R. B. Merrifield

25.4k total citations · 14 hit papers
179 papers, 20.0k citations indexed

About

R. B. Merrifield is a scholar working on Molecular Biology, Organic Chemistry and Microbiology. According to data from OpenAlex, R. B. Merrifield has authored 179 papers receiving a total of 20.0k indexed citations (citations by other indexed papers that have themselves been cited), including 150 papers in Molecular Biology, 56 papers in Organic Chemistry and 30 papers in Microbiology. Recurrent topics in R. B. Merrifield's work include Chemical Synthesis and Analysis (116 papers), Antimicrobial Peptides and Activities (30 papers) and Carbohydrate Chemistry and Synthesis (28 papers). R. B. Merrifield is often cited by papers focused on Chemical Synthesis and Analysis (116 papers), Antimicrobial Peptides and Activities (30 papers) and Carbohydrate Chemistry and Synthesis (28 papers). R. B. Merrifield collaborates with scholars based in United States, Sweden and Spain. R. B. Merrifield's co-authors include James P. Tam, Hans G. Boman, Stephen B. H. Kent, David Andreu, William F. Heath, Virender K. Sarin, Bernd Gutte, Alexander R. Mitchell, David Wade and Anita Boman and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

R. B. Merrifield

179 papers receiving 18.5k citations

Hit Papers

Solid Phase Peptide Synthesis. I. The Synthesis of a Tetr... 1963 2026 1984 2005 1963 1981 1990 1969 1983 2.0k 4.0k 6.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide
    1963 6.3k citations R. B. Merrifield Journal of the American Chemical Society profile →
  2. Quantitative monitoring of solid-phase peptide synthesis by the ninhydrin reaction
    1981 957 citations James P. Tam, R. B. Merrifield et al. profile →
  3. All-D amino acid-containing channel-forming antibiotic peptides.
    1990 579 citations David Wade, Anita Boman et al. profile →
  4. Solid‐Phase Peptide Synthesis
    1969 559 citations R. B. Merrifield Advances in enzymology and related areas of molecular biology/Advances in enzymology and related subjects profile →
  5. An SN2 deprotection of synthetic peptides with a low concentration of hydrofluoric acid in dimethyl sulfide: evidence and application in peptide synthesis
    1983 478 citations James P. Tam, R. B. Merrifield et al. Journal of the American Chemical Society profile →
  6. Solid-Phase Peptide Synthesis. III. An Improved Synthesis of Bradykinin*
    1964 459 citations R. B. Merrifield Biochemistry profile →
  7. Automated Synthesis of Peptides
    1965 430 citations R. B. Merrifield profile →
  8. Synthesis of the antibacterial peptide cecropin A(1-33)
    1982 309 citations R. B. Merrifield, Hans G. Boman et al. Biochemistry profile →
  9. A new synthetic route to tert-butyloxycarbonylaminoacyl-4-(oxymethyl)phenylacetamidomethyl-resin, an improved support for solid-phase peptide synthesis
    1978 285 citations R. B. Merrifield et al. The Journal of Organic Chemistry profile →
  10. The Synthesis of Ribonuclease A
    1971 235 citations R. B. Merrifield et al. Journal of Biological Chemistry profile →
  11. tert-Butoxycarbonylaminoacyl-4-(oxymethyl)phenylacetamidomethyl-resin, a more acid-resistant support for solid-phase peptide synthesis
    1976 201 citations R. B. Merrifield et al. Journal of the American Chemical Society profile →
  12. Solid Phase Peptide Synthesis. II. The Synthesis of Bradykinin
    1964 198 citations R. B. Merrifield Journal of the American Chemical Society profile →
  13. Total synthesis of an enzyme with ribonuclease A activity
    1969 192 citations R. B. Merrifield et al. Journal of the American Chemical Society profile →
  14. Carboxyl-catalyzed intramolecular aminolysis. Side reaction in solid-phase peptide synthesis
    1972 171 citations R. B. Merrifield et al. Journal of the American Chemical Society profile →

Peers

R. B. Merrifield
James P. Tam United States
Stephen B. H. Kent United States
Ernest Giralt Spain
Rob M. J. Liskamp Netherlands
Tom W. Muir United States
Samuel H. Gellman United States
Nobutaka Fujii Japan
Philip E. Dawson United States
Carlo Pedone Italy
Charles M. Deber Canada
James P. Tam United States
R. B. Merrifield
Citations per year, relative to R. B. Merrifield R. B. Merrifield (= 1×) peers James P. Tam

Countries citing papers authored by R. B. Merrifield

Since Specialization
Citations

This map shows the geographic impact of R. B. Merrifield's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by R. B. Merrifield with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites R. B. Merrifield more than expected).

Fields of papers citing papers by R. B. Merrifield

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by R. B. Merrifield. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by R. B. Merrifield. The network helps show where R. B. Merrifield may publish in the future.

Co-authorship network of co-authors of R. B. Merrifield

This figure shows the co-authorship network connecting the top 25 collaborators of R. B. Merrifield. A scholar is included among the top collaborators of R. B. Merrifield based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with R. B. Merrifield. R. B. Merrifield is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Marassi, Francesca M., Stanley J. Opella, Padmaja Juvvadi, & R. B. Merrifield. (1999). Orientation of Cecropin A Helices in Phospholipid Bilayers Determined by Solid-State NMR Spectroscopy. Biophysical Journal. 77(6). 3152–3155. 76 indexed citations
2.
Unson, Cecilia G., et al.. (1998). Positively Charged Residues at Positions 12, 17, and 18 of Glucagon Ensure Maximum Biological Potency. Journal of Biological Chemistry. 273(17). 10308–10312. 18 indexed citations
3.
4.
Vunnam, Satyanarayana, Padmaja Juvvadi, & R. B. Merrifield. (1997). Synthesis and antibacterial action of cecropin and proline‐arginine‐rich peptides from pig intestine. Journal of Peptide Research. 49(1). 59–66. 68 indexed citations
5.
Juvvadi, Padmaja, et al.. (1996). Hydrophobic Effects on Antibacterial and Channel‐forming Properties of Cecropin A–Melittin Hybrids. Journal of Peptide Science. 2(4). 223–232. 39 indexed citations
6.
Unson, Cecilia G., Aaron M. Cypess, Paul K. Goldsmith, et al.. (1995). Characterization of Deletion and Truncation Mutants of the Rat Glucagon Receptor. Journal of Biological Chemistry. 270(46). 27720–27727. 83 indexed citations
7.
Mitchell, Scott A., et al.. (1995). d‐Enantiomers of 15‐residue cecropin A‐melittin hybrids. International journal of peptide & protein research. 46(3-4). 214–220. 56 indexed citations
8.
Unson, Cecilia G., et al.. (1994). Roles of Aspartic Acid 15 and 21 in Glucagon Action: Receptor Anchor and Surrogates for Aspartic Acid 9. Biochemistry. 33(22). 6884–6887. 21 indexed citations
9.
Unson, Cecilia G., Douglas Macdonald, & R. B. Merrifield. (1993). The Role of Histidine-1 in Glucagon Action. Archives of Biochemistry and Biophysics. 300(2). 747–750. 35 indexed citations
10.
Andreu, David, Josep Ubach, Anita Boman, et al.. (1992). Shortened cecropin A‐melittin hybrids Significant size reduction retains potent antibiotic activity. FEBS Letters. 296(2). 190–194. 228 indexed citations
11.
Wade, David, David Andreu, Scott A. Mitchell, et al.. (1992). Antibacterial peptides designed as analogs or hybrids of cecropins and melittin. International journal of peptide & protein research. 40(5). 429–436. 137 indexed citations
12.
Unson, Cecilia G., Ellen Gurzenda, & R. B. Merrifield. (1989). Biological activities of des-His1[Glu9]glucagon amide, a glucagon antagonist. Peptides. 10(6). 1171–1177. 99 indexed citations
13.
Boman, Hans G., et al.. (1989). Antibacterial and antimalarial properties of peptides that are cecropin‐melittin hybrids. FEBS Letters. 259(1). 103–106. 266 indexed citations
14.
15.
Merrifield, R. B., et al.. (1987). 4‐Methoxybenzyloxycarbonyl amino acids in solid phase peptide synthesis. International journal of peptide & protein research. 30(5). 662–667. 6 indexed citations
16.
17.
Merrifield, R. B., et al.. (1978). 9-(2-Sulfo)fluorenylmethyloxycarbonyl chloride, a new reagent for the purification of synthetic peptides. The Journal of Organic Chemistry. 43(25). 4808–4816. 60 indexed citations
18.
Tam, James P., et al.. (1977). Selective cleavage of protected amino acids and peptides from oxyacyl resins by an 18-crown-6 complex of potassium cyanide. Tetrahedron Letters. 18(46). 4001–4004. 13 indexed citations
19.
Merrifield, R. B.. (1969). Solid‐Phase Peptide Synthesis. Advances in enzymology and related areas of molecular biology/Advances in enzymology and related subjects. 32. 221–296. 559 indexed citations breakdown →
20.
Vigneaud, Vincent du, et al.. (1968). Synthesis of deaminooxytocin by the solid phase method. Journal of the American Chemical Society. 90(5). 1323–1325. 51 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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