Napoleone Ferrara

126.3k total citations · 58 hit papers
259 papers, 99.3k citations indexed

About

Napoleone Ferrara is a scholar working on Molecular Biology, Cancer Research and Oncology. According to data from OpenAlex, Napoleone Ferrara has authored 259 papers receiving a total of 99.3k indexed citations (citations by other indexed papers that have themselves been cited), including 222 papers in Molecular Biology, 94 papers in Cancer Research and 43 papers in Oncology. Recurrent topics in Napoleone Ferrara's work include Angiogenesis and VEGF in Cancer (192 papers), Cancer, Hypoxia, and Metabolism (76 papers) and Cell Adhesion Molecules Research (30 papers). Napoleone Ferrara is often cited by papers focused on Angiogenesis and VEGF in Cancer (192 papers), Cancer, Hypoxia, and Metabolism (76 papers) and Cell Adhesion Molecules Research (30 papers). Napoleone Ferrara collaborates with scholars based in United States, France and Canada. Napoleone Ferrara's co-authors include Hans‐Peter Gerber, Jennifer LeCouter, Terri Davis-Smyth, David W. M. Leung, Keith A. Houck, Jane Winer, Robert S. Kerbel, George Cachianes, Kenneth J. Hillan and William J. Henzel and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Napoleone Ferrara

259 papers receiving 96.0k citations

Hit Papers

The biology of VEGF and its receptors 1987 2026 2000 2013 2003 1989 1997 1994 1993 2.5k 5.0k 7.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. The biology of VEGF and its receptors
    2003 7.6k citations Napoleone Ferrara, Hans‐Peter Gerber et al. profile →
  2. Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen
    1989 4.1k citations Napoleone Ferrara et al. profile →
  3. The Biology of Vascular Endothelial Growth Factor
    1997 3.7k citations Napoleone Ferrara et al. profile →
  4. Vascular Endothelial Growth Factor in Ocular Fluid of Patients with Diabetic Retinopathy and Other Retinal Disorders
    1994 3.0k citations Napoleone Ferrara et al. profile →
  5. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
    1993 3.0k citations Jane Winer, Napoleone Ferrara et al. profile →
  6. Vascular Endothelial Growth Factor: Basic Science and Clinical Progress
    2004 2.9k citations Napoleone Ferrara profile →
  7. Angiogenesis as a therapeutic target
    2005 2.1k citations Napoleone Ferrara et al. profile →
  8. Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
    2004 2.0k citations Napoleone Ferrara, Kenneth J. Hillan et al. Nature Reviews Drug Discovery profile →
  9. VEGF in Signaling and Disease: Beyond Discovery and Development
    2019 1.9k citations Napoleone Ferrara et al. Cell profile →
  10. Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells
    1989 1.8k citations Napoleone Ferrara et al. profile →
  11. The fms -Like Tyrosine Kinase, a Receptor for Vascular Endothelial Growth Factor
    1992 1.7k citations Napoleone Ferrara et al. profile →
  12. Vascular Endothelial Growth Factor Regulates Endothelial Cell Survival through the Phosphatidylinositol 3′-Kinase/Akt Signal Transduction Pathway
    1998 1.7k citations Hans-Peter Gerber, Napoleone Ferrara et al. Journal of Biological Chemistry profile →
  13. HIF-1α Is Essential for Myeloid Cell-Mediated Inflammation
    2003 1.6k citations Hans-Peter Gerber, Napoleone Ferrara et al. Cell profile →
  14. Molecular and Biological Properties of the Vascular Endothelial Growth Factor Family of Proteins
    1992 1.4k citations Napoleone Ferrara et al. profile →
  15. Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders.
    1997 1.3k citations Napoleone Ferrara et al. profile →
  16. VEGF and the quest for tumour angiogenesis factors
    2002 1.2k citations Napoleone Ferrara profile →
  17. Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover
    2002 1.1k citations Stuart Bunting, Franklin Peale et al. profile →
  18. The Vascular Endothelial Growth Factor Family: Identification of a Fourth Molecular Species and Characterization of Alternative Splicing of RNA
    1991 1.1k citations Napoleone Ferrara, Jane Winer et al. profile →
  19. Structural Characterization and Biological Functions of Fibroblast Growth Factor
    1987 1.1k citations Napoleone Ferrara et al. profile →
  20. Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins.
    1995 1.0k citations Napoleone Ferrara et al. profile →
  21. Molecular and biological properties of vascular endothelial growth factor
    1999 987 citations Napoleone Ferrara profile →
  22. The Biology of Vascular Endothelial Growth Factor
    1997 923 citations Napoleone Ferrara profile →
  23. Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms.
    1992 916 citations Jane Winer, Napoleone Ferrara et al. Journal of Biological Chemistry profile →
  24. The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF.
    1993 904 citations Napoleone Ferrara et al. profile →
  25. Role of vascular endothelial growth factor in regulation of physiological angiogenesis
    2001 883 citations Napoleone Ferrara profile →
  26. Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR.
    1994 869 citations Jane Winer, Napoleone Ferrara et al. Journal of Biological Chemistry profile →
  27. Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model.
    1994 859 citations S Takeshita, Long Zheng et al. Journal of Clinical Investigation profile →
  28. Clinical applications of angiogenic growth factors and their inhibitors
    1999 834 citations Napoleone Ferrara et al. profile →
  29. Autocrine VEGF Signaling Is Required for Vascular Homeostasis
    2007 808 citations Napoleone Ferrara, András Nagy et al. Cell profile →
  30. Vascular Endothelial Growth Factor Induces Expression of the Antiapoptotic Proteins Bcl-2 and A1 in Vascular Endothelial Cells
    1998 782 citations Hans‐Peter Gerber, Napoleone Ferrara et al. Journal of Biological Chemistry profile →
  31. Bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody for cancer therapy
    2005 763 citations Napoleone Ferrara, Kenneth J. Hillan et al. profile →
  32. Ten years of anti-vascular endothelial growth factor therapy
    2016 759 citations Napoleone Ferrara et al. Nature Reviews Drug Discovery profile →
  33. VEGF is required for growth and survival in neonatal mice
    1999 727 citations Hans‐Peter Gerber, Kenneth J. Hillan et al. Development profile →
  34. Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro
    1992 710 citations Napoleone Ferrara et al. profile →
  35. Vascular Endothelial Growth Factor
    2009 688 citations Napoleone Ferrara profile →
  36. Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells
    2007 673 citations Farbod Shojaei, Xiumin Wu et al. profile →
  37. DEVELOPMENT OF RANIBIZUMAB, AN ANTI–VASCULAR ENDOTHELIAL GROWTH FACTOR ANTIGEN BINDING FRAGMENT, AS THERAPY FOR NEOVASCULAR AGE-RELATED MACULAR DEGENERATION
    2006 656 citations Napoleone Ferrara et al. profile →
  38. Differential Transcriptional Regulation of the Two Vascular Endothelial Growth Factor Receptor Genes
    1997 642 citations Hans‐Peter Gerber, Napoleone Ferrara et al. Journal of Biological Chemistry profile →
  39. Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium.
    1993 636 citations Napoleone Ferrara et al. profile →
  40. Targeting the tumour vasculature: insights from physiological angiogenesis
    2010 620 citations Alicia S. Chung, Napoleone Ferrara et al. profile →
  41. Developmental and Pathological Angiogenesis
    2011 599 citations Alicia S. Chung, Napoleone Ferrara profile →
  42. Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis.
    1995 575 citations Napoleone Ferrara et al. Journal of Clinical Investigation profile →
  43. Vascular endothelial growth factor is induced in response to transforming growth factor-beta in fibroblastic and epithelial cells.
    1994 574 citations Napoleone Ferrara et al. Journal of Biological Chemistry profile →
  44. Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody
    1996 572 citations Napoleone Ferrara et al. profile →
  45. VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism
    2002 567 citations Hans‐Peter Gerber, Ajay K. Malik et al. profile →
  46. The vascular endothelial growth factor family of polypeptides
    1991 560 citations Napoleone Ferrara, Jane Winer et al. profile →
  47. Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease
    2012 552 citations Napoleone Ferrara et al. Journal of Clinical Investigation profile →
  48. Anti-Vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions.
    2000 551 citations Napoleone Ferrara et al. profile →
  49. Bv8 regulates myeloid-cell-dependent tumour angiogenesis
    2007 522 citations Farbod Shojaei, Xiumin Wu et al. profile →
  50. Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: Therapeutic implications
    2002 517 citations Napoleone Ferrara profile →
  51. Analysis of Biological Effects and Signaling Properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2)
    2001 516 citations Napoleone Ferrara et al. Journal of Biological Chemistry profile →
  52. Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells
    1991 516 citations Napoleone Ferrara et al. profile →
  53. Angiogenesis-Independent Endothelial Protection of Liver: Role of VEGFR-1
    2003 513 citations Xiao Liang, Hans‐Peter Gerber et al. profile →
  54. The Carboxyl-terminal Domain(111–165) of Vascular Endothelial Growth Factor Is Critical for Its Mitogenic Potency
    1996 507 citations Napoleone Ferrara et al. Journal of Biological Chemistry profile →
  55. Synergistic Effect of Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor on Angiogenesis In Vivo
    1995 501 citations Takayuki Asahara, Christophe Bauters et al. profile →
  56. Vascular Endothelial Growth Factor A in Intraocular Vascular Disease
    2012 320 citations Napoleone Ferrara et al. profile →
  57. Biology and therapeutic targeting of vascular endothelial growth factor A
    2023 233 citations Napoleone Ferrara et al. profile →
  58. Targeting angiogenesis in oncology, ophthalmology and beyond
    2023 173 citations Yihai Cao, Róbert Langer et al. Nature Reviews Drug Discovery profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Napoleone Ferrara United States 140 61.5k 23.9k 20.6k 10.4k 10.1k 259 99.3k
Judah Folkman United States 141 62.8k 1.0× 29.5k 1.2× 24.5k 1.2× 3.3k 0.3× 8.3k 0.8× 395 105.2k
George D. Yancopoulos United States 161 55.1k 0.9× 11.9k 0.5× 14.3k 0.7× 6.0k 0.6× 16.0k 1.6× 430 103.1k
Peter Carmeliet Belgium 151 53.1k 0.9× 27.4k 1.1× 15.0k 0.7× 2.6k 0.2× 11.7k 1.2× 729 100.0k
Kari Alitalo Finland 161 56.8k 0.9× 12.5k 0.5× 45.5k 2.2× 2.4k 0.2× 8.3k 0.8× 716 94.3k
Gregg L. Semenza United States 164 64.3k 1.0× 69.1k 2.9× 15.5k 0.8× 2.0k 0.2× 9.6k 0.9× 423 116.8k
Michael Weller Germany 126 33.2k 0.5× 17.0k 0.7× 16.5k 0.8× 1.4k 0.1× 12.2k 1.2× 1.2k 89.1k
Zena Werb United States 151 45.6k 0.7× 33.6k 1.4× 35.3k 1.7× 1.1k 0.1× 18.5k 1.8× 416 110.4k
Tyler Jacks United States 129 59.4k 1.0× 26.6k 1.1× 34.2k 1.7× 1.6k 0.2× 7.2k 0.7× 338 87.8k
Joan Massagué United States 184 95.5k 1.6× 22.6k 0.9× 47.2k 2.3× 875 0.1× 12.3k 1.2× 362 137.5k
Michael B. Sporn United States 135 44.7k 0.7× 8.6k 0.4× 12.8k 0.6× 1.2k 0.1× 8.4k 0.8× 512 73.5k

Countries citing papers authored by Napoleone Ferrara

Since Specialization
Citations

This map shows the geographic impact of Napoleone Ferrara's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Napoleone Ferrara with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Napoleone Ferrara more than expected).

Fields of papers citing papers by Napoleone Ferrara

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Napoleone Ferrara. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Napoleone Ferrara. The network helps show where Napoleone Ferrara may publish in the future.

Co-authorship network of co-authors of Napoleone Ferrara

This figure shows the co-authorship network connecting the top 25 collaborators of Napoleone Ferrara. A scholar is included among the top collaborators of Napoleone Ferrara based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Napoleone Ferrara. Napoleone Ferrara is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Marra, Kyle V., Jimmy Chen, Joseph M. Miller, et al.. (2023). Development of a Semi-automated Computer-based Tool for the Quantification of Vascular Tortuosity in the Murine Retina. SHILAP Revista de lepidopterología. 4(3). 100439–100439. 1 indexed citations
2.
Cao, Yihai, Róbert Langer, & Napoleone Ferrara. (2023). Targeting angiogenesis in oncology, ophthalmology and beyond. Nature Reviews Drug Discovery. 22(6). 476–495. 173 indexed citations breakdown →
3.
Bartáková, Alena, Geoffrey Weiner, Michael C. Oldham, et al.. (2018). Endothelial cell specific gene expression changes in Oxygen Induced Retinopathy (OIR). Investigative Ophthalmology & Visual Science. 59(9). 5470–5470. 1 indexed citations
4.
Pitulescu, Mara E., Inga Schmidt, Benedetto Daniele Giaimo, et al.. (2017). Dll4 and Notch signalling couples sprouting angiogenesis and artery formation. Nature Cell Biology. 19(8). 915–927. 286 indexed citations
5.
Moriya, Junji, Xiumin Wu, Jose Zavala‐Solorio, et al.. (2013). Platelet-derived growth factor C promotes revascularization in ischemic limbs of diabetic mice. Journal of Vascular Surgery. 59(5). 1402–1409.e4. 32 indexed citations
6.
Chung, Alicia S., Marcin Kowanetz, Xiumin Wu, et al.. (2012). Differential drug class‐specific metastatic effects following treatment with a panel of angiogenesis inhibitors. The Journal of Pathology. 227(4). 404–416. 71 indexed citations
7.
Jin, Jing, Chengjin Li, Ruijun Tian, et al.. (2012). Soluble FLT1 Binds Lipid Microdomains in Podocytes to Control Cell Morphology and Glomerular Barrier Function. Cell. 151(2). 384–399. 117 indexed citations
8.
Harrelson, Zachary, et al.. (2011). The heart endocardium is derived from vascular endothelial progenitors. Development. 138(21). 4777–4787. 86 indexed citations
9.
Ferrara, Napoleone. (2009). VEGF-A: a critical regulator of blood vessel growth. European Cytokine Network. 20(4). 158–163. 261 indexed citations
10.
Korsisaari, Nina, Jed Ross, Xiumin Wu, et al.. (2008). Blocking Vascular Endothelial Growth Factor-A Inhibits the Growth of Pituitary Adenomas and Lowers Serum Prolactin Level in a Mouse Model of Multiple Endocrine Neoplasia Type 1. Clinical Cancer Research. 14(1). 249–258. 49 indexed citations
11.
Campa, Claudio, Ian Kasman, Weilan Ye, et al.. (2008). Effects of an Anti–VEGF-A Monoclonal Antibody on Laser-Induced Choroidal Neovascularization in Mice: Optimizing Methods to Quantify Vascular Changes. Investigative Ophthalmology & Visual Science. 49(3). 1178–1178. 60 indexed citations
12.
Shojaei, Farbod, Xiumin Wu, Ajay K. Malik, et al.. (2007). Tumor refractoriness to anti-VEGF treatment mediated by CD11b+Gr1+ myeloid cells. Molecular Cancer Therapeutics. 6. 1 indexed citations
13.
Tejada, Max L., Lanlan Yu, Jianying Dong, et al.. (2006). Tumor-Driven Paracrine Platelet-Derived Growth Factor Receptor α Signaling Is a Key Determinant of Stromal Cell Recruitment in a Model of Human Lung Carcinoma. Clinical Cancer Research. 12(9). 2676–2688. 94 indexed citations
14.
Ferrara, Napoleone. (2004). The Role of VEGF in Tumor Angiogenesis. 101. 1 indexed citations
15.
Ferrara, Napoleone, Kenneth J. Hillan, Hans‐Peter Gerber, & William Novotny. (2004). Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nature Reviews Drug Discovery. 3(5). 391–400. 2007 indexed citations breakdown →
16.
Baldwin, Megan E., Xiao Huan Liang, Johanna Busch, et al.. (2004). Generation of mice carrying floxed VEGFR-1 and VEGFR-2 alleles to study the effects of postnatal gene ablation on angiogenesis and hematopoiesis. Cancer Research. 64. 596–596. 1 indexed citations
17.
Giraudo, Enrico, Luca Primo, Enrica Audero, et al.. (1998). Tumor Necrosis Factor-α Regulates Expression of Vascular Endothelial Growth Factor Receptor-2 and of Its Co-receptor Neuropilin-1 in Human Vascular Endothelial Cells. Journal of Biological Chemistry. 273(34). 22128–22135. 242 indexed citations
18.
Asahara, Takayuki, Christophe Bauters, Lu Zheng, et al.. (1995). 1012-103 Restoration of Endothelial Function in Hypercholesterolemic Rabbit by Intermittent Administration of Vascular Endothelial Growth Factor. Journal of the American College of Cardiology. 25(2). 366A–366A. 2 indexed citations
19.
Takeshita, S, Long Zheng, Edi Brogi, et al.. (1994). Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model.. Journal of Clinical Investigation. 93(2). 662–670. 859 indexed citations breakdown →
20.
Ferrara, Napoleone, et al.. (1991). Aortic Smooth Muscle Cells Express and Secrete Vascular Endothelial Growth Factor. Growth Factors. 5(2). 141–148. 132 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Judah Folkman Breakdown of academic impact, for papers by George D. Yancopoulos Breakdown of academic impact, for papers by Peter Carmeliet Breakdown of academic impact, for papers by Kari Alitalo Breakdown of academic impact, for papers by Gregg L. Semenza Breakdown of academic impact, for papers by Michael Weller Breakdown of academic impact, for papers by Zena Werb Breakdown of academic impact, for papers by Tyler Jacks Breakdown of academic impact, for papers by Joan Massagué Breakdown of academic impact, for papers by Michael B. Sporn
Rankless by CCL
2026