Ka‐Fai To

49.7k total citations · 10 hit papers
566 papers, 34.7k citations indexed

About

Ka‐Fai To is a scholar working on Molecular Biology, Oncology and Surgery. According to data from OpenAlex, Ka‐Fai To has authored 566 papers receiving a total of 34.7k indexed citations (citations by other indexed papers that have themselves been cited), including 234 papers in Molecular Biology, 158 papers in Oncology and 124 papers in Surgery. Recurrent topics in Ka‐Fai To's work include Epigenetics and DNA Methylation (59 papers), RNA modifications and cancer (57 papers) and Cancer-related molecular mechanisms research (51 papers). Ka‐Fai To is often cited by papers focused on Epigenetics and DNA Methylation (59 papers), RNA modifications and cancer (57 papers) and Cancer-related molecular mechanisms research (51 papers). Ka‐Fai To collaborates with scholars based in Hong Kong, China and United States. Ka‐Fai To's co-authors include Joseph J.�Y. Sung, Kwok Wai Lo, Jun Yu, Wai K. Leung, Joanna H. Tong, Anthony W.H. Chan, Paul K.S. Chan, Francis K.L. Chan, Wei Kang and Paul B.S. Lai and has published in prestigious journals such as New England Journal of Medicine, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Ka‐Fai To

556 papers receiving 34.1k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A Major Outbreak of Severe Acute Respiratory Syndrome in Hong Kong

2003 1.9k citations Paul K.S. Chan, Ka‐Fai To et al. profile →
Biomarker Analyses and Final Overall Survival Results From a Phase III, Randomized, Open-Label, First-Line Study of Gefitinib Versus Carboplatin/Paclitaxel in Clinically Selected Patients With Advanced Non–Small-Cell Lung Cancer in Asia (IPASS)

2011 1.2k citations Ka‐Fai To, Tony Mok et al. profile →
MET Amplification and Exon 14 Splice Site Mutation Define Unique Molecular Subgroups of Non–Small Cell Lung Carcinoma with Poor Prognosis

2016 330 citations Joanna H. Tong, Sai F. Yeung et al. Clinical Cancer Research profile →
Macrophage-to-Myofibroblast Transition Contributes to Interstitial Fibrosis in Chronic Renal Allograft Injury

2017 323 citations Ka‐Fai To, David J. Nikolic‐Paterson et al. profile →
Nasopharyngeal carcinoma: an evolving paradigm

2021 315 citations Kwok Wai Lo, Ka‐Fai To et al. profile →
Cellular zinc metabolism and zinc signaling: from biological functions to diseases and therapeutic targets

2024 154 citations Bonan Chen, Wai Nok Chan et al. profile →
Targeting m ⁶ A reader YTHDF1 augments antitumour immunity and boosts anti-PD-1 efficacy in colorectal cancer

2023 154 citations Chi Chun Wong, Wei Kang et al. profile →
Streptococcus anginosus promotes gastric inflammation, atrophy, and tumorigenesis in mice

2024 120 citations Kaili Fu, Alvin H.K. Cheung et al. profile →
Gut microbiome dysbiosis across early Parkinson’s disease, REM sleep behavior disorder and their first-degree relatives

2023 93 citations Paul K.S. Chan, Sunny H. Wong et al. profile →
The arginine metabolism and its deprivation in cancer therapy

2025 17 citations Bonan Chen, Ka‐Fai To et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Ka‐Fai To Hong Kong	100	13.5k	8.9k	7.6k	6.2k	6.2k	566	34.7k
Francis K.L. Chan Hong Kong	106	11.6k 0.9×	5.7k 0.6×	2.5k 0.3×	6.2k 1.0×	15.8k 2.5×	628	43.6k
Nigel Mackman United States	106	12.7k 0.9×	3.8k 0.4×	5.6k 0.7×	3.6k 0.6×	3.4k 0.5×	508	39.6k
Georg Schett Germany	118	21.6k 1.6×	8.7k 1.0×	4.3k 0.6×	4.8k 0.8×	4.6k 0.7×	1.1k	59.6k
Giovanni Scambia Italy	89	11.1k 0.8×	12.4k 1.4×	4.3k 0.6×	4.2k 0.7×	11.7k 1.9×	2.0k	49.2k
Kazuaki Chayama Japan	99	7.5k 0.6×	7.4k 0.8×	3.0k 0.4×	9.8k 1.6×	10.7k 1.7×	1.4k	45.3k
Kaichun Wu China	80	11.4k 0.8×	4.1k 0.5×	5.9k 0.8×	2.6k 0.4×	3.7k 0.6×	622	21.3k
Daiming Fan China	81	13.4k 1.0×	4.5k 0.5×	7.9k 1.0×	2.6k 0.4×	4.4k 0.7×	573	24.0k
Herbert M. Pinedo Netherlands	91	12.1k 0.9×	15.8k 1.8×	3.5k 0.5×	3.9k 0.6×	3.0k 0.5×	571	29.8k
William McGuire United States	94	12.5k 0.9×	15.8k 1.8×	7.9k 1.0×	6.2k 1.0×	1.8k 0.3×	472	41.7k
Shuji Ogino United States	96	12.4k 0.9×	17.2k 1.9×	6.9k 0.9×	5.4k 0.9×	4.2k 0.7×	455	33.3k

Countries citing papers authored by Ka‐Fai To

Since Specialization

Citations

This map shows the geographic impact of Ka‐Fai To's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ka‐Fai To with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ka‐Fai To more than expected).

Fields of papers citing papers by Ka‐Fai To

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ka‐Fai To. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ka‐Fai To. The network helps show where Ka‐Fai To may publish in the future.

Co-authorship network of co-authors of Ka‐Fai To

This figure shows the co-authorship network connecting the top 25 collaborators of Ka‐Fai To. A scholar is included among the top collaborators of Ka‐Fai To based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ka‐Fai To. Ka‐Fai To is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Chan, Wai Nok, Bonan Chen, Alvin H.K. Cheung, et al.. (2022). Targeting YAP1/TAZ in nonsmall‐cell lung carcinoma: From molecular mechanisms to precision medicine. International Journal of Cancer. 152(4). 558–571. 12 indexed citations

Liu, Xiaoli, Yifei Wang, Bonan Chen, et al.. (2022). Targeting the Hippo Pathway in Gastric Cancer and Other Malignancies in the Digestive System: From Bench to Bedside. Biomedicines. 10(10). 2512–2512. 18 indexed citations

Zhao, Liuyang, Xiang Zhang, Yunfei Zhou, et al.. (2022). Parvimonas micra promotes colorectal tumorigenesis and is associated with prognosis of colorectal cancer patients. Oncogene. 41(36). 4200–4210. 78 indexed citations

Choi, Paul Cheung‐Lung, et al.. (2022). PRAME immunostain expression in sebaceous lesions, cutaneous carcinomas and adnexal structures. Pathology. 54(6). 721–728. 12 indexed citations

Chung, Jeff Yat‐Fai, Max Kam‐Kwan Chan, Philip Chiu‐Tsun Tang, et al.. (2021). AANG: A natural compound formula for overcoming multidrug resistance via synergistic rebalancing the TGF‐β/Smad signalling in hepatocellular carcinoma. Journal of Cellular and Molecular Medicine. 25(20). 9805–9813. 16 indexed citations

Chung, Jeff Yat‐Fai, Max Kam‐Kwan Chan, Alex Siu Wing Chan, et al.. (2021). TGF-β Signaling: From Tissue Fibrosis to Tumor Microenvironment. International Journal of Molecular Sciences. 22(14). 7575–7575. 125 indexed citations

Xue, Vivian Weiwen, Jeff Yat‐Fai Chung, Philip Chiu‐Tsun Tang, et al.. (2021). USMB-shMincle: a virus-free gene therapy for blocking M1/M2 polarization of tumor-associated macrophages. Molecular Therapy — Oncolytics. 23. 26–37. 23 indexed citations

Wong, Chi Hin, Youjia Li, Stephen L. Chan, et al.. (2020). CircFOXK2 Promotes Growth and Metastasis of Pancreatic Ductal Adenocarcinoma by Complexing with RNA-Binding Proteins and Sponging MiR-942. Cancer Research. 80(11). 2138–2149. 117 indexed citations

Tang, Patrick Ming‐Kuen, Yingying Zhang, Jun Xiao, et al.. (2020). Neural transcription factor Pou4f1 promotes renal fibrosis via macrophage–myofibroblast transition. Proceedings of the National Academy of Sciences. 117(34). 20741–20752. 120 indexed citations

10.

Li, Chunjie, Vivian Weiwen Xue, Qingming Wang, et al.. (2020). The Mincle/Syk/NF-κB Signaling Circuit Is Essential for Maintaining the Protumoral Activities of Tumor-Associated Macrophages. Cancer Immunology Research. 8(8). 1004–1017. 59 indexed citations

11.

Zhang, Jinglin, Yuhang Zhou, Tingting Huang, et al.. (2018). FGF18, a prominent player in FGF signaling, promotes gastric tumorigenesis through autocrine manner and is negatively regulated by miR-590-5p. Oncogene. 38(1). 33–46. 43 indexed citations

12.

Tong, Joanna H., Sai F. Yeung, Anthony W.H. Chan, et al.. (2016). MET Amplification and Exon 14 Splice Site Mutation Define Unique Molecular Subgroups of Non–Small Cell Lung Carcinoma with Poor Prognosis. Clinical Cancer Research. 22(12). 3048–3056. 330 indexed citations breakdown →

13.

Tian, Yuan, Vincent Wai‐Sun Wong, Grace Lai–Hung Wong, et al.. (2015). Histone Deacetylase HDAC8 Promotes Insulin Resistance and β-Catenin Activation in NAFLD-Associated Hepatocellular Carcinoma. Cancer Research. 75(22). 4803–4816. 110 indexed citations

14.

Kang, Wei, Joanna H. Tong, Anthony W.H. Chan, et al.. (2011). Yes-Associated Protein 1 Exhibits Oncogenic Property in Gastric Cancer and Its Nuclear Accumulation Associates with Poor Prognosis. Clinical Cancer Research. 17(8). 2130–2139. 211 indexed citations

15.

Cheng, Alfred S.L., Suki S. Lau, Yangchao Chen, et al.. (2011). EZH2-Mediated Concordant Repression of Wnt Antagonists Promotes β-Catenin–Dependent Hepatocarcinogenesis. Cancer Research. 71(11). 4028–4039. 180 indexed citations

16.

Ching, Arthur K., Anthony W.H. Chan, Kwong Wai Choy, et al.. (2010). MiR-222 Overexpression Confers Cell Migratory Advantages in Hepatocellular Carcinoma through Enhancing AKT Signaling. Clinical Cancer Research. 16(3). 867–875. 210 indexed citations

17.

Siu, Kam‐Leung, Kin‐Hang Kok, Raymond Wai Ming Lung, et al.. (2008). An Epstein-Barr virus–encoded microRNA targets PUMA to promote host cell survival. The Journal of Experimental Medicine. 205(11). 2551–2560. 369 indexed citations

18.

Chow, Chit, Nathalie Wong, Ka‐Fai To, & Kwok Wai Lo. (2007). Activin beta E (INHBE), a RASSF1A target gene is downregulated in hepatocellular carcinoma. Cancer Research. 67. 3662–3662. 3 indexed citations

19.

Maren, Wendy W. C. van, Francis K.L. Chan, Wai‐Sum Chan, et al.. (2006). Extremely Low Exposure of a Community to Severe Acute Respiratory Syndrome Coronavirus: False Seropositivity due to Use of Bacterially Derived Antigens. Journal of Virology. 80(18). 8920–8928. 12 indexed citations

20.

Chan, Michael W.Y., et al.. (2004). siRNA silencing of TFF3 modulates angiogenesis, invasion and proliferation properties of gastric cancer cell line MKN45. Cancer Research. 64. 332–333. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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