Standout Papers

Death Receptors: Signaling and Modulation 1995 2026 2005 2015 4.8k
  1. Death Receptors: Signaling and Modulation (1998)
    Avi Ashkenazi, Vishva M. Dixit Science
  2. FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex (1996)
    Marta Muzio, Arul M. Chinnaiyan et al. Cell
  3. Cryopyrin activates the inflammasome in response to toxins and ATP (2006)
    Sanjeev Mariathasan, David S. Weiss et al. Nature
  4. Inflammasomes: mechanism of assembly, regulation and signalling (2016)
    Petr Brož, Vishva M. Dixit Nature reviews. Immunology
  5. Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase (1995)
    Muneesh Tewari, Long T. Quan et al. Cell
  6. FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis (1995)
    Arul M. Chinnaiyan, Karen O’Rourke et al. Cell
  7. Non-canonical inflammasome activation targets caspase-11 (2011)
    Nobuhiko Kayagaki, Søren Warming et al. Nature
  8. Mechanisms and Functions of Inflammasomes (2014)
    Mohamed Lamkanfi, Vishva M. Dixit Cell
  9. Caspases: Intracellular Signaling by Proteolysis (1997)
    Guy S. Salvesen, Vishva M. Dixit Cell
  10. Vascular Endothelial Growth Factor Regulates Endothelial Cell Survival through the Phosphatidylinositol 3′-Kinase/Akt Signal Transduction Pathway (1998)
    Hans-Peter Gerber, Joe Kowalski et al. Journal of Biological Chemistry
  11. The Receptor for the Cytotoxic Ligand TRAIL (1997)
    Guohua Pan, Karen O’Rourke et al. Science
  12. De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling (2004)
    Ingrid E. Wertz, Karen O’Rourke et al. Nature
  13. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf (2004)
    Sanjeev Mariathasan, Kim Newton et al. Nature
  14. An Antagonist Decoy Receptor and a Death Domain-Containing Receptor for TRAIL (1997)
    Guohua Pan, Jian Ni et al. Science
  15. Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4 (2013)
    Nobuhiko Kayagaki, Michael T. Wong et al. Science
  16. Apoptosis Signaling (2000)
    Andreas Strasser, Liam O’Connor et al. Annual Review of Biochemistry
  17. Signaling in Innate Immunity and Inflammation (2012)
    Kim Newton, Vishva M. Dixit Cold Spring Harbor Perspectives in Biology
  18. Apoptosis control by death and decoy receptors (1999)
    Avi Ashkenazi, Vishva M. Dixit Current Opinion in Cell Biology
  19. IAP Antagonists Induce Autoubiquitination of c-IAPs, NF-κB Activation, and TNFα-Dependent Apoptosis (2007)
    Eugene Varfolomeev, John W. Blankenship et al. Cell
  20. IRAK (Pelle) Family Member IRAK-2 and MyD88 as Proximal Mediators of IL-1 Signaling (1997)
    Marta Muzio, Jian Ni et al. Science
  21. TRAF2-Mediated Activation of NF-κB by TNF Receptor 2 and CD40 (1995)
    Mike Rothe, Vidya Sarma et al. Science
  22. An Induced Proximity Model for Caspase-8 Activation (1998)
    Marta Muzio, Brent R. Stockwell et al. Journal of Biological Chemistry
  23. Vascular Endothelial Growth Factor Induces Expression of the Antiapoptotic Proteins Bcl-2 and A1 in Vascular Endothelial Cells (1998)
    Hans‐Peter Gerber, Vishva M. Dixit et al. Journal of Biological Chemistry
  24. Inflammasomes and Their Roles in Health and Disease (2012)
    Mohamed Lamkanfi, Vishva M. Dixit Annual Review of Cell and Developmental Biology
  25. Caspase activation: The induced-proximity model (1999)
    Guy S. Salvesen, Vishva M. Dixit Proceedings of the National Academy of Sciences
  26. GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes (2016)
    Alberto Estevez, Peter S. Liu et al. Proceedings of the National Academy of Sciences
  27. Glyburide inhibits the Cryopyrin/Nalp3 inflammasome (2009)
    Mohamed Lamkanfi, James L. Mueller et al. The Journal of Cell Biology
  28. FADD/MORT1 Is a Common Mediator of CD95 (Fas/APO-1) and Tumor Necrosis Factor Receptor-induced Apoptosis (1996)
    Arul M. Chinnaiyan, Clifford G. Tepper et al. Journal of Biological Chemistry
  29. Keratinocytes as initiators of inflammation (1991)
    Juliet N. Barker, C.E.M. Griffiths et al. The Lancet
  30. Mitochondrial reactive oxygen species drive proinflammatory cytokine production (2011)
    Edwina Naik, Vishva M. Dixit The Journal of Experimental Medicine
  31. The ubiquitin ligase COP1 is a critical negative regulator of p53 (2004)
    David Dornan, Ingrid E. Wertz et al. Nature
  32. Signal Transduction by DR3, a Death Domain-Containing Receptor Related to TNFR-1 and CD95 (1996)
    Arul M. Chinnaiyan, Karen O’Rourke et al. Science
  33. Molecular Ordering of the Cell Death Pathway (1996)
    Arul M. Chinnaiyan, Kim Orth et al. Journal of Biological Chemistry
  34. Interaction of CED-4 with CED-3 and CED-9: A Molecular Framework for Cell Death (1997)
    Arul M. Chinnaiyan, Karen O’Rourke et al. Science
  35. Fas- and Tumor Necrosis Factor-induced Apoptosis Is Inhibited by the Poxvirus crmA Gene Product (1995)
    Muneesh Tewari, Vishva M. Dixit Journal of Biological Chemistry
  36. Activity of Protein Kinase RIPK3 Determines Whether Cells Die by Necroptosis or Apoptosis (2014)
    Kim Newton, Debra L. Dugger et al. Science
  37. Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival (2009)
    Martin Schwickart, Xiaodong Huang et al. Nature
  38. Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense againstSalmonella (2010)
    Petr Brož, Kim Newton et al. The Journal of Experimental Medicine
  39. Cell death (2024)
    Kim Newton, Andreas Strasser et al. Cell
  40. Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis (2019)
    Kim Newton, Katherine E. Wickliffe et al. Nature
  41. Fiery Cell Death: Pyroptosis in the Central Nervous System (2019)
    Brienne McKenzie, Vishva M. Dixit et al. Trends in Neurosciences

Immediate Impact

27 by Nobel laureates 123 from Science/Nature 332 standout
Sub-graph 1 of 10

Citing Papers

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
2017 StandoutNature
Inflammasomes in health and disease
2012 StandoutNature
261 intermediate papers

Works of Vishva M. Dixit being referenced

Cryopyrin activates the inflammasome in response to toxins and ATP
2006 StandoutNature
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
2004 StandoutNature
and 76 more

Author Peers

Author Last Decade Papers Cites
Vishva M. Dixit 61633 32645 15634 312 86.9k
Tak W. Mak 49026 33684 16886 703 94.7k
Stanley J. Korsmeyer 59060 15078 7600 230 83.2k
Jürg Tschopp 51322 42911 7960 282 86.1k
Douglas R. Green 79879 34890 14932 605 123.0k
John C. Reed 72596 20246 12113 788 106.2k
Peter Vandenabeele 36202 20547 8299 449 60.6k
David V. Goeddel 34538 24057 16576 192 64.2k
Andreas Strasser 36764 18604 7433 476 57.4k
Gabriel Núñez 47173 33855 6432 407 83.1k
Frederick W. Alt 41129 26758 6786 482 72.9k

All Works

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