Adriana Heguy

33.4k citations

178 papers · 14.0k indexed · 6 hit papers · h-index 60

Impact in

Genetics top 0.2%
- Glioma Diagnosis and Treatment
- Myeloproliferative Neoplasms: Diagnosis and Treatment
Cancer Research top 0.5%
- Cancer Genomics and Diagnostics

Papers in

Cancer Research 31
- Cancer Genomics and Diagnostics 14
Genetics 16
- Glioma Diagnosis and Treatment 10

Co-authors: Michael Karin Agnès Viale Ronald G. Crystal Robert G. Roeder Ross L. Levine Robert I. Richards Igor Dolgalev Claus Scheidereit
Journals: Cancer Research (9 papers)Journal of Clinical Oncology (9 papers)Molecular and Cellular Biology (8 papers)Blood (6 papers)Clinical Cancer Research (5 papers)
Partner nations: United States Italy Germany

In The Last Decade

Adriana Heguy

173 papers receiving 13.7k citations

Hit Papers

6 papers align trajectories log scale

Lupus nephritis is linked to disease-activity associated expansions and immunity to a gut commensal 2019 · 302 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2019 Annals of the Rheumatic Diseases
2018 Nature Medicine
2012 Science
2012 Nature
2012 Nature Genetics
2010 New England Journal of Medicine

Peers

Countries citing papers authored by Adriana Heguy

Since Specialization

Citations

This map shows the geographic impact of Adriana Heguy's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Adriana Heguy with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Adriana Heguy more than expected).

Fields of papers citing papers by Adriana Heguy

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Adriana Heguy. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Adriana Heguy. The network helps show where Adriana Heguy may publish in the future.

Co-authors

The 25 scholars most cited alongside Adriana Heguy, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Adriana Heguy Line = papers co-authored together Adriana Heguy links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Apolipoprotein E2 Expression Alters Endosomal Pathways in a Mouse Model With Increased Brain Exosome Levels During Aging Traffic ·Katherine Y. Peng, Braison Liemisa, Jonathan Pasato, Pasquale D’Acunzo, Monika Pawlik, Adriana Heguy, Sai C. Penikalapati, Amanda Labuza, Harshitha Pidikiti, Melissa J. Alldred, Stephen D. Ginsberg, Efrat Levy, Paul M. Mathews	2024	2
2	Remdesivir Resistance in Transplant Recipients With Persistent Coronavirus Disease 2019 Clinical Infectious Diseases ·John I Hogan, Ralf Duerr, Dacia Dimartino, Christian Marier, Sarah Hochman, Sameer Mehta, Guiqing Wang, Adriana Heguy	2022	64
3	Interleukin-17 governs hypoxic adaptation of injured epithelium Science ·Piotr Konieczny, Yue Xing, Ikjot Sidhu, Ipsita Subudhi, Kody Mansfield, Brandon Hsieh, Douglas E. Biancur, Samantha B. Larsen, Michael Cammer, Dongqing Li, Ning Xu, Cynthia A. Loomis, Adriana Heguy, Anastasia N. Tikhonova, Aristotelis Tsirigos, Shruti Naik	2022	137
4	Multimodal single-cell analysis of cutaneous T-cell lymphoma reveals distinct subclonal tissue-dependent signatures Blood ·Alberto Herrera, Anthony Cheng, Eleni P. Mimitou, Angelina Seffens, Dean David George, Michal Bar‐Natan, Adriana Heguy, Kelly V. Ruggles, José U. Scher, Kenneth B. Hymes, Jo‐Ann Latkowski, Niels Ødum, Marshall E. Kadin, Zhengqing Ouyang, Larisa J. Geskin, Peter Smibert, Terkild B. Buus, Sergei B. Koralov	2021	45
5	Serial single-cell profiling analysis of metastatic TNBC during Nab-paclitaxel and pembrolizumab treatment Breast Cancer Research and Treatment ·Jiehui Deng, Aatish Thennavan, Suhagi Shah, Ece Bagdatlioglu, Natalie Klar, Adriana Heguy, Christian Marier, Peter Meyn, Yutong Zhang, Kristen Labbe, Christina Almonte, Michelle Krogsgaard, Charles M. Perou, Kwok‐Kin Wong, Sylvia Adams	2020	14
6	Immune Response and Microbiota Profiles during Coinfection with Plasmodium vivax and Soil-Transmitted Helminths mBio ·Alice V. Easton, Mayra Raciny-Aleman, Victor Liu, Erica Ruan, Christian Marier, Adriana Heguy, María Fernanda Yasnot, Ana Rodrı́guez, P’ng Loke	2020	16
7	Radiotherapy induces responses of lung cancer to CTLA-4 blockade Nature Medicine ·Silvia C. Formenti, Nils-Petter Rudqvist, Encouse B. Golden, Benjamin T. Cooper, Erik Wennerberg, Claire Lhuillier, Claire Vanpouille‐Box, Kent Friedman, Lucas Ferrari de Andrade, Kai W. Wucherpfennig, Adriana Heguy, Naoko Imai, Sacha Gnjatic, Ryan Emerson, Xi Kathy Zhou, Tuo Zhang, Abraham Chachoua, Sandra Demaria Hit paper breakdown →	2018	640
8	NF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition Cancer Discovery ·María E.R. García-Rendueles, Julio C. Ricarte‐Filho, Brian R. Untch, Iñigo Landa, Jeffrey A. Knauf, Francesca Voza, Vicki E. Smith, Ian Ganly, Barry S. Taylor, Yogindra Persaud, Gisele Oler, Yuqiang Fang, Suresh C. Jhanwar, Agnès Viale, Adriana Heguy, Kety Huberman, Filippo G. Giancotti, Ronald Ghossein, James A. Fagin	2015	99
9	Rare variants in the neurotrophin signaling pathway implicated in schizophrenia risk Schizophrenia Research ·Thorsten M. Kranz, Ray Goetz, Julie Walsh‐Messinger, Deborah Goetz, Daniel Antonius, Igor Dolgalev, Adriana Heguy, Marco Seandel, Dolores Malaspina, Moses V. Chao	2015	21
10	Whole-Exome Sequencing Reveals Frequent Genetic Alterations in BAP1 , NF2 , CDKN2A , and CUL1 in Malignant Pleural Mesothelioma Cancer Research ·Guangwu Guo, Juliann Chmielecki, Chandra Goparaju, Adriana Heguy, Igor Dolgalev, Michele Carbone, Sara Seepo, Matthew Meyerson, Harvey I. Pass	2014	229
11	RHOA-FAK Is a Required Signaling Axis for the Maintenance of KRAS-Driven Lung Adenocarcinomas Cancer Discovery ·Georgia Konstantinidou, Giorgio Ramadori, Francesca Torti, Kim Kangasniemi, Rachel E. Ramirez, Yiran Cai, Carmen Behrens, Michael T. Dellinger, Rolf A. Brekken, Ignacio I. Wistuba, Adriana Heguy, Julie Teruya‐Feldstein, Pier Paolo Scaglioni	2013	91
12	Genome Sequencing Identifies a Basis for Everolimus Sensitivity Science ·Gopa Iyer, Aphrothiti J. Hanrahan, Matthew I. Milowsky, Hikmat Al‐Ahmadie, Sasinya N. Scott, Manickam Janakiraman, Mono Pirun, Chris Sander, Nicholas D. Socci, Irina Ostrovnaya, Agnès Viale, Adriana Heguy, Luke Peng, Timothy A. Chan, Bernard H. Bochner, Dean F. Bajorin, Michael F. Berger, Barry S. Taylor, David B. Solit Hit paper breakdown →	2012	480
13	IDH Mutation and Neuroglial Developmental Features Define Clinically Distinct Subclasses of Lower Grade Diffuse Astrocytic Glioma Clinical Cancer Research ·Daniel Gorovets, Kasthuri Kannan, Ronglai Shen, Edward R. Kastenhuber, Nasrin Islamdoust, Carl Campos, Elena Pentsova, Adriana Heguy, Suresh C. Jhanwar, Ingo K. Mellinghoff, Timothy A. Chan, Jason T. Huse	2012	114
14	Phase II Trial of Temozolomide in Patients with Relapsed Sensitive or Refractory Small Cell Lung Cancer, with Assessment of Methylguanine-DNA Methyltransferase as a Potential Biomarker Clinical Cancer Research ·M. Catherine Pietanza, Kyuichi Kadota, Kety Huberman, Camelia S. Sima, John J. Fiore, Dyana K. Sumner, William D. Travis, Adriana Heguy, Michelle S. Ginsberg, Andrei I. Holodny, Timothy A. Chan, Naiyer A. Rizvi, Christopher G. Azzoli, Gregory J. Riely, Mark G. Kris, Lee M. Krug	2012	122
15	Genomic Complexity and AKT Dependence in Serous Ovarian Cancer Cancer Discovery ·Aphrothiti J. Hanrahan, Nikolaus Schultz, Maggie L. Westfal, Rita A. Sakr, Dilip D. Giri, Stefano Scarperi, Manickam Janikariman, Narciso Olvera, Ellen V. Stevens, Qing‐Bai She, Carol Aghajanian, Tari A. King, Elisa de Stanchina, David R. Spriggs, Adriana Heguy, Barry S. Taylor, Chris Sander, Neal Rosen, Douglas A. Levine, David B. Solit	2011	88
16	Genomic Deregulation during Metastasis of Renal Cell Carcinoma Implements a Myofibroblast-Like Program of Gene Expression Cancer Research ·Miguel A. López-Lago, Venkata J. Thodima, Asha Guttapalli, Timothy A. Chan, Adriana Heguy, Ana M. Molina, Victor E. Reuter, Robert J. Motzer, R. S. K. Chaganti	2010	27
17	Genetic Analysis of Transforming Events That Convert Chronic Myeloproliferative Neoplasms to Leukemias Cancer Research ·Omar Abdel‐Wahab, Taghi Manshouri, Jay Patel, Kelly L. Harris, JinJuan Yao, Cyrus V. Hedvat, Adriana Heguy, Carlos Bueso-Ramos, Hagop M. Kantarjian, Ross L. Levine, Srđan Verstovšek	2010	227
18	PIK3CA Mutation Associates with Improved Outcome in Breast Cancer Clinical Cancer Research ·Kevin Kalinsky, Lindsay M. Jacks, Adriana Heguy, Sujata Patil, Marija Drobnjak, Umesh Bhanot, Cyrus V. Hedvat, Tiffany A. Traina, David B. Solit, William L. Gerald, Mary Ellen Moynahan	2009	299
19	Comprehensive Genomic Analysis Reveals Clinically Relevant Molecular Distinctions between Thymic Carcinomas and Thymomas Clinical Cancer Research ·Nicolas Girard, Ronglai Shen, Tianhua Guo, Maureen F. Zakowski, Adriana Heguy, Gregory J. Riely, James Huang, Christopher Lau, Alex Lash, Marc Ladanyi, Agnès Viale, Cristina R. Antonescu, William D. Travis, Valerie W. Rusch, Mark G. Kris, William Pao	2009	147
20	Mutational Profile of Advanced Primary and Metastatic Radioactive Iodine-Refractory Thyroid Cancers Reveals Distinct Pathogenetic Roles for BRAF, PIK3CA , and AKT1 Cancer Research ·Julio C. Ricarte‐Filho, Mabel Ryder, Dhananjay Chitale, Michael Rivera, Adriana Heguy, Marc Ladanyi, Manickam Janakiraman, David B. Solit, Jeffrey A. Knauf, R. Michael Tuttle, Ronald Ghossein, James A. Fagin	2009	420

About Adriana Heguy

Adriana Heguy is a scholar working on Cancer Research, Genetics, Molecular Biology, Oncology and Immunology, having authored 178 papers that have together received 14.0k indexed citations. Recurring topics across this work include Cancer Genomics and Diagnostics (14 papers), Epigenetics and DNA Methylation (13 papers), Gut microbiota and health (12 papers), Glioma Diagnosis and Treatment (10 papers), Trace Elements in Health (9 papers), Alzheimer's disease research and treatments (9 papers), PI3K/AKT/mTOR signaling in cancer (8 papers) and Heavy Metal Exposure and Toxicity (8 papers). The work is most often cited by research in Genetics (2.3k citations), Cancer Research (2.9k citations), Oncology (3.2k citations), Hematology (1.2k citations) and Molecular Biology (6.9k citations). Adriana Heguy has collaborated with scholars based in United States, Italy and Germany. Frequent co-authors include Michael Karin, Agnès Viale, Ronald G. Crystal, Robert G. Roeder, Ross L. Levine, Robert I. Richards, Igor Dolgalev, Claus Scheidereit, Jason T. Huse and David B. Solit. Their work appears in journals such as Cancer Research, Journal of Clinical Oncology, Molecular and Cellular Biology, Blood and Clinical Cancer Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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