Ryoko Okamoto

6.9k total citations · 4 hit papers
33 papers, 5.4k citations indexed

About

Ryoko Okamoto is a scholar working on Molecular Biology, Pathology and Forensic Medicine and Oncology. According to data from OpenAlex, Ryoko Okamoto has authored 33 papers receiving a total of 5.4k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Molecular Biology, 6 papers in Pathology and Forensic Medicine and 6 papers in Oncology. Recurrent topics in Ryoko Okamoto's work include Wnt/β-catenin signaling in development and cancer (6 papers), Cell Adhesion Molecules Research (5 papers) and Acute Myeloid Leukemia Research (4 papers). Ryoko Okamoto is often cited by papers focused on Wnt/β-catenin signaling in development and cancer (6 papers), Cell Adhesion Molecules Research (5 papers) and Acute Myeloid Leukemia Research (4 papers). Ryoko Okamoto collaborates with scholars based in United States, Japan and Singapore. Ryoko Okamoto's co-authors include Akira Yamaguchi, Roderick T. Bronson, Shogo Nomura, Yun Gao, Shusaku Yoshiki, Yukihiko Kitamura, Toshihisa Komori, Hideshi Yagi, Koichi Sasaki and Motohiko Sato and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Ryoko Okamoto

32 papers receiving 5.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Targeted Disruption of Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts

1997 3.6k citations Toshihisa Komori, Hideshi Yagi et al. Cell profile →
Glucocorticoids promote breast cancer metastasis

2019 296 citations Milan Obradović, Baptiste Hamelin et al. Nature profile →
Hepatic stellate cells suppress NK cell-sustained breast cancer dormancy

2021 208 citations Ana Luísa Correia, Joao C. Guimaraes et al. Nature profile →
Inferring and perturbing cell fate regulomes in human brain organoids

2022 145 citations Jonas Simon Fleck, Sophie Jansen et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Ryoko Okamoto United States	20	3.8k	1.5k	806	745	660	33	5.4k
Matthew J. Hilton United States	37	3.2k 0.8×	854 0.6×	1.4k 1.7×	665 0.9×	638 1.0×	88	5.3k
Florian Otto Germany	24	3.1k 0.8×	1.4k 0.9×	613 0.8×	814 1.1×	581 0.9×	35	4.9k
T. Michael Underhill Canada	44	2.9k 0.8×	611 0.4×	1.0k 1.2×	505 0.7×	685 1.0×	108	5.1k
Baruch Frenkel United States	41	3.1k 0.8×	1.2k 0.8×	371 0.5×	611 0.8×	851 1.3×	89	4.9k
Michael W. Starbuck United States	19	3.2k 0.8×	1.2k 0.8×	498 0.6×	423 0.6×	703 1.1×	24	4.8k
Suk‐Chul Bae South Korea	40	4.6k 1.2×	1.4k 1.0×	424 0.5×	1.0k 1.4×	398 0.6×	78	6.1k
Riko Nishimura Japan	51	5.7k 1.5×	2.3k 1.5×	1.2k 1.5×	1.3k 1.8×	745 1.1×	126	8.4k
Steven N. Popoff United States	35	2.4k 0.6×	747 0.5×	628 0.8×	344 0.5×	433 0.7×	98	4.0k
Kana Miyamoto Japan	31	2.9k 0.8×	1.3k 0.9×	473 0.6×	751 1.0×	219 0.3×	82	5.4k
Jianghong Zhang China	29	2.5k 0.7×	841 0.6×	487 0.6×	652 0.9×	382 0.6×	84	3.9k

Countries citing papers authored by Ryoko Okamoto

Since Specialization

Citations

This map shows the geographic impact of Ryoko Okamoto's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ryoko Okamoto with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ryoko Okamoto more than expected).

Fields of papers citing papers by Ryoko Okamoto

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ryoko Okamoto. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ryoko Okamoto. The network helps show where Ryoko Okamoto may publish in the future.

Co-authorship network of co-authors of Ryoko Okamoto

This figure shows the co-authorship network connecting the top 25 collaborators of Ryoko Okamoto. A scholar is included among the top collaborators of Ryoko Okamoto based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ryoko Okamoto. Ryoko Okamoto is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Jain, Akanksha, Fátima Sanchís-Calleja, Zhisong He, et al.. (2025). Morphodynamics of human early brain organoid development. Nature. 644(8078). 1010–1019. 8 indexed citations

Nikolova, Marina, Zhisong He, Makiko Seimiya, et al.. (2025). Fate and state transitions during human blood vessel organoid development. Cell. 188(12). 3329–3348.e31. 9 indexed citations

Sanchís-Calleja, Fátima, Nadezhda V. Azbukina, Akanksha Jain, et al.. (2025). Systematic scRNA-seq screens profile neural organoid response to morphogens. Nature Methods. 23(2). 465–478.

Ahn, Seungkuk, Akanksha Jain, Krishna Chaitanya Kasuba, et al.. (2024). Engineering fibronectin-templated multi-component fibrillar extracellular matrices to modulate tissue-specific cell response. Biomaterials. 308. 122560–122560. 9 indexed citations

Fleck, Jonas Simon, Sophie Jansen, Damian Wollny, et al.. (2022). Inferring and perturbing cell fate regulomes in human brain organoids. Nature. 621(7978). 365–372. 145 indexed citations breakdown →

Correia, Ana Luísa, Joao C. Guimaraes, Priska Auf der Maur, et al.. (2021). Hepatic stellate cells suppress NK cell-sustained breast cancer dormancy. Nature. 594(7864). 566–571. 208 indexed citations breakdown →

Obradović, Milan, Baptiste Hamelin, Nenad Manevski, et al.. (2019). Glucocorticoids promote breast cancer metastasis. Nature. 567(7749). 540–544. 296 indexed citations breakdown →

Madan, Vikas, Deepika Kanojia, Jia Li, et al.. (2015). Aberrant splicing of U12-type introns is the hallmark of ZRSR2 mutant myelodysplastic syndrome. Nature Communications. 6(1). 6042–6042. 173 indexed citations

Okamoto, Ryoko, Sigal Gery, Adrian F. Gombart, et al.. (2014). Deficiency of CCAAT/Enhancer Binding Protein-Epsilon Reduces Atherosclerotic Lesions in LDLR−/− Mice. PLoS ONE. 9(1). e85341–e85341. 2 indexed citations

10.

Garg, Manoj, Ryoko Okamoto, Yasunobu Nagata, et al.. (2014). Establishment and Characterization of Novel Human Primary and Metastatic Anaplastic Thyroid Cancer Cell Lines and Their Genomic Evolution Over a Year as a Primagraft. The Journal of Clinical Endocrinology & Metabolism. 100(2). 725–735. 17 indexed citations

11.

Zhou, Yan, Conghui Zhao, Sigal Gery, et al.. (2013). Off-Target Effects of c-MET Inhibitors on Thyroid Cancer Cells. Molecular Cancer Therapeutics. 13(1). 134–143. 25 indexed citations

12.

Okamoto, Ryoko, Rémi Delansorne, Naoki Wakimoto, et al.. (2011). Inecalcitol, an analog of 1α,25(OH)₂D₃, induces growth arrest of androgen‐dependent prostate cancer cells. International Journal of Cancer. 130(10). 2464–2473. 43 indexed citations

13.

Akagi, Tadayuki, Nils H. Thoennissen, Gay M. Crooks, et al.. (2010). In Vivo Deficiency of Both C/EBPβ and C/EBPε Results in Highly Defective Myeloid Differentiation and Lack of Cytokine Response. PLoS ONE. 5(11). e15419–e15419. 44 indexed citations

14.

Thoennissen, Nils H., Gabriela B. Iwanski, Ngan Doan, et al.. (2009). Cucurbitacin B Induces Apoptosis by Inhibition of the JAK/STAT Pathway and Potentiates Antiproliferative Effects of Gemcitabine on Pancreatic Cancer Cells. Cancer Research. 69(14). 5876–5884. 203 indexed citations

15.

Saito, Tsuyako, Ryoko Okamoto, Talin Haritunians, et al.. (2008). Novel Gemini vitamin D3 analogs have potent antitumor activity. The Journal of Steroid Biochemistry and Molecular Biology. 112(1-3). 151–156. 26 indexed citations

16.

Sato, Tatsuhiro, Kenji Irie, Ryoko Okamoto, et al.. (2005). Common signaling pathway is used by the trans‐interaction of Necl‐5/Tage4/PVR/CD155 and nectin, and of nectin and nectin during the formation of cell–cell adhesion. Cancer Science. 96(9). 578–589. 21 indexed citations

17.

Okamoto, Ryoko, et al.. (2005). Recruitment of E‐cadherin associated with α‐ and β‐catenins and p120^ctn to the nectin‐based cell‐cell adhesion sites by the action of 12‐O‐tetradecanoylphorbol‐13‐acetate in MDCK cells. Genes to Cells. 10(5). 435–445. 25 indexed citations

18.

Irie, Kenji, et al.. (2005). Transcriptional activation of the mouse Necl-5/Tage4/PVR/CD155 gene by fibroblast growth factor or oncogenic Ras through the Raf–MEK–ERK–AP-1 pathway. Oncogene. 24(13). 2229–2235. 65 indexed citations

19.

Sato, Tatsuhiro, Naoyuki Fujita, Akio Yamada, et al.. (2005). Regulation of the Assembly and Adhesion Activity of E-cadherin by Nectin and Afadin for the Formation of Adherens Junctions in Madin-Darby Canine Kidney Cells. Journal of Biological Chemistry. 281(8). 5288–5299. 127 indexed citations

20.

Komori, Toshihisa, Hideshi Yagi, Shogo Nomura, et al.. (1997). Targeted Disruption of Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts. Cell. 89(5). 755–764. 3552 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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