Michael Holinstat

6.1k total citations · 2 hit papers
116 papers, 4.5k citations indexed

About

Michael Holinstat is a scholar working on Cardiology and Cardiovascular Medicine, Hematology and Biochemistry. According to data from OpenAlex, Michael Holinstat has authored 116 papers receiving a total of 4.5k indexed citations (citations by other indexed papers that have themselves been cited), including 41 papers in Cardiology and Cardiovascular Medicine, 39 papers in Hematology and 32 papers in Biochemistry. Recurrent topics in Michael Holinstat's work include Antiplatelet Therapy and Cardiovascular Diseases (35 papers), Eicosanoids and Hypertension Pharmacology (32 papers) and Platelet Disorders and Treatments (31 papers). Michael Holinstat is often cited by papers focused on Antiplatelet Therapy and Cardiovascular Diseases (35 papers), Eicosanoids and Hypertension Pharmacology (32 papers) and Platelet Disorders and Treatments (31 papers). Michael Holinstat collaborates with scholars based in United States, Australia and Sweden. Michael Holinstat's co-authors include Jennifer Yeung, Reheman Adili, Asrar B. Malik, Dolly Mehta, Benjamin E. Tourdot, Heidi E. Hamm, Theodore R. Holman, Richard D. Minshall, Jennifer Yeung and Leonard C. Edelstein and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Michael Holinstat

112 papers receiving 4.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Normal platelet function

2017 303 citations Michael Holinstat profile →
An age-progressive platelet differentiation path from hematopoietic stem cells causes exacerbated thrombosis

2024 49 citations Michael Holinstat et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Michael Holinstat United States	39	1.6k	1.1k	864	584	461	116	4.5k
Stepan Gambaryan Germany	42	2.7k 1.7×	1.3k 1.1×	1.5k 1.7×	347 0.6×	316 0.7×	159	6.2k
John Hwa United States	48	3.6k 2.3×	322 0.3×	840 1.0×	341 0.6×	482 1.0×	130	6.6k
Mariarosaria Bucci Italy	43	2.3k 1.5×	550 0.5×	580 0.7×	1.5k 2.6×	305 0.7×	113	5.7k
Aı̈da Habib France	35	1.9k 1.2×	330 0.3×	842 1.0×	713 1.2×	466 1.0×	87	4.8k
Edward P. Feener United States	43	2.8k 1.8×	432 0.4×	1.4k 1.6×	211 0.4×	393 0.9×	94	6.7k
Fumiko Sekiguchi Japan	40	1.6k 1.0×	443 0.4×	302 0.3×	866 1.5×	345 0.7×	174	5.1k
Harald Esterbauer Austria	41	2.7k 1.7×	375 0.3×	434 0.5×	367 0.6×	415 0.9×	94	5.5k
Albert Smolenski Germany	37	2.6k 1.7×	556 0.5×	1.4k 1.6×	286 0.5×	278 0.6×	67	5.0k
Laurent Audoly United States	38	1.8k 1.1×	288 0.3×	732 0.8×	683 1.2×	433 0.9×	69	5.9k
Lee Chao United States	55	3.3k 2.1×	1.1k 1.0×	1.6k 1.9×	126 0.2×	677 1.5×	208	7.9k

Countries citing papers authored by Michael Holinstat

Since Specialization

Citations

This map shows the geographic impact of Michael Holinstat's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael Holinstat with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael Holinstat more than expected).

Fields of papers citing papers by Michael Holinstat

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael Holinstat. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael Holinstat. The network helps show where Michael Holinstat may publish in the future.

Co-authorship network of co-authors of Michael Holinstat

This figure shows the co-authorship network connecting the top 25 collaborators of Michael Holinstat. A scholar is included among the top collaborators of Michael Holinstat based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael Holinstat. Michael Holinstat is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Kulkarni, Paresh P., Ravi Kumar Alluri, Alona A. Merkulova, et al.. (2025). Protection of β2GPI-deficient mice from thrombosis reflects a defect in PAR3-facilitated platelet activation. Blood. 145(18). 2086–2099. 1 indexed citations

Patel, Pranav M., et al.. (2024). Observational Analyses of Ex Vivo Native American Platelet Responses. International Journal of Molecular Sciences. 25(22). 11990–11990. 1 indexed citations

Sznitman, Josué, et al.. (2024). Clot Accumulation in 3D Microfluidic Bifurcating Microvasculature Network. Micromachines. 15(8). 988–988. 3 indexed citations

Özpolat, Tahsin, S. Lawrence Bailey, Reheman Adili, et al.. (2023). Loss of 12-Lipoxygenase Improves the Post-Transfusion Function of Stored Platelets. Arteriosclerosis Thrombosis and Vascular Biology. 43(10). 1990–2007. 5 indexed citations

Yamaguchi, Adriana, et al.. (2023). Antiplatelet strategies: past, present, and future. Journal of Thrombosis and Haemostasis. 21(12). 3317–3328. 14 indexed citations

Mobbs, Jesse I., Hariprasad Venugopal, Theodore R. Holman, et al.. (2023). Cryo-EM structures of human arachidonate 12S-lipoxygenase bound to endogenous and exogenous inhibitors. Blood. 142(14). 1233–1242. 11 indexed citations

Yamaguchi, Adriana, Sylviane Lambert, Catherine Luke, et al.. (2023). The oxylipin analog CS585 prevents platelet activation and thrombosis through activation of the prostacyclin receptor. Blood. 142(18). 1556–1569. 9 indexed citations

Tsai, Wan‐Chen, et al.. (2023). Non-Enzymatic Role of Platelet 12-LOX in Platelet Activation. Blood. 142(Supplement 1). 5397–5397. 1 indexed citations

Song, Shuang, David J. Pinsky, Kathryn E. Uhrich, et al.. (2023). Cargo-free particles divert neutrophil-platelet aggregates to reduce thromboinflammation. Nature Communications. 14(1). 2462–2462. 16 indexed citations

10.

Yang, Kevin, et al.. (2023). Inhibitory Investigations of Acyl-CoA Derivatives against Human Lipoxygenase Isozymes. International Journal of Molecular Sciences. 24(13). 10941–10941. 4 indexed citations

11.

Melvin, William J., Christopher O. Audu, Wei-Sheng Wu, et al.. (2022). The histone methyltransferase MLL1/KMT2A in monocytes drives coronavirus-associated coagulopathy and inflammation. Blood. 141(7). 725–742. 10 indexed citations

12.

Frame, David, Thomas Braun, Mary Maliarik, et al.. (2022). Defibrotide Therapy for SARS-CoV-2 ARDS. CHEST Journal. 162(2). 346–355. 11 indexed citations

13.

Tsai, Wan‐Chen, Chakrapani Kalyanaraman, Adriana Yamaguchi, et al.. (2021). In Vitro Biosynthetic Pathway Investigations of Neuroprotectin D1 (NPD1) and Protectin DX (PDX) by Human 12-Lipoxygenase, 15-Lipoxygenase-1, and 15-Lipoxygenase-2. Biochemistry. 60(22). 1741–1754. 19 indexed citations

14.

Pitt, Bertram, Nadia R. Sutton, Zhong Wang, Sascha N. Goonewardena, & Michael Holinstat. (2021). Potential repurposing of the HDAC inhibitor valproic acid for patients with COVID-19. European Journal of Pharmacology. 898. 173988–173988. 35 indexed citations

15.

Yeung, Jennifer, Reheman Adili, Rong Luo, et al.. (2020). GPR56/ADGRG1 is a platelet collagen-responsive GPCR and hemostatic sensor of shear force. Proceedings of the National Academy of Sciences. 117(45). 28275–28286. 66 indexed citations

16.

Perry, Steve, Thomas Horn, Benjamin E. Tourdot, et al.. (2020). Role of Human 15-Lipoxygenase-2 in the Biosynthesis of the Lipoxin Intermediate, 5S,15S-diHpETE, Implicated with the Altered Positional Specificity of Human 15-Lipoxygenase-1. Biochemistry. 59(42). 4118–4130. 14 indexed citations

17.

Freedman, Cody J., Benjamin E. Tourdot, Chakrapani Kalyanaraman, et al.. (2020). Biosynthesis of the Maresin Intermediate, 13S,14S-Epoxy-DHA, by Human 15-Lipoxygenase and 12-Lipoxygenase and Its Regulation through Negative Allosteric Modulators. Biochemistry. 59(19). 1832–1844. 28 indexed citations

18.

Yeung, Jennifer, Reheman Adili, Adriana Yamaguchi, et al.. (2020). Omega-6 DPA and its 12-lipoxygenase–oxidized lipids regulate platelet reactivity in a nongenomic PPARα-dependent manner. Blood Advances. 4(18). 4522–4537. 20 indexed citations

19.

Adili, Reheman, et al.. (2018). Modified two-step emulsion solvent evaporation technique for fabricating biodegradable rod-shaped particles in the submicron size range. Journal of Colloid and Interface Science. 518. 174–183. 13 indexed citations

20.

Shestopalov, Ilya, Yang Liu, Andy H. Vo, et al.. (2018). Nfe2 is dispensable for early but required for adult thrombocyte formation and function in zebrafish. Blood Advances. 2(23). 3418–3427. 12 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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