Tim D. Spector

173.0k total citations · 18 hit papers
722 papers, 52.2k citations indexed

About

Tim D. Spector is a scholar working on Molecular Biology, Rheumatology and Genetics. According to data from OpenAlex, Tim D. Spector has authored 722 papers receiving a total of 52.2k indexed citations (citations by other indexed papers that have themselves been cited), including 202 papers in Molecular Biology, 146 papers in Rheumatology and 145 papers in Genetics. Recurrent topics in Tim D. Spector's work include Osteoarthritis Treatment and Mechanisms (106 papers), Genetic Associations and Epidemiology (73 papers) and Bone health and osteoporosis research (71 papers). Tim D. Spector is often cited by papers focused on Osteoarthritis Treatment and Mechanisms (106 papers), Genetic Associations and Epidemiology (73 papers) and Bone health and osteoporosis research (71 papers). Tim D. Spector collaborates with scholars based in United Kingdom, United States and Australia. Tim D. Spector's co-authors include Alex J. MacGregor, Ana M. Valdes, Deborah Hart, Harold Snieder, Jordana T. Bell, David Doyle, Claire J. Steves, Cristina Menni, Lynn Cherkas and Toby Andrew and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Tim D. Spector

710 papers receiving 50.8k citations

Hit Papers

Osteoarthritis: New Insights. Part 1: The Disease and Its... 1996 2026 2006 2016 2000 2018 2004 2020 2016 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Osteoarthritis: New Insights. Part 1: The Disease and Its Risk Factors
    2000 1.9k citations Tim D. Spector, Leena Sharma et al. profile →
  2. Role of the gut microbiota in nutrition and health
    2018 1.6k citations Ana M. Valdes, Tim D. Spector et al. profile →
  3. The Effects of Strontium Ranelate on the Risk of Vertebral Fracture in Women with Postmenopausal Osteoporosis
    2004 1.2k citations Tim D. Spector et al. profile →
  4. Real-time tracking of self-reported symptoms to predict potential COVID-19
    2020 847 citations Cristina Menni, Ana M. Valdes et al. profile →
  5. Genetic Determinants of the Gut Microbiome in UK Twins
    2016 718 citations Julia K. Goodrich, Michelle Beaumont et al. profile →
  6. Proton pump inhibitors alter the composition of the gut microbiota
    2015 627 citations Matthew Jackson, Julia K. Goodrich et al. profile →
  7. Effect of Diet on the Gut Microbiota: Rethinking Intervention Duration
    2019 559 citations Emily R. Leeming, Tim D. Spector et al. profile →
  8. Predicting brain age with deep learning from raw imaging data results in a reliable and heritable biomarker
    2017 523 citations Claire J. Steves, Tim D. Spector et al. profile →
  9. Genetic influences on osteoarthritis in women: a twin study
    1996 521 citations Tim D. Spector et al. profile →
  10. Interplay between the human gut microbiome and host metabolism
    2019 501 citations Robert P. Mohney, Jordana T. Bell et al. profile →
  11. Obesity accelerates epigenetic aging of human liver
    2014 492 citations Jordana T. Bell, Tim D. Spector et al. Proceedings of the National Academy of Sciences profile →
  12. The fecal metabolome as a functional readout of the gut microbiome
    2018 481 citations Jonas Zierer, Matthew Jackson et al. profile →
  13. A genome-wide perspective of genetic variation in human metabolism
    2009 475 citations Guangju Zhai, Bernet Kato et al. profile →
  14. Lipidomics Profiling and Risk of Cardiovascular Disease in the Prospective Population-Based Bruneck Study
    2014 418 citations Massimo Mangino, Cristina Menni et al. profile →
  15. Gut microbiota associations with common diseases and prescription medications in a population-based cohort
    2018 418 citations Matthew Jackson, Jonas Zierer et al. profile →
  16. COVID-19 vaccine waning and effectiveness and side-effects of boosters: a prospective community study from the ZOE COVID Study
    2022 204 citations Cristina Menni, Lorenzo Polidori et al. profile →
  17. Effects of a personalized nutrition program on cardiometabolic health: a randomized controlled trial
    2024 49 citations Kate Bermingham, Inbar Linenberg et al. profile →
  18. Gut microbiome signatures of vegan, vegetarian and omnivore diets and associated health outcomes across 21,561 individuals
    2025 36 citations Kate Bermingham, Sarah Berry et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Tim D. Spector United Kingdom 119 16.7k 10.3k 8.4k 7.2k 6.9k 722 52.2k
Alan J. Silman United Kingdom 104 5.1k 0.3× 11.5k 1.1× 3.5k 0.4× 8.4k 1.2× 3.8k 0.5× 424 46.4k
Peter W.F. Wilson United States 156 10.9k 0.7× 8.8k 0.8× 13.3k 1.6× 31.0k 4.3× 7.7k 1.1× 646 110.5k
Simon G. Thompson United Kingdom 78 7.6k 0.5× 4.3k 0.4× 7.7k 0.9× 16.4k 2.3× 9.2k 1.3× 223 90.9k
Yehuda Shoenfeld Israel 115 8.2k 0.5× 23.0k 2.2× 4.2k 0.5× 6.6k 0.9× 6.2k 0.9× 1.6k 63.1k
David J. Hunter United States 143 13.6k 0.8× 34.2k 3.3× 9.3k 1.1× 24.4k 3.4× 10.5k 1.5× 1.4k 97.1k
L. Adrienne Cupples United States 112 7.9k 0.5× 2.0k 0.2× 8.3k 1.0× 6.6k 0.9× 7.1k 1.0× 539 43.4k
Luigi Ferrucci United States 158 17.2k 1.0× 4.2k 0.4× 43.9k 5.2× 11.7k 1.6× 5.0k 0.7× 1.6k 128.0k
Jaakko Kaprio Finland 117 8.6k 0.5× 2.0k 0.2× 12.3k 1.5× 3.9k 0.5× 9.6k 1.4× 1.2k 61.3k
M. Hassan Murad United States 146 7.7k 0.5× 2.8k 0.3× 6.3k 0.7× 24.1k 3.3× 5.0k 0.7× 978 103.8k
Jonathan J Deeks United Kingdom 92 5.5k 0.3× 3.7k 0.4× 6.7k 0.8× 20.0k 2.8× 3.0k 0.4× 368 96.6k

Countries citing papers authored by Tim D. Spector

Since Specialization
Citations

This map shows the geographic impact of Tim D. Spector's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tim D. Spector with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tim D. Spector more than expected).

Fields of papers citing papers by Tim D. Spector

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tim D. Spector. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tim D. Spector. The network helps show where Tim D. Spector may publish in the future.

Co-authorship network of co-authors of Tim D. Spector

This figure shows the co-authorship network connecting the top 25 collaborators of Tim D. Spector. A scholar is included among the top collaborators of Tim D. Spector based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Tim D. Spector. Tim D. Spector is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Moustafa, Julia S. El-Sayed, Craig A. Glastonbury, Tim D. Spector, et al.. (2025). Quantification of heavy metal exposure in a British population cohort links total mercury levels in plasma with skin tissue-specific changes in mitochondrial-related gene expression. The Science of The Total Environment. 963. 178427–178427.
2.
Bermingham, Kate, Inbar Linenberg, Lorenzo Polidori, et al.. (2023). Improved Cardiometabolic Health Using a Personalised Nutrition Approach: The ZOE METHOD Study. SHILAP Revista de lepidopterología. 55–55.
3.
Leeming, Emily R., Panayiotis Louca, Rachel Gibson, et al.. (2021). The complexities of the diet-microbiome relationship: advances and perspectives. Genome Medicine. 13(1). 10–10. 69 indexed citations
4.
Cuesta‐Zuluaga, Jacobo de la, Tim D. Spector, Nicholas D. Youngblut, & Ruth E. Ley. (2021). Genomic Insights into Adaptations of Trimethylamine-Utilizing Methanogens to Diverse Habitats, Including the Human Gut. mSystems. 6(1). 29 indexed citations
5.
Chen, Lingxiao, Maja R Radojčić, Paula R. Beckenkamp, et al.. (2021). Association of Lumbar Spine Radiographic Changes With Severity of Back Pain–Related Disability Among Middle-aged, Community-Dwelling Women. JAMA Network Open. 4(5). e2110715–e2110715. 13 indexed citations
6.
Hysi, Pirro G., Tim D. Spector, Wiro J. Niessen, et al.. (2018). Ensemble landmarking of 3D facial surface scans. Scientific Reports. 8(1). 12–12. 79 indexed citations
7.
Crouch, Daniel J. M., Bruce Winney, William Christmas, et al.. (2018). Genetics of the human face: Identification of large-effect single gene variants. Proceedings of the National Academy of Sciences. 115(4). E676–E685. 47 indexed citations
8.
Mullin, Benjamin H., Jing Hua Zhao, Suzanne J. Brown, et al.. (2017). Genome-wide association study meta-analysis for quantitative ultrasound parameters of bone identifies five novel loci for broadband ultrasound attenuation. Human Molecular Genetics. 26(14). 2791–2802. 28 indexed citations
9.
Menni, Cristina, Jonas Zierer, Tess Pallister, et al.. (2017). Omega-3 fatty acids correlate with gut microbiome diversity and production of N-carbamylglutamate in middle aged and elderly women. Scientific Reports. 7(1). 11079–11079. 178 indexed citations
10.
Roos, Leonie, Johanna K. Sandling, Christopher G. Bell, et al.. (2016). Higher Nevus Count Exhibits a Distinct DNA Methylation Signature in Healthy Human Skin: Implications for Melanoma. Journal of Investigative Dermatology. 137(4). 910–920. 18 indexed citations
11.
Liu, Yansheng, Alfonso Buil, Ben C. Collins, et al.. (2015). Quantitative variability of 342 plasma proteins in a human twin population. Molecular Systems Biology. 11(2). 786–786. 236 indexed citations
12.
Barrios, Clara, Michelle Beaumont, Tess Pallister, et al.. (2015). Gut-Microbiota-Metabolite Axis in Early Renal Function Decline. PLoS ONE. 10(8). e0134311–e0134311. 143 indexed citations
13.
Brown, Andrew, Zhihao Ding, Ana Viñuela, et al.. (2015). Pathway-Based Factor Analysis of Gene Expression Data Produces Highly Heritable Phenotypes That Associate with Age. G3 Genes Genomes Genetics. 5(5). 839–847. 7 indexed citations
14.
Jern, Patrick, Lars Westberg, A Johansson, et al.. (2014). A Study of Possible Associations Between Single Nucleotide Polymorphisms in the Estrogen Receptor 2 Gene and Female Sexual Desire. The Journal of Sexual Medicine. 12(3). 676–684. 10 indexed citations
15.
Harris, Juliette, Lynn Cherkas, Bernet Kato, Julia R. Heiman, & Tim D. Spector. (2008). Normal Variations in Personality are Associated with Coital Orgasmic Infrequency in Heterosexual Women: A Population-Based Study. The Journal of Sexual Medicine. 5(5). 1177–1183. 80 indexed citations
16.
Liew, Steven, Clare Gilbert, Jemima E. Mellerio, et al.. (2006). Effects of 6 month lutein supplementation on macular pigment levels, measured by two methods, fundus autofluorescence and heterchromatic flicker photometry.. Investigative Ophthalmology & Visual Science. 47(13). 3794–3794. 1 indexed citations
17.
Zhai, Guangju, David Hart, Bernet Kato, Leena Sharma, & Tim D. Spector. (2006). Genetic contribution to knee radiographic osteoarthritis and knee alignment: A classical twin study. Research Portal (King's College London). 54(9). 1 indexed citations
18.
Spector, Tim D., et al.. (2003). Risedronate produces disease modification and symptomatic benefit in the treatment of knee osteoarthritis: results from the BRISK study. Research Portal (King's College London). 48(12). 3650–3651. 8 indexed citations
19.
Reed, Peter, et al.. (2002). Large-scale genome-wide screen of female twin pairs confirms presence of QTLs for BMD at 1p36 and 3p21. Journal of Bone and Mineral Research. 17. 2 indexed citations
20.
Garner, C., Thanusak Tatu, Laurence Gamé, et al.. (1999). A candidate gene study of F cell levels in sibling pairs using a joint linkage and association analysis.. Blood. 94. 2 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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