Alfred P. Spada

2.5k total citations
44 papers, 1.8k citations indexed

About

Alfred P. Spada is a scholar working on Molecular Biology, Hematology and Organic Chemistry. According to data from OpenAlex, Alfred P. Spada has authored 44 papers receiving a total of 1.8k indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Molecular Biology, 13 papers in Hematology and 9 papers in Organic Chemistry. Recurrent topics in Alfred P. Spada's work include Blood Coagulation and Thrombosis Mechanisms (13 papers), Atrial Fibrillation Management and Outcomes (5 papers) and Liver Disease Diagnosis and Treatment (5 papers). Alfred P. Spada is often cited by papers focused on Blood Coagulation and Thrombosis Mechanisms (13 papers), Atrial Fibrillation Management and Outcomes (5 papers) and Liver Disease Diagnosis and Treatment (5 papers). Alfred P. Spada collaborates with scholars based in United States, Switzerland and United Kingdom. Alfred P. Spada's co-authors include Asher Zilberstein, Martin P. Maguire, Henry W. Pauls, William R. Ewing, Michael R. Myers, J.P. Guilloteau, Michael R. Becker, Alexander Levitzki, Yong Mi Choi-Sledeski and S. Maignan and has published in prestigious journals such as Journal of Biological Chemistry, Circulation and Hepatology.

In The Last Decade

Alfred P. Spada

44 papers receiving 1.7k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Alfred P. Spada United States 22 789 664 241 229 195 44 1.8k
Athanasios Yiotakis Greece 34 1.1k 1.4× 1.7k 2.6× 150 0.6× 172 0.8× 62 0.3× 74 3.1k
Richard M. Keenan United States 23 394 0.5× 576 0.9× 47 0.2× 167 0.7× 60 0.3× 39 1.4k
Roger A. Smith United States 21 890 1.1× 1.4k 2.1× 127 0.5× 149 0.7× 255 1.3× 60 2.8k
Dashyant Dhanak United States 27 396 0.5× 2.0k 3.0× 162 0.7× 89 0.4× 127 0.7× 59 3.2k
Todd W. Rockway United States 20 237 0.3× 387 0.6× 102 0.4× 83 0.4× 162 0.8× 38 940
Robert A. Galemmo United States 19 262 0.3× 494 0.7× 32 0.1× 143 0.6× 76 0.4× 46 1.0k
Brian E. Schultz United States 18 268 0.3× 881 1.3× 90 0.4× 191 0.8× 56 0.3× 33 1.8k
Sylvie M. Guichard United Kingdom 33 555 0.7× 2.3k 3.5× 275 1.1× 202 0.9× 219 1.1× 96 4.0k
Timothy B. Lowinger United States 20 742 0.9× 1.3k 1.9× 121 0.5× 136 0.6× 257 1.3× 53 2.7k
Jay P. Powers United States 21 333 0.4× 455 0.7× 124 0.5× 81 0.4× 83 0.4× 66 1.7k

Countries citing papers authored by Alfred P. Spada

Since Specialization
Citations

This map shows the geographic impact of Alfred P. Spada's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alfred P. Spada with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alfred P. Spada more than expected).

Fields of papers citing papers by Alfred P. Spada

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alfred P. Spada. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alfred P. Spada. The network helps show where Alfred P. Spada may publish in the future.

Co-authorship network of co-authors of Alfred P. Spada

This figure shows the co-authorship network connecting the top 25 collaborators of Alfred P. Spada. A scholar is included among the top collaborators of Alfred P. Spada based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alfred P. Spada. Alfred P. Spada is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Gracia‐Sancho, Jordi, Martí Ortega‐Ribera, Raquel Maeso‐Díaz, et al.. (2019). Emricasan Ameliorates Portal Hypertension and Liver Fibrosis in Cirrhotic Rats Through a Hepatocyte‐Mediated Paracrine Mechanism. Hepatology Communications. 3(7). 987–1000. 45 indexed citations
2.
Mehta, Gautam, Gary Burgess, Mark Morris, et al.. (2017). A Placebo-Controlled, Multicenter, Double-Blind, Phase 2 Randomized Trial of the Pan-Caspase Inhibitor Emricasan in Patients with Acutely Decompensated Cirrhosis. Journal of Clinical and Experimental Hepatology. 8(3). 224–234. 27 indexed citations
3.
Kopec, Anna K., Alfred P. Spada, Patricia C. Contreras, Nigel Mackman, & James P. Luyendyk. (2017). Caspase Inhibition Reduces Hepatic Tissue Factor-Driven Coagulation In Vitro and In Vivo. Toxicological Sciences. 162(2). 396–405. 7 indexed citations
4.
Elbekai, Reem H., et al.. (2015). Carcinogenicity assessment of the pan-caspase inhibitor, emricasan, in Tg.rasH2 mice. Regulatory Toxicology and Pharmacology. 72(2). 169–178. 8 indexed citations
5.
Bilder, Glenda E., Dilip Amin, Lisa Morgan, et al.. (2003). Stent-induced Restenosis in the Swine Coronary Artery Is Inhibited by a Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitor, TKI963. Journal of Cardiovascular Pharmacology. 41(6). 817–829. 8 indexed citations
6.
Wang, He, Barbara Hanney, Alfred P. Spada, et al.. (2003). Potent quinoxaline-Based inhibitors of PDGF receptor tyrosine kinase activity. Part 2: the synthesis and biological activities of RPR127963 an orally bioavailable inhibitor. Bioorganic & Medicinal Chemistry Letters. 13(18). 3097–3100. 136 indexed citations
7.
Guertin, Kevin R., Scott I. Klein, Allison L. Zulli, et al.. (2002). Optimization of the β-Aminoester class of factor Xa inhibitors. part 2: Identification of FXV673 as a potent and selective inhibitor with excellent In vivo anticoagulant activity. Bioorganic & Medicinal Chemistry Letters. 12(12). 1671–1674. 45 indexed citations
8.
He, Wei, Barbara Hanney, Michael R. Myers, et al.. (2002). Benzimidazoles and isosteric compounds as potent and selective factor Xa inhibitors. Bioorganic & Medicinal Chemistry Letters. 12(6). 919–922. 6 indexed citations
9.
Klein, Scott I., Kevin R. Guertin, Allison L. Zulli, et al.. (2002). Optimization of the β-Aminoester class of factor Xa inhibitors. part 1: P4 and side-Chain modifications for improved In vitro potency. Bioorganic & Medicinal Chemistry Letters. 12(12). 1667–1670. 14 indexed citations
10.
Gong, Yong, Henry W. Pauls, Alfred P. Spada, et al.. (2000). Amido-(propyl and allyl)-hydroxybenzamidines: development of achiral inhibitors of factor Xa. Bioorganic & Medicinal Chemistry Letters. 10(3). 217–221. 9 indexed citations
11.
He, Wei, Barbara Hanney, Michael R. Myers, et al.. (2000). Nonbenzamidine compounds as selective factor xa inhibitors. Bioorganic & Medicinal Chemistry Letters. 10(15). 1737–1739. 10 indexed citations
12.
Chu, Valeria, Karen Brown, Dennis Colussi, et al.. (2000). In Vitro Characterization of a Novel Factor Xa Inhibitor, RPR 130737. Thrombosis Research. 99(1). 71–82. 16 indexed citations
13.
Becker, Michael R., William R. Ewing, Henry W. Pauls, et al.. (1999). Synthesis, SAR and in vivo activity of novel thienopyridine sulfonamide pyrrolidinones as factor Xa inhibitors. Bioorganic & Medicinal Chemistry Letters. 9(18). 2753–2758. 19 indexed citations
14.
Leadley, Robert J., Ross Bentley, Jeffrey S. Bostwick, et al.. (1999). Pharmacodynamic Activity and Antithrombotic Efficacy of RPR120844, a Novel Inhibitor of Coagulation Factor Xa. Journal of Cardiovascular Pharmacology. 34(6). 791–799. 15 indexed citations
15.
Klein, Scott I., Kevin R. Guertin, Daniel L. Cheney, et al.. (1998). Identification and Initial Structure−Activity Relationships of a Novel Class of Nonpeptide Inhibitors of Blood Coagulation Factor Xa. Journal of Medicinal Chemistry. 41(4). 437–450. 35 indexed citations
16.
Maguire, Martin P., et al.. (1994). A New Series of PDGF Receptor Tyrosine Kinase Inhibitors: 3-Substituted Quinoline Derivatives. Journal of Medicinal Chemistry. 37(14). 2129–2137. 396 indexed citations
17.
Wasserman, Harry H., et al.. (1992). Singlet oxygen in synthesis. Oxazoles as carbonyl 1,1-dipole synthons.. Tetrahedron Letters. 33(47). 7207–7210. 10 indexed citations
18.
Yoneda, Toshiyuki, R. Lyall, Alfred P. Spada, et al.. (1991). Teatro, Mauá, SP.. PubMed. 51(16). 4430–5. 97 indexed citations
19.
Hsu, Chia‐Yi, et al.. (1991). Kinetic analysis of the inhibition of the epidermal growth factor receptor tyrosine kinase by Lavendustin-A and its analogue.. Journal of Biological Chemistry. 266(31). 21105–21112. 71 indexed citations
20.
Pavlik, James W. & Alfred P. Spada. (1979). Photo-ring contraction reactions of 4-hydroxypyrylium cations. Tetrahedron Letters. 20(46). 4441–4444. 3 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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