Justin D. Lutz

1.2k citations

21 papers · 838 indexed · h-index 16

Pharmacology top 1%
- Pharmacogenetics and Drug Metabolism 12
Biochemistry top 10%
Infectious Diseases top 10%
- COVID-19 Clinical Research Studies 2
Oncology
- Drug Transport and Resistance Mechanisms 6
Pediatrics, Perinatology and Child Health top 10%
- Pharmacological Effects and Toxicity Studies 4
Computational Theory and Mathematics
- Computational Drug Discovery Methods 4
Spectroscopy
- Analytical Chemistry and Chromatography 3
Molecular Biology
- Metabolomics and Mass Spectrometry Studies 2
Clinical Biochemistry
- Metabolism and Genetic Disorders 2

Co-authors: Nina Isoherranen Anita Mathias Wendel L. Nelson Brian J. Kirby John Ling Alex Zelter Yoshiyuki Shirasaka Connie L. Davis
Cited by: Pharmacology Biochemistry Infectious Diseases
Journals: Biochemical Pharmacology (2 papers)Clinical Pharmacology & Therapeutics (5 papers)Biochimica et Biophysica Acta (BBA) - General Subjects (1 paper)
Partner nations: United States United Kingdom Germany

In The Last Decade

Justin D. Lutz

21 papers receiving 818 citations

Peers

Countries citing papers authored by Justin D. Lutz

Since Specialization

Citations

This map shows the geographic impact of Justin D. Lutz's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Justin D. Lutz with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Justin D. Lutz more than expected).

Fields of papers citing papers by Justin D. Lutz

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Justin D. Lutz. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Justin D. Lutz. The network helps show where Justin D. Lutz may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Justin D. Lutz, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Justin D. Lutz Line = papers co-authored together Justin D. Lutz links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Effect of Hepatic Impairment or Renal Impairment on the Pharmacokinetics of Aficamten Clinical Pharmacokinetics ·Donghong Xu,Justin D. Lutz,Punag Divanji,Jianlin Li,Youcef Benattia,Adrienne Griffith,Stephen B. Heitner,Stuart Kupfer,Polina German	2025	2
2	Pharmacokinetic, Pharmacodynamic, and Drug-Interaction Profile of Remdesivir, a SARS-CoV-2 Replication Inhibitor Clinical Pharmacokinetics ·Rita Humeniuk,Anita Mathias,Brian J. Kirby,Justin D. Lutz,Huyen Cao,Anu Osinusi,Darius Babusis,Danielle Porter,Xuelian Wei,John Ling,Y. Sunila Reddy,Polina German	2021	93
3	Intestinal P‐gp and Putative Hepatic OATP1B Induction: International Transporter Consortium Perspective on Drug Development Implications Clinical Pharmacology & Therapeutics ·Maciej J. Zamek‐Gliszczynski,Mitesh Patel,Xinning Yang,Justin D. Lutz,Xiaoyan Chu,Kim L. R. Brouwer,Yurong Lai,Caroline A. Lee,Sibylle Neuhoff,Mary F. Paine,Yuichi Sugiyama,Kunal S. Taskar,Aleksandra Galetin	2020	39
4	Biochemical characterization of tirabrutinib and other irreversible inhibitors of Bruton's tyrosine kinase reveals differences in on - and off - target inhibition Biochimica et Biophysica Acta (BBA) - General Subjects ·Albert Liclican,Loredana Serafini,Weimei Xing,Gregg Czerwieniec,Bart Steiner,Ting Wang,Katherine M. Brendza,Justin D. Lutz,Kathleen S. Keegan,Adrian S. Ray,Brian E. Schultz,Roman Sakowicz,Joy Y. Feng	2020	74
5	Organic Anion Transporting Polypeptide Inhibition Dramatically Increases Plasma Exposure but not Pharmacodynamic Effect nor Inferred Hepatic Intracellular Exposure of Firsocostat Clinical Pharmacology & Therapeutics ·Brian J. Kirby,Justin D. Lutz,Mun Sang Yue,Kimberly L. Garrison,Ann Qin,Lorraine Ampaw,Carine Beysen,Robert P. Myers,Brian P. Kearney,Anita Mathias	2020	10
6	Safety, Pharmacokinetics and Pharmacodynamics of Selgantolimod, an Oral Toll-Like Receptor 8 Agonist: A Phase Ia Study in Healthy Subjects Antiviral Therapy ·Maribel Reyes,Justin D. Lutz,Audrey Lau,Anuj Gaggar,Ethan Grant,Adarsh Joshi,Richard L. Mackman,John Ling,Susanna K. Tan,Natarajan Ayithan,Stéphane Daffis,Jacky Woo,Peiwen Wu,Tina I. Lam,Simon P. Fletcher,Shyamasundaran Kottilil,Bhawna Poonia,Edward Gane,Anita Mathias,Polina German	2019	12
7	Cytochrome P450 3A Induction Predicts P‐glycoprotein Induction; Part 2: Prediction of Decreased Substrate Exposure After Rifabutin or Carbamazepine Clinical Pharmacology & Therapeutics ·Justin D. Lutz,Brian J. Kirby,Lu Wang,Qinghua Song,John Ling,Benedetta Massetto,Angela Worth,Brian P. Kearney,Anita Mathias	2018	60
8	Cytochrome P450 3A Induction Predicts P‐glycoprotein Induction; Part 1: Establishing Induction Relationships Using Ascending Dose Rifampin Clinical Pharmacology & Therapeutics ·Justin D. Lutz,Brian J. Kirby,Lu Wang,Qinghua Song,John Ling,Benedetta Massetto,Angela Worth,Brian P. Kearney,Anita Mathias	2018	63
9	Use of a cocktail probe to assess potential drug interactions with cytochrome P450 after administration of belatacept, a costimulatory immunomodulator British Journal of Clinical Pharmacology ·Daphne Williams,Xiaolu Tao,Li Zhu,M. Stonier,Justin D. Lutz,Eric Masson,Sean X. Zhang,Bishu Ganguly,Zoe Tzogas,Susan Lubin,Bindu Murthy	2016	13
10	Detection of an Endogenous Urinary Biomarker Associated With Cyp2D6 Activity Using Global Metabolomics Pharmacogenomics ·Jessica Tay-Sontheimer,Laura M. Shireman,Richard P. Beyer,Taurence Senn,Daniela Witten,Robin E. Pearce,Andrea Gaedigk,Cletus L Gana Fomban,Justin D. Lutz,Nina Isoherranen,Kenneth E. Thummel,Oliver Fiehn,J. Steven Leeder,Yvonne S. Lin	2014	36
11	Stereoselective Inhibition of CYP2C19 and CYP3A4 by Fluoxetine and Its Metabolite: Implications for Risk Assessment of Multiple Time-Dependent Inhibitor Systems Drug Metabolism and Disposition ·Justin D. Lutz,Brooke M. VandenBrink,K. Naveen Babu,Wendel L. Nelson,Kent L. Kunze,Nina Isoherranen	2013	22
12	Inhibition of CYP2C19 and CYP3A4 by Omeprazole Metabolites and Their Contribution to Drug-Drug Interactions Drug Metabolism and Disposition ·Yoshiyuki Shirasaka,Jennifer E. Sager,Justin D. Lutz,Connie L. Davis,Nina Isoherranen	2013	87
13	Special Section on Prediction of Human Pharmacokinetic Parameters from In Vitro Systems Stereoselective Inhibition of CYP2C19 and CYP3A4 by Fluoxetine and Its Metabolite: Implications for Risk Assessment of Multiple Time- Dependent Inhibitor Systems s Justin D. Lutz,Brooke M. VandenBrink,K. Naveen Babu,Wendel L. Nelson,Kent L. Kunze,Nina Isoherranen	2013	1
14	In vitro-to-in vivopredictions of drug–drug interactions involving multiple reversible inhibitors Expert Opinion on Drug Metabolism & Toxicology ·Justin D. Lutz,Nina Isoherranen	2012	17
15	Importance of Multi-P450 Inhibition in Drug–Drug Interactions: Evaluation of Incidence, Inhibition Magnitude, and Prediction from in Vitro Data Chemical Research in Toxicology ·Nina Isoherranen,Justin D. Lutz,Sophie P. Chung,Houda Hachad,René H. Levy,Isabelle Ragueneau‐Majlessi	2012	31
16	Comparison of the function and expression of CYP26A1 and CYP26B1, the two retinoic acid hydroxylases Biochemical Pharmacology ·Ariel R. Topletz,Jayne E. Thatcher,Alex Zelter,Justin D. Lutz,Suzanne Tay,Wendel L. Nelson,Nina Isoherranen	2011	77
17	Prediction of Relative In Vivo Metabolite Exposure from In Vitro Data Using Two Model Drugs: Dextromethorphan and Omeprazole Drug Metabolism and Disposition ·Justin D. Lutz,Nina Isoherranen	2011	45
18	Stereospecific Metabolism of Itraconazole by CYP3A4: Dioxolane Ring Scission of Azole Antifungals Drug Metabolism and Disposition ·Chi-Chi Peng,Wei Shi,Justin D. Lutz,Kent L. Kunze,Jun O. Liu,Wendel L. Nelson,Nina Isoherranen	2011	23
19	Rationalization and prediction ofin vivometabolite exposures: the role of metabolite kinetics, clearance predictions andin vitroparameters Expert Opinion on Drug Metabolism & Toxicology ·Justin D. Lutz,Yasushi Fujioka,Nina Isoherranen	2010	29
20	Expression and functional characterization of cytochrome P450 26A1, a retinoic acid hydroxylase Biochemical Pharmacology ·Justin D. Lutz,Vaishali Dixit,Catherine K. Yeung,Leslie J. Dickmann,Alex Zelter,Jayne E. Thatcher,Wendel L. Nelson,Nina Isoherranen	2008	76

About Justin D. Lutz

Justin D. Lutz is a scholar working on Pharmacology, Clinical Biochemistry and Pediatrics, Perinatology and Child Health, having authored 21 papers that have together received 838 indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (12 papers), Drug Transport and Resistance Mechanisms (6 papers), Computational Drug Discovery Methods (4 papers), Pharmacological Effects and Toxicity Studies (4 papers), Analytical Chemistry and Chromatography (3 papers), Metabolomics and Mass Spectrometry Studies (2 papers), Metabolism and Genetic Disorders (2 papers) and COVID-19 Clinical Research Studies (2 papers). The work is most often cited by research in Pharmacology (294 citations), Biochemistry (51 citations) and Infectious Diseases (154 citations). Justin D. Lutz has collaborated with scholars based in United States, United Kingdom and Germany. Frequent co-authors include Nina Isoherranen, Anita Mathias, Wendel L. Nelson, Brian J. Kirby, John Ling, Alex Zelter, Yoshiyuki Shirasaka, Connie L. Davis, Jennifer E. Sager and Brian P. Kearney. Their work appears in journals such as Biochemical Pharmacology, Clinical Pharmacology & Therapeutics and Biochimica et Biophysica Acta (BBA) - General Subjects.

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