Wesley K. Kroeze

6.7k citations

38 papers · 4.9k indexed · 3 hit papers · h-index 27

Molecular Biology top 2%
Cellular and Molecular Neuroscience top 0.5%
Computational Theory and Mathematics top 1%
Psychiatry and Mental health top 2%
Physiology top 5%

Co-authors: Bryan L. Roth Douglas J. Sheffler Kurt Kristiansen Xi‐Ping Huang Katherine Lansu John D. McCorvy Sandra J. Hufeisen Noah Sciaky
Topics: Receptor Mechanisms and Signaling (30 papers)Neurotransmitter Receptor Influence on Behavior (12 papers)Neuropeptides and Animal Physiology (11 papers)
Cited by: Cellular and Molecular Neuroscience Biological Psychiatry Molecular Biology
Journals: Nature Science Proceedings of the National Academy of Sciences
Partner nations: United States Denmark Argentina

In The Last Decade

Wesley K. Kroeze

37 papers receiving 4.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia

2004 893 citations Bryan L. Roth, Wesley K. Kroeze et al. profile →
H1-Histamine Receptor Affinity Predicts Short-Term Weight Gain for Typical and Atypical Antipsychotic Drugs

2003 637 citations Wesley K. Kroeze, Sandra J. Hufeisen et al. Neuropsychopharmacology profile →
PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome

2015 519 citations Wesley K. Kroeze, Maria F. Sassano et al. Nature Structural & Molecular Biology profile →

Peers

Countries citing papers authored by Wesley K. Kroeze

Since Specialization

Citations

This map shows the geographic impact of Wesley K. Kroeze's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Wesley K. Kroeze with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Wesley K. Kroeze more than expected).

Fields of papers citing papers by Wesley K. Kroeze

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Wesley K. Kroeze. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Wesley K. Kroeze. The network helps show where Wesley K. Kroeze may publish in the future.

Co-authorship network of co-authors of Wesley K. Kroeze

This figure shows the co-authorship network connecting the top 25 collaborators of Wesley K. Kroeze. A scholar is included among the top collaborators of Wesley K. Kroeze based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Wesley K. Kroeze. Wesley K. Kroeze is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	In silico design of novel probes for the atypical opioid receptor MRGPRX2 2017 ·Nature Chemical Biology ·Katherine Lansu,Joel Karpiak,Jing Liu,Xi‐Ping Huang,John D. McCorvy,Wesley K. Kroeze,Tao Che,Hiroshi Nagase,Frank I. Carroll,Jian Jin,Brian K. Shoichet,Bryan L. Roth	217
2	Discovery and Characterization of Novel GPR39 Agonists Allosterically Modulated by Zinc 2016 ·Molecular Pharmacology ·Seiji Sato,Xi‐Ping Huang,Wesley K. Kroeze,Bryan L. Roth	44
3	Integrated Approaches for Genome-wide Interrogation of the Druggable Non-olfactory G Protein-coupled Receptor Superfamily 2015 ·Journal of Biological Chemistry ·Bryan L. Roth,Wesley K. Kroeze	61
4	Single Amino Acid Variation Underlies Species-Specific Sensitivity to Amphibian Skin-Derived Opioid-like Peptides 2015 ·Chemistry & Biology ·Eyal Vardy,Maria F. Sassano,Andrew J. Rennekamp,Wesley K. Kroeze,Philip D. Mosier,Richard B. Westkaemper,(unknown),Vsevolod Katritch,Raymond C. Stevens,Randall T. Peterson,Bryan L. Roth	11
5	Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65 2015 ·Nature ·Xi‐Ping Huang,Joel Karpiak,Wesley K. Kroeze,Hu Zhu,Xin Chen,Sheryl S. Moy,(unknown),Viktoriya D. Nikolova,Martilias S. Farrell,Sheng Wang,Thomas J. Mangano,Deepak A. Deshpande,Alice Jiang,Raymond B. Penn,Jian Jin,Beverly H. Koller,Terry Kenakin,Brian K. Shoichet,Bryan L. Roth	197
6	PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRomebreakdown → 2015 ·Nature Structural & Molecular Biology ·Wesley K. Kroeze,Maria F. Sassano,Xi‐Ping Huang,Katherine Lansu,John D. McCorvy,Philippe Giguère,Noah Sciaky,Bryan L. Roth	519
7	Tuning up the right signal: chemical and genetic approaches to study GPCR functions 2013 ·Current Opinion in Cell Biology ·Philippe Giguère,Wesley K. Kroeze,Bryan L. Roth	19
8	Quantitative Analysis of Focused A-To-I RNA Editing Sites by Ultra-High-Throughput Sequencing in Psychiatric Disorders 2012 ·PLoS ONE ·Hu Zhu,Daniel J. Urban,(unknown),(unknown),Wesley K. Kroeze,Piotr A. Mieczkowski,James C. Overholser,George Jurjus,Lesa Dieter,Gouri Mahajan,Grażyna Rajkowska,Zefeng Wang,Patrick F. Sullivan,Craig A. Stockmeier,Bryan L. Roth	33
9	Antagonist Functional Selectivity: 5-HT2A Serotonin Receptor Antagonists Differentially Regulate 5-HT2A Receptor Protein Level In Vivo 2011 ·Journal of Pharmacology and Experimental Therapeutics ·Prem N. Yadav,Wesley K. Kroeze,Martilias S. Farrell,Bryan L. Roth	62
10	Deorphanization of Novel Peptides and Their Receptors 2010 ·The AAPS Journal ·Akihiko Ozawa,Iris Lindberg,Bryan L. Roth,Wesley K. Kroeze	26
11	The Presynaptic Component of the Serotonergic System is Required for Clozapine's Efficacy 2010 ·Neuropsychopharmacology ·Prem N. Yadav,Atheir I. Abbas,Martilias S. Farrell,Vincent Setola,Noah Sciaky,Xi‐Ping Huang,Wesley K. Kroeze,LaTasha K. Crawford,David Piel,Michael J. Keiser,John J. Irwin,Brian K. Shoichet,Evan S. Deneris,Jay A. Gingrich,Sheryl G. Beck,Bryan L. Roth	51
12	Genetic Deletion of p90 Ribosomal S6 Kinase 2 Alters Patterns of 5-Hydroxytryptamine2A Serotonin Receptor Functional Selectivity 2009 ·Molecular Pharmacology ·Ryan T. Strachan,Noah Sciaky,Mark R. Cronan,Wesley K. Kroeze,Bryan L. Roth	28
13	The Human Polyomavirus, JCV, Uses Serotonin Receptors to Infect Cells 2004 ·Science ·Gwendolyn F. Elphick,William Querbes,(unknown),Gretchen V. Gee,Sylvia Eash,Kate Manley,Aisling S. Dugan,Megan L. Stanifer,Anushree Bhatnagar,Wesley K. Kroeze,Bryan L. Roth,Walter J. Atwood	331
14	H1-Histamine Receptor Affinity Predicts Short-Term Weight Gain for Typical and Atypical Antipsychotic Drugsbreakdown → 2003 ·Neuropsychopharmacology ·Wesley K. Kroeze,Sandra J. Hufeisen,(unknown),(unknown),S Steinberg,Paul Ernsberger,Karu Jayathilake,Herbert Y. Meltzer,Bryan L. Roth	637
15	Evidence for a Model of Agonist-induced Activation of 5-Hydroxytryptamine 2A Serotonin Receptors That Involves the Disruption of a Strong Ionic Interaction between Helices 3 and 6 2002 ·Journal of Biological Chemistry ·Д. А. Шапиро,Kurt Kristiansen,David M. Weiner,Wesley K. Kroeze,Bryan L. Roth	142
16	Similar ultrastructural distribution of the 5-HT2A serotonin receptor and microtubule-associated protein MAP1A in cortical dendrites of adult rat 2002 ·Neuroscience ·(unknown),Kenneth C. Watkins,Bryan L. Roth,Wesley K. Kroeze,Pierrette Gaudreau,Nicole Leclerc,L. Descarries	79
17	Differential Modes of Agonist Binding to 5-Hydroxytryptamine2A Serotonin Receptors Revealed by Mutation and Molecular Modeling of Conserved Residues in Transmembrane Region 5 2000 ·Molecular Pharmacology ·Д. А. Шапиро,Kurt Kristiansen,Wesley K. Kroeze,Bryan L. Roth	14
18	Structure and Function of the Third Intracellular Loop of the 5‐Hydroxytryptamine_2A Receptor: The Third Intracellular Loop Is α‐Helical and Binds Purified Arrestins 1999 ·Journal of Neurochemistry ·(unknown),Wesley K. Kroeze,(unknown),J.A. Gray,(unknown),Edward Hyde,Vsevolod V. Gurevich,Jeffrey Benovic,(unknown)	88
19	G protein-coupled receptor (GPCR) trafficking in the central nervous system: relevance for drugs of abuse 1998 ·Drug and Alcohol Dependence ·(unknown),David L. Willins,Wesley K. Kroeze	52
20	Serotonin 5-HT2A Receptors: Molecular Biology and Mechanisms of Regulation 1998 ·PubMed ·Bryan L. Roth,Susan A. Berry,Wesley K. Kroeze,David L. Willins,Kurt Kristiansen	91

About Wesley K. Kroeze

Wesley K. Kroeze is a scholar working on Cellular and Molecular Neuroscience, Biological Psychiatry and Molecular Biology, having authored 38 papers that have together received 4.9k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (30 papers), Neurotransmitter Receptor Influence on Behavior (12 papers) and Neuropeptides and Animal Physiology (11 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (1.9k citations), Biological Psychiatry (181 citations) and Molecular Biology (2.8k citations). Wesley K. Kroeze has collaborated with scholars based in United States, Denmark and Argentina. Frequent co-authors include Bryan L. Roth, Douglas J. Sheffler, Kurt Kristiansen, Xi‐Ping Huang, Katherine Lansu, John D. McCorvy, Sandra J. Hufeisen, Noah Sciaky, Karu Jayathilake and Philippe Giguère. Their work appears in journals such as Nature, Science and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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