biology. 795. 1–34. 95 indexed citations
16.
Révész, Láśzló, Achim Schlapbach, Reiner Aichholz, et al.. (2010). In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inhibitors. Part I. Bioorganic & Medicinal Chemistry Letters. 20(15). 4715–4718. 23 indexed citations
17.
Révész, Láśzló, Achim Schlapbach, Reiner Aichholz, et al.. (2010). In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inhibitors. Part II. Bioorganic & Medicinal Chemistry Letters. 20(15). 4719–4723. 27 indexed citations
18.
Cowan‐Jacob, Sandra W., Henrik Möbitz, & Doriano Fabbro. (2009). Structural biology contributions to tyrosine kinase drug discovery. Current Opinion in Cell Biology. 21(2). 280–287. 41 indexed citations
19.
Möbitz, Henrik, Thorsten Friedrich, & Matthias Boll. (2004). Substrate Binding and Reduction of Benzoyl-CoA Reductase:  Evidence for Nucleotide-Dependent Conformational Changes. Biochemistry. 43(5). 1376–1385. 14 indexed citations
20.
Möbitz, Henrik & Thomas C. Bruice. (2004). Multiple Substrate Binding States and Chiral Recognition in Cofactor-independent Glutamate Racemase:  A Molecular Dynamics Study. Biochemistry. 43(30). 9685–9694. 18 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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