Vincent B. Chen

53.4k citations

22 papers · 35.1k indexed · 4 hit papers · h-index 16

Impact in

Structural Biology top 0.2%
Molecular Biology top 0.05%
- RNA and protein synthesis mechanisms
- Protein Structure and Dynamics
- RNA modifications and cancer
- Biochemical and Molecular Research
- RNA Research and Splicing

Papers in

Structural Biology 3
- Advanced Electron Microscopy Techniques and Applications 3
Materials Chemistry 14
- Enzyme Structure and Function 14

Co-authors: David Richardson Jane S. Richardson Jeffrey J. Headd Gary J. Kapral D.A. Keedy W.B. Arendall Nigel W. Moriarty Paul D. Adams
Journals: Acta Crystallographica Section D Structural Biology (4 papers)Protein Science (3 papers)Journal of Applied Crystallography (2 papers)Journal of Structural Biology (1 paper)Journal of Biomolecular NMR (1 paper)
Partner nations: United States United Kingdom France

In The Last Decade

Vincent B. Chen

21 papers receiving 35.0k citations

Hit Papers

align trajectories log scale

MolProbity: More and better reference data for improved all‐atom structure validation 2017 · 2.8k citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2017 Protein Science
2011 Methods
2010 Acta Crystallographica Section D Biological Crystallography
2009 Acta Crystallographica Section D Biological Crystallography

Peers

Countries citing papers authored by Vincent B. Chen

Since Specialization

Citations

This map shows the geographic impact of Vincent B. Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Vincent B. Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Vincent B. Chen more than expected).

Fields of papers citing papers by Vincent B. Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Vincent B. Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Vincent B. Chen. The network helps show where Vincent B. Chen may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Vincent B. Chen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Vincent B. Chen Line = papers co-authored together Vincent B. Chen links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Categorizing prediction modes within low-pLDDT regions of AlphaFold 2 structures: near-predictive, pseudostructure and barbed wire Acta Crystallographica Section D Structural Biology ·Christopher J. Williams, Vincent B. Chen, David C. Richardson, Jane S. Richardson	2025	0
2	Structures of the DarR transcription regulator reveal unique modes of second messenger and DNA binding Nature Communications ·Maria A. Schumacher, Mohit Vishwas Saini, Vincent B. Chen, Raul Salinas	2023	3
3	The bad and the good of trends in model building and refinement for sparse-data regions: pernicious forms of overfitting versus good new tools and predictions Acta Crystallographica Section D Structural Biology ·Jane S. Richardson, Christopher J. Williams, Vincent B. Chen, Michael G. Prisant, David Richardson	2023	4
4	Improving SARS-CoV-2 structures: Peer review by early coordinate release Biophysical Journal ·Tristan I. Croll, Christopher J. Williams, Vincent B. Chen, David Richardson, Jane S. Richardson	2021	14
5	CERES: a cryo-EM re-refinement system for continuous improvement of deposited models Acta Crystallographica Section D Structural Biology ·Dorothée Liebschner, Pavel V. Afonine, Nigel W. Moriarty, Billy K. Poon, Vincent B. Chen, Paul D. Adams	2020	15
6	New tools in MolProbity validation: CaBLAM for CryoEM backbone, UnDowser to rethink “waters,” and NGL Viewer to recapture online 3D graphics Protein Science ·Michael G. Prisant, Christopher J. Williams, Vincent B. Chen, Jane S. Richardson, David Richardson	2019	99
7	Assessment of detailed conformations suggests strategies for improving cryoEM models: Helix at lower resolution, ensembles, pre-refinement fixups, and validation at multi-residue length scale Journal of Structural Biology ·Jane S. Richardson, Christopher J. Williams, Lizbeth L. Videau, Vincent B. Chen, David Richardson	2018	15
8	Model validation: local diagnosis, correction and when to quit Acta Crystallographica Section D Structural Biology ·Jane S. Richardson, Christopher J. Williams, Bradley J. Hintze, Vincent B. Chen, Michael G. Prisant, Lizbeth L. Videau, David Richardson	2018	25
9	Caloric Restriction Engages Hepatic RNA Processing Mechanisms in Rhesus Monkeys Cell Metabolism ·Timothy W. Rhoads, Maggie S. Burhans, Vincent B. Chen, Paul D. Hutchins, Matthew J. P. Rush, Josef P. Clark, Jaime L. Stark, Sean J. McIlwain, Hamid R. Eghbalnia, Derek M. Pavelec, Irene M. Ong, John M. Denu, John L. Markley, Joshua J. Coon, Ricki J. Colman, Rozalyn M. Anderson	2018	51
10	MolProbity: More and better reference data for improved all‐atom structure validation Protein Science ·Christopher J. Williams, Jeffrey J. Headd, Nigel W. Moriarty, Michael G. Prisant, Lizbeth L. Videau, L.N. Deis, Vishal Verma, D.A. Keedy, Bradley J. Hintze, Vincent B. Chen, Swati Jain, Steven M. Lewis, W.B. Arendall, Jack Snoeyink, Paul D. Adams, Simon C. Lovell, Jane S. Richardson, David Richardson Hit paper breakdown →	2017	2815
11	MolProbity for the masses–of data Journal of Biomolecular NMR ·Vincent B. Chen, Jonathan R. Wedell, Rephael Wenger, Eldon L. Ulrich, John L. Markley	2015	38
12	Use of knowledge-based restraints in phenix.refine to improve macromolecular refinement at low resolution Acta Crystallographica Section D Biological Crystallography ·Jeffrey J. Headd, Nathaniel Echols, Pavel V. Afonine, Ralf W. Grosse‐Kunstleve, Vincent B. Chen, Nigel W. Moriarty, David Richardson, Jane S. Richardson, Paul D. Adams	2012	195
13	Probing Conformational Changes in Human DNA Topoisomerase IIα by Pulsed Alkylation Mass Spectrometry Journal of Biological Chemistry ·M Tucker, Kang Jang Hwa, Ziqiang Guan, Vincent B. Chen, Tao‐shih Hsieh	2012	7
14	The Phenix software for automated determination of macromolecular structures Methods ·Paul D. Adams, Pavel V. Afonine, G. Bunkóczi, Vincent B. Chen, Nathaniel Echols, Jeffrey J. Headd, Li‐Wei Hung, Swati Jain, Gary J. Kapral, Raquel Dias Jales, Airlie J. McCoy, Nigel W. Moriarty, Robert D. Oeffner, Randy J. Read, David Richardson, Jane S. Richardson, Thomas C. Terwilliger, Peter H. Zwart Hit paper breakdown →	2011	691
15	PHENIX: a comprehensive Python-based system for macromolecular structure solution Acta Crystallographica Section D Biological Crystallography ·Paul D. Adams, Pavel V. Afonine, G. Bunkóczi, Vincent B. Chen, Ian Davis, Nathaniel Echols, Jeffrey J. Headd, Li‐Wei Hung, Gary J. Kapral, Ralf W. Grosse‐Kunstleve, Airlie J. McCoy, Nigel W. Moriarty, Robert D. Oeffner, Randy J. Read, David Richardson, Jane S. Richardson, Thomas C. Terwilliger, Peter H. Zwart Hit paper breakdown →	2010	18966
16	phenix.model_vs_data: a high-level tool for the calculation of crystallographic model and data statistics Journal of Applied Crystallography ·Pavel V. Afonine, Ralf W. Grosse‐Kunstleve, Vincent B. Chen, Jeffrey J. Headd, Nigel W. Moriarty, Jane S. Richardson, David Richardson, Alexandre Urzhumtsev, Peter H. Zwart, Paul D. Adams	2010	105
17	MolProbity: all-atom structure validation for macromolecular crystallography Acta Crystallographica Section D Biological Crystallography ·Vincent B. Chen, W.B. Arendall, Jeffrey J. Headd, D.A. Keedy, Robert M. Immormino, Gary J. Kapral, Laura W. Murray, Jane S. Richardson, David Richardson Hit paper breakdown →	2009	11415
18	KING (Kinemage, Next Generation): A versatile interactive molecular and scientific visualization program Protein Science ·Vincent B. Chen, Ian Davis, David Richardson	2009	128
19	KinImmerse: Macromolecular VR for NMR ensembles SHILAP Revista de lepidopterología ·Faju Wu, David J. Zielinski, Vincent B. Chen, Ian Davis, 马彦雷, Rachael Brady, Jane S. Richardson, David Richardson	2009	17
20	The other 90% of the protein: Assessment beyond the Cαs for CASP8 template‐based and high‐accuracy models Proteins Structure Function and Bioinformatics ·D.A. Keedy, Christopher J. Williams, Jeffrey J. Headd, W.B. Arendall, Vincent B. Chen, Gary J. Kapral, Robert A. Gillespie, Faju Wu, Adam Zemła, David Richardson, Jane S. Richardson	2009	61

About Vincent B. Chen

Vincent B. Chen is a scholar working on Structural Biology, Materials Chemistry, Computer Graphics and Computer-Aided Design, Molecular Biology and Computational Theory and Mathematics, having authored 22 papers that have together received 35.1k indexed citations. Recurring topics across this work include Protein Structure and Dynamics (14 papers), Enzyme Structure and Function (14 papers), RNA and protein synthesis mechanisms (7 papers), Computational Drug Discovery Methods (3 papers), Advanced Electron Microscopy Techniques and Applications (3 papers), Glycosylation and Glycoproteins Research (2 papers), Bacterial Genetics and Biotechnology (2 papers) and Genomics and Phylogenetic Studies (2 papers). The work is most often cited by research in Structural Biology (700 citations), Molecular Biology (25.3k citations), Molecular Medicine (995 citations), Endocrinology (932 citations) and Cell Biology (3.0k citations). Vincent B. Chen has collaborated with scholars based in United States, United Kingdom and France. Frequent co-authors include David Richardson, Jane S. Richardson, Jeffrey J. Headd, Gary J. Kapral, D.A. Keedy, W.B. Arendall, Nigel W. Moriarty, Paul D. Adams, Laura W. Murray and Robert M. Immormino. Their work appears in journals such as Acta Crystallographica Section D Structural Biology, Protein Science, Journal of Applied Crystallography, Journal of Structural Biology and Journal of Biomolecular NMR.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact