David W. C. MacMillan

71.7k citations

232 papers · 60.2k indexed · 45 hit papers · h-index 114

Organic Chemistry top 0.01%
Inorganic Chemistry top 0.05%
Pharmaceutical Science top 0.01%
Molecular Biology top 0.5%
Renewable Energy, Sustainability and the Environment top 0.2%

Co-authors: Christopher K. Prier Danica A. Rankic Megan H. Shaw Jack Twilton David A. Nagib David A. Nicewicz Alan B. Northrup Anna Allen
Topics: Catalytic C–H Functionalization Methods (112 papers)Radical Photochemical Reactions (104 papers)Asymmetric Synthesis and Catalysis (69 papers)
Cited by: Organic Chemistry Pharmaceutical Science Inorganic Chemistry
Journals: Nature Science Chemical Reviews
Partner nations: United States Spain South Korea

In The Last Decade

David W. C. MacMillan

226 papers receiving 59.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis

2013 8.1k citations David W. C. MacMillan et al. Chemical Reviews profile →
Photoredox Catalysis in Organic Chemistry

2016 2.5k citations David W. C. MacMillan et al. profile →
Merging Photoredox Catalysis with Organocatalysis: The Direct Asymmetric Alkylation of Aldehydes

2008 2.1k citations David A. Nicewicz, David W. C. MacMillan Science profile →
The advent and development of organocatalysis

2008 2.0k citations David W. C. MacMillan profile →
The merger of transition metal and photocatalysis

2017 1.9k citations Chi “Chip” Le, David W. C. MacMillan et al. profile →
Merging photoredox with nickel catalysis: Coupling of α-carboxyl sp ³ -carbons with aryl halides

2014 1.4k citations Zhiwei Zuo, Derek T. Ahneman et al. Science profile →
New Strategies for Organic Catalysis: The First Highly Enantioselective Organocatalytic Diels−Alder Reaction

2000 1.3k citations David W. C. MacMillan et al. Journal of the American Chemical Society profile →
Metallaphotoredox: The Merger of Photoredox and Transition Metal Catalysis

2021 1.2k citations Amy Chan, Ian B. Perry et al. Chemical Reviews profile →
Trifluoromethylation of arenes and heteroarenes by means of photoredox catalysis

2011 1.2k citations David W. C. MacMillan et al. profile →
Synergistic catalysis: A powerful synthetic strategy for new reaction development

2012 1.0k citations David W. C. MacMillan et al. profile →
Discovery of an α-Amino C–H Arylation Reaction Using the Strategy of Accelerated Serendipity

2011 885 citations David W. C. MacMillan et al. Science profile →
Enantioselective α-Trifluoromethylation of Aldehydes via Photoredox Organocatalysis

2009 873 citations David W. C. MacMillan et al. Journal of the American Chemical Society profile →
Alcohols as alkylating agents in heteroarene C–H functionalization

2015 650 citations David W. C. MacMillan et al. profile →
Enantioselective Organocatalytic Reductive Amination

2005 645 citations David W. C. MacMillan et al. Journal of the American Chemical Society profile →
Enantioselective Organo-Cascade Catalysis

2005 637 citations David W. C. MacMillan et al. Journal of the American Chemical Society profile →
The First Direct and Enantioselective Cross-Aldol Reaction of Aldehydes

2002 618 citations Alan B. Northrup, David W. C. MacMillan Journal of the American Chemical Society profile →
Modern strategies in organic catalysis: The advent and development of iminium activation

2006 575 citations G. Lelais, David W. C. MacMillan profile →
Native functionality in triple catalytic cross-coupling: sp ³ C–H bonds as latent nucleophiles

2016 538 citations Jack A. Terrett, David W. C. MacMillan et al. Science profile →
Switching on elusive organometallic mechanisms with photoredox catalysis

2015 535 citations Jack A. Terrett, David W. C. MacMillan et al. profile →
Enantioselective Organocatalytic Indole Alkylations. Design of a New and Highly Effective Chiral Amine for Iminium Catalysis

2002 535 citations David W. C. MacMillan et al. Journal of the American Chemical Society profile →
Aryl amination using ligand-free Ni(II) salts and photoredox catalysis

2016 523 citations Ian W. Davies, David W. C. MacMillan et al. Science profile →
Decarboxylative Arylation of α-Amino Acids via Photoredox Catalysis: A One-Step Conversion of Biomass to Drug Pharmacophore

2014 502 citations Zhiwei Zuo, David W. C. MacMillan Journal of the American Chemical Society profile →
O–H hydrogen bonding promotes H-atom transfer from α C–H bonds for C-alkylation of alcohols

2015 499 citations Jack A. Terrett, David W. C. MacMillan et al. Science profile →
Visible Light Photocatalysis in Organic Chemistry

2018 496 citations David W. C. MacMillan et al. profile →
Photoredox Activation for the Direct β-Arylation of Ketones and Aldehydes

2013 487 citations David W. C. MacMillan et al. Science profile →
Selective sp3 C–H alkylation via polarity-match-based cross-coupling

2017 472 citations Chi “Chip” Le, Yufan Liang et al. profile →
Direct arylation of strong aliphatic C–H bonds

2018 462 citations Ian B. Perry, David W. C. MacMillan et al. profile →
Photoredox-catalyzed deuteration and tritiation of pharmaceutical compounds

2017 461 citations Kazunori Nagao, Andrew J. Hoover et al. Science profile →
Enantioselective Decarboxylative Arylation of α-Amino Acids via the Merger of Photoredox and Nickel Catalysis

2016 460 citations Zhiwei Zuo, David W. C. MacMillan et al. Journal of the American Chemical Society profile →
Photosensitized, energy transfer-mediated organometallic catalysis through electronically excited nickel(II)

2017 455 citations Chi “Chip” Le, David W. C. MacMillan et al. Science profile →
The direct arylation of allylic sp3 C–H bonds via organic and photoredox catalysis

2015 454 citations David W. C. MacMillan et al. profile →
Enantioselective α-Benzylation of Aldehydes via Photoredox Organocatalysis

2010 446 citations David W. C. MacMillan et al. Journal of the American Chemical Society profile →
Direct α‐Arylation of Ethers through the Combination of Photoredox‐Mediated CH Functionalization and the Minisci Reaction

2014 404 citations David W. C. MacMillan et al. profile →
Merging Photoredox and Nickel Catalysis: Decarboxylative Cross-Coupling of Carboxylic Acids with Vinyl Halides

2014 394 citations Stefan J. McCarver, David W. C. MacMillan et al. Journal of the American Chemical Society profile →
Metallaphotoredox-catalysed sp3–sp3 cross-coupling of carboxylic acids with alkyl halides

2016 384 citations David W. C. MacMillan et al. profile →
Photoredox α-Vinylation of α-Amino Acids and N-Aryl Amines

2014 384 citations David W. C. MacMillan et al. Journal of the American Chemical Society profile →
A radical approach to the copper oxidative addition problem: Trifluoromethylation of bromoarenes

2018 382 citations Chi “Chip” Le, David W. C. MacMillan et al. Science profile →
Decarboxylative sp3 C–N coupling via dual copper and photoredox catalysis

2018 370 citations Yufan Liang, David W. C. MacMillan et al. profile →
Microenvironment mapping via Dexter energy transfer on immune cells

2020 267 citations Jacob B. Geri, James V. Oakley et al. Science profile →
Carboxylic Acids as Adaptive Functional Groups in Metallaphotoredox Catalysis

2022 183 citations David W. C. MacMillan et al. profile →
Nontraditional Fragment Couplings of Alcohols and Carboxylic Acids: C(sp³)–C(sp³) Cross-Coupling via Radical Sorting

2022 173 citations Holt A. Sakai, David W. C. MacMillan Journal of the American Chemical Society profile →
General access to cubanes as benzene bioisosteres

2023 108 citations James A. Rossi‐Ashton, Ian B. Perry et al. profile →
Exploiting the Marcus inverted region for first-row transition metal–based photoredox catalysis

2023 106 citations Amy Chan, Holt A. Sakai et al. Science profile →
Alcohol-alcohol cross-coupling enabled by S _H 2 radical sorting

2024 77 citations James A. Rossi‐Ashton, Colin A. Gould et al. Science profile →
Alkene dialkylation by triple radical sorting

2024 69 citations Johnny Wang, David W. C. MacMillan et al. profile →

Peers

Countries citing papers authored by David W. C. MacMillan

Since Specialization

Citations

This map shows the geographic impact of David W. C. MacMillan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David W. C. MacMillan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David W. C. MacMillan more than expected).

Fields of papers citing papers by David W. C. MacMillan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David W. C. MacMillan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David W. C. MacMillan. The network helps show where David W. C. MacMillan may publish in the future.

Co-authorship network of co-authors of David W. C. MacMillan

This figure shows the co-authorship network connecting the top 25 collaborators of David W. C. MacMillan. A scholar is included among the top collaborators of David W. C. MacMillan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David W. C. MacMillan. David W. C. MacMillan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Aminoalkylation of Alkenes Enabled by Triple Radical Sorting 2025 ·Journal of the American Chemical Society ·(unknown),Johnny Wang,Jesús Alcázar,David W. C. MacMillan	20
2	A General Metallaphotoredox Platform for N-Alkylated Sulfoximines as Bioisosteric Building Blocks 2025 ·Journal of the American Chemical Society ·Johannes Großkopf,(unknown),Aimee K. Clarke,David W. C. MacMillan	0
3	Aryl Acid-Alcohol Cross-Coupling: C(sp³)–C(sp²) Bond Formation from Nontraditional Precursors 2025 ·Journal of the American Chemical Society ·Eva Lin,Johnny Wang,Edna Mao,(unknown),Kurtis M. Carsch,(unknown),Ryan E. McNamee,Jeffrey R. Long,Chi “Chip” Le,David W. C. MacMillan	4
4	µMap proximity labeling in living cells reveals stress granule disassembly mechanisms 2024 ·Nature Chemical Biology ·(unknown),Steve D. Knutson,(unknown),David W. C. MacMillan	25
5	Iron-Catalyzed Cross-Electrophile Coupling for the Formation of All-Carbon Quaternary Centers 2024 ·Journal of the American Chemical Society ·(unknown),(unknown),Wei Liu,Marissa N. Lavagnino,David W. C. MacMillan	15
6	Alcohol-alcohol cross-coupling enabled by S _H 2 radical sortingbreakdown → 2024 ·Science ·(unknown),(unknown),(unknown),James A. Rossi‐Ashton,Colin A. Gould,Robert T. Martin,Jesús Alcázar,David W. C. MacMillan	77
7	μMap Photoproximity Labeling Enables Small Molecule Binding Site Mapping 2023 ·Journal of the American Chemical Society ·(unknown),James V. Oakley,Ciaran P. Seath,Jacob B. Geri,Aaron Trowbridge,Dann L. Parker,Frances P. Rodriguez‐Rivera,Adam G. Schwaid,Carlo P. Ramil,Keun Ah Ryu,Cory White,Olugbeminiyi Fadeyi,Rob Oslund,David W. C. MacMillan	33
8	Photoproximity Labeling of Sialylated Glycoproteins (GlycoMap) Reveals Sialylation-Dependent Regulation of Ion Transport 2022 ·Journal of the American Chemical Society ·Claudio F. Meyer,Ciaran P. Seath,Steve D. Knutson,Wenyun Lu,Joshua D. Rabinowitz,David W. C. MacMillan	28
9	Metallaphotoredox: The Merger of Photoredox and Transition Metal Catalysisbreakdown → 2021 ·Chemical Reviews ·Amy Chan,Ian B. Perry,Noah B. Bissonnette,(unknown),Grant A. Edwards,(unknown),Olivia L. Garry,Marissa N. Lavagnino,Beryl X. Li,Yufan Liang,Edna Mao,Agustin Millet,James V. Oakley,Nicholas L. Reed,Holt A. Sakai,Ciaran P. Seath,David W. C. MacMillan	1242
10	A biomimetic S _H 2 cross-coupling mechanism for quaternary sp ³ -carbon formation 2021 ·Science ·Wei Liu,Marissa N. Lavagnino,Colin A. Gould,Jesús Alcázar,David W. C. MacMillan	143
11	Static to inducibly dynamic stereocontrol: The convergent use of racemic β-substituted ketones 2020 ·Science ·(unknown),(unknown),Jacob A. Kautzky,Kazunori Nagao,Andrew J. Meichan,Motoshi Yamauchi,David W. C. MacMillan,Todd K. Hyster	110
12	Microenvironment mapping via Dexter energy transfer on immune cellsbreakdown → 2020 ·Science ·Jacob B. Geri,James V. Oakley,Tamara Reyes Robles,Tao Wang,Stefan J. McCarver,Cory White,Frances P. Rodriguez‐Rivera,Dann L. Parker,Erik C. Hett,Olugbeminiyi Fadeyi,Rob Oslund,David W. C. MacMillan	267
13	HARC as an open-shell strategy to bypass oxidative addition in Ullmann–Goldberg couplings 2020 ·Proceedings of the National Academy of Sciences ·Marissa N. Lavagnino,(unknown),David W. C. MacMillan	46
14	Site-Selective Functionalization of Methionine Residues via Photoredox Catalysis 2020 ·Journal of the American Chemical Society ·(unknown),Beryl X. Li,Richard Y.‐C. Huang,Jennifer X. Qiao,William R. Ewing,David W. C. MacMillan	113
15	Photoredox-catalyzed deuteration and tritiation of pharmaceutical compoundsbreakdown → 2017 ·Science ·(unknown),Kazunori Nagao,Andrew J. Hoover,David Hesk,Nelo R. Rivera,Steven L. Colletti,Ian W. Davies,David W. C. MacMillan	461
16	A General Small-Scale Reactor To Enable Standardization and Acceleration of Photocatalytic Reactions 2017 ·ACS Central Science ·Chi “Chip” Le,Michael K. Wismer,(unknown),Rui Zhang,Donald V. Conway,Guoqing Li,Petr Váchal,Ian W. Davies,David W. C. MacMillan	210
17	Merging photoredox with nickel catalysis: Coupling of α-carboxyl sp ³ -carbons with aryl halidesbreakdown → 2014 ·Science ·Zhiwei Zuo,Derek T. Ahneman,Lingling Chu,Jack A. Terrett,Abigail G. Doyle,David W. C. MacMillan	1376
18	Merging Photoredox Catalysis with Organocatalysis: The Direct Asymmetric Alkylation of Aldehydesbreakdown → 2008 ·Science ·David A. Nicewicz,David W. C. MacMillan	2076
19	Modern strategies in organic catalysis: The advent and development of iminium activationbreakdown → 2006 ·G. Lelais,David W. C. MacMillan	575
20	Two-Step Synthesis of Carbohydrates by Selective Aldol Reactions 2004 ·Science ·Alan B. Northrup,David W. C. MacMillan	336

About David W. C. MacMillan

David W. C. MacMillan is a scholar working on Organic Chemistry, Pharmaceutical Science and Inorganic Chemistry, having authored 232 papers that have together received 60.2k indexed citations. Recurring topics across this work include Catalytic C–H Functionalization Methods (112 papers), Radical Photochemical Reactions (104 papers) and Asymmetric Synthesis and Catalysis (69 papers). The work is most often cited by research in Organic Chemistry (53.9k citations), Pharmaceutical Science (7.3k citations) and Inorganic Chemistry (10.1k citations). David W. C. MacMillan has collaborated with scholars based in United States, Spain and South Korea. Frequent co-authors include Christopher K. Prier, Danica A. Rankic, Megan H. Shaw, Jack Twilton, David A. Nagib, David A. Nicewicz, Alan B. Northrup, Anna Allen, Chi “Chip” Le and Jack A. Terrett. Their work appears in journals such as Nature, Science and Chemical Reviews.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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