William F. Heath

4.0k citations

22 papers · 2.3k indexed · 1 hit paper · h-index 16

Molecular Biology top 5%
Organic Chemistry top 10%
Physiology top 10%
Surgery
Cellular and Molecular Neuroscience top 10%

Co-authors: R. B. Merrifield James P. Tam J. Richard Sportsman Lawrence E. Stramm Toyoshi Inoguchi Teruo Shiba Sven–Erik Bursell George L. King
Topics: Chemical Synthesis and Analysis (8 papers)Pancreatic function and diabetes (4 papers)Chemical Synthesis and Reactions (3 papers)
Cited by: Molecular Biology Clinical Biochemistry Microbiology
Journals: Science Proceedings of the National Academy of Sciences Journal of the American Chemical Society
Partner nations: United States Japan

In The Last Decade

William F. Heath

22 papers receiving 2.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

An SN2 deprotection of synthetic peptides with a low concentration of hydrofluoric acid in dimethyl sulfide: evidence and application in peptide synthesis

1983 478 citations James P. Tam, William F. Heath et al. Journal of the American Chemical Society profile →

Peers

Countries citing papers authored by William F. Heath

Since Specialization

Citations

This map shows the geographic impact of William F. Heath's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William F. Heath with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William F. Heath more than expected).

Fields of papers citing papers by William F. Heath

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William F. Heath. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William F. Heath. The network helps show where William F. Heath may publish in the future.

Co-authorship network of co-authors of William F. Heath

This figure shows the co-authorship network connecting the top 25 collaborators of William F. Heath. A scholar is included among the top collaborators of William F. Heath based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William F. Heath. William F. Heath is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Prevention of Vascular and Neural Dysfunction in Diabetic Rats by C-Peptide 1997 ·Science ·Yasuo Ido,Alessandro Vindigni,K. Chang,Lawrence E. Stramm,Ronald E. Chance,William F. Heath,Richard D. DiMarchi,Enrico Di,Joseph R. Williamson	278
2	Comparison of ELISA and TLC for the Analysis of Promoter Activity When Using the CAT Reporter Gene 1996 ·BioTechniques ·Anne Reifel‐Miller,(unknown),(unknown),(unknown),William F. Heath,Lawrence E. Stramm	1
3	LY290181, an Inhibitor of Diabetes-Induced Vascular Dysfunction, Blocks Protein Kinase C—Stimulated Transcriptional Activation Through Inhibition of Transcription Factor Binding to a Phorbol Response Element 1996 ·Diabetes ·(unknown),William F. Heath,(unknown),(unknown),(unknown),C. P. Dell,(unknown),Joseph R. Williamson,Anne Reifel‐Miller	33
4	(S)-13-[(Dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16,21-dimetheno- 1H,13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-dione (LY333531) and Related Analogues: Isozyme Selective Inhibitors of Protein Kinase Cβ 1996 ·Journal of Medicinal Chemistry ·Michael R. Jirousek,James R. Gillig,Cécile Gonzalez,William F. Heath,John H. McDonald,David A. Neel,Christopher J. Rito,Upinder Singh,Lawrence E. Stramm,(unknown),Matthew F. Baevsky,Lawrence M. Ballas,Steven E. Hall,Leonard L. Winneroski,Margaret M. Faul	274
5	Synthesis of bisindolylmaleimide macrocycles 1995 ·Bioorganic & Medicinal Chemistry Letters ·Michael R. Jirousek,James R. Gillig,David A. Neel,Christopher J. Rito,(unknown),William F. Heath,John H. McDonald,Margaret M. Faul,Leonard L. Winneroski,(unknown),Matthew F. Baevsky,(unknown),Steven E. Hall	12
6	Correlation of diacylglycerol level and protein kinase C activity in rat retina to retinal circulation 1993 ·American Journal of Physiology-Endocrinology and Metabolism ·Teruo Shiba,Toyoshi Inoguchi,J. Richard Sportsman,William F. Heath,Sven–Erik Bursell,George L. King	249
7	Design and implementation of a particle concentration fluorescence method for the detection of HIV-1 protease inhibitors 1992 ·Analytical Biochemistry ·Joseph Manetta,Mei‐Huei T. Lai,Harold E. Osborne,(unknown),Nara Margolin,J. Richard Sportsman,Chris J. Vlahos,S. Betty Yan,William F. Heath	13
8	(A-C-B) human proinsulin, a novel insulin agonist and intermediate in the synthesis of biosynthetic human insulin. 1992 ·Journal of Biological Chemistry ·William F. Heath,Rama M. Belagaje,Gerald S. Brooke,Ronald E. Chance,J. A. Hoffmann,Long Bao Hoang,(unknown),(unknown),Walter N. Shaw,Lawrence J. Slieker	32
9	Glucose Transporter Levels in Tissues of Spontaneously Diabetic Zucker fa/fa Rat (ZDF/drt) and Viable Yellow Mouse (Avy/a) 1992 ·Diabetes ·Lawrence J. Slieker,(unknown),William F. Heath,Harold E. Osborne,(unknown),Joseph Manetta,J. Richard Sportsman	71
10	Mutations in the heparin-binding domains of human basic fibroblast growth factor alter its biological activity 1991 ·Biochemistry ·William F. Heath,Amanda Cantrell,Nancy G. Mayne,S. Richard Jaskunas	31
11	Inhibition of protein kinase C by calphostin C is light-dependent 1991 ·Biochemical and Biophysical Research Communications ·Robert F. Bruns,Freeman D. Miller,Ronald L. Merriman,J. Jeffry Howbert,William F. Heath,Eiji Kobayashi,ISAMI TAKAHASHI,Tatsuya Tamaoki,Hirofumi Nakano	348
12	Presence of Liver CGRP/Amylin Receptors in Only Nonparenchymal Cells and Absence of Direct Regulation of Rat Liver Glucose Metabolism by CGRP/Amylin 1991 ·Diabetes ·Thomas W. Stephens,William F. Heath,(unknown)	33
13	Improved deprotection of cysteine‐containing peptides in HF 1986 ·International journal of peptide & protein research ·William F. Heath,James P. Tam,R. B. Merrifield	20
14	Mechanisms for the removal of benzyl protecting groups in synthetic peptides by trifluoromethanesulfonic acid-trifluoroacetic acid-dimethyl sulfide 1986 ·Journal of the American Chemical Society ·James P. Tam,William F. Heath,R. B. Merrifield	159
15	A synthetic approach to structure-function relationships in the murine epidermal growth factor molecule. 1986 ·Proceedings of the National Academy of Sciences ·William F. Heath,R. B. Merrifield	75
16	S_N 1 and S_N 2 mechanisms for the deprotection of synthetic peptides by hydrogen fluoride 1983 ·International journal of peptide & protein research ·James P. Tam,William F. Heath,R. B. Merrifield	83
17	An SN2 deprotection of synthetic peptides with a low concentration of hydrofluoric acid in dimethyl sulfide: evidence and application in peptide synthesisbreakdown → 1983 ·Journal of the American Chemical Society ·James P. Tam,William F. Heath,R. B. Merrifield	478
18	Improved deprotection in solid phase peptide synthesis: deprotection of Nⁱ-formyl-tryptophan to tryptophan in low concentrations of HF in Me₂S–p- thiocresol mixtures 1982 ·Journal of the Chemical Society Chemical Communications ·William F. Heath,James P. Tam,R. B. Merrifield	9
19	Improved deprotection in solid phase peptide synthesis: quantitative reduction of methionine sulfoxide to methionine during HF cleavage 1982 ·Tetrahedron Letters ·James P. Tam,William F. Heath,R. B. Merrifield	34
20	Improved deprotection in solid phase reptide synthesis: removal of protecting groups from synthetic peptides by an SN2 mechanism with low concentrations of HF in dimethylsulfide 1982 ·Tetrahedron Letters ·James P. Tam,William F. Heath,R. B. Merrifield	15

About William F. Heath

William F. Heath is a scholar working on Organic Chemistry, Molecular Biology and Ophthalmology, having authored 22 papers that have together received 2.3k indexed citations. Recurring topics across this work include Chemical Synthesis and Analysis (8 papers), Pancreatic function and diabetes (4 papers) and Chemical Synthesis and Reactions (3 papers). The work is most often cited by research in Molecular Biology (1.5k citations), Clinical Biochemistry (123 citations) and Microbiology (95 citations). William F. Heath has collaborated with scholars based in United States and Japan. Frequent co-authors include R. B. Merrifield, James P. Tam, J. Richard Sportsman, Lawrence E. Stramm, Toyoshi Inoguchi, Teruo Shiba, Sven–Erik Bursell, George L. King, Tatsuya Tamaoki and Hirofumi Nakano. Their work appears in journals such as Science, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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