Andrew C. Chan

20.6k total citations · 5 hit papers
113 papers, 16.2k citations indexed

About

Andrew C. Chan is a scholar working on Immunology, Molecular Biology and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, Andrew C. Chan has authored 113 papers receiving a total of 16.2k indexed citations (citations by other indexed papers that have themselves been cited), including 85 papers in Immunology, 30 papers in Molecular Biology and 29 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in Andrew C. Chan's work include T-cell and B-cell Immunology (60 papers), Immune Cell Function and Interaction (35 papers) and Monoclonal and Polyclonal Antibodies Research (27 papers). Andrew C. Chan is often cited by papers focused on T-cell and B-cell Immunology (60 papers), Immune Cell Function and Interaction (35 papers) and Monoclonal and Polyclonal Antibodies Research (27 papers). Andrew C. Chan collaborates with scholars based in United States, Germany and France. Andrew C. Chan's co-authors include Arthur Weiss, Makio Iwashima, Paul J. Carter, Bryan Irving, Flavius Martin, Andréy S. Shaw, Christoph W. Turck, Tomohiro Kurosaki, Chong Fu and Michael L. Dustin and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Andrew C. Chan

110 papers receiving 15.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Recognition of Unique Carboxyl-Terminal Motifs by Distinct PDZ Domains

1997 1.2k citations Andrew C. Chan et al. Science profile →
ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR ζ chain

1992 902 citations Andrew C. Chan, Arthur Weiss et al. Cell profile →
Therapeutic antibodies for autoimmunity and inflammation

2010 664 citations Andrew C. Chan, Paul J. Carter Nature reviews. Immunology profile →
Sequential Interactions of the TCR with Two Distinct Cytoplasmic Tyrosine Kinases

1994 623 citations Andrew C. Chan, Arthur Weiss et al. Science profile →
T Cell Receptor Signaling Precedes Immunological Synapse Formation

2002 558 citations Andrew C. Chan, Andréy S. Shaw et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Andrew C. Chan United States	54	10.2k	6.4k	2.7k	2.5k	1.2k	113	16.2k
Michael Reth Germany	73	10.9k 1.1×	7.5k 1.2×	1.8k 0.7×	4.1k 1.6×	1.0k 0.8×	219	18.1k
André Veillette Canada	67	9.9k 1.0×	5.7k 0.9×	3.5k 1.3×	1.8k 0.7×	1.3k 1.1×	182	14.7k
Joseph B. Bolen United States	71	7.8k 0.8×	6.8k 1.1×	4.1k 1.5×	2.7k 1.1×	2.0k 1.6×	171	16.0k
Jannie Borst Netherlands	76	10.9k 1.1×	6.0k 0.9×	4.6k 1.7×	1.8k 0.7×	883 0.7×	232	18.2k
Steven J. Burakoff United States	71	9.7k 0.9×	7.7k 1.2×	3.5k 1.3×	2.4k 0.9×	1.6k 1.3×	278	17.3k
John C. Cambier United States	81	14.8k 1.5×	6.7k 1.1×	2.2k 0.8×	4.4k 1.8×	1.6k 1.3×	312	20.4k
Roger M. Perlmutter United States	62	7.5k 0.7×	5.9k 0.9×	3.4k 1.3×	2.3k 0.9×	1.0k 0.9×	125	13.2k
Andréy S. Shaw United States	79	10.3k 1.0×	11.3k 1.8×	3.6k 1.3×	2.0k 0.8×	1.8k 1.5×	192	24.3k
Gary A. Koretzky United States	74	13.0k 1.3×	8.4k 1.3×	3.8k 1.4×	1.2k 0.5×	2.4k 2.0×	208	20.7k
Doreen A. Cantrell United Kingdom	81	12.6k 1.2×	10.0k 1.6×	5.1k 1.9×	1.3k 0.5×	1.3k 1.0×	217	21.7k

Countries citing papers authored by Andrew C. Chan

Since Specialization

Citations

This map shows the geographic impact of Andrew C. Chan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Andrew C. Chan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Andrew C. Chan more than expected).

Fields of papers citing papers by Andrew C. Chan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Andrew C. Chan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Andrew C. Chan. The network helps show where Andrew C. Chan may publish in the future.

Co-authorship network of co-authors of Andrew C. Chan

This figure shows the co-authorship network connecting the top 25 collaborators of Andrew C. Chan. A scholar is included among the top collaborators of Andrew C. Chan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Andrew C. Chan. Andrew C. Chan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Chan, Andrew C., et al.. (2025). Fifty years of monoclonals: the past, present and future of antibody therapeutics. Nature reviews. Immunology. 25(10). 745–765. 5 indexed citations

Chan, Andrew C., et al.. (2025). Publisher Correction: Fifty years of monoclonals: the past, present and future of antibody therapeutics. Nature reviews. Immunology.

Han, Yuyuan, Yan Huang, L. Rasmussen, et al.. (2025). Maternal PRDM10 activates essential genes for oocyte-to-embryo transition. Nature Communications. 16(1). 1939–1939. 1 indexed citations

Hartwig, Tanja Schlaikjær, Louise Ambye, Jennifer R. Gruhn, et al.. (2023). Cell-Free Fetal DNA for Genetic Evaluation in Copenhagen Pregnancy Loss Study (COPL): A Prospective Cohort Study. Obstetrical & Gynecological Survey. 78(6). 345–346.

Spalinger, Marianne R., Thomas Schmidt, Marlene Schwarzfischer, et al.. (2019). Protein tyrosine phosphatase non-receptor type 22 modulates colitis in a microbiota-dependent manner. Journal of Clinical Investigation. 129(6). 2527–2541. 18 indexed citations

Holmes, Derek A, et al.. (2014). Dusp5 negatively regulates IL ‐33‐mediated eosinophil survival and function. The EMBO Journal. 34(2). 218–235. 48 indexed citations

Bodogai, Monica, Catalina Lee-Chang, Katarzyna Wejksza, et al.. (2013). Anti-CD20 Antibody Promotes Cancer Escape via Enrichment of Tumor-Evoked Regulatory B Cells Expressing Low Levels of CD20 and CD137L. Cancer Research. 73(7). 2127–2138. 112 indexed citations

Fiorillo, Edoardo, Valeria Orrù, Stephanie M. Stanford, et al.. (2010). Autoimmune-associated PTPN22 R620W Variation Reduces Phosphorylation of Lymphoid Phosphatase on an Inhibitory Tyrosine Residue. Journal of Biological Chemistry. 285(34). 26506–26518. 75 indexed citations

Townsend, Michael J., John G. Monroe, & Andrew C. Chan. (2010). B‐cell targeted therapies in human autoimmune diseases: an updated perspective. Immunological Reviews. 237(1). 264–283. 173 indexed citations

10.

Chan, Andrew C., Rhona H. Borts, & Eva R. Hoffmann. (2009). Temperature-Dependent Modulation of Chromosome Segregation in msh4 Mutants of Budding Yeast. PLoS ONE. 4(10). e7284–e7284. 14 indexed citations

11.

Zikherman, Julie, Michelle L. Hermiston, David Steiner, et al.. (2009). PTPN22 Deficiency Cooperates with the CD45 E613R Allele to Break Tolerance on a Non-Autoimmune Background. The Journal of Immunology. 182(7). 4093–4106. 106 indexed citations

12.

Sidhu, Sachdev S., et al.. (2008). Regulation of a Late Phase of T Cell Polarity and Effector Functions by Crtam. Cell. 132(5). 846–859. 103 indexed citations

13.

Föger, Niko, Linda Rangell, Dimitry M. Danilenko, & Andrew C. Chan. (2006). Requirement for Coronin 1 in T Lymphocyte Trafficking and Cellular Homeostasis. Science. 313(5788). 839–842. 212 indexed citations

14.

Gong, Qian, Qinglin Ou, Shiming Ye, et al.. (2005). Importance of Cellular Microenvironment and Circulatory Dynamics in B Cell Immunotherapy. The Journal of Immunology. 174(2). 817–826. 423 indexed citations

15.

Hasegawa, Kiminori, et al.. (2004). PEST Domain-Enriched Tyrosine Phosphatase (PEP) Regulation of Effector/Memory T Cells. Science. 303(5658). 685–689. 302 indexed citations

16.

Benschop, Robert J., et al.. (2001). Unique Signaling Properties of B Cell Antigen Receptor in Mature and Immature B Cells: Implications for Tolerance and Activation. The Journal of Immunology. 167(8). 4172–4179. 76 indexed citations

17.

Mora, Ana L., et al.. (2001). Inefficient ZAP-70 Phosphorylation and Decreased Thymic Selection In Vivo Result from Inhibition of NF-κB/Rel. The Journal of Immunology. 167(10). 5628–5635. 26 indexed citations

18.

Wang, Guixian, M. Kathryn Liszewski, Andrew C. Chan, & John P. Atkinson. (2000). Membrane Cofactor Protein (MCP; CD46): Isoform-Specific Tyrosine Phosphorylation. The Journal of Immunology. 164(4). 1839–1846. 87 indexed citations

19.

Zhu, Yuexin, et al.. (1995). Binding of ZAP-70 to Phosphorylated T-Cell Receptor ζ and η Enhances Its Autophosphorylation and Generates Specific Binding Sites for SH2 Domain-Containing Proteins. Molecular and Cellular Biology. 15(6). 3171–3178. 128 indexed citations

20.

Chan, Andrew C. & John P. Atkinson. (1985). Oligosaccharide structure of human C4.. The Journal of Immunology. 134(3). 1790–1798. 25 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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