Sofie Struyf

17.2k total citations · 3 hit papers
207 papers, 13.9k citations indexed

About

Sofie Struyf is a scholar working on Oncology, Immunology and Molecular Biology. According to data from OpenAlex, Sofie Struyf has authored 207 papers receiving a total of 13.9k indexed citations (citations by other indexed papers that have themselves been cited), including 119 papers in Oncology, 105 papers in Immunology and 56 papers in Molecular Biology. Recurrent topics in Sofie Struyf's work include Chemokine receptors and signaling (110 papers), Immunotherapy and Immune Responses (47 papers) and Cell Adhesion Molecules Research (42 papers). Sofie Struyf is often cited by papers focused on Chemokine receptors and signaling (110 papers), Immunotherapy and Immune Responses (47 papers) and Cell Adhesion Molecules Research (42 papers). Sofie Struyf collaborates with scholars based in Belgium, Saudi Arabia and Italy. Sofie Struyf's co-authors include Jo Van Damme, Paul Proost, Ghislain Opdenakker, Evemie Schutyser, Mieke Gouwy, Jo Vandercappellen, Dominique Schols, Erik De Clercq, Rik Janssens and Marc Parmentier and has published in prestigious journals such as Journal of Biological Chemistry, Journal of Clinical Investigation and The Journal of Experimental Medicine.

In The Last Decade

Sofie Struyf

202 papers receiving 13.7k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Functional Characterization of Human Receptors for Short Chain Fatty Acids and Their Role in Polymorphonuclear Cell Activation

2003 1.3k citations Emmanuel Le Poul, Sofie Struyf et al. Journal of Biological Chemistry profile →
The CC chemokine CCL20 and its receptor CCR6

2003 644 citations Evemie Schutyser, Sofie Struyf et al. Cytokine & Growth Factor Reviews profile →
The role of CXC chemokines and their receptors in cancer

2008 520 citations Jo Vandercappellen, Jo Van Damme et al. profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author						Papers	Cites
Sofie Struyf	6.0k	5.5k	4.2k	1.1k	1.1k	207	13.9k
Christophe Combadière	7.7k 1.3×	3.8k 0.7×	2.6k 0.6×	730 0.6×	903 0.8×	166	13.0k
William A. Kuziel	7.7k 1.3×	2.9k 0.5×	3.1k 0.7×	637 0.6×	868 0.8×	125	13.9k
Jonathon D. Sedgwick	10.5k 1.7×	2.6k 0.5×	2.0k 0.5×	937 0.8×	1.3k 1.2×	98	15.0k
Thomas Brunner	5.9k 1.0×	2.1k 0.4×	5.8k 1.4×	1.1k 0.9×	1.6k 1.5×	171	13.8k
Barrett J. Rollins	10.8k 1.8×	8.0k 1.5×	6.0k 1.4×	2.2k 1.9×	2.3k 2.2×	126	23.0k
Tetsuji Naka	6.4k 1.1×	5.1k 0.9×	3.7k 0.9×	358 0.3×	741 0.7×	202	13.4k
Kazuyuki Yoshizaki	4.4k 0.7×	4.5k 0.8×	2.7k 0.6×	246 0.2×	1.0k 1.0×	143	12.2k
Teizo Yoshimura	8.6k 1.4×	4.8k 0.9×	5.4k 1.3×	2.4k 2.1×	1.4k 1.3×	318	17.8k
Alfons Billiau	6.7k 1.1×	3.3k 0.6×	3.3k 0.8×	963 0.8×	817 0.8×	267	13.4k
René E. M. Toes	15.6k 2.6×	5.0k 0.9×	6.5k 1.5×	1.3k 1.1×	1.0k 1.0×	490	30.9k

Countries citing papers authored by Sofie Struyf

Since Specialization

Citations

This map shows the geographic impact of Sofie Struyf's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sofie Struyf with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sofie Struyf more than expected).

Fields of papers citing papers by Sofie Struyf

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sofie Struyf. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sofie Struyf. The network helps show where Sofie Struyf may publish in the future.

Co-authorship network of co-authors of Sofie Struyf

This figure shows the co-authorship network connecting the top 25 collaborators of Sofie Struyf. A scholar is included among the top collaborators of Sofie Struyf based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sofie Struyf. Sofie Struyf is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Ehlers, Lisa, Selket Delafontaine, Rik Schrijvers, et al.. (2025). Dominant negative ADA2 mutations cause ADA2 deficiency in heterozygous carriers. The Journal of Experimental Medicine. 222(11).

Blanter, Marfa, Mieke Gouwy, Natalie Lorent, et al.. (2024). Inhibiting CFTR through inh-172 in primary neutrophils reveals CFTR-specific functional defects. Scientific Reports. 14(1). 31237–31237. 1 indexed citations

Struyf, Sofie, et al.. (2024). Inhibitors of Bruton's tyrosine kinase as emerging therapeutic strategy in autoimmune diseases. Autoimmunity Reviews. 23(5). 103532–103532. 6 indexed citations

Berghmans, Nele, Noëmie Pörtner, Vívian Louise Soares de Oliveira, et al.. (2024). Effect on neutrophil migration and antimicrobial functions by the Bruton's tyrosine kinase inhibitors tolebrutinib, evobrutinib, and fenebrutinib. Journal of Leukocyte Biology. 117(3). 4 indexed citations

Damme, Jo Van, et al.. (2023). Antibodies as tools in cytokine discovery and usage for diagnosis and therapy of inflammatory diseases. European Cytokine Network. 34(1). 1–9. 2 indexed citations

Soebadi, Mohammad Ayodhia, Mieke Metzemaekers, Nele Berghmans, et al.. (2022). Inhibition of renal fibrosis with a human CXCL9‐derived glycosaminoglycan‐binding peptide. Clinical & Translational Immunology. 11(2). e1370–e1370. 2 indexed citations

Berghmans, Nele, Sam Noppen, Erik Martens, et al.. (2022). A stabilized CXCL9(74–103)-derived peptide selectively inhibits proliferation, adhesion and metastasis of tumor cells that express high levels of heparan sulfate. International Journal of Biological Macromolecules. 222(Pt B). 2808–2822. 3 indexed citations

Damme, Jo Van, et al.. (2021). The Role of Post-Translational Modifications of Chemokines by CD26 in Cancer. Cancers. 13(17). 4247–4247. 15 indexed citations

Berghmans, Nele, Melissa García‐Caballero, Noëmie Pörtner, et al.. (2021). The Chemokine-Based Peptide, CXCL9(74-103), Inhibits Angiogenesis by Blocking Heparan Sulfate Proteoglycan-Mediated Signaling of Multiple Endothelial Growth Factors. Cancers. 13(20). 5090–5090. 15 indexed citations

10.

Cambier, Seppe, Noëmie Pörtner, Sofie Struyf, et al.. (2021). Affinity and Specificity for Binding to Glycosaminoglycans Can Be Tuned by Adapting Peptide Length and Sequence. International Journal of Molecular Sciences. 23(1). 447–447. 11 indexed citations

11.

Hellings, Niels, et al.. (2020). Neutrophils: Underestimated Players in the Pathogenesis of Multiple Sclerosis (MS). International Journal of Molecular Sciences. 21(12). 4558–4558. 73 indexed citations

12.

Gouwy, Mieke, Noëmie Pörtner, Nele Berghmans, et al.. (2020). Induction of Chemokines by Hepatitis C Virus Proteins: Synergy of the Core Protein with Interleukin-1β and Interferon-γ in Liver Bystander Cells. Journal of Interferon & Cytokine Research. 40(4). 195–206. 4 indexed citations

13.

Collins, Paul J., Mieke Metzemaekers, Max Meyrath, et al.. (2020). CXCL14 Preferentially Synergizes With Homeostatic Chemokine Receptor Systems. Frontiers in Immunology. 11. 561404–561404. 22 indexed citations

14.

Buck, Mieke De, Mieke Gouwy, Ji Ming Wang, et al.. (2015). The cytokine-serum amyloid A-chemokine network. Cytokine & Growth Factor Reviews. 30. 55–69. 112 indexed citations

15.

El‐Asrar, Ahmed M. Abu, Sofie Struyf, Dustan Kangave, et al.. (2011). Cytokine profiles in aqueous humor of patients with different clinical entities of endogenous uveitis. European Journal of Ophthalmology. 95 indexed citations

16.

Proost, Paul, Tamara Loos, Anneleen Mortier, et al.. (2008). Citrullination of CXCL8 by peptidylarginine deiminase alters receptor usage, prevents proteolysis, and dampens tissue inflammation. The Journal of Experimental Medicine. 205(9). 2085–2097. 149 indexed citations

17.

Struyf, Sofie, Marie D. Burdick, Elke Peeters, et al.. (2007). Platelet Factor-4 Variant Chemokine CXCL4L1 Inhibits Melanoma and Lung Carcinoma Growth and Metastasis by Preventing Angiogenesis. Cancer Research. 67(12). 5940–5948. 88 indexed citations

18.

Proost, Paul, Anneleen Mortier, Tamara Loos, et al.. (2007). Proteolytic processing of CXCL11 by CD13/aminopeptidase N impairs CXCR3 and CXCR7 binding and signaling and reduces lymphocyte and endothelial cell migration. Blood. 110(1). 37–44. 113 indexed citations

19.

Struyf, Sofie, Marie D. Burdick, Paul Proost, Jo Van Damme, & Robert M. Strieter. (2004). Platelets Release CXCL4L1, a Nonallelic Variant of the Chemokine Platelet Factor-4/CXCL4 and Potent Inhibitor of Angiogenesis. Circulation Research. 95(9). 855–857. 126 indexed citations

20.

Poul, Emmanuel Le, Sofie Struyf, Jean–Yves Springael, et al.. (2003). Functional Characterization of Human Receptors for Short Chain Fatty Acids and Their Role in Polymorphonuclear Cell Activation. Journal of Biological Chemistry. 278(28). 25481–25489. 1304 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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