Nigel W. Moriarty

66.2k citations

77 papers · 37.9k indexed · 10 hit papers · h-index 35

Impact in

Structural Biology top 0.1%
Molecular Biology top 0.05%
- RNA and protein synthesis mechanisms
- Protein Structure and Dynamics
- Biochemical and Molecular Research
- RNA modifications and cancer
- RNA Research and Splicing

Papers in

Structural Biology 6
Materials Chemistry 52
- Enzyme Structure and Function 45
- Machine Learning in Materials Science 9
- X-ray Diffraction in Crystallography 7

Co-authors: Paul D. Adams Ralf W. Grosse‐Kunstleve Thomas C. Terwilliger Pavel V. Afonine Peter H. Zwart Randy J. Read Li‐Wei Hung Jeffrey J. Headd
Journals: Acta Crystallographica Section D Structural Biology (17 papers)Journal of Applied Crystallography (4 papers)Chemical Physics Letters (3 papers)Acta Crystallographica Section A Foundations and Advances (2 papers)International Journal of Chemical Kinetics (2 papers)
Partner nations: United States United Kingdom China

In The Last Decade

Nigel W. Moriarty

76 papers receiving 37.8k citations

Hit Papers

10 papers align trajectories log scale

New tools for the analysis and validation of cryo-EM maps and atomic models 2018 · 516 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2018 Acta Crystallographica Section D Structural Biology
2017 Protein Science
2017 Acta Crystallographica Section D Structural Biology
2012 Acta Crystallographica Section D Biological Crystallography
2011 Methods
2010 Acta Crystallographica Section D Biological Crystallography
2009 Acta Crystallographica Section D Biological Crystallography
2009 Acta Crystallographica Section D Biological Crystallography
2007 Acta Crystallographica Section D Biological Crystallography
2002 Acta Crystallographica Section D Biological Crystallography

Peers

Countries citing papers authored by Nigel W. Moriarty

Since Specialization

Citations

This map shows the geographic impact of Nigel W. Moriarty's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nigel W. Moriarty with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nigel W. Moriarty more than expected).

Fields of papers citing papers by Nigel W. Moriarty

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nigel W. Moriarty. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nigel W. Moriarty. The network helps show where Nigel W. Moriarty may publish in the future.

Co-authors

The 25 scholars most cited alongside Nigel W. Moriarty, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Nigel W. Moriarty Line = papers co-authored together Nigel W. Moriarty links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	AQuaRef: machine learning accelerated quantum refinement of protein structures Nature Communications ·R.I. Zubatyuk, Małgorzata Biczysko, Kavindri Ranasinghe, Nigel W. Moriarty, Hatice Gökcan, Holger Kruse, Billy K. Poon, Paul D. Adams, Mark P. Waller, Adrián E. Roitberg, Olexandr Isayev, Pavel V. Afonine	2025	2
2	New targets and procedures for validating the valence geometry of nucleic acid structures Nucleic Acids Research ·Jiří Černý, Robert A. Nicholls, Dariusz Brzeziński, Helen M. Berman, Mirosław Gilski, Robbie P Joosten, Marcin Kowiel, Catherine L Lawson, Nigel W. Moriarty, J P Richardson, Bohdan Schneider, (unknown), Christopher J. Williams, Mariusz Jaskólski, Martin Egli	2025	1
3	Protonation of histidine rings using quantum-mechanical methods Acta Crystallographica Section D Structural Biology ·Nigel W. Moriarty, Jonathan E. Moussa, Paul D. Adams	2024	0
4	Characterization of lignin-degrading enzyme PmdC, which catalyzes a key step in the synthesis of polymer precursor 2-pyrone-4,6-dicarboxylic acid Journal of Biological Chemistry ·Andria V. Rodrigues, Nigel W. Moriarty, Ramu Kakumanu, Andy DeGiovanni, J.H. Pereira, Jennifer Gin, Yan Chen, Edward E.K. Baidoo, Christopher J. Petzold, Paul D. Adams	2024	2
5	Optimal clustering for quantum refinement of biomolecular structures: Q\|R#4 Theoretical Chemistry Accounts ·Yaru Wang, Holger Kruse, Nigel W. Moriarty, Mark P. Waller, Pavel V. Afonine, Małgorzata Biczysko	2023	2
6	Overall protein structure quality assessment using hydrogen-bonding parameters Acta Crystallographica Section D Structural Biology ·Pavel V. Afonine, Oleg V. Sobolev, Nigel W. Moriarty, Thomas C. Terwilliger, Paul D. Adams	2023	4
7	Improved joint X-ray and neutron refinement procedure in Phenix Acta Crystallographica Section D Structural Biology ·Dorothée Liebschner, Pavel V. Afonine, Billy K. Poon, Nigel W. Moriarty, Paul D. Adams	2023	6
8	CERES: a cryo-EM re-refinement system for continuous improvement of deposited models Acta Crystallographica Section D Structural Biology ·Dorothée Liebschner, Pavel V. Afonine, Nigel W. Moriarty, Billy K. Poon, Vincent B. Chen, Paul D. Adams	2020	15
9	Real-space quantum-based refinement for cryo-EM: Q \| R #3 Acta Crystallographica Section D Structural Biology ·Lum Wang, Holger Kruse, Oleg V. Sobolev, Nigel W. Moriarty, Mark P. Waller, Pavel V. Afonine, Małgorzata Biczysko	2020	8
10	What are the current limits on determination of protonation state using neutron macromolecular crystallography? Methods in enzymology on CD-ROM/Methods in enzymology ·Dorothée Liebschner, Pavel V. Afonine, Nigel W. Moriarty, Paul D. Adams	2020	3
11	Including crystallographic symmetry in quantum-based refinement: Q \| R #2 Acta Crystallographica Section D Structural Biology ·Min Zheng, Małgorzata Biczysko, Yanting Xu, Nigel W. Moriarty, Holger Kruse, Alexandre Urzhumtsev, Mark P. Waller, Pavel V. Afonine	2019	12
12	Evaluation of models determined by neutron diffraction and proposed improvements to their validation and deposition Acta Crystallographica Section D Structural Biology ·Dorothée Liebschner, Pavel V. Afonine, Nigel W. Moriarty, Paul Langan, Paul D. Adams	2018	15
13	New tools for the analysis and validation of cryo-EM maps and atomic models Acta Crystallographica Section D Structural Biology ·Pavel V. Afonine, Bruno P. Klaholz, Nigel W. Moriarty, Billy K. Poon, Oleg V. Sobolev, Thomas C. Terwilliger, Paul D. Adams, Alexandre Urzhumtsev Hit paper breakdown →	2018	516
14	Solving the scalability issue in quantum-based refinement: Q\|R#1 Acta Crystallographica Section D Structural Biology ·Min Zheng, Nigel W. Moriarty, Yanting Xu, Jeffrey R. Reimers, Pavel V. Afonine, Mark P. Waller	2017	18
15	Polder maps: improving OMIT maps by excluding bulk solvent Acta Crystallographica Section D Structural Biology ·Dorothée Liebschner, Pavel V. Afonine, Nigel W. Moriarty, Billy K. Poon, Oleg V. Sobolev, Thomas C. Terwilliger, Paul D. Adams Hit paper breakdown →	2017	495
16	DiSCaMB: a software library for aspherical atom model X-ray scattering factor calculations with CPUs and GPUs Journal of Applied Crystallography ·Michał Leszek Chodkiewicz, Szymon Migacz, Witold R. Rudnicki, Anna Makal, Jarosław Kalinowski, Nigel W. Moriarty, Ralf W. Grosse‐Kunstleve, Pavel V. Afonine, Paul D. Adams, P.M. Dominiak	2017	38
17	Use of knowledge-based restraints in phenix.refine to improve macromolecular refinement at low resolution Acta Crystallographica Section D Biological Crystallography ·Jeffrey J. Headd, Nathaniel Echols, Pavel V. Afonine, Ralf W. Grosse‐Kunstleve, Vincent B. Chen, Nigel W. Moriarty, David Richardson, Jane S. Richardson, Paul D. Adams	2012	195
18	Towards automated crystallographic structure refinement with phenix.refine Acta Crystallographica Section D Biological Crystallography ·Pavel V. Afonine, Ralf W. Grosse‐Kunstleve, Nathaniel Echols, Jeffrey J. Headd, Nigel W. Moriarty, Marat Mustyakimov, Thomas C. Terwilliger, Alexandre Urzhumtsev, Peter H. Zwart, Paul D. Adams Hit paper breakdown →	2012	4181
19	Joint X-ray and neutron refinement withphenix.refine Acta Crystallographica Section D Biological Crystallography ·Pavel V. Afonine, Marat Mustyakimov, Ralf W. Grosse‐Kunstleve, Nigel W. Moriarty, Paul Langan, Paul D. Adams	2010	231
20	Automated ligand fitting by core-fragment fitting and extension into density Acta Crystallographica Section D Biological Crystallography ·Thomas C. Terwilliger, Herbert E. Klei, Paul D. Adams, Nigel W. Moriarty, Judith D. Cohn	2006	93

About Nigel W. Moriarty

Nigel W. Moriarty is a scholar working on Structural Biology, Materials Chemistry, Physical and Theoretical Chemistry, Fluid Flow and Transfer Processes and Molecular Biology, having authored 77 papers that have together received 37.9k indexed citations. Recurring topics across this work include Enzyme Structure and Function (45 papers), Protein Structure and Dynamics (36 papers), Advanced Chemical Physics Studies (14 papers), Crystallography and molecular interactions (10 papers), Computational Drug Discovery Methods (9 papers), Machine Learning in Materials Science (9 papers), RNA and protein synthesis mechanisms (8 papers) and X-ray Diffraction in Crystallography (7 papers). The work is most often cited by research in Structural Biology (807 citations), Molecular Biology (26.8k citations), Molecular Medicine (1.2k citations), Endocrinology (1.1k citations) and Cell Biology (3.1k citations). Nigel W. Moriarty has collaborated with scholars based in United States, United Kingdom and China. Frequent co-authors include Paul D. Adams, Ralf W. Grosse‐Kunstleve, Thomas C. Terwilliger, Pavel V. Afonine, Peter H. Zwart, Randy J. Read, Li‐Wei Hung, Jeffrey J. Headd, Airlie J. McCoy and Nathaniel Echols. Their work appears in journals such as Acta Crystallographica Section D Structural Biology, Journal of Applied Crystallography, Chemical Physics Letters, Acta Crystallographica Section A Foundations and Advances and International Journal of Chemical Kinetics.

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