Yoichi Shinkai

28.6k total citations · 8 hit papers
185 papers, 22.2k citations indexed

About

Yoichi Shinkai is a scholar working on Molecular Biology, Immunology and Genetics. According to data from OpenAlex, Yoichi Shinkai has authored 185 papers receiving a total of 22.2k indexed citations (citations by other indexed papers that have themselves been cited), including 134 papers in Molecular Biology, 34 papers in Immunology and 27 papers in Genetics. Recurrent topics in Yoichi Shinkai's work include Epigenetics and DNA Methylation (90 papers), Cancer-related gene regulation (47 papers) and Genomics and Chromatin Dynamics (44 papers). Yoichi Shinkai is often cited by papers focused on Epigenetics and DNA Methylation (90 papers), Cancer-related gene regulation (47 papers) and Genomics and Chromatin Dynamics (44 papers). Yoichi Shinkai collaborates with scholars based in Japan, United States and Canada. Yoichi Shinkai's co-authors include Makoto Tachibana, Shuichi Yamada, Sidonia Fagarasan, Tasuku Honjo, Masamichi Muramatsu, Kazuo Kinoshita, Kenji Sugimoto, Naoki Takeda, Frederick W. Alt and Mikiko Fukuda and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Yoichi Shinkai

184 papers receiving 21.8k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme

2000 2.6k citations Yoichi Shinkai et al. profile →
RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1992 2.2k citations Yoichi Shinkai profile →
G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis

2002 992 citations Makoto Tachibana, Masami Nozaki et al. Genes & Development profile →
Partitioning and Plasticity of Repressive Histone Methylation States in Mammalian Chromatin

2003 912 citations Makoto Tachibana, Yoichi Shinkai et al. profile →
Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9

2005 645 citations Makoto Tachibana, Naoki Takeda et al. Genes & Development profile →
SET Domain-containing Protein, G9a, Is a Novel Lysine-preferring Mammalian Histone Methyltransferase with Hyperactivity and Specific Selectivity to Lysines 9 and 27 of Histone H3

2001 639 citations Makoto Tachibana, Yoichi Shinkai et al. profile →
Histone Methyltransferases Direct Different Degrees of Methylation to Define Distinct Chromatin Domains

2003 637 citations Yoichi Shinkai et al. profile →
Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET

2010 587 citations Hiroki Miyashita, Hitoshi Miyachi et al. Nature profile →

Peers

Countries citing papers authored by Yoichi Shinkai

Since Specialization

Citations

This map shows the geographic impact of Yoichi Shinkai's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yoichi Shinkai with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yoichi Shinkai more than expected).

Fields of papers citing papers by Yoichi Shinkai

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yoichi Shinkai. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yoichi Shinkai. The network helps show where Yoichi Shinkai may publish in the future.

Co-authorship network of co-authors of Yoichi Shinkai

This figure shows the co-authorship network connecting the top 25 collaborators of Yoichi Shinkai. A scholar is included among the top collaborators of Yoichi Shinkai based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Yoichi Shinkai. Yoichi Shinkai is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Mitochondrial hyper-acetylation induced by an engineered acetyltransferase promotes cellular senescence 2025 ·iScience ·Tadahiro Shimazu, Ayane Kataoka, (unknown), Naoshi Dohmae, Yoichi Shinkai	1
2	Epigenetic plasticity safeguards heterochromatin configuration in mammals 2023 ·Nucleic Acids Research ·Kei Fukuda, Takeshi Shimi, (unknown), Takao Ono, Takehiro Suzuki, (unknown), (unknown), Hisashi Miura, Ichiro Hiratani, Kazuho Ikeda, Yasushi Okada, Naoshi Dohmae, Shigenobu Yonemura, Azusa Inoue, Hiroshi Kimurâ, Yoichi Shinkai	17
3	Histidine N1-position-specific methyltransferase CARNMT1 targets C3H zinc finger proteins and modulates RNA metabolism 2023 ·Genes & Development ·Tadahiro Shimazu, Rei Yoshimoto, (unknown), Takehiro Suzuki, Shogo Matoba, Michiko Hirose, Mai Akakabe, Yoshihiro Sohtome, Mikiko Sodeoka, Atsuo Ogura, Naoshi Dohmae, Yoichi Shinkai	12
4	METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance 2022 ·eLife ·Eriko Suzuki, Tadahiro Shimazu, Mari Takahashi, (unknown), Takehiro Suzuki, Kazuhiro Kashiwagi, Yoshihiro Sohtome, Mai Akakabe, Mikiko Sodeoka, Naoshi Dohmae, Takuhiro Ito, Yoichi Shinkai, Shintaro Iwasaki	18
5	Propargylic Se-adenosyl-l-selenomethionine: A Chemical Tool for Methylome Analysis 2021 ·Accounts of Chemical Research ·Yoshihiro Sohtome, Tadahiro Shimazu, Yoichi Shinkai, Mikiko Sodeoka	26
6	Histone H3K9 Methyltransferase G9a in Oocytes Is Essential for Preimplantation Development but Dispensable for CG Methylation Protection 2019 ·Cell Reports ·Wan Kin Au Yeung, Julie Brind’Amour, (unknown), Kazuo Yamagata, Robert Feil, Matthew C. Lorincz, Makoto Tachibana, Yoichi Shinkai, Hiroyuki Sasaki	51
7	Unveiling epidithiodiketopiperazine as a non-histone arginine methyltransferase inhibitor by chemical protein methylome analyses 2018 ·Chemical Communications ·Yoshihiro Sohtome, Tadahiro Shimazu, (unknown), Shinya Fujishiro, Mai Akakabe, (unknown), Kosuke Dodo, Akihiro Ito, Minoru Yoshida, Yoichi Shinkai, Mikiko Sodeoka	9
8	Impact of nucleic acid and methylated H3K9 binding activities of Suv39h1 on its heterochromatin assembly 2017 ·eLife ·A Shirai, Takayuki Kawaguchi, (unknown), Daisuke Muramatsu, (unknown), Yoshifumi Nishimura, Hiroshi Kimurâ, Jun‐ichi Nakayama, Yoichi Shinkai	68
9	Histone methyltransferase Setdb1 regulates energy metabolism in hematopoietic stem and progenitor cells 2015 ·Experimental Hematology ·Shuhei Koide, Keiyo Takubo, Motohiko Oshima, Satoru Miyagi, Atsunori Saraya, Changshan Wang, Hirotaka Matsui, Hiroshi Kimurâ, Yoichi Shinkai, Toshio Suda, Atsushi Iwama	3
10	Epigenetic Regulation of Mouse Sex Determination by the Histone Demethylase Jmjd1a 2013 ·Science ·Shunsuke Kuroki, Shogo Matoba, Mika Akiyoshi, Yasuko Matsumura, Hitoshi Miyachi, Nathan Mise, Kuniya Abe, Atsuo Ogura, Dagmar Wilhelm, Peter Koopman, Masami Nozaki, Yoshiakira Kanai, Yoichi Shinkai, Makoto Tachibana	197
11	Distinct Roles for Histone Methyltransferases G9a and GLP in Cancer Germ-Line Antigen Gene Regulation in Human Cancer Cells and Murine Embryonic Stem Cells 2009 ·Molecular Cancer Research ·Petra A. Link, Omkaram Gangisetty, Smitha R. James, Anna Woloszynska‐Read, Makoto Tachibana, Yoichi Shinkai, Adam R. Karpf	47
12	Functional Analysis of Histone Methyltransferase G9a in B and T Lymphocytes 2008 ·The Journal of Immunology ·Lance R. Thomas, Hiroki Miyashita, (unknown), Steven Pierce, Makoto Tachibana, Elias Hobeika, Michael Reth, Yoichi Shinkai, Eugene M. Oltz	54
13	The High-Mobility-Group Box Protein SSRP1/T160 Is Essential for Cell Viability in Day 3.5 Mouse Embryos 2003 ·Molecular and Cellular Biology ·(unknown), Heather Bendall, Geoffrey G. Hicks, Abudi Nashabi, Hitoshi Sakano, Yoichi Shinkai, Marisa Gariglio, Eugene M. Oltz, H. Earl Ruley	55
14	Increase of TCR Vβ Accessibility within Eβ Regulatory Region Influences its Recombination Frequency But Not Allelic Exclusion 2003 ·The Journal of Immunology ·Makoto Senoo, Lili Wang, Daisuke Suzuki, Naoki Takeda, Yoichi Shinkai, Sonoko Habu	24
15	Production of cloned mice from embryonic stem cells arrested at metaphase 2001 ·Reproduction ·Yoshikuni Ono, Nobuyuki Shimozawa, (unknown), (unknown), K Hioki, Makoto Tachibana, Yoichi Shinkai, Mamoru Ito, Takahiro Kono	34
16	Telomere Maintenance in Telomerase-Deficient Mouse Embryonic Stem Cells: Characterization of an Amplified Telomeric DNA 2000 ·Molecular and Cellular Biology ·Hiroyuki Niida, Yoichi Shinkai, M. Prakash Hande, Takehisa Matsumoto, Shoko Takehara, Makoto Tachibana, Mitsuo Oshimura, Peter M. Lansdorp, Yasuhiro Furuichi	113
17	Expression and induction of nuclear factor-kappa B-related proteins in thymocytes. 1995 ·The Journal of Immunology ·Jyoti Misra Sen, (unknown), Yoichi Shinkai, (unknown), Frederick W. Alt, Steven J. Burakoff, Ranjan Sen	56
18	Cellular and Molecular Bases for the Immunopathology of the Myocardial Cell Damage Involved in Acute Viral Myocarditis with Special Reference to Dilated Cardiomyopathy. 1992 ·Japanese Circulation Journal ·Yoshinori Seko, Tsutomu Yamazaki, Yoichi Shinkai, Hideo Yagita∥, Ko Okumura, Shigeto Naito, K Imataka, (unknown), Y Yazaki	19
19	Thy-1 -positive dendritic epidermal cells contain a killer protein perforin 1990 ·International Immunology ·Tetsuji Kobata, Yoichi Shinkai, (unknown), Akemi Koyanagi, Hideo Yagita∥, (unknown), (unknown), Stephen I. Katz, Ko Okumura	19
20	Homology of perforin to the ninth component of complement (C9) 1988 ·Nature ·Yoichi Shinkai, Koji Takio, Ko Okumura	226

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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