William E. Hughes

4.4k citations

65 papers · 3.4k indexed · 2 hit papers · h-index 31

Impact in

Cell Biology top 1%
- Cellular transport and secretion
Molecular Biology top 5%
- DNA and Nucleic Acid Chemistry
- Advanced biosensing and bioanalysis techniques
- Extracellular vesicles in disease
- Protein Kinase Regulation and GTPase Signaling
- Metabolism, Diabetes, and Cancer

Papers in

Biophysics 11
- Advanced Fluorescence Microscopy Techniques 9
Cell Biology 20
- Cellular transport and secretion 10
- Cellular Mechanics and Interactions 5

Co-authors: Peter J. Parker David E. James Daniel Christ Trevor J. Biden Frank T. Cooke Romain Rouet Peter Schofield Aaron L. Moye
Journals: Journal of Biological Chemistry (8 papers)Nature Communications (3 papers)Traffic (3 papers)Biochemical Journal (3 papers)Diabetes (2 papers)
Partner nations: Australia United States United Kingdom

In The Last Decade

William E. Hughes

64 papers receiving 3.4k citations

Hit Papers

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Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise 2018 · 483 citations

Peers

Countries citing papers authored by William E. Hughes

Since Specialization

Citations

This map shows the geographic impact of William E. Hughes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William E. Hughes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William E. Hughes more than expected).

Fields of papers citing papers by William E. Hughes

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William E. Hughes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William E. Hughes. The network helps show where William E. Hughes may publish in the future.

Co-authorship network

The 25 scholars most cited alongside William E. Hughes, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with William E. Hughes Line = papers co-authored together William E. Hughes links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Nuclear actin and DNA replication stress regulate telomere maintenance by telomerase Nature Communications ·Hong K. Nam, Mladen Valkov, Victor Gualdras de la Cruz, Wai K. Choy, Sheik S. Rahman, William E. Hughes, Dilpreet Singh, Scott B. Cohen, Anthony J. Cesare, Noa Lamm, Tracy M. Bryan	2025	0
2	ER stress disrupts insulin release in murine models of type 2 diabetes by impairing retromer action and constitutive secretion Cell Reports ·Nancy Sue, Frank Leslie Thomas, Ebru Boslem, Kwan Yi Chu, Chenxu Yan, 杜寻梦, William E. Hughes, 多和健雄, Deborah S. Barkauskas, Louise Cottle, Helen E. Thomas, Carsten Schmitz‐Peiffer, Yan‐Chuan Shi, Paul Timpson, David Herrmann, Martin Whitham, Trevor J. Biden	2025	1
3	Mitochondria facilitate neuronal differentiation by metabolising nuclear-encoded RNA Cell Communication and Signaling ·Béline Yaëlle Hermet, Mary Simonian, William E. Hughes, Claire E. Shepherd, Neil Hunter, Ramin Hamidi Farahani	2024	2
4	Annexin A6 and NPC1 regulate LDL-inducible cell migration and distribution of focal adhesions Scientific Reports ·Naelah Alghufily, Monira Hoque, SY Ng, Syed Sultan Beevi, Dinko Stančić-Rokotov, Ahmed Othman Almadfaa, Kendelle J. Murphy, William E. Hughes, Blake J. Cochran, Albert Lu, Francesc Tebar, Andrew J. Hoy, Paul Timpson, Kerry‐Anne Rye, Carlos Enrich, Carles Rentero, Thomas Grewal	2022	15
5	Adipocyte-specific deletion of IL-6 does not attenuate obesity-induced weight gain or glucose intolerance in mice American Journal of Physiology-Endocrinology and Metabolism ·Martin Whitham, Martin Pál, Tim Petzold, Marit Hjorth, Casey L. Egan, Julia S. Brunner, Emma Estévez, Peter Iliades, Teguh Triyanto, Saskia Reibe, William E. Hughes, Nur Alfika, Juan Hidalgo, Mark A. Febbraio	2019	24
6	I-motif DNA structures are formed in the nuclei of human cells Nature Chemistry ·Mahdi Zeraati, D.B. Langley, Peter Schofield, Aaron L. Moye, Romain Rouet, William E. Hughes, Tracy M. Bryan, Marcel E. Dinger, Daniel Christ Hit paper breakdown →	2018	433
7	Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish Nature Communications ·Anne K. Lagendijk, Guillermo A. Gómez, Sungmin Baek, Daniel Hesselson, William E. Hughes, Scott Paterson, Daniel E. Conway, Heinz‐Georg Belting, Markus Affolter, K. A. Smith, Martin A. Schwartz, Alpha S. Yap, Benjamin M. Hogan	2017	76
8	IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2 Nature Communications ·Christoph Jandl, Sue Min Liu, Pablo F. Cañete, Joanna Warren, William E. Hughes, Alexis Vogelzang, Kylie E. Webster, Maria E. Craig, Gülbû Uzel, Alexander L. Dent, Polina Stepensky, Bärbel Keller, Klaus Warnatz, Jonathan Sprent, Charles M. King	2017	91
9	Annexin A6 is a scaffold for PKCα to promote EGFR inactivation Oncogene ·Meryem Koese, Carles Rentero, Bhavani Prasad Kota, Monira Hoque, Rose Cairns, Peta Wood, Sandra Vilà de Muga, Meritxell Reverter, Anna Álvarez-Guaita, Katia Monastyrskaya, William E. Hughes, Alexander Swarbrick, Francesc Tebar, Roger J. Daly, Carlos Enrich, Thomas Grewal	2012	61
10	Redox control of β2‐glycoprotein I–von Willebrand factor interaction by thioredoxin‐1 Journal of Thrombosis and Haemostasis ·Freda Passam, Soheila Rahgozar, Miao Qi, Mark J. Raftery, Jason W.H. Wong, Kumiko Tanaka, Yiannis Ioannou, Nugroho Tri Adi, Rosalie Gemmell, Jinda Qi, Bill Giannakopoulos, William E. Hughes, Philip J. Hogg, Steven A. Krilis	2010	52
11	Gab2 regulates cytoskeletal organization and migration of mammary epithelial cells by modulating RhoA activation Molecular Biology of the Cell ·Maria Teresa Herrera Abreu, William E. Hughes, Samantha Rajapaksa, Ruth J. Lyons, Danny Rickwood, Brigid C. Browne, Haley L. Bennett, Pascal Vallotton, Tilman Brummer, Roger J. Daly	2010	20
12	Suppression of NF-κB Activity by Parthenolide Induces X-Ray Sensitivity through Inhibition of Split-Dose Repair in TP53 Null Prostate Cancer Cells Radiation Research ·Yingjie Hu, Douglas A. Miller, Helen Chin-Sinex, Luca Spinardi, William E. Hughes, Christopher J. Sweeney, Marc S. Mendonca	2009	25
13	Canine erythrocytes express the P2X₇receptor: greatly increased function compared with human erythrocytes American Journal of Physiology-Regulatory, Integrative and Comparative Physiology ·Ronald Sluyter, Anne N. Shemon, William E. Hughes, Claudio Gorlier, J. Ravikanth, Guy D. Eslick, Rosanne M. Taylor, James S. Wiley	2007	34
14	The Diacylglycerol-dependent Translocation of Ras Guanine Nucleotide-releasing Protein 4 inside a Human Mast Cell Line Results in Substantial Phenotypic Changes, Including Expression of Interleukin 13 Receptor α2 Journal of Biological Chemistry ·Gregory Katsoulotos, Miao Qi, Jian Qi, Kumiko Tanaka, William E. Hughes, Timothy J. Molloy, Roberto Adachi, Richard L Stevens, Steven A. Krilis	2007	14
15	Phosphorylation of Nonmuscle Myosin Heavy Chain IIA on Ser1917 Is Mediated by Protein Kinase CβII and Coincides with the Onset of Stimulated Degranulation of RBL-2H3 Mast Cells The Journal of Immunology ·Russell I. Ludowyke, Zehra Elgundi, Tanya A. Kranenburg, Justine Stehn, Carsten Schmitz‐Peiffer, William E. Hughes, Trevor J. Biden	2006	45
16	Inhibition of H-Ras and MAPK is compensated by PKC-dependent pathways in annexin A6 expressing cells Cellular Signalling ·Carles Rentero, 李兴芳, Peta Wood, Francesc Tebar, Sandra Vilà de Muga, Laia Cubells, Iñaki de Diego, Marjolein Bosch, William E. Hughes, Albert Pol, Kerry‐Anne Rye, Carlos Enrich, Thomas Grewal	2005	34
17	Akt Mediates Insulin-stimulated Phosphorylation of Ndrg2 Journal of Biological Chemistry ·James G. Burchfield, 朱传贤, J. D. CLOUGH, William E. Hughes, Valerie C. Wasinger, Garry L. Corthals, Tomohiko Okuda, Hisato Kondoh, Trevor J. Biden, Carsten Schmitz‐Peiffer	2004	71
18	A Cortactin-CD2-associated Protein (CD2AP) Complex Provides a Novel Link between Epidermal Growth Factor Receptor Endocytosis and the Actin Cytoskeleton Journal of Biological Chemistry ·Danielle K. Lynch, Benjamin Antunes, Ruth J. Lyons, William E. Hughes, Gillian M. Lehrbach, Valerie C. Wasinger, Garry L. Corthals, Stuart J. Cordwell, Roger J. Daly	2003	180
19	The Sac phosphatase domain Current Biology ·William E. Hughes	2001	5
20	Effects of local hyperthermia on tumor microcirculation: I. Blood flow rate studies International Journal of Radiation OncologyBiologyPhysics ·Bahman Emami, Gilbert H. Nussbaum, Randall K. Ten Haken, Nina Hahn, William E. Hughes	1979	2

About William E. Hughes

William E. Hughes is a scholar working on Biophysics, Cell Biology, Software, Molecular Biology and Immunology and Allergy, having authored 65 papers that have together received 3.4k indexed citations. Recurring topics across this work include Cellular transport and secretion (10 papers), Advanced Fluorescence Microscopy Techniques (9 papers), Protein Kinase Regulation and GTPase Signaling (9 papers), Pancreatic function and diabetes (9 papers), Software Engineering Research (5 papers), Cellular Mechanics and Interactions (5 papers), Diabetes and associated disorders (5 papers) and Metabolism, Diabetes, and Cancer (5 papers). The work is most often cited by research in Cell Biology (838 citations), Molecular Biology (2.1k citations), Immunology and Allergy (139 citations), Biophysics (123 citations) and Cancer Research (310 citations). William E. Hughes has collaborated with scholars based in Australia, United States and United Kingdom. Frequent co-authors include Peter J. Parker, David E. James, Daniel Christ, Trevor J. Biden, Frank T. Cooke, Romain Rouet, Peter Schofield, Aaron L. Moye, D.B. Langley and Tracy M. Bryan. Their work appears in journals such as Journal of Biological Chemistry, Nature Communications, Traffic, Biochemical Journal and Diabetes.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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