Patrick Chêne

7.8k total citations · 2 hit papers
102 papers, 5.1k citations indexed

About

Patrick Chêne is a scholar working on Molecular Biology, Oncology and Cell Biology. According to data from OpenAlex, Patrick Chêne has authored 102 papers receiving a total of 5.1k indexed citations (citations by other indexed papers that have themselves been cited), including 64 papers in Molecular Biology, 40 papers in Oncology and 31 papers in Cell Biology. Recurrent topics in Patrick Chêne's work include Cancer-related Molecular Pathways (34 papers), Hippo pathway signaling and YAP/TAZ (20 papers) and RNA modifications and cancer (15 papers). Patrick Chêne is often cited by papers focused on Cancer-related Molecular Pathways (34 papers), Hippo pathway signaling and YAP/TAZ (20 papers) and RNA modifications and cancer (15 papers). Patrick Chêne collaborates with scholars based in Switzerland, United Kingdom and United States. Patrick Chêne's co-authors include Pascal Furet, Carlos Garcı́a-Echeverrı́a, Josef Brueggen, Doriano Fabbro, William R. Sellers, Alain De Pover, Christian Schnell, Christine Fritsch, Marjo Simonen and Daniela Gabriel and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Angewandte Chemie International Edition.

In The Last Decade

Patrick Chêne

99 papers receiving 5.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity

2008 954 citations Sauveur-Michel Maira, Frédéric Stauffer et al. Molecular Cancer Therapeutics profile →
Inhibiting the p53–MDM2 interaction: an important target for cancer therapy

2003 578 citations Patrick Chêne Nature reviews. Cancer profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Patrick Chêne Switzerland	30	3.9k	2.0k	731	676	491	102	5.1k
Christine Lukacs United States	21	3.9k 1.0×	2.5k 1.3×	484 0.7×	625 0.9×	637 1.3×	35	5.3k
Nader Fotouhi United States	19	3.3k 0.9×	2.3k 1.2×	388 0.5×	629 0.9×	547 1.1×	47	4.7k
U. Kammlott United States	7	3.1k 0.8×	2.3k 1.2×	383 0.5×	522 0.8×	520 1.1×	8	4.0k
Binh Thanh Vu Vietnam	17	4.2k 1.1×	3.4k 1.7×	529 0.7×	742 1.1×	733 1.5×	48	5.8k
Nancy E. Kohl United States	42	5.2k 1.3×	2.4k 1.2×	820 1.1×	757 1.1×	843 1.7×	97	8.0k
Bradford Graves United States	26	5.2k 1.3×	3.6k 1.8×	601 0.8×	1.1k 1.7×	778 1.6×	45	7.3k
Laura Sepp‐Lorenzino United States	36	3.6k 0.9×	1.0k 0.5×	517 0.7×	732 1.1×	788 1.6×	78	4.9k
Sridhar K. Rabindran United States	29	3.5k 0.9×	2.5k 1.3×	403 0.6×	854 1.3×	506 1.0×	45	5.7k
Shiro Akinaga Japan	43	3.7k 1.0×	1.8k 0.9×	646 0.9×	470 0.7×	381 0.8×	122	6.6k
Catherine L. Day New Zealand	38	6.1k 1.6×	1.8k 0.9×	543 0.7×	328 0.5×	745 1.5×	81	7.4k

Countries citing papers authored by Patrick Chêne

Since Specialization

Citations

This map shows the geographic impact of Patrick Chêne's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Patrick Chêne with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Patrick Chêne more than expected).

Fields of papers citing papers by Patrick Chêne

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Patrick Chêne. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Patrick Chêne. The network helps show where Patrick Chêne may publish in the future.

Co-authorship network of co-authors of Patrick Chêne

This figure shows the co-authorship network connecting the top 25 collaborators of Patrick Chêne. A scholar is included among the top collaborators of Patrick Chêne based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Patrick Chêne. Patrick Chêne is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Bokhovchuk, Fedir, et al.. (2022). Long-range structural preformation in yes-associated protein precedes encounter complex formation with TEAD. iScience. 25(4). 104099–104099. 7 indexed citations

Bokhovchuk, Fedir, Yannick Mesrouze, Marco Meyerhofer, et al.. (2019). Molecular and structural characterization of a TEAD mutation at the origin of Sveinsson's chorioretinal atrophy. FEBS Journal. 286(12). 2381–2398. 21 indexed citations

Platzer, Gerald, et al.. (2018). 1H, 13C, 15N resonance assignment of human YAP 50–171 fragment. Biomolecular NMR Assignments. 12(1). 179–182. 9 indexed citations

Erdmann, Dirk, Yannick Mesrouze, Pascal Furet, et al.. (2013). The TEAD4–YAP/TAZ Protein–Protein Interaction: Expected Similarities and Unexpected Differences. ChemBioChem. 14(10). 1218–1225. 59 indexed citations

Furet, Pascal, Patrick Chêne, Alain De Pover, et al.. (2012). The central valine concept provides an entry in a new class of non peptide inhibitors of the p53–MDM2 interaction. Bioorganic & Medicinal Chemistry Letters. 22(10). 3498–3502. 52 indexed citations

Chêne, Patrick. (2012). Can biochemistry drive drug discovery beyond simple potency measurements?. Drug Discovery Today. 17(7-8). 388–395. 5 indexed citations

Massey, Andrew J., Joseph Schoepfer, Paul A. Brough, et al.. (2010). Preclinical Antitumor Activity of the Orally Available Heat Shock Protein 90 Inhibitor NVP-BEP800. Molecular Cancer Therapeutics. 9(4). 906–919. 50 indexed citations

Maira, Sauveur-Michel, Frédéric Stauffer, Josef Brueggen, et al.. (2008). Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity. Molecular Cancer Therapeutics. 7(7). 1851–1863. 954 indexed citations breakdown →

Cechowska‐Pasko, Marzanna, Patrick Chêne, & E Bańkowski. (2006). The Effect of Hypoxia on the Expression of 150 kDa Oxygen-regulated Protein (ORP 150) in HeLa Cells. Cellular Physiology and Biochemistry. 17(1-2). 89–96. 23 indexed citations

10.

Chêne, Patrick. (2006). Drugs Targeting Protein–Protein Interactions. ChemMedChem. 1(4). 400–411. 99 indexed citations

11.

Dubaele, Sandy, et al.. (2006). Study of the ATP-binding site of helicase IV from Escherichia coli. Biochemical and Biophysical Research Communications. 341(3). 828–836. 2 indexed citations

12.

Xu, Ting, Aruna Sampath, Alex Chao, et al.. (2006). Towards the Design of Flavivirus Helicase/NTPase Inhibitors: Crystallographic and Mutagenesis Studies of the Dengue Virus NS3 Helicase Catalytic Domain. Novartis Foundation symposium. 277. 87–101. 19 indexed citations

13.

Chêne, Patrick. (2003). Inhibiting the p53–MDM2 interaction: an important target for cancer therapy. Nature reviews. Cancer. 3(2). 102–109. 578 indexed citations breakdown →

14.

Chêne, Patrick, et al.. (2002). The gain of function of the p53 mutant Asp281Gly is dependent on its ability to form tetramers. Cancer Letters. 185(1). 103–109. 12 indexed citations

15.

Banerjee, Raja, Gautam Basu, Siddhartha Roy, & Patrick Chêne. (2002). Aib‐based peptide backbone as scaffolds for helical peptide mimics. Journal of Peptide Research. 60(2). 88–94. 65 indexed citations

16.

Garcı́a-Echeverrı́a, Carlos, Pascal Furet, & Patrick Chêne. (2001). Coupling of the antennapedia third helix to a potent antagonist of the p53/hdm2 protein–protein interaction. Bioorganic & Medicinal Chemistry Letters. 11(16). 2161–2164. 12 indexed citations

17.

Rollenhagen, Christiane & Patrick Chêne. (1998). Characterization ofp53 mutants identified in human tumors with a missense mutation in the tetramerization domain. International Journal of Cancer. 78(3). 372–376. 23 indexed citations

18.

Chêne, Patrick. (1998). In vitro analysis of the dominant negative effect of p53 mutants. Journal of Molecular Biology. 281(2). 205–209. 57 indexed citations

19.

Chêne, Patrick, Anthony G. Day, & Alan R. Fersht. (1997). Role of Isoleucine-164 at the Active Site of Rubisco fromRhodospirillum rubrum. Biochemical and Biophysical Research Communications. 232(2). 482–486. 10 indexed citations

20.

Chêne, Patrick, et al.. (1992). Microtubule assembly protects the region 28–38 of the β‐ tubulin subunit. Cell Motility and the Cytoskeleton. 22(1). 25–37. 8 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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