William R. Ewing

4.5k citations

63 papers · 3.1k indexed · h-index 28

Impact in

Organic Chemistry top 0.5%
- Catalytic C–H Functionalization Methods
- Radical Photochemical Reactions
- Synthesis and Catalytic Reactions
- Catalytic Cross-Coupling Reactions
- Sulfur-Based Synthesis Techniques
- Click Chemistry and Applications
Pharmaceutical Science top 1%

Papers in

Organic Chemistry 30
- Catalytic C–H Functionalization Methods 15
- Synthesis and Catalytic Reactions 10
Pharmaceutical Science 6
- Fluorine in Organic Chemistry 6

Co-authors: Jennifer X. Qiao Jin‐Quan Yu Madeleine M. Joullié Kap‐Sun Yeung Henry W. Pauls Paul B. Weisz Peter T. W. Cheng Steven Bloom
Journals: Journal of the American Chemical Society (10 papers)Bioorganic & Medicinal Chemistry Letters (9 papers)Journal of Medicinal Chemistry (6 papers)Angewandte Chemie International Edition (3 papers)Nature Chemistry (2 papers)
Partner nations: United States Sweden Germany

In The Last Decade

William R. Ewing

62 papers receiving 3.0k citations

Peers

Countries citing papers authored by William R. Ewing

Since Specialization

Citations

This map shows the geographic impact of William R. Ewing's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William R. Ewing with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William R. Ewing more than expected).

Fields of papers citing papers by William R. Ewing

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William R. Ewing. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William R. Ewing. The network helps show where William R. Ewing may publish in the future.

Co-authorship network

The 25 scholars most cited alongside William R. Ewing, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with William R. Ewing Line = papers co-authored together William R. Ewing links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Site-selective tyrosine bioconjugation via photoredox catalysis for native-to-bioorthogonal protein transformation Nature Chemistry ·Beryl X. Li, Daniel K. Kim, Steven Bloom, Richard Y.‐C. Huang, Jennifer X. Qiao, William R. Ewing, Daniel G. Oblinsky, Gregory D. Scholes, David W. C. MacMillan	2021	121
2	Milvexian, an orally bioavailable, small‐molecule, reversible, direct inhibitor of factor XIa: In vitro studies and in vivo evaluation in experimental thrombosis in rabbits Journal of Thrombosis and Haemostasis ·Pancras C. Wong, Earl J. Crain, Jeffrey M. Bozarth, Yiming Wu, Andrew K. Dilger, Ruth R. Wexler, William R. Ewing, David Gordon, Joseph M. Luettgen	2021	42
3	Writing Your Next Medicinal Chemistry Article: Journal Bibliometrics and Guiding Principles for Industrial Authors Journal of Medicinal Chemistry ·Richard J. D. Hatley, Panayiotis A. Procopiou, E. I. Abdulkarim, Danh Khoa Nguyen, Nicholas A. Meanwell, William R. Ewing, Simon J. F. Macdonald	2020	2
4	Site-Selective Functionalization of Methionine Residues via Photoredox Catalysis Journal of the American Chemical Society ·Abdul Gafoor, Beryl X. Li, Richard Y.‐C. Huang, Jennifer X. Qiao, William R. Ewing, David W. C. MacMillan	2020	113
5	Selective C−H Halogenation with a Highly Fluorinated Manganese Porphyrin Angewandte Chemie International Edition ·Gang Li, Andrew K. Dilger, Peter T. W. Cheng, William R. Ewing, John T. Groves	2017	82
6	Selective C−H Halogenation with a Highly Fluorinated Manganese Porphyrin Angewandte Chemie ·Gang Li, Andrew K. Dilger, Peter T. W. Cheng, William R. Ewing, John T. Groves	2017	18
7	Decarboxylative alkylation for site-selective bioconjugation of native proteins via oxidation potentials Nature Chemistry ·Steven Bloom, Chun Liu, Dominik K. Kölmel, Jennifer X. Qiao, Yong Zhang, Michael A. Poss, William R. Ewing, David W. C. MacMillan	2017	309
8	Macrocyclic inhibitors of Factor XIa: Discovery of alkyl-substituted macrocyclic amide linkers with improved potency Bioorganic & Medicinal Chemistry Letters ·James R. Corte, Wu Yang, Tianan Fang, Yufeng Wang, Vijaya Lakshmi T., Michael James Cressey, William R. Ewing, Karen A. Rossi, Joseph E. Myers, S. Sheriff, Zhen Lou, Joanna J. Zheng, Timothy W. Harper, Jeffrey M. Bozarth, Yiming Wu, Joseph M. Luettgen, Dietmar Seiffert, Mimi L. Quan, Ruth R. Wexler, Patrick Y. S. Lam	2017	12
9	Characterization of a novel and selective CB1 antagonist as a radioligand for receptor occupancy studies Bioorganic & Medicinal Chemistry Letters ·Yifan Yang, Keith J. Miller, Yeheng Zhu, Hong Yang, Yuan Tian, Natesan Murugesan, Zhengxiang Gu, Maria Elisa Favarin, Ma Aránzazu Sánchez García, Kenneth W. Rohrbach, Alan Hargens, Kamelia Behnia, Mary Ann Pelleymounter, Kenneth E. Carlson, William R. Ewing	2011	2
10	Cannabinoid CB1 receptor ligand binding and function examined through mutagenesis studies of F200 and S383 European Journal of Pharmacology ·Doree Sitkoff, Ning Lee, Bruce A. Ellsworth, Qi Huang, Ellien Ajatri Lintas Toety, Mebrahtom Woldelibanos Beraki, Yanting Huang, Chong‐Qing Sun, Annapurna Pendri, Mary F. Malley, Raymond P. Scaringe, Jack Z. Gougoutas, Patricia H. Reggio, William R. Ewing, Mary Ann Pelleymounter, Kenneth E. Carlson	2010	8
11	Identification of potent 11mer Glucagon-Like Peptide-1 Receptor agonist peptides with novel C-terminal amino acids: Homohomophenylalanine analogs Peptides ·Tasir S. Haque, Ving G. Lee, M.I. Pysmennyi, Ming Lei, X. Li, Xin Li, Song‐Ping Han, Claudio Mapelli, Christopher B. Cooper, Ge Zhang, William R. Ewing, John Krupinski	2010	14
12	(d)-2-tert-Butoxycarbonylamino-5,5-difluoro-5-phenyl-pentanoic acid: Synthesis and incorporation into the growth hormone secretagogues Bioorganic & Medicinal Chemistry Letters ·Jun Li, Stephanie Chen, Brian J. Murphy, Neil Flynn, Ramakrishna Seethala, G. J. Vendura, Mujing Yan, Paul G. Sleph, A Walczynska, W. Griffith Humphreys, William R. Ewing, Jeffrey A. Robl, David Gordon, Joseph A. Tino	2008	11
13	Design and SAR of selective T-type calcium channel antagonists containing a biaryl sulfonamide core Bioorganic & Medicinal Chemistry Letters ·Jon J. Hangeland, Daniel L. Cheney, Nancy Wescott, Maulina Kartika, Paul Lévesque, Adam Rich, Lucy Sun, 笑盈, Leonard P. Adam, Diane E. Normandin, Natesan Murugesan, William R. Ewing	2007	11
14	Discovery of pyrazine carboxamide CB1 antagonists: The introduction of a hydroxyl group improves the pharmaceutical properties and in vivo efficacy of the series Bioorganic & Medicinal Chemistry Letters ·Bruce A. Ellsworth, Ying Wang, Yeheng Zhu, Annapurna Pendri, Samuel W. Gerritz, Chong‐Qing Sun, Kenneth E. Carlson, Ellien Ajatri Lintas Toety, Gavin Ryan, Yifan Yang, Qi Huang, Neil T. Burford, Mary Jane Cullen, Alan Hargens, Kamelia Behnia, Mary Ann Pelleymounter, William N. Washburn, William R. Ewing	2007	23
15	Reduction of Site-Specific CYP3A-Mediated Metabolism for Dual Angiotensin and Endothelin Receptor Antagonists in Various in Vitro Systems and in Cynomolgus Monkeys Drug Metabolism and Disposition ·Hongjian Zhang, Donglu Zhang, Wenying Li, Ming Yao, Celia D’Arienzo, Yixin Li, William R. Ewing, Zhengxiang Gu, Yeheng Zhu, Natesan Murugesan, 朱满康, W. Griffith Humphreys	2007	9
16	The Design of Competitive, Small-molecule Inhibitors of Coagulation Factor Xa Current Topics in Medicinal Chemistry ·Henry W. Pauls, William R. Ewing	2001	27
17	Synthesis, SAR and in vivo activity of novel thienopyridine sulfonamide pyrrolidinones as factor Xa inhibitors Bioorganic & Medicinal Chemistry Letters ·Michael R. Becker, William R. Ewing, 谷川俊貴, Henry W. Pauls, Cuong Q. Ly, محمد حساين, Helen J. Mason, Yong Mi Choi-Sledeski, Alfred P. Spada, Valeria Chu, Karen Brown, Dennis Colussi, Robert J. Leadley, Ross Bentley, Щеблыкин Сергей Иванович, Charles Kasiewski, İlke Kavuşturan	1999	19
18	Pharmacodynamic Activity and Antithrombotic Efficacy of RPR120844, a Novel Inhibitor of Coagulation Factor Xa Journal of Cardiovascular Pharmacology ·Robert J. Leadley, İlke Kavuşturan, Ross Bentley, Jeffrey S. Bostwick, Charles Kasiewski, Christopher L. Heran, Valeria Chu, Karen Brown, Amy De Los Santos, William R. Ewing, Henry W. Pauls, Alfred P. Spada, Mark H. Perrone, Christopher T. Dunwiddie	1999	15
19	The Occurrence of Iso 24:0 (22-Methyltricosanoic Acid) Fatty Acid in Sphingomyelin of Rat Tissues Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology ·William J. Bettger, Shital Dhoble, the Ireland Array Working Team, William R. Ewing	1998	2
20	Control of Angiogenesis with Synthetic Heparin Substitutes Science ·Judah Folkman, Paul B. Weisz, Madeleine M. Joullié, Milena dos Santos Monteiro, William R. Ewing	1989	235

About William R. Ewing

William R. Ewing is a scholar working on Organic Chemistry, Pharmaceutical Science, Hematology, Genetics and Inorganic Chemistry, having authored 63 papers that have together received 3.1k indexed citations. Recurring topics across this work include Catalytic C–H Functionalization Methods (15 papers), Blood Coagulation and Thrombosis Mechanisms (11 papers), Synthesis and Catalytic Reactions (10 papers), Chemical Synthesis and Analysis (7 papers), Coagulation, Bradykinin, Polyphosphates, and Angioedema (7 papers), Fluorine in Organic Chemistry (6 papers), Vitamin K Research Studies (5 papers) and Receptor Mechanisms and Signaling (5 papers). The work is most often cited by research in Organic Chemistry (2.0k citations), Pharmaceutical Science (240 citations), Inorganic Chemistry (412 citations), Hematology (237 citations) and Process Chemistry and Technology (41 citations). William R. Ewing has collaborated with scholars based in United States, Sweden and Germany. Frequent co-authors include Jennifer X. Qiao, Jin‐Quan Yu, Madeleine M. Joullié, Kap‐Sun Yeung, Henry W. Pauls, Paul B. Weisz, Peter T. W. Cheng, Steven Bloom, David W. C. MacMillan and Judah Folkman. Their work appears in journals such as Journal of the American Chemical Society, Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Angewandte Chemie International Edition and Nature Chemistry.

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