Jonathan Sprent

36.2k total citations · 14 hit papers
291 papers, 29.9k citations indexed

About

Jonathan Sprent is a scholar working on Immunology, Oncology and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, Jonathan Sprent has authored 291 papers receiving a total of 29.9k indexed citations (citations by other indexed papers that have themselves been cited), including 267 papers in Immunology, 40 papers in Oncology and 29 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in Jonathan Sprent's work include T-cell and B-cell Immunology (214 papers), Immune Cell Function and Interaction (186 papers) and Immunotherapy and Immune Responses (154 papers). Jonathan Sprent is often cited by papers focused on T-cell and B-cell Immunology (214 papers), Immune Cell Function and Interaction (186 papers) and Immunotherapy and Immune Responses (154 papers). Jonathan Sprent collaborates with scholars based in United States, Australia and South Korea. Jonathan Sprent's co-authors include Charles D. Surh, David F. Tough, Onur Boyman, Robert Korngold, Hidehiro Kishimoto, Siquan Sun, Inkyu Hwang, David Lo, Susan R. Webb and Yacov Ron and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Jonathan Sprent

289 papers receiving 29.0k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The role of interleukin-2 during homeostasis and activation of the immune system

2012 1.2k citations Onur Boyman, Jonathan Sprent profile →
Potent and Selective Stimulation of Memory-Phenotype CD8+ T Cells In Vivo by IL-15

1998 1.1k citations Inkyu Hwang, Jonathan Sprent et al. profile →
Induction of Bystander T Cell Proliferation by Viruses and Type I Interferon in Vivo

1996 926 citations David F. Tough, Jonathan Sprent et al. Science profile →
Homeostasis of Naive and Memory T Cells

2008 914 citations Charles D. Surh, Jonathan Sprent profile →
T-cell apoptosis detected in situ during positive and negative selection in the thymus

1994 896 citations Charles D. Surh, Jonathan Sprent profile →
IL-7 is critical for homeostatic proliferation and survival of naïve T cells

2001 788 citations Jonathan Sprent, Charles D. Surh et al. Proceedings of the National Academy of Sciences profile →
Turnover of naive- and memory-phenotype T cells.

1994 784 citations David F. Tough, Jonathan Sprent The Journal of Experimental Medicine profile →
Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection

2005 768 citations Ganesh Kolumam, Sunil Thomas et al. The Journal of Experimental Medicine profile →
Selective Stimulation of T Cell Subsets with Antibody-Cytokine Immune Complexes

2006 719 citations Onur Boyman, Marek Kovář et al. Science profile →
Interleukin (IL)-15 and IL-7 Jointly Regulate Homeostatic Proliferation of Memory Phenotype CD8+ Cells but Are Not Required for Memory Phenotype CD4+ Cells

2002 651 citations Jonathan Sprent, Charles D. Surh et al. The Journal of Experimental Medicine profile →
The Peptide Ligands Mediating Positive Selection in the Thymus Control T Cell Survival and Homeostatic Proliferation in the Periphery

1999 640 citations Jonathan Sprent, Charles D. Surh et al. profile →
A Fundamental Role for Interleukin-21 in the Generation of T Follicular Helper Cells

2008 584 citations Alexis Vogelzang, Helen M. McGuire et al. profile →
A monoclonal antibody discriminating between subsets of T and B cells.

1981 515 citations Jonathan Sprent et al. The Journal of Immunology profile →
Lethal graft-versus-host disease after bone marrow transplantation across minor histocompatibility barriers in mice. Prevention by removing mature T cells from marrow.

1978 429 citations Jonathan Sprent et al. The Journal of Experimental Medicine profile →

Peers

Countries citing papers authored by Jonathan Sprent

Since Specialization

Citations

This map shows the geographic impact of Jonathan Sprent's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jonathan Sprent with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jonathan Sprent more than expected).

Fields of papers citing papers by Jonathan Sprent

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jonathan Sprent. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jonathan Sprent. The network helps show where Jonathan Sprent may publish in the future.

Co-authorship network of co-authors of Jonathan Sprent

This figure shows the co-authorship network connecting the top 25 collaborators of Jonathan Sprent. A scholar is included among the top collaborators of Jonathan Sprent based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jonathan Sprent. Jonathan Sprent is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Optimising IL-2 for Cancer Immunotherapy 2024 ·Immune Network ·Jonathan Sprent, Onur Boyman	7
2	Food antigens drive spontaneous IgE elevation in the absence of commensal microbiota 2019 ·Science Advances ·Sung‐Wook Hong, O Eunju, Jun Young Lee, Minji Lee, Daehee Han, Hyun‐Ja Ko, Jonathan Sprent, Charles D. Surh, Kwang Soon Kim	32
3	Cell surface polysaccharides of Bifidobacterium bifidum induce the generation of Foxp3 ⁺ regulatory T cells 2018 ·Science Immunology ·Ravi Verma, Changhon Lee, (unknown), Jaeu Yi, Kwang Soon Kim, Ambarnil Ghosh, Seohyun Byun, Choong‐Gu Lee, Hye-Ji Kang, Gi-Cheon Kim, Chang‐Duk Jun, Gwénaël Jan, Chang‐Hee Suh, Ju‐Yang Jung, Jonathan Sprent, Dipayan Rudra, Cristina De Castro, Antonio Molinaro, Charles D. Surh, Sin‐Hyeog Im	186
4	Dendritic Cell Internalization of α-Galactosylceramide from CD8 T Cells Induces Potent Antitumor CD8 T-cell Responses 2011 ·Cancer Research ·Dong Hoon Choi, Kwang Soon Kim, Se Hwan Yang, Doo Hyun Chung, Boyeong Song, Jonathan Sprent, Jaeho Cho, Young Chul Sung	8
5	Loss of parity between IL-2 and IL-21 in the NOD Idd3 locus 2009 ·Proceedings of the National Academy of Sciences ·Helen M. McGuire, Alexis Vogelzang, Natasha Hill, Malin Flodström‐Tullberg, Jonathan Sprent, Charles M. King	50
6	In vivo expansion of T reg cells with IL-2–mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression 2009 ·The Journal of Experimental Medicine ·Kylie E. Webster, Stacey N. Walters, Rachel E. Kohler, Tomáš Mrkvan, Onur Boyman, Charles D. Surh, Shane T. Grey, Jonathan Sprent	426
7	The Lymphopenic Environment of CD132 (Common γ-Chain)-Deficient Hosts Elicits Rapid Homeostatic Proliferation of Naive T Cells via IL-15 2008 ·The Journal of Immunology ·Chris Ramsey, Mark P. Rubinstein, (unknown), Jae-Ho Cho, Jonathan Sprent, Charles D. Surh	30
8	IL-7/Anti-IL-7 mAb Complexes Restore T Cell Development and Induce Homeostatic T Cell Expansion without Lymphopenia 2008 ·The Journal of Immunology ·Onur Boyman, Chris Ramsey, (unknown), Jonathan Sprent, Charles D. Surh	105
9	Selective Stimulation of T Cell Subsets with Antibody-Cytokine Immune Complexes breakdown → 2006 ·Science ·Onur Boyman, Marek Kovář, Mark P. Rubinstein, Charles D. Surh, Jonathan Sprent	719
10	Regulation of naive T cell function by the NF-κB2 pathway 2006 ·Nature Immunology ·Naozumi Ishimaru, Hidehiro Kishimoto, Yoshio Hayashi, Jonathan Sprent	71
11	Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection breakdown → 2005 ·The Journal of Experimental Medicine ·Ganesh Kolumam, Sunil Thomas, Lucas Thompson, Jonathan Sprent, Kaja Murali‐Krishna	768
12	An IFN-γ-Dependent Pathway Controls Stimulation of Memory Phenotype CD8+ T Cell Turnover In Vivo by IL-12, IL-18, and IFN-γ 2001 ·The Journal of Immunology ·David F. Tough, Xiaohong Zhang, Jonathan Sprent	91
13	Role of the Actin Cytoskeleton in T Cell Absorption and Internalization of Ligands from APC 2001 ·The Journal of Immunology ·Inkyu Hwang, Jonathan Sprent	53
14	Presidential address to the American Association of Immunologists. Stimulating naive T cells. 1999 ·PubMed ·Jonathan Sprent	14
15	Anti-viral immunity: Spotting virus-specific T cells 1998 ·Current Biology ·David F. Tough, Jonathan Sprent	16
16	Factors influencing the fate of T cells responding to Mls antigens. 1992 ·PubMed ·(unknown), (unknown), Jonathan Sprent	15
17	Antigen-presenting cells for Lyt-2+ cells. I. Stimulation of unprimed Lyt-2+ cells by H-2 different Thy-1-Ia- cells prepared from spleen and bone marrow. 1988 ·The Journal of Immunology ·Jonathan Sprent, Michele L. Schaefer	8
18	Analysis of T hybridomas prepared from a T cell clone with three specificities. Recognition of self + X and allo-H-2 determinants segregates from recognition of Mlsa determinants. 1988 ·The Journal of Immunology ·Susan R. Webb, Akiko Okamoto, Jonathan Sprent	8
19	Effects of blocking helper T cell induction in vivo with anti-Ia antibodies. Possible role of I-A/E hybrid molecules as restriction elements. 1980 ·The Journal of Experimental Medicine ·Jonathan Sprent	62
20	Restricted helper function of F1 hybrid T cells positively selected to heterologous erythrocytes in irradiated parental strain mice. II. Evidence for restrictions affecting helper cell induction and T-B collaboration, both mapping to the K-end of the H-2 complex. 1978 ·The Journal of Experimental Medicine ·Jonathan Sprent	151

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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