Theodore R. Holman

6.8k total citations
116 papers, 4.4k citations indexed

About

Theodore R. Holman is a scholar working on Molecular Biology, Pharmacology and Organic Chemistry. According to data from OpenAlex, Theodore R. Holman has authored 116 papers receiving a total of 4.4k indexed citations (citations by other indexed papers that have themselves been cited), including 50 papers in Molecular Biology, 36 papers in Pharmacology and 26 papers in Organic Chemistry. Recurrent topics in Theodore R. Holman's work include Eicosanoids and Hypertension Pharmacology (22 papers), Inflammatory mediators and NSAID effects (22 papers) and Bioactive Compounds and Antitumor Agents (15 papers). Theodore R. Holman is often cited by papers focused on Eicosanoids and Hypertension Pharmacology (22 papers), Inflammatory mediators and NSAID effects (22 papers) and Bioactive Compounds and Antitumor Agents (15 papers). Theodore R. Holman collaborates with scholars based in United States, Chile and Canada. Theodore R. Holman's co-authors include Victor Kenyon, Joshua D. Deschamps, Stephanie Whitman, Michael Holinstat, Phillip Crews, David J. Maloney, Ajit Jadhav, Anton Simeonov, Christopher T. Walsh and Aaron T. Wecksler and has published in prestigious journals such as Journal of the American Chemical Society, Blood and PLoS ONE.

In The Last Decade

Theodore R. Holman

116 papers receiving 4.3k citations

Peers

Countries citing papers authored by Theodore R. Holman

Since Specialization

Citations

This map shows the geographic impact of Theodore R. Holman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Theodore R. Holman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Theodore R. Holman more than expected).

Fields of papers citing papers by Theodore R. Holman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Theodore R. Holman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Theodore R. Holman. The network helps show where Theodore R. Holman may publish in the future.

Co-authorship network of co-authors of Theodore R. Holman

This figure shows the co-authorship network connecting the top 25 collaborators of Theodore R. Holman. A scholar is included among the top collaborators of Theodore R. Holman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Theodore R. Holman. Theodore R. Holman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Cryo-EM structures of human arachidonate 12S-lipoxygenase bound to endogenous and exogenous inhibitors 2023 ·Blood ·Jesse I. Mobbs, (unknown), (unknown), (unknown), Hariprasad Venugopal, Theodore R. Holman, Michael Holinstat, David M. Thal, Alisa Glukhova	11
2	Non-Enzymatic Role of Platelet 12-LOX in Platelet Activation 2023 ·Blood ·(unknown), (unknown), Wan‐Chen Tsai, Theodore R. Holman, Michael Holinstat	1
3	Inhibitory Investigations of Acyl-CoA Derivatives against Human Lipoxygenase Isozymes 2023 ·International Journal of Molecular Sciences ·(unknown), Kevin Yang, Alisa Glukhova, Michael Holinstat, Theodore R. Holman	4
4	In Vitro Biosynthetic Pathway Investigations of Neuroprotectin D1 (NPD1) and Protectin DX (PDX) by Human 12-Lipoxygenase, 15-Lipoxygenase-1, and 15-Lipoxygenase-2 2021 ·Biochemistry ·Wan‐Chen Tsai, Chakrapani Kalyanaraman, Adriana Yamaguchi, Michael Holinstat, Matthew P. Jacobson, Theodore R. Holman	19
5	Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2 2021 ·Bioorganic & Medicinal Chemistry ·Wan‐Chen Tsai, Nathaniel C. Gilbert, (unknown), (unknown), Steve Perry, Chakrapani Kalyanaraman, Adam Yasgar, Ganesha Rai, Anton Simeonov, Ajit Jadhav, Melissa Standley, Hsiau‐Wei Lee, Phillip Crews, Anthony T. Iavarone, Matthew P. Jacobson, David B. Neau, Adam R. Offenbacher, Marcia E. Newcomer, Theodore R. Holman	19
6	Mutagenesis, Hydrogen–Deuterium Exchange, and Molecular Docking Investigations Establish the Dimeric Interface of Human Platelet-Type 12-Lipoxygenase 2021 ·Biochemistry ·Wan‐Chen Tsai, Ansari M. Aleem, (unknown), Wilian A. Cortopassi, Chakrapani Kalyanaraman, (unknown), Anthony T. Iavarone, Ewa Skrzypczak‐Jankun, Matthew P. Jacobson, Adam R. Offenbacher, Theodore R. Holman	9
7	Role of Human 15-Lipoxygenase-2 in the Biosynthesis of the Lipoxin Intermediate, 5S,15S-diHpETE, Implicated with the Altered Positional Specificity of Human 15-Lipoxygenase-1 2020 ·Biochemistry ·Steve Perry, Thomas Horn, Benjamin E. Tourdot, Adriana Yamaguchi, Chakrapani Kalyanaraman, (unknown), (unknown), Michael Holinstat, Matthew P. Jacobson, Theodore R. Holman	14
8	Biosynthesis of the Maresin Intermediate, 13S,14S-Epoxy-DHA, by Human 15-Lipoxygenase and 12-Lipoxygenase and Its Regulation through Negative Allosteric Modulators 2020 ·Biochemistry ·Cody J. Freedman, (unknown), Benjamin E. Tourdot, Chakrapani Kalyanaraman, Steve Perry, Michael Holinstat, Matthew P. Jacobson, Theodore R. Holman	28
9	Omega-6 DPA and its 12-lipoxygenase–oxidized lipids regulate platelet reactivity in a nongenomic PPARα-dependent manner 2020 ·Blood Advances ·Jennifer Yeung, Reheman Adili, Adriana Yamaguchi, Cody J. Freedman, (unknown), (unknown), Aditi Das, Theodore R. Holman, Michael Holinstat	20
10	DHA 12‐LOX‐derived oxylipins regulate platelet activation and thrombus formation through a PKA‐dependent signaling pathway 2020 ·Journal of Thrombosis and Haemostasis ·Adriana Yamaguchi, (unknown), Cody J. Freedman, Melissa Standley, Timothy N. Hoang, Reheman Adili, Wan‐Chen Tsai, (unknown), Theodore R. Holman, Michael Holinstat	27
11	Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis 2020 ·Redox Biology ·Tamil S. Anthonymuthu, Yulia Y. Tyurina, Wan‐Yang Sun, Karolina Mikulska‐Ruminska, Indira H. Shrivastava, Vladimir A. Tyurin, (unknown), Haider H. Dar, Andrew P. VanDemark, Theodore R. Holman, Yoel Sadovsky, Brent R. Stockwell, Rong‐Rong He, İvet Bahar, Hülya Bayır, Valerian E. Kagan	104
12	Probing the Electrostatic and Steric Requirements for Substrate Binding in Human Platelet-Type 12-Lipoxygenase 2018 ·Biochemistry ·Ansari M. Aleem, Wan‐Chen Tsai, (unknown), (unknown), Joshua D. Deschamps, Chakrapani Kalyanaraman, Matthew P. Jacobson, Theodore R. Holman	16
13	Azole Antifungal Sensitivity of Sterol 14α-Demethylase (CYP51) and CYP5218 from Malassezia globosa 2016 ·Scientific Reports ·Andrew G. S. Warrilow, Claire Price, Josie E. Parker, Nicola J. Rolley, (unknown), David D. Hughes, Vera Thoss, W. David Nes, Diane Kelly, Theodore R. Holman, Steven L. Kelly	16
14	12-lipoxygenase activity plays an important role in PAR4 and GPVI-mediated platelet reactivity 2013 ·Thrombosis and Haemostasis ·Jennifer Yeung, Patrick L. Apopa, (unknown), (unknown), Ganesha Rai, Anton Simeonov, Ajit Jadhav, (unknown), David J. Maloney, Olivier Boutaud, Theodore R. Holman, Michael Holinstat	51
15	Discovery of a Novel Dual Fungal CYP51/Human 5-Lipoxygenase Inhibitor: Implications for Anti-Fungal Therapy 2013 ·PLoS ONE ·(unknown), Ganesha Rai, Andrew G. S. Warrilow, Steve Perry, (unknown), Ajit Jadhav, Anton Simeonov, Josie E. Parker, Diane Kelly, David J. Maloney, Steven L. Kelly, Theodore R. Holman	18
16	Differential contribution of lipoxygenase isozymes to nigrostriatal vulnerability 2012 ·Neuroscience ·Vivian Chou, Theodore R. Holman, Amy Manning-Bog	21
17	Substrate specificity effects of lipoxygenase products and inhibitors on soybean lipoxygenase-1 2009 ·Bioorganic & Medicinal Chemistry ·Aaron T. Wecksler, Natalie K. Garcia, Theodore R. Holman	23
18	Synthesis of 11-thialinoleic acid and 14-thialinoleic acid, inhibitors of soybean and human lipoxygenases 2008 ·Organic & Biomolecular Chemistry ·Cyril Jacquot, (unknown), (unknown), Theodore R. Holman, Wilfred A. van der Donk	6
19	Structure–activity relationship studies of flavonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2 2007 ·Bioorganic & Medicinal Chemistry ·(unknown), Rachana Ohri, Victor Kenyon, Theodore R. Holman, Silvia Sepúlveda‐Boza	68
20	Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases 2006 ·Bioorganic & Medicinal Chemistry ·Joshua D. Deschamps, Victor Kenyon, Theodore R. Holman	135

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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